Yang Yang, Huanan Wang, Mohammed Kouadir, Houhui Song, Fushan Shi. Cell Death Dis 2019
Times Cited: 458
Times Cited: 458
Times Cited
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Similarity
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Nathan Kelley, Devon Jeltema, Yanhui Duan, Yuan He. Int J Mol Sci 2019
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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A role for mitochondria in NLRP3 inflammasome activation.
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Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
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K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
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NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
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Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
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Critical role for calcium mobilization in activation of the NLRP3 inflammasome.
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
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Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
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Non-canonical inflammasome activation targets caspase-11.
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MCC950 closes the active conformation of NLRP3 to an inactive state.
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Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.
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Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
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The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
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Inflammatory caspases are innate immune receptors for intracellular LPS.
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The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance.
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
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Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death.
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
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Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 Inflammasome.
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NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
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Focus on the Role of NLRP3 Inflammasome in Diseases.
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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation.
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OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.