Keiji Okamoto, Hiroyuki Seimiya. Cells 2019
Times Cited: 34
Times Cited: 34
Times Cited
Times Co-cited
Similarity
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
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Systematic analysis of telomere length and somatic alterations in 31 cancer types.
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Alternative lengthening of telomeres: models, mechanisms and implications.
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Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
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Telomeres in cancer: tumour suppression and genome instability.
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
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TERT promoter mutations in familial and sporadic melanoma.
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Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
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Emerging roles of telomeric chromatin alterations in cancer.
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo. J Exp Clin Cancer Res 2019
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Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
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Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
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Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
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The RNA component of human telomerase.
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Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
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Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo.
Kyotaro Hirashima, Hiroyuki Seimiya. Nucleic Acids Res 2015
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Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Jian Hu, Soyoon Sarah Hwang, Marc Liesa, Boyi Gan, Ergun Sahin, Mariela Jaskelioff, Zhihu Ding, Haoqiang Ying, Adam T Boutin, Hailei Zhang,[...]. Cell 2012
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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
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Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
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Replicating through telomeres: a means to an end.
Paula Martínez, Maria A Blasco. Trends Biochem Sci 2015
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Shelterin: the protein complex that shapes and safeguards human telomeres.
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Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
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Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
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Telomerase activity in human germline and embryonic tissues and cells.
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Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors.
A Prasanth Saraswati, Nicola Relitti, Margherita Brindisi, Sandra Gemma, Daniela Zisterer, Stefania Butini, Giuseppe Campiani. Drug Discov Today 2019
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Extension of life-span by introduction of telomerase into normal human cells.
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8
G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells.
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
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Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.
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Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
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G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
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Telomere length influences cancer cell differentiation in vivo.
Kyotaro Hirashima, Toshiro Migita, Shigeo Sato, Yukiko Muramatsu, Yuichi Ishikawa, Hiroyuki Seimiya. Mol Cell Biol 2013
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Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-Ya, Ichiro Nakano, Kazuo Nagasawa,[...]. Sci Rep 2017
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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide. Oncogene 2006
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Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, Takashi Tsuruo. Cancer Cell 2005
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A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
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Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Frédérique Magdinier, Guido Stadler, Kathyrin R Wagner, Jerry W Shay, Woodring E Wright. Genes Dev 2014
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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
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Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.