A citation-based method for searching scientific literature

Kirsten L Bryant, Clint A Stalnecker, Daniel Zeitouni, Jennifer E Klomp, Sen Peng, Andrey P Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M Waters, Samuel D George, Garima Tomar, Björn Papke, G Aaron Hobbs, Liang Yan, Tikvah K Hayes, J Nathaniel Diehl, Gennifer D Goode, Nina V Chaika, Yingxue Wang, Guo-Fang Zhang, Agnieszka K Witkiewicz, Erik S Knudsen, Emanuel F Petricoin, Pankaj K Singh, Jeffrey M Macdonald, Nhan L Tran, Costas A Lyssiotis, Haoqiang Ying, Alec C Kimmelman, Adrienne D Cox, Channing J Der. Nat Med 2019
Times Cited: 216







List of co-cited articles
1765 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap,[...]. Nat Med 2019
212
60

Pancreatic cancers require autophagy for tumor growth.
Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergun Sahin, Haoqiang Ying, Alexandra Bause, Yinghua Li, Jayne M Stommel, Giacomo Dell'antonio,[...]. Genes Dev 2011
872
30

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Keisuke Yamamoto, Anthony Venida, Julian Yano, Douglas E Biancur, Miwako Kakiuchi, Suprit Gupta, Albert S W Sohn, Subhadip Mukhopadhyay, Elaine Y Lin, Seth J Parker,[...]. Nature 2020
172
29

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Annan Yang, N V Rajeshkumar, Xiaoxu Wang, Shinichi Yabuuchi, Brian M Alexander, Gerald C Chu, Daniel D Von Hoff, Anirban Maitra, Alec C Kimmelman. Cancer Discov 2014
273
20

Targeting Autophagy in Cancer: Recent Advances and Future Directions.
Ravi K Amaravadi, Alec C Kimmelman, Jayanta Debnath. Cancer Discov 2019
189
19

Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms.
Annan Yang, Grit Herter-Sprie, Haikuo Zhang, Elaine Y Lin, Douglas Biancur, Xiaoxu Wang, Jiehui Deng, Josephine Hai, Shenghong Yang, Kwok-Kin Wong,[...]. Cancer Discov 2018
137
19

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
831
18

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.
Jude Canon, Karen Rex, Anne Y Saiki, Christopher Mohr, Keegan Cooke, Dhanashri Bagal, Kevin Gaida, Tyler Holt, Charles G Knutson, Neelima Koppada,[...]. Nature 2019
481
18

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
17

p53 status determines the role of autophagy in pancreatic tumour development.
Mathias T Rosenfeldt, Jim O'Prey, Jennifer P Morton, Colin Nixon, Gillian MacKay, Agata Mrowinska, Amy Au, Taranjit Singh Rai, Liang Zheng, Rachel Ridgway,[...]. Nature 2013
445
17

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
15

KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer.
Andrew M Waters, Channing J Der. Cold Spring Harb Perspect Med 2018
215
15

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
471
15

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
Talia Golan, Pascal Hammel, Michele Reni, Eric Van Cutsem, Teresa Macarulla, Michael J Hall, Joon-Oh Park, Daniel Hochhauser, Dirk Arnold, Do-Youn Oh,[...]. N Engl J Med 2019
573
15

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew, Jing Fan, Anne M Strohecker, Gizem Karsli-Uzunbas, Jurre J Kamphorst, Guanghua Chen, Johanna M S Lemons, Vassiliki Karantza,[...]. Genes Dev 2011
822
15

Genomic analyses identify molecular subtypes of pancreatic cancer.
Peter Bailey, David K Chang, Katia Nones, Amber L Johns, Ann-Marie Patch, Marie-Claude Gingras, David K Miller, Angelika N Christ, Tim J C Bruxner, Michael C Quinn,[...]. Nature 2016
15

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival.
Chih-Shia Lee, Liam C Lee, Tina L Yuan, Sirisha Chakka, Christof Fellmann, Scott W Lowe, Natasha J Caplen, Frank McCormick, Ji Luo. Proc Natl Acad Sci U S A 2019
50
28

Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial.
Thomas B Karasic, Mark H O'Hara, Arturo Loaiza-Bonilla, Kim A Reiss, Ursina R Teitelbaum, Erkut Borazanci, Ana De Jesus-Acosta, Colleen Redlinger, Jessica A Burrell, Daniel A Laheru,[...]. JAMA Oncol 2019
78
17

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
406
14

Targeting autophagy in cancer.
Jean M Mulcahy Levy, Christina G Towers, Andrew Thorburn. Nat Rev Cancer 2017
908
14


Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma.
Brian M Wolpin, Douglas A Rubinson, Xiaoxu Wang, Jennifer A Chan, James M Cleary, Peter C Enzinger, Charles S Fuchs, Nadine J McCleary, Jeffrey A Meyerhardt, Kimmie Ng,[...]. Oncologist 2014
178
14

Mechanism and medical implications of mammalian autophagy.
Ivan Dikic, Zvulun Elazar. Nat Rev Mol Cell Biol 2018
822
13

Autophagy and Tumor Metabolism.
Alec C Kimmelman, Eileen White. Cell Metab 2017
353
13

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Matthew R Janes, Jingchuan Zhang, Lian-Sheng Li, Rasmus Hansen, Ulf Peters, Xin Guo, Yuching Chen, Anjali Babbar, Sarah J Firdaus, Levan Darjania,[...]. Cell 2018
371
13

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.
Daniel D Von Hoff, Thomas Ervin, Francis P Arena, E Gabriela Chiorean, Jeffrey Infante, Malcolm Moore, Thomas Seay, Sergei A Tjulandin, Wen Wee Ma, Mansoor N Saleh,[...]. N Engl J Med 2013
12

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.
Jessie Yanxiang Guo, Gizem Karsli-Uzunbas, Robin Mathew, Seena C Aisner, Jurre J Kamphorst, Anne M Strohecker, Guanghua Chen, Sandy Price, Wenyun Lu, Xin Teng,[...]. Genes Dev 2013
374
12

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
12

KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors.
David S Hong, Marwan G Fakih, John H Strickler, Jayesh Desai, Gregory A Durm, Geoffrey I Shapiro, Gerald S Falchook, Timothy J Price, Adrian Sacher, Crystal S Denlinger,[...]. N Engl J Med 2020
232
12

The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
Jill Hallin, Lars D Engstrom, Lauren Hargis, Andrew Calinisan, Ruth Aranda, David M Briere, Niranjan Sudhakar, Vickie Bowcut, Brian R Baer, Joshua A Ballard,[...]. Cancer Discov 2020
282
11

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.
Daniel F Egan, Matthew G H Chun, Mitchell Vamos, Haixia Zou, Juan Rong, Chad J Miller, Hua Jane Lou, Dhanya Raveendra-Panickar, Chih-Cheng Yang, Douglas J Sheffler,[...]. Mol Cell 2015
344
11

Whole genomes redefine the mutational landscape of pancreatic cancer.
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek,[...]. Nature 2015
11

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
11

Drugging the undruggable RAS: Mission possible?
Adrienne D Cox, Stephen W Fesik, Alec C Kimmelman, Ji Luo, Channing J Der. Nat Rev Drug Discov 2014
903
10

A comprehensive survey of Ras mutations in cancer.
Ian A Prior, Paul D Lewis, Carla Mattos. Cancer Res 2012
968
10

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene.
Xueping Qu, Jie Yu, Govind Bhagat, Norihiko Furuya, Hanina Hibshoosh, Andrea Troxel, Jeffrey Rosen, Eeva-Liisa Eskelinen, Noboru Mizushima, Yoshinori Ohsumi,[...]. J Clin Invest 2003
10

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
10

Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.
Jessie Yanxiang Guo, Xin Teng, Saurabh V Laddha, Sirui Ma, Stephen C Van Nostrand, Yang Yang, Sinan Khor, Chang S Chan, Joshua D Rabinowitz, Eileen White. Genes Dev 2016
176
10

Autophagy-deficient mice develop multiple liver tumors.
Akito Takamura, Masaaki Komatsu, Taichi Hara, Ayako Sakamoto, Chieko Kishi, Satoshi Waguri, Yoshinobu Eishi, Okio Hino, Keiji Tanaka, Noboru Mizushima. Genes Dev 2011
785
10

A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients.
Herbert J Zeh, Nathan Bahary, Brian A Boone, Aatur D Singhi, Jennifer Lee Miller-Ocuin, Daniel P Normolle, Amer H Zureikat, Melissa E Hogg, David L Bartlett, Kenneth K Lee,[...]. Clin Cancer Res 2020
41
24

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion.
Mario Mauthe, Idil Orhon, Cecilia Rocchi, Xingdong Zhou, Morten Luhr, Kerst-Jan Hijlkema, Robert P Coppes, Nikolai Engedal, Muriel Mari, Fulvio Reggiori. Autophagy 2018
561
10

Autophagy maintains tumour growth through circulating arginine.
Laura Poillet-Perez, Xiaoqi Xie, Le Zhan, Yang Yang, Daniel W Sharp, Zhixian Sherrie Hu, Xiaoyang Su, Anurag Maganti, Cherry Jiang, Wenyun Lu,[...]. Nature 2018
142
10

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer.
Wantong Yao, Johnathon L Rose, Wei Wang, Sahil Seth, Hong Jiang, Ayumu Taguchi, Jintan Liu, Liang Yan, Avnish Kapoor, Pingping Hou,[...]. Nature 2019
51
17

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.
Zhenyu Yue, Shengkan Jin, Chingwen Yang, Arnold J Levine, Nathaniel Heintz. Proc Natl Acad Sci U S A 2003
9

Microenvironmental autophagy promotes tumour growth.
Nadja S Katheder, Rojyar Khezri, Fergal O'Farrell, Sebastian W Schultz, Ashish Jain, Mohammed M Rahman, Kay O Schink, Theodossis A Theodossiou, Terje Johansen, Gábor Juhász,[...]. Nature 2017
201
9

Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma.
Brian A Boone, Nathan Bahary, Amer H Zureikat, A James Moser, Daniel P Normolle, Wen-Chi Wu, Aatur D Singhi, Phillip Bao, David L Bartlett, Lance A Liotta,[...]. Ann Surg Oncol 2015
107
9

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
9

A randomised, double-blind, placebo-controlled trial of trametinib, an oral MEK inhibitor, in combination with gemcitabine for patients with untreated metastatic adenocarcinoma of the pancreas.
Jeffrey R Infante, Bradley G Somer, Joon Oh Park, Chung-Pin Li, Max E Scheulen, Saifuddin M Kasubhai, Do-Youn Oh, Yuan Liu, Suman Redhu, Klaudia Steplewski,[...]. Eur J Cancer 2014
175
9

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy.
Muhammad Zaeem Noman, Santiago Parpal, Kris Van Moer, Malina Xiao, Yasmin Yu, Jenny Viklund, Angelo De Milito, Meriem Hasmim, Martin Andersson, Ravi K Amaravadi,[...]. Sci Adv 2020
41
21

Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma.
Richard E Royal, Catherine Levy, Keli Turner, Aarti Mathur, Marybeth Hughes, Udai S Kammula, Richard M Sherry, Suzanne L Topalian, James C Yang, Israel Lowy,[...]. J Immunother 2010
626
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.