James B Wing, Atsushi Tanaka, Shimon Sakaguchi. Immunity 2019
Times Cited: 219
Times Cited: 219
Times Cited
Times Co-cited
Similarity
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.
Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, Tomoko Shima, Kajsa Wing, Akira Niwa, Christophe Parizot, Cécile Taflin, Toshio Heike, Dominique Valeyre,[...]. Immunity 2009
Makoto Miyara, Yumiko Yoshioka, Akihiko Kitoh, Tomoko Shima, Kajsa Wing, Akira Niwa, Christophe Parizot, Cécile Taflin, Toshio Heike, Dominique Valeyre,[...]. Immunity 2009
17
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.
S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda. J Immunol 1995
S Sakaguchi, N Sakaguchi, M Asano, M Itoh, M Toda. J Immunol 1995
13
Regulatory T cells: mechanisms of differentiation and function.
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
Steven Z Josefowicz, Li-Fan Lu, Alexander Y Rudensky. Annu Rev Immunol 2012
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Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
10
Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.
George Plitas, Catherine Konopacki, Kenmin Wu, Paula D Bos, Monica Morrow, Ekaterina V Putintseva, Dmitriy M Chudakov, Alexander Y Rudensky. Immunity 2016
George Plitas, Catherine Konopacki, Kenmin Wu, Paula D Bos, Monica Morrow, Ekaterina V Putintseva, Dmitriy M Chudakov, Alexander Y Rudensky. Immunity 2016
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Regulatory T cells and immune tolerance.
Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura, Masahiro Ono. Cell 2008
Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura, Masahiro Ono. Cell 2008
9
Regulatory T cells in cancer immunosuppression - implications for anticancer therapy.
Yosuke Togashi, Kohei Shitara, Hiroyoshi Nishikawa. Nat Rev Clin Oncol 2019
Yosuke Togashi, Kohei Shitara, Hiroyoshi Nishikawa. Nat Rev Clin Oncol 2019
9
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
Jason D Fontenot, Marc A Gavin, Alexander Y Rudensky. Nat Immunol 2003
9
Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.
Takuro Saito, Hiroyoshi Nishikawa, Hisashi Wada, Yuji Nagano, Daisuke Sugiyama, Koji Atarashi, Yuka Maeda, Masahide Hamaguchi, Naganari Ohkura, Eiichi Sato,[...]. Nat Med 2016
Takuro Saito, Hiroyoshi Nishikawa, Hisashi Wada, Yuji Nagano, Daisuke Sugiyama, Koji Atarashi, Yuka Maeda, Masahide Hamaguchi, Naganari Ohkura, Eiichi Sato,[...]. Nat Med 2016
8
Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
Marco De Simone, Alberto Arrigoni, Grazisa Rossetti, Paola Gruarin, Valeria Ranzani, Claudia Politano, Raoul J P Bonnal, Elena Provasi, Maria Lucia Sarnicola, Ilaria Panzeri,[...]. Immunity 2016
Marco De Simone, Alberto Arrigoni, Grazisa Rossetti, Paola Gruarin, Valeria Ranzani, Claudia Politano, Raoul J P Bonnal, Elena Provasi, Maria Lucia Sarnicola, Ilaria Panzeri,[...]. Immunity 2016
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Regulatory T Cells and Human Disease.
Shimon Sakaguchi, Norihisa Mikami, James B Wing, Atsushi Tanaka, Kenji Ichiyama, Naganari Ohkura. Annu Rev Immunol 2020
Shimon Sakaguchi, Norihisa Mikami, James B Wing, Atsushi Tanaka, Kenji Ichiyama, Naganari Ohkura. Annu Rev Immunol 2020
7
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Ricardo J Miragaia, Tomás Gomes, Agnieszka Chomka, Laura Jardine, Angela Riedel, Ahmed N Hegazy, Natasha Whibley, Andrea Tucci, Xi Chen, Ida Lindeman,[...]. Immunity 2019
Ricardo J Miragaia, Tomás Gomes, Agnieszka Chomka, Laura Jardine, Angela Riedel, Ahmed N Hegazy, Natasha Whibley, Andrea Tucci, Xi Chen, Ida Lindeman,[...]. Immunity 2019
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FOXP3+ regulatory T cells in the human immune system.
Shimon Sakaguchi, Makoto Miyara, Cristina M Costantino, David A Hafler. Nat Rev Immunol 2010
Shimon Sakaguchi, Makoto Miyara, Cristina M Costantino, David A Hafler. Nat Rev Immunol 2010
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Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis.
Bin Shang, Yao Liu, Shu-juan Jiang, Yi Liu. Sci Rep 2015
Bin Shang, Yao Liu, Shu-juan Jiang, Yi Liu. Sci Rep 2015
6
Regulatory T cells in autoimmune disease.
Margarita Dominguez-Villar, David A Hafler. Nat Immunol 2018
Margarita Dominguez-Villar, David A Hafler. Nat Immunol 2018
6
Regulatory T Cells: Differentiation and Function.
George Plitas, Alexander Y Rudensky. Cancer Immunol Res 2016
George Plitas, Alexander Y Rudensky. Cancer Immunol Res 2016
6
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice.
Jeong M Kim, Jeffrey P Rasmussen, Alexander Y Rudensky. Nat Immunol 2007
Jeong M Kim, Jeffrey P Rasmussen, Alexander Y Rudensky. Nat Immunol 2007
6
6
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
6
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.
Daisuke Sugiyama, Hiroyoshi Nishikawa, Yuka Maeda, Megumi Nishioka, Atsushi Tanemura, Ichiro Katayama, Sachiko Ezoe, Yuzuru Kanakura, Eiichi Sato, Yasuo Fukumori,[...]. Proc Natl Acad Sci U S A 2013
Daisuke Sugiyama, Hiroyoshi Nishikawa, Yuka Maeda, Megumi Nishioka, Atsushi Tanemura, Ichiro Katayama, Sachiko Ezoe, Yuzuru Kanakura, Eiichi Sato, Yasuo Fukumori,[...]. Proc Natl Acad Sci U S A 2013
5
Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.
Chunhong Zheng, Liangtao Zheng, Jae-Kwang Yoo, Huahu Guo, Yuanyuan Zhang, Xinyi Guo, Boxi Kang, Ruozhen Hu, Julie Y Huang, Qiming Zhang,[...]. Cell 2017
Chunhong Zheng, Liangtao Zheng, Jae-Kwang Yoo, Huahu Guo, Yuanyuan Zhang, Xinyi Guo, Boxi Kang, Ruozhen Hu, Julie Y Huang, Qiming Zhang,[...]. Cell 2017
5
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells.
Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E Shoelson, Christophe Benoist, Diane Mathis. Nature 2012
Daniela Cipolletta, Markus Feuerer, Amy Li, Nozomu Kamei, Jongsoon Lee, Steven E Shoelson, Christophe Benoist, Diane Mathis. Nature 2012
5
Immunometabolism of regulatory T cells.
Ryan Newton, Bhavana Priyadharshini, Laurence A Turka. Nat Immunol 2016
Ryan Newton, Bhavana Priyadharshini, Laurence A Turka. Nat Immunol 2016
5
Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism.
Clarissa Campbell, Alexander Rudensky. Cell Metab 2020
Clarissa Campbell, Alexander Rudensky. Cell Metab 2020
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An essential role for Scurfin in CD4+CD25+ T regulatory cells.
Roli Khattri, Tom Cox, Sue-Ann Yasayko, Fred Ramsdell. Nat Immunol 2003
Roli Khattri, Tom Cox, Sue-Ann Yasayko, Fred Ramsdell. Nat Immunol 2003
5
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.
M E Brunkow, E W Jeffery, K A Hjerrild, B Paeper, L B Clark, S A Yasayko, J E Wilkinson, D Galas, S F Ziegler, F Ramsdell. Nat Genet 2001
M E Brunkow, E W Jeffery, K A Hjerrild, B Paeper, L B Clark, S A Yasayko, J E Wilkinson, D Galas, S F Ziegler, F Ramsdell. Nat Genet 2001
5
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.
Yuri P Rubtsov, Jeffrey P Rasmussen, Emil Y Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R Henderson,[...]. Immunity 2008
Yuri P Rubtsov, Jeffrey P Rasmussen, Emil Y Chi, Jason Fontenot, Luca Castelli, Xin Ye, Piper Treuting, Lisa Siewe, Axel Roers, William R Henderson,[...]. Immunity 2008
5
Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer.
Paul Salama, Michael Phillips, Fabienne Grieu, Melinda Morris, Nik Zeps, David Joseph, Cameron Platell, Barry Iacopetta. J Clin Oncol 2009
Paul Salama, Michael Phillips, Fabienne Grieu, Melinda Morris, Nik Zeps, David Joseph, Cameron Platell, Barry Iacopetta. J Clin Oncol 2009
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Fundamental Mechanisms of Immune Checkpoint Blockade Therapy.
Spencer C Wei, Colm R Duffy, James P Allison. Cancer Discov 2018
Spencer C Wei, Colm R Duffy, James P Allison. Cancer Discov 2018
5
PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer.
Takahiro Kamada, Yosuke Togashi, Christopher Tay, Danbee Ha, Akinori Sasaki, Yoshiaki Nakamura, Eiichi Sato, Shota Fukuoka, Yasuko Tada, Atsushi Tanaka,[...]. Proc Natl Acad Sci U S A 2019
Takahiro Kamada, Yosuke Togashi, Christopher Tay, Danbee Ha, Akinori Sasaki, Yoshiaki Nakamura, Eiichi Sato, Shota Fukuoka, Yasuko Tada, Atsushi Tanaka,[...]. Proc Natl Acad Sci U S A 2019
5
CTLA-4 control over Foxp3+ regulatory T cell function.
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin, Tomoyuki Yamaguchi, Makoto Miyara, Zoltan Fehervari, Takashi Nomura, Shimon Sakaguchi. Science 2008
5
Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification.
Robert M Samstein, Aaron Arvey, Steven Z Josefowicz, Xiao Peng, Alex Reynolds, Richard Sandstrom, Shane Neph, Peter Sabo, Jeong M Kim, Will Liao,[...]. Cell 2012
Robert M Samstein, Aaron Arvey, Steven Z Josefowicz, Xiao Peng, Alex Reynolds, Richard Sandstrom, Shane Neph, Peter Sabo, Jeong M Kim, Will Liao,[...]. Cell 2012
5
Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR.
David Zemmour, Rapolas Zilionis, Evgeny Kiner, Allon M Klein, Diane Mathis, Christophe Benoist. Nat Immunol 2018
David Zemmour, Rapolas Zilionis, Evgeny Kiner, Allon M Klein, Diane Mathis, Christophe Benoist. Nat Immunol 2018
5
CCR8+FOXp3+ Treg cells as master drivers of immune regulation.
Yiftah Barsheshet, Gizi Wildbaum, Eran Levy, Alon Vitenshtein, Chika Akinseye, Jeremy Griggs, Sergio A Lira, Nathan Karin. Proc Natl Acad Sci U S A 2017
Yiftah Barsheshet, Gizi Wildbaum, Eran Levy, Alon Vitenshtein, Chika Akinseye, Jeremy Griggs, Sergio A Lira, Nathan Karin. Proc Natl Acad Sci U S A 2017
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Understanding the tumor immune microenvironment (TIME) for effective therapy.
Mikhail Binnewies, Edward W Roberts, Kelly Kersten, Vincent Chan, Douglas F Fearon, Miriam Merad, Lisa M Coussens, Dmitry I Gabrilovich, Suzanne Ostrand-Rosenberg, Catherine C Hedrick,[...]. Nat Med 2018
Mikhail Binnewies, Edward W Roberts, Kelly Kersten, Vincent Chan, Douglas F Fearon, Miriam Merad, Lisa M Coussens, Dmitry I Gabrilovich, Suzanne Ostrand-Rosenberg, Catherine C Hedrick,[...]. Nat Med 2018
5
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.
Weihong Liu, Amy L Putnam, Zhou Xu-Yu, Gregory L Szot, Michael R Lee, Shirley Zhu, Peter A Gottlieb, Philipp Kapranov, Thomas R Gingeras, Barbara Fazekas de St Groth,[...]. J Exp Med 2006
Weihong Liu, Amy L Putnam, Zhou Xu-Yu, Gregory L Szot, Michael R Lee, Shirley Zhu, Peter A Gottlieb, Philipp Kapranov, Thomas R Gingeras, Barbara Fazekas de St Groth,[...]. J Exp Med 2006
5
Targeting CCR8 Induces Protective Antitumor Immunity and Enhances Vaccine-Induced Responses in Colon Cancer.
Daniel O Villarreal, Andrew L'Huillier, Susan Armington, Cristina Mottershead, Elena V Filippova, Brandon D Coder, Robert G Petit, Michael F Princiotta. Cancer Res 2018
Daniel O Villarreal, Andrew L'Huillier, Susan Armington, Cristina Mottershead, Elena V Filippova, Brandon D Coder, Robert G Petit, Michael F Princiotta. Cancer Res 2018
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Treg cell-based therapies: challenges and perspectives.
Caroline Raffin, Linda T Vo, Jeffrey A Bluestone. Nat Rev Immunol 2020
Caroline Raffin, Linda T Vo, Jeffrey A Bluestone. Nat Rev Immunol 2020
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The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature.
Ronald J deLeeuw, Sara E Kost, Juzer A Kakal, Brad H Nelson. Clin Cancer Res 2012
Ronald J deLeeuw, Sara E Kost, Juzer A Kakal, Brad H Nelson. Clin Cancer Res 2012
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Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.
Stefani Spranger, Daisy Dai, Brendan Horton, Thomas F Gajewski. Cancer Cell 2017
Stefani Spranger, Daisy Dai, Brendan Horton, Thomas F Gajewski. Cancer Cell 2017
4
Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.
David Wang, Jason Quiros, Kelly Mahuron, Chien-Chun Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani,[...]. Cell Rep 2018
David Wang, Jason Quiros, Kelly Mahuron, Chien-Chun Pai, Valeria Ranzani, Arabella Young, Stephanie Silveria, Tory Harwin, Arbi Abnousian, Massimiliano Pagani,[...]. Cell Rep 2018
4
4
Dendritic cells in cancer immunology and immunotherapy.
Stefanie K Wculek, Francisco J Cueto, Adriana M Mujal, Ignacio Melero, Matthew F Krummel, David Sancho. Nat Rev Immunol 2020
Stefanie K Wculek, Francisco J Cueto, Adriana M Mujal, Ignacio Melero, Matthew F Krummel, David Sancho. Nat Rev Immunol 2020
4
Next-generation regulatory T cell therapy.
Leonardo M R Ferreira, Yannick D Muller, Jeffrey A Bluestone, Qizhi Tang. Nat Rev Drug Discov 2019
Leonardo M R Ferreira, Yannick D Muller, Jeffrey A Bluestone, Qizhi Tang. Nat Rev Drug Discov 2019
4
The alarmin IL-33 promotes regulatory T-cell function in the intestine.
Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N Hegazy,[...]. Nature 2014
Chris Schiering, Thomas Krausgruber, Agnieszka Chomka, Anja Fröhlich, Krista Adelmann, Elizabeth A Wohlfert, Johanna Pott, Thibault Griseri, Julia Bollrath, Ahmed N Hegazy,[...]. Nature 2014
4
Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells.
Aaron Arvey, Joris van der Veeken, Robert M Samstein, Yongqiang Feng, John A Stamatoyannopoulos, Alexander Y Rudensky. Nat Immunol 2014
Aaron Arvey, Joris van der Veeken, Robert M Samstein, Yongqiang Feng, John A Stamatoyannopoulos, Alexander Y Rudensky. Nat Immunol 2014
4
Foxp3+ follicular regulatory T cells control the germinal center response.
Michelle A Linterman, Wim Pierson, Sau K Lee, Axel Kallies, Shimpei Kawamoto, Tim F Rayner, Monika Srivastava, Devina P Divekar, Laura Beaton, Jennifer J Hogan,[...]. Nat Med 2011
Michelle A Linterman, Wim Pierson, Sau K Lee, Axel Kallies, Shimpei Kawamoto, Tim F Rayner, Monika Srivastava, Devina P Divekar, Laura Beaton, Jennifer J Hogan,[...]. Nat Med 2011
4
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