Keiji Okamoto, Hiroyuki Seimiya. Cells 2019
Times Cited: 54
Times Cited: 54
Times Cited
Times Co-cited
Similarity
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
24
Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
20
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
16
Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
16
14
14
12
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
12
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
12
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
12
11
Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
11
Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
Kunitoshi Chiba, Franziska K Lorbeer, A Hunter Shain, David T McSwiggen, Eva Schruf, Areum Oh, Jekwan Ryu, Xavier Darzacq, Boris C Bastian, Dirk Hockemeyer. Science 2017
11
The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
11
Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
9
TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
9
9
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
Elizabeth H Blackburn, Elissa S Epel, Jue Lin. Science 2015
9
Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation.
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
Semih Can Akıncılar, Ekta Khattar, Priscilla Li Shan Boon, Bilal Unal, Melissa Jane Fullwood, Vinay Tergaonkar. Cancer Discov 2016
9
Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
9
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
9
Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo.
Kyotaro Hirashima, Hiroyuki Seimiya. Nucleic Acids Res 2015
Kyotaro Hirashima, Hiroyuki Seimiya. Nucleic Acids Res 2015
11
Telomeres in cancer: tumour suppression and genome instability.
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
7
Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
Yinghui Li, Vinay Tergaonkar. Cancer Res 2014
7
Emerging roles of telomeric chromatin alterations in cancer.
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo. J Exp Clin Cancer Res 2019
Stefano Cacchione, Annamaria Biroccio, Angela Rizzo. J Exp Clin Cancer Res 2019
20
Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD).
Wanil Kim, Jerry W Shay. Differentiation 2018
Wanil Kim, Jerry W Shay. Differentiation 2018
13
TERT promoter mutations in telomere biology.
Barbara Heidenreich, Rajiv Kumar. Mutat Res Rev Mutat Res 2017
Barbara Heidenreich, Rajiv Kumar. Mutat Res Rev Mutat Res 2017
7
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
7
7
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
7
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
7
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players.
Xiaotian Yuan, Catharina Larsson, Dawei Xu. Oncogene 2019
Xiaotian Yuan, Catharina Larsson, Dawei Xu. Oncogene 2019
7
Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
7
G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells.
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
Daiki Hasegawa, Sachiko Okabe, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Hiroyuki Seimiya. Biochem Biophys Res Commun 2016
17
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.
D Sen, W Gilbert. Nature 1988
D Sen, W Gilbert. Nature 1988
7
Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
Takeshi Miyazaki, Yang Pan, Kaushal Joshi, Deepti Purohit, Bin Hu, Habibe Demir, Sarmistha Mazumder, Sachiko Okabe, Takao Yamori, Mariano Viapiano,[...]. Clin Cancer Res 2012
Takeshi Miyazaki, Yang Pan, Kaushal Joshi, Deepti Purohit, Bin Hu, Habibe Demir, Sarmistha Mazumder, Sachiko Okabe, Takao Yamori, Mariano Viapiano,[...]. Clin Cancer Res 2012
7
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
7
Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-Ya, Ichiro Nakano, Kazuo Nagasawa,[...]. Sci Rep 2017
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-Ya, Ichiro Nakano, Kazuo Nagasawa,[...]. Sci Rep 2017
14
G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide. Oncogene 2006
H Tahara, K Shin-Ya, H Seimiya, H Yamada, T Tsuruo, T Ide. Oncogene 2006
7
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.
Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, Takashi Tsuruo. Cancer Cell 2005
Hiroyuki Seimiya, Yukiko Muramatsu, Tomokazu Ohishi, Takashi Tsuruo. Cancer Cell 2005
7
A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
A A Chiappori, T Kolevska, D R Spigel, S Hager, M Rarick, S Gadgeel, N Blais, J Von Pawel, L Hart, M Reck,[...]. Ann Oncol 2015
7
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.
Wanil Kim, Andrew T Ludlow, Jaewon Min, Jerome D Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E Wright, Jerry W Shay. PLoS Biol 2016
Wanil Kim, Andrew T Ludlow, Jaewon Min, Jerome D Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E Wright, Jerry W Shay. PLoS Biol 2016
7
7
Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Frédérique Magdinier, Guido Stadler, Kathyrin R Wagner, Jerry W Shay, Woodring E Wright. Genes Dev 2014
Jérôme D Robin, Andrew T Ludlow, Kimberly Batten, Frédérique Magdinier, Guido Stadler, Kathyrin R Wagner, Jerry W Shay, Woodring E Wright. Genes Dev 2014
7
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.