A citation-based method for searching scientific literature

Tareq Saleh, Liliya Tyutyunyk-Massey, David A Gewirtz. Cancer Res 2019
Times Cited: 53







List of co-cited articles
939 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Senescence-associated reprogramming promotes cancer stemness.
Maja Milanovic, Dorothy N Y Fan, Dimitri Belenki, J Henry M Däbritz, Zhen Zhao, Yong Yu, Jan R Dörr, Lora Dimitrova, Dido Lenze, Ines A Monteiro Barbosa,[...]. Nature 2018
288
67

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Marco Demaria, Monique N O'Leary, Jianhui Chang, Lijian Shao, Su Liu, Fatouma Alimirah, Kristin Koenig, Catherine Le, Natalia Mitin, Allison M Deal,[...]. Cancer Discov 2017
386
56

Cellular Senescence: Defining a Path Forward.
Vassilis Gorgoulis, Peter D Adams, Andrea Alimonti, Dorothy C Bennett, Oliver Bischof, Cleo Bishop, Judith Campisi, Manuel Collado, Konstantinos Evangelou, Gerardo Ferbeyre,[...]. Cell 2019
350
49

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
704
43

Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.
Rachel S Roberson, Steven J Kussick, Eric Vallieres, Szu-Yu J Chen, Daniel Y Wu. Cancer Res 2005
223
41

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Reut Yosef, Noam Pilpel, Ronit Tokarsky-Amiel, Anat Biran, Yossi Ovadya, Snir Cohen, Ezra Vadai, Liat Dassa, Elisheva Shahar, Reba Condiotti,[...]. Nat Commun 2016
320
41

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
667
41

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
39

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
39

Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
426
37


An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
703
35

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
33

Therapy-induced senescence in cancer.
Jonathan A Ewald, Joshua A Desotelle, George Wilding, David F Jarrard. J Natl Cancer Inst 2010
413
33

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
33

Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence.
Hubert Fleury, Nicolas Malaquin, Véronique Tu, Sophie Gilbert, Aurélie Martinez, Marc-Alexandre Olivier, Alexandre Sauriol, Laudine Communal, Kim Leclerc-Desaulniers, Euridice Carmona,[...]. Nat Commun 2019
47
38

Therapy-Induced Senescence: An "Old" Friend Becomes the Enemy.
Tareq Saleh, Sarah Bloukh, Valerie J Carpenter, Enas Alwohoush, Jomana Bakeer, Sarah Darwish, Belal Azab, David A Gewirtz. Cancers (Basel) 2020
48
37

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
804
32

Tumor cell escape from therapy-induced senescence.
Tareq Saleh, Liliya Tyutyunyk-Massey, Graeme F Murray, Moureq R Alotaibi, Ajinkya S Kawale, Zeinab Elsayed, Scott C Henderson, Vasily Yakovlev, Lynne W Elmore, Amir Toor,[...]. Biochem Pharmacol 2019
29
55

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Marjolein P Baar, Renata M C Brandt, Diana A Putavet, Julian D D Klein, Kasper W J Derks, Benjamin R M Bourgeois, Sarah Stryeck, Yvonne Rijksen, Hester van Willigenburg, Danny A Feijtel,[...]. Cell 2017
500
30

Unmasking Transcriptional Heterogeneity in Senescent Cells.
Alejandra Hernandez-Segura, Tristan V de Jong, Simon Melov, Victor Guryev, Judith Campisi, Marco Demaria. Curr Biol 2017
193
30

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
30

The dynamic nature of senescence in cancer.
Soyoung Lee, Clemens A Schmitt. Nat Cell Biol 2019
153
28

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
28

Programmed cell senescence during mammalian embryonic development.
Daniel Muñoz-Espín, Marta Cañamero, Antonio Maraver, Gonzalo Gómez-López, Julio Contreras, Silvia Murillo-Cuesta, Alfonso Rodríguez-Baeza, Isabel Varela-Nieto, Jesús Ruberte, Manuel Collado,[...]. Cell 2013
626
28

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Jan R Dörr, Yong Yu, Maja Milanovic, Gregor Beuster, Christin Zasada, J Henry M Däbritz, Jan Lisec, Dido Lenze, Anne Gerhardt, Katharina Schleicher,[...]. Nature 2013
283
28

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
28

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
504
26

Reversal of human cellular senescence: roles of the p53 and p16 pathways.
Christian M Beauséjour, Ana Krtolica, Francesco Galimi, Masashi Narita, Scott W Lowe, Paul Yaswen, Judith Campisi. EMBO J 2003
827
26

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
Yi Zhu, Tamara Tchkonia, Heike Fuhrmann-Stroissnigg, Haiming M Dai, Yuanyuan Y Ling, Michael B Stout, Tamar Pirtskhalava, Nino Giorgadze, Kurt O Johnson, Cory B Giles,[...]. Aging Cell 2016
323
26

Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Cun Wang, Serena Vegna, Haojie Jin, Bente Benedict, Cor Lieftink, Christel Ramirez, Rodrigo Leite de Oliveira, Ben Morris, Jules Gadiot, Wei Wang,[...]. Nature 2019
78
26

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.
Birgit Ritschka, Mekayla Storer, Alba Mas, Florian Heinzmann, Mari Carmen Ortells, Jennifer P Morton, Owen J Sansom, Lars Zender, William M Keyes. Genes Dev 2017
229
26

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
205
26

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Tae-Won Kang, Tetyana Yevsa, Norman Woller, Lisa Hoenicke, Torsten Wuestefeld, Daniel Dauch, Anja Hohmeyer, Marcus Gereke, Ramona Rudalska, Anna Potapova,[...]. Nature 2011
745
26

A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC.
Leleesha Samaraweera, Alfred Adomako, Alicia Rodriguez-Gabin, Hayley M McDaid. Sci Rep 2017
61
26

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.
Robert H te Poele, Andrei L Okorokov, Lesley Jardine, Jeffrey Cummings, Simon P Joel. Cancer Res 2002
459
24

Identification of HSP90 inhibitors as a novel class of senolytics.
Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J McGowan, Yi Zhu, Robert W Brooks, Diego Grassi, Siobhan Q Gregg, Jennifer L Stripay, Akaitz Dorronsoro,[...]. Nat Commun 2017
212
24

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
24

Identification and characterization of Cardiac Glycosides as senolytic compounds.
Francisco Triana-Martínez, Pilar Picallos-Rabina, Sabela Da Silva-Álvarez, Federico Pietrocola, Susana Llanos, Verónica Rodilla, Enrica Soprano, Pablo Pedrosa, Alba Ferreirós, Marta Barradas,[...]. Nat Commun 2019
75
24

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
Masashi Narita, Sabrina Nũnez, Edith Heard, Masako Narita, Athena W Lin, Stephen A Hearn, David L Spector, Gregory J Hannon, Scott W Lowe. Cell 2003
22

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463.
Yi Zhu, Ewald J Doornebal, Tamar Pirtskhalava, Nino Giorgadze, Mark Wentworth, Heike Fuhrmann-Stroissnigg, Laura J Niedernhofer, Paul D Robbins, Tamara Tchkonia, James L Kirkland. Aging (Albany NY) 2017
191
22

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C W Vredeveld, Sirith Douma, Remco van Doorn, Christophe J Desmet, Lucien A Aarden, Wolter J Mooi, Daniel S Peeper. Cell 2008
22

Two-Step Senescence-Focused Cancer Therapies.
Cynthia J Sieben, Ines Sturmlechner, Bart van de Sluis, Jan M van Deursen. Trends Cell Biol 2018
74
22

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Remi-Martin Laberge, Yu Sun, Arturo V Orjalo, Christopher K Patil, Adam Freund, Lili Zhou, Samuel C Curran, Albert R Davalos, Kathleen A Wilson-Edell, Su Liu,[...]. Nat Cell Biol 2015
461
22

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.
Branca I Pereira, Oliver P Devine, Milica Vukmanovic-Stejic, Emma S Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J Sebire, Veronica Kinsler, Alexis Valdovinos,[...]. Nat Commun 2019
89
22

Cardiac glycosides are broad-spectrum senolytics.
Ana Guerrero, Nicolás Herranz, Bin Sun, Verena Wagner, Suchira Gallage, Romain Guiho, Katharina Wolter, Joaquim Pombo, Elaine E Irvine, Andrew J Innes,[...]. Nat Metab 2019
66
22

High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
Liqin Wang, Rodrigo Leite de Oliveira, Cun Wang, João M Fernandes Neto, Sara Mainardi, Bastiaan Evers, Cor Lieftink, Ben Morris, Fleur Jochems, Lisa Willemsen,[...]. Cell Rep 2017
75
22

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
Jamie N Justice, Anoop M Nambiar, Tamar Tchkonia, Nathan K LeBrasseur, Rodolfo Pascual, Shahrukh K Hashmi, Larissa Prata, Michal M Masternak, Stephen B Kritchevsky, Nicolas Musi,[...]. EBioMedicine 2019
275
22

Chemokine signaling via the CXCR2 receptor reinforces senescence.
Juan C Acosta, Ana O'Loghlen, Ana Banito, Maria V Guijarro, Arnaud Augert, Selina Raguz, Marzia Fumagalli, Marco Da Costa, Celia Brown, Nikolay Popov,[...]. Cell 2008
977
22

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy.
Clemens A Schmitt, Jordan S Fridman, Meng Yang, Soyoung Lee, Eugene Baranov, Robert M Hoffman, Scott W Lowe. Cell 2002
753
22


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.