A citation-based method for searching scientific literature

Richard Gordon, Eduardo A Albornoz, Daniel C Christie, Monica R Langley, Vinod Kumar, Susanna Mantovani, Avril A B Robertson, Mark S Butler, Dominic B Rowe, Luke A O'Neill, Anumantha G Kanthasamy, Kate Schroder, Matthew A Cooper, Trent M Woodruff. Sci Transl Med 2018
Times Cited: 250







List of co-cited articles
1323 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
32

MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration.
Eunju Lee, Inhwa Hwang, Sangjun Park, Sujeong Hong, Boreum Hwang, Yoeseph Cho, Junghyun Son, Je-Wook Yu. Cell Death Differ 2019
124
29

Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies.
Gaia Codolo, Nicoletta Plotegher, Tommaso Pozzobon, Marco Brucale, Isabella Tessari, Luigi Bubacco, Marina de Bernard. PLoS One 2013
320
29

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
25

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.
C Dempsey, A Rubio Araiz, K J Bryson, O Finucane, C Larkin, E L Mills, A A B Robertson, M A Cooper, L A J O'Neill, M A Lynch. Brain Behav Immun 2017
223
23

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
23

Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.
Yiqing Yan, Wei Jiang, Lei Liu, Xiaqiong Wang, Chen Ding, Zhigang Tian, Rongbin Zhou. Cell 2015
519
20

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia.
Changyoun Kim, Dong-Hwan Ho, Ji-Eun Suk, Sungyong You, Sarah Michael, Junghee Kang, Sung Joong Lee, Eliezer Masliah, Daehee Hwang, He-Jin Lee,[...]. Nat Commun 2013
450
17

Inflammasome signalling in brain function and neurodegenerative disease.
Michael T Heneka, Róisín M McManus, Eicke Latz. Nat Rev Neurosci 2018
261
16

Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.
Nikhil Panicker, Souvarish Sarkar, Dilshan S Harischandra, Matthew Neal, Tae-In Kam, Huajun Jin, Hariharan Saminathan, Monica Langley, Adhithiya Charli, Manikandan Samidurai,[...]. J Exp Med 2019
77
20

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.
Carmen Venegas, Sathish Kumar, Bernardo S Franklin, Tobias Dierkes, Rebecca Brinkschulte, Dario Tejera, Ana Vieira-Saecker, Stephanie Schwartz, Francesco Santarelli, Markus P Kummer,[...]. Nature 2017
363
16

NLRP3 inflammasome activation drives tau pathology.
Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera,[...]. Nature 2019
328
15

The NLRP3 inflammasome: molecular activation and regulation to therapeutics.
Karen V Swanson, Meng Deng, Jenny P-Y Ting. Nat Rev Immunol 2019
15

Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
15

Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein.
Wei Wang, Linh T T Nguyen, Christopher Burlak, Fariba Chegini, Feng Guo, Tim Chataway, Shulin Ju, Oriana S Fisher, David W Miller, Debajyoti Datta,[...]. Proc Natl Acad Sci U S A 2016
131
15

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Rebecca C Coll, James R Hill, Christopher J Day, Alina Zamoshnikova, Dave Boucher, Nicholas L Massey, Jessica L Chitty, James A Fraser, Michael P Jennings, Avril A B Robertson,[...]. Nat Chem Biol 2019
265
14

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
14

The inflammasomes.
Kate Schroder, Jurg Tschopp. Cell 2010
14

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson's disease.
Yan Zhou, Ming Lu, Ren-Hong Du, Chen Qiao, Chun-Yi Jiang, Ke-Zhong Zhang, Jian-Hua Ding, Gang Hu. Mol Neurodegener 2016
237
13

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
Wei Zhang, Tongguang Wang, Zhong Pei, David S Miller, Xuefei Wu, Michelle L Block, Belinda Wilson, Wanqin Zhang, Yong Zhou, Jau-Shyong Hong,[...]. FASEB J 2005
813
13

The NLRP3 Inflammasome is Involved in the Pathogenesis of Parkinson's Disease in Rats.
Zhijuan Mao, Chanchan Liu, Suqiong Ji, Qingmei Yang, Hongxiang Ye, Haiyan Han, Zheng Xue. Neurochem Res 2017
76
17

Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.
Souvarish Sarkar, Emir Malovic, Dilshan S Harishchandra, Shivani Ghaisas, Nikhil Panicker, Adhithiya Charli, Bharathi N Palanisamy, Dharmin Rokad, Huajun Jin, Vellareddy Anantharam,[...]. NPJ Parkinsons Dis 2017
121
13

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease.
Alexander Gerhard, Nicola Pavese, Gary Hotton, Federico Turkheimer, Meltem Es, Alexander Hammers, Karla Eggert, Wolfgang Oertel, Richard B Banati, David J Brooks. Neurobiol Dis 2006
711
13

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
13

Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson's disease.
Zheng Fan, Yu-Ting Pan, Zhi-Yuan Zhang, Hui Yang, Shu-Yue Yu, Yan Zheng, Jing-Hong Ma, Xiao-Min Wang. J Neuroinflammation 2020
38
34

NLRP3 expression in mesencephalic neurons and characterization of a rare NLRP3 polymorphism associated with decreased risk of Parkinson's disease.
Katharine M von Herrmann, Lucas A Salas, Eileen M Martinez, Alison L Young, Joseph M Howard, Mary S Feldman, Brock C Christensen, Owen M Wilkins, Stephen L Lee, William F Hickey,[...]. NPJ Parkinsons Dis 2018
57
21


Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
Ilie-Cosmin Stancu, Niels Cremers, Hannah Vanrusselt, Julien Couturier, Alexandre Vanoosthuyse, Sofie Kessels, Chritica Lodder, Bert Brône, François Huaux, Jean-Noël Octave,[...]. Acta Neuropathol 2019
112
12

Targeting the NLRP3 inflammasome in inflammatory diseases.
Matthew S J Mangan, Edward J Olhava, William R Roush, H Martin Seidel, Gary D Glick, Eicke Latz. Nat Rev Drug Discov 2018
486
12

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia.
Lisa Fellner, Regina Irschick, Kathrin Schanda, Markus Reindl, Lars Klimaschewski, Werner Poewe, Gregor K Wenning, Nadia Stefanova. Glia 2013
377
12

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
11

Activation and regulation of the inflammasomes.
Eicke Latz, T Sam Xiao, Andrea Stutz. Nat Rev Immunol 2013
11

Parkinson disease.
Werner Poewe, Klaus Seppi, Caroline M Tanner, Glenda M Halliday, Patrik Brundin, Jens Volkmann, Anette-Eleonore Schrag, Anthony E Lang. Nat Rev Dis Primers 2017
11

Editor's Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice.
Eileen M Martinez, Alison L Young, Yash R Patankar, Brent L Berwin, Li Wang, Katharine M von Herrmann, Jaclyn M Weier, Matthew C Havrda. Toxicol Sci 2017
33
33


NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients.
Sonja Johann, Marius Heitzer, Mithila Kanagaratnam, Anand Goswami, Tania Rizo, Joachim Weis, Dirk Troost, Cordian Beyer. Glia 2015
123
10

Inflammasomes in neuroinflammatory and neurodegenerative diseases.
Sofie Voet, Sahana Srinivasan, Mohamed Lamkanfi, Geert van Loo. EMBO Mol Med 2019
210
10

Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C Hirsch, Stéphane Hunot. Lancet Neurol 2009
10


Innate immune activation in neurodegenerative disease.
Michael T Heneka, Markus P Kummer, Eicke Latz. Nat Rev Immunol 2014
749
10

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome.
Christine Juliana, Teresa Fernandes-Alnemri, Jianghong Wu, Pinaki Datta, Leobaldo Solorzano, Je-Wook Yu, Rong Meng, Andrew A Quong, Eicke Latz, Charles P Scott,[...]. J Biol Chem 2010
346
10

Mechanisms and functions of inflammasomes.
Mohamed Lamkanfi, Vishva M Dixit. Cell 2014
10

Inflammasome and α-synuclein in Parkinson's disease: A cross-sectional study.
Koustav Chatterjee, Akash Roy, Rebecca Banerjee, Supriyo Choudhury, Banashree Mondal, Saptak Halder, Purba Basu, Shantanu Shubham, Sanjit Dey, Hrishikesh Kumar. J Neuroimmunol 2020
30
33

Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease.
Md Ezazul Haque, Mahbuba Akther, Md Jakaria, In-Su Kim, Shofiul Azam, Dong-Kug Choi. Mov Disord 2020
71
12

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.
Leslie Freeman, Haitao Guo, Clément N David, W June Brickey, Sushmita Jha, Jenny P-Y Ting. J Exp Med 2017
164
9

The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins.
Vandana Deora, John D Lee, Eduardo A Albornoz, Luke McAlary, Cyril J Jagaraj, Avril A B Robertson, Julie D Atkin, Matthew A Cooper, Kate Schroder, Justin J Yerbury,[...]. Glia 2020
63
14

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease.
Shuo Wang, Yu-He Yuan, Nai-Hong Chen, Hong-Bo Wang. Int Immunopharmacol 2019
144
9

Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease.
Xiaojuan Han, Sifan Sun, Yiming Sun, Qiqi Song, Jialei Zhu, Nanshan Song, Miaomiao Chen, Ting Sun, Meiling Xia, Jianhua Ding,[...]. Autophagy 2019
102
9

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Insup Choi, Yuanxi Zhang, Steven P Seegobin, Mathilde Pruvost, Qian Wang, Kerry Purtell, Bin Zhang, Zhenyu Yue. Nat Commun 2020
105
9

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.
Vanessa Brochard, Béhazine Combadière, Annick Prigent, Yasmina Laouar, Aline Perrin, Virginie Beray-Berthat, Olivia Bonduelle, Daniel Alvarez-Fischer, Jacques Callebert, Jean-Marie Launay,[...]. J Clin Invest 2009
672
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.