Keiji Okamoto, Hiroyuki Seimiya. Cells 2019
Times Cited: 40
Times Cited: 40
Times Cited
Times Co-cited
Similarity
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
27
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
22
Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
20
Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
20
12
12
Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo.
Kyotaro Hirashima, Hiroyuki Seimiya. Nucleic Acids Res 2015
Kyotaro Hirashima, Hiroyuki Seimiya. Nucleic Acids Res 2015
12
Telomeres in cancer: tumour suppression and genome instability.
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
10
TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
10
Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
10
Emerging roles of telomeric chromatin alterations in cancer.
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo. J Exp Clin Cancer Res 2019
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo. J Exp Clin Cancer Res 2019
25
10
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
10
Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
10
Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
10
The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
10
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
10
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
10
G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells.
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
19
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.
D Sen, W Gilbert. Nature 1988
D Sen, W Gilbert. Nature 1988
10
Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
Takeshi Miyazaki, Yang Pan, Kaushal Joshi, Deepti Purohit, Bin Hu, Habibe Demir, Sarmistha Mazumder, Sachiko Okabe, Takao Yamori, Mariano Viapiano,[...]. Clin Cancer Res 2012
Takeshi Miyazaki, Yang Pan, Kaushal Joshi, Deepti Purohit, Bin Hu, Habibe Demir, Sarmistha Mazumder, Sachiko Okabe, Takao Yamori, Mariano Viapiano,[...]. Clin Cancer Res 2012
10
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
10
Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-Ya, Ichiro Nakano, Kazuo Nagasawa,[...]. Sci Rep 2017
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-Ya, Ichiro Nakano, Kazuo Nagasawa,[...]. Sci Rep 2017
19
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide. Oncogene 2006
H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide. Oncogene 2006
10
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, Takashi Tsuruo. Cancer Cell 2005
Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, Takashi Tsuruo. Cancer Cell 2005
10
A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
10
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Jian Hu, Soyoon Sarah Hwang, Marc Liesa, Boyi Gan, Ergun Sahin, Mariela Jaskelioff, Zhihu Ding, Haoqiang Ying, Adam T Boutin, Hailei Zhang,[...]. Cell 2012
Jian Hu, Soyoon Sarah Hwang, Marc Liesa, Boyi Gan, Ergun Sahin, Mariela Jaskelioff, Zhihu Ding, Haoqiang Ying, Adam T Boutin, Hailei Zhang,[...]. Cell 2012
7
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
7
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
7
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
7
Accelerated telomere shortening in response to life stress.
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
Elissa S Epel, Elizabeth H Blackburn, Jue Lin, Firdaus S Dhabhar, Nancy E Adler, Jason D Morrow, Richard M Cawthon. Proc Natl Acad Sci U S A 2004
7
Replicating through telomeres: a means to an end.
Paula Martínez, Maria A Blasco. Trends Biochem Sci 2015
Paula Martínez, Maria A Blasco. Trends Biochem Sci 2015
7
TERT promoter mutations in telomere biology.
Barbara Heidenreich, Rajiv Kumar. Mutat Res Rev Mutat Res 2017
Barbara Heidenreich, Rajiv Kumar. Mutat Res Rev Mutat Res 2017
7
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
7
Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
7
Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
7
Raising the bar in anticancer therapy: recent advances in, and perspectives on, telomerase inhibitors.
A Prasanth Saraswati, Nicola Relitti, Margherita Brindisi, Sandra Gemma, Daniela Zisterer, Stefania Butini, Giuseppe Campiani. Drug Discov Today 2019
A Prasanth Saraswati, Nicola Relitti, Margherita Brindisi, Sandra Gemma, Daniela Zisterer, Stefania Butini, Giuseppe Campiani. Drug Discov Today 2019
18
Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.
Fukiko Kawai-Kitahata, Yasuhiro Asahina, Shinji Tanaka, Sei Kakinuma, Miyako Murakawa, Sayuri Nitta, Takako Watanabe, Satoshi Otani, Miki Taniguchi, Fumio Goto,[...]. J Gastroenterol 2016
Fukiko Kawai-Kitahata, Yasuhiro Asahina, Shinji Tanaka, Sei Kakinuma, Miyako Murakawa, Sayuri Nitta, Takako Watanabe, Satoshi Otani, Miki Taniguchi, Fumio Goto,[...]. J Gastroenterol 2016
7
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
7
Understanding TERT Promoter Mutations: A Common Path to Immortality.
Robert J A Bell, H Tomas Rube, Ana Xavier-Magalhães, Bruno M Costa, Andrew Mancini, Jun S Song, Joseph F Costello. Mol Cancer Res 2016
Robert J A Bell, H Tomas Rube, Ana Xavier-Magalhães, Bruno M Costa, Andrew Mancini, Jun S Song, Joseph F Costello. Mol Cancer Res 2016
7
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
7
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.
Jay E Johnson, Kajia Cao, Paul Ryvkin, Li-San Wang, F Brad Johnson. Nucleic Acids Res 2010
Jay E Johnson, Kajia Cao, Paul Ryvkin, Li-San Wang, F Brad Johnson. Nucleic Acids Res 2010
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.