Martin Jendryka, Monika Palchaudhuri, Daniel Ursu, Bastiaan van der Veen, Birgit Liss, Dennis Kätzel, Wiebke Nissen, Anton Pekcec. Sci Rep 2019
Times Cited: 91
Times Cited: 91
Times Cited
Times Co-cited
Similarity
Chemogenetics revealed: DREADD occupancy and activation via converted clozapine.
Juan L Gomez, Jordi Bonaventura, Wojciech Lesniak, William B Mathews, Polina Sysa-Shah, Lionel A Rodriguez, Randall J Ellis, Christopher T Richie, Brandon K Harvey, Robert F Dannals,[...]. Science 2017
Juan L Gomez, Jordi Bonaventura, Wojciech Lesniak, William B Mathews, Polina Sysa-Shah, Lionel A Rodriguez, Randall J Ellis, Christopher T Richie, Brandon K Harvey, Robert F Dannals,[...]. Science 2017
52
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.
Blaine N Armbruster, Xiang Li, Mark H Pausch, Stefan Herlitze, Bryan L Roth. Proc Natl Acad Sci U S A 2007
Blaine N Armbruster, Xiang Li, Mark H Pausch, Stefan Herlitze, Bryan L Roth. Proc Natl Acad Sci U S A 2007
34
The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice.
Daniel F Manvich, Kevin A Webster, Stephanie L Foster, Martilias S Farrell, James C Ritchie, Joseph H Porter, David Weinshenker. Sci Rep 2018
Daniel F Manvich, Kevin A Webster, Stephanie L Foster, Martilias S Farrell, James C Ritchie, Joseph H Porter, David Weinshenker. Sci Rep 2018
32
Clozapine N-Oxide Administration Produces Behavioral Effects in Long-Evans Rats: Implications for Designing DREADD Experiments.
Duncan A A MacLaren, Richard W Browne, Jessica K Shaw, Sandhya Krishnan Radhakrishnan, Prachi Khare, Rodrigo A España, Stewart D Clark. eNeuro 2016
Duncan A A MacLaren, Richard W Browne, Jessica K Shaw, Sandhya Krishnan Radhakrishnan, Prachi Khare, Rodrigo A España, Stewart D Clark. eNeuro 2016
32
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo.
Karen J Thompson, Elham Khajehali, Sophie J Bradley, Jovana S Navarrete, Xi Ping Huang, Samuel Slocum, Jian Jin, Jing Liu, Yan Xiong, Reid H J Olsen,[...]. ACS Pharmacol Transl Sci 2018
Karen J Thompson, Elham Khajehali, Sophie J Bradley, Jovana S Navarrete, Xi Ping Huang, Samuel Slocum, Jian Jin, Jing Liu, Yan Xiong, Reid H J Olsen,[...]. ACS Pharmacol Transl Sci 2018
29
Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.
Georgia M Alexander, Sarah C Rogan, Atheir I Abbas, Blaine N Armbruster, Ying Pei, John A Allen, Randal J Nonneman, John Hartmann, Sheryl S Moy, Miguel A Nicolelis,[...]. Neuron 2009
Georgia M Alexander, Sarah C Rogan, Atheir I Abbas, Blaine N Armbruster, Ying Pei, John A Allen, Randal J Nonneman, John Hartmann, Sheryl S Moy, Miguel A Nicolelis,[...]. Neuron 2009
23
A chemical-genetic approach to study G protein regulation of beta cell function in vivo.
Jean-Marc Guettier, Dinesh Gautam, Marco Scarselli, Inigo Ruiz de Azua, Jian Hua Li, Erica Rosemond, Xiaochao Ma, Frank J Gonzalez, Blaine N Armbruster, Huiyan Lu,[...]. Proc Natl Acad Sci U S A 2009
Jean-Marc Guettier, Dinesh Gautam, Marco Scarselli, Inigo Ruiz de Azua, Jian Hua Li, Erica Rosemond, Xiaochao Ma, Frank J Gonzalez, Blaine N Armbruster, Huiyan Lu,[...]. Proc Natl Acad Sci U S A 2009
18
The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs.
Xin Chen, Hyunah Choo, Xi-Ping Huang, Xiaobao Yang, Orrin Stone, Bryan L Roth, Jian Jin. ACS Chem Neurosci 2015
Xin Chen, Hyunah Choo, Xi-Ping Huang, Xiaobao Yang, Orrin Stone, Bryan L Roth, Jian Jin. ACS Chem Neurosci 2015
17
High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Jordi Bonaventura, Mark A G Eldridge, Feng Hu, Juan L Gomez, Marta Sanchez-Soto, Ara M Abramyan, Sherry Lam, Matthew A Boehm, Christina Ruiz, Mitchell R Farrell,[...]. Nat Commun 2019
Jordi Bonaventura, Mark A G Eldridge, Feng Hu, Juan L Gomez, Marta Sanchez-Soto, Ara M Abramyan, Sherry Lam, Matthew A Boehm, Christina Ruiz, Mitchell R Farrell,[...]. Nat Commun 2019
21
DREADDs (designer receptors exclusively activated by designer drugs): chemogenetic tools with therapeutic utility.
Daniel J Urban, Bryan L Roth. Annu Rev Pharmacol Toxicol 2015
Daniel J Urban, Bryan L Roth. Annu Rev Pharmacol Toxicol 2015
14
A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.
Eyal Vardy, J Elliott Robinson, Chia Li, Reid H J Olsen, Jeffrey F DiBerto, Patrick M Giguere, Flori M Sassano, Xi-Ping Huang, Hu Zhu, Daniel J Urban,[...]. Neuron 2015
Eyal Vardy, J Elliott Robinson, Chia Li, Reid H J Olsen, Jeffrey F DiBerto, Patrick M Giguere, Flori M Sassano, Xi-Ping Huang, Hu Zhu, Daniel J Urban,[...]. Neuron 2015
14
Cre-dependent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) mice.
Hu Zhu, Dipendra K Aryal, Reid H J Olsen, Daniel J Urban, Amanda Swearingen, Stacy Forbes, Bryan L Roth, Ute Hochgeschwender. Genesis 2016
Hu Zhu, Dipendra K Aryal, Reid H J Olsen, Daniel J Urban, Amanda Swearingen, Stacy Forbes, Bryan L Roth, Ute Hochgeschwender. Genesis 2016
13
DREADDS: Use and application in behavioral neuroscience.
Kyle S Smith, David J Bucci, Bryan W Luikart, Stephen V Mahler. Behav Neurosci 2016
Kyle S Smith, David J Bucci, Bryan W Luikart, Stephen V Mahler. Behav Neurosci 2016
13
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Yuji Nagai, Naohisa Miyakawa, Hiroyuki Takuwa, Yukiko Hori, Kei Oyama, Bin Ji, Manami Takahashi, Xi-Ping Huang, Samuel T Slocum, Jeffrey F DiBerto,[...]. Nat Neurosci 2020
Yuji Nagai, Naohisa Miyakawa, Hiroyuki Takuwa, Yukiko Hori, Kei Oyama, Bin Ji, Manami Takahashi, Xi-Ping Huang, Samuel T Slocum, Jeffrey F DiBerto,[...]. Nat Neurosci 2020
15
Behavioral Effects of Acute Systemic Low-Dose Clozapine in Wild-Type Rats: Implications for the Use of DREADDs in Behavioral Neuroscience.
Ann-Kathrin Ilg, Thomas Enkel, Dusan Bartsch, Florian Bähner. Front Behav Neurosci 2018
Ann-Kathrin Ilg, Thomas Enkel, Dusan Bartsch, Florian Bähner. Front Behav Neurosci 2018
33
Chemogenetic tools to interrogate brain functions.
Scott M Sternson, Bryan L Roth. Annu Rev Neurosci 2014
Scott M Sternson, Bryan L Roth. Annu Rev Neurosci 2014
10
Metabolism and Distribution of Clozapine-N-oxide: Implications for Nonhuman Primate Chemogenetics.
Jessica Raper, Ryan D Morrison, J Scott Daniels, Leonard Howell, Jocelyne Bachevalier, Thomas Wichmann, Adriana Galvan. ACS Chem Neurosci 2017
Jessica Raper, Ryan D Morrison, J Scott Daniels, Leonard Howell, Jocelyne Bachevalier, Thomas Wichmann, Adriana Galvan. ACS Chem Neurosci 2017
14
Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics.
Mikail Weston, Teresa Kaserer, Angela Wu, Alexandre Mouravlev, Jenna C Carpenter, Albert Snowball, Samuel Knauss, Melanie von Schimmelmann, Matthew J During, Gabriele Lignani,[...]. Sci Adv 2019
Mikail Weston, Teresa Kaserer, Angela Wu, Alexandre Mouravlev, Jenna C Carpenter, Albert Snowball, Samuel Knauss, Melanie von Schimmelmann, Matthew J During, Gabriele Lignani,[...]. Sci Adv 2019
28
Chemogenetic synaptic silencing of neural circuits localizes a hypothalamus→midbrain pathway for feeding behavior.
Tevye J Stachniak, Anirvan Ghosh, Scott M Sternson. Neuron 2014
Tevye J Stachniak, Anirvan Ghosh, Scott M Sternson. Neuron 2014
8
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.
Stephen V Mahler, Elena M Vazey, Jacob T Beckley, Colby R Keistler, Ellen M McGlinchey, Jennifer Kaufling, Steven P Wilson, Karl Deisseroth, John J Woodward, Gary Aston-Jones. Nat Neurosci 2014
Stephen V Mahler, Elena M Vazey, Jacob T Beckley, Colby R Keistler, Ellen M McGlinchey, Jennifer Kaufling, Steven P Wilson, Karl Deisseroth, John J Woodward, Gary Aston-Jones. Nat Neurosci 2014
8
CNO Evil? Considerations for the Use of DREADDs in Behavioral Neuroscience.
Stephen V Mahler, Gary Aston-Jones. Neuropsychopharmacology 2018
Stephen V Mahler, Gary Aston-Jones. Neuropsychopharmacology 2018
10
Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons.
Daniel J Urban, Hu Zhu, Catherine A Marcinkiewcz, Michael Michaelides, Hidehiro Oshibuchi, Darren Rhea, Dipendra K Aryal, Martilias S Farrell, Emily Lowery-Gionta, Reid H J Olsen,[...]. Neuropsychopharmacology 2016
Daniel J Urban, Hu Zhu, Catherine A Marcinkiewcz, Michael Michaelides, Hidehiro Oshibuchi, Darren Rhea, Dipendra K Aryal, Martilias S Farrell, Emily Lowery-Gionta, Reid H J Olsen,[...]. Neuropsychopharmacology 2016
9
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.
Michael J Krashes, Shuichi Koda, ChianPing Ye, Sarah C Rogan, Andrew C Adams, Daniel S Cusher, Eleftheria Maratos-Flier, Bryan L Roth, Bradford B Lowell. J Clin Invest 2011
Michael J Krashes, Shuichi Koda, ChianPing Ye, Sarah C Rogan, Andrew C Adams, Daniel S Cusher, Eleftheria Maratos-Flier, Bryan L Roth, Bradford B Lowell. J Clin Invest 2011
8
Chemical and genetic engineering of selective ion channel-ligand interactions.
Christopher J Magnus, Peter H Lee, Deniz Atasoy, Helen H Su, Loren L Looger, Scott M Sternson. Science 2011
Christopher J Magnus, Peter H Lee, Deniz Atasoy, Helen H Su, Loren L Looger, Scott M Sternson. Science 2011
7
Ultrapotent chemogenetics for research and potential clinical applications.
Christopher J Magnus, Peter H Lee, Jordi Bonaventura, Roland Zemla, Juan L Gomez, Melissa H Ramirez, Xing Hu, Adriana Galvan, Jayeeta Basu, Michael Michaelides,[...]. Science 2019
Christopher J Magnus, Peter H Lee, Jordi Bonaventura, Roland Zemla, Juan L Gomez, Melissa H Ramirez, Xing Hu, Adriana Galvan, Jayeeta Basu, Michael Michaelides,[...]. Science 2019
11
Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking.
Michael D Scofield, Heather A Boger, Rachel J Smith, Hao Li, Philip G Haydon, Peter W Kalivas. Biol Psychiatry 2015
Michael D Scofield, Heather A Boger, Rachel J Smith, Hao Li, Philip G Haydon, Peter W Kalivas. Biol Psychiatry 2015
7
The Use of DREADDs to Deconstruct Behavior.
Paul D Whissell, Sarasa Tohyama, Loren J Martin. Front Genet 2016
Paul D Whissell, Sarasa Tohyama, Loren J Martin. Front Genet 2016
10
Modulation of the autonomic nervous system and behaviour by acute glial cell Gq protein-coupled receptor activation in vivo.
Cendra Agulhon, Kristen M Boyt, Alison Xiaoqiao Xie, Francois Friocourt, Bryan L Roth, Ken D McCarthy. J Physiol 2013
Cendra Agulhon, Kristen M Boyt, Alison Xiaoqiao Xie, Francois Friocourt, Bryan L Roth, Ken D McCarthy. J Physiol 2013
7
Design and functional characterization of a novel, arrestin-biased designer G protein-coupled receptor.
Ken-ichiro Nakajima, Jürgen Wess. Mol Pharmacol 2012
Ken-ichiro Nakajima, Jürgen Wess. Mol Pharmacol 2012
6
Parvalbumin-positive interneurons mediate neocortical-hippocampal interactions that are necessary for memory consolidation.
Frances Xia, Blake A Richards, Matthew M Tran, Sheena A Josselyn, Kaori Takehara-Nishiuchi, Paul W Frankland. Elife 2017
Frances Xia, Blake A Richards, Matthew M Tran, Sheena A Josselyn, Kaori Takehara-Nishiuchi, Paul W Frankland. Elife 2017
6
The Chemogenetic Receptor Ligand Clozapine N-Oxide Induces in vivo Neuroreceptor Occupancy and Reduces Striatal Glutamate Levels.
Simone Bærentzen, Agata Casado-Sainz, Denise Lange, Vladimir Shalgunov, Isabel Martinez Tejada, Mengfei Xiong, Elina T L'Estrade, Fraser G Edgar, Hedok Lee, Matthias M Herth,[...]. Front Neurosci 2019
Simone Bærentzen, Agata Casado-Sainz, Denise Lange, Vladimir Shalgunov, Isabel Martinez Tejada, Mengfei Xiong, Elina T L'Estrade, Fraser G Edgar, Hedok Lee, Matthias M Herth,[...]. Front Neurosci 2019
37
Chemogenetic Tools for Causal Cellular and Neuronal Biology.
Deniz Atasoy, Scott M Sternson. Physiol Rev 2018
Deniz Atasoy, Scott M Sternson. Physiol Rev 2018
9
Chronic activation of a designer G(q)-coupled receptor improves β cell function.
Shalini Jain, Inigo Ruiz de Azua, Huiyan Lu, Morris F White, Jean-Marc Guettier, Jürgen Wess. J Clin Invest 2013
Shalini Jain, Inigo Ruiz de Azua, Huiyan Lu, Morris F White, Jean-Marc Guettier, Jürgen Wess. J Clin Invest 2013
6
Optimizing clozapine for chemogenetic neuromodulation of somatosensory cortex.
Jongwook Cho, Seungjun Ryu, Sunwoo Lee, Junsoo Kim, Hyoung-Ihl Kim. Sci Rep 2020
Jongwook Cho, Seungjun Ryu, Sunwoo Lee, Junsoo Kim, Hyoung-Ihl Kim. Sci Rep 2020
54
Chemical-genetic attenuation of focal neocortical seizures.
Dennis Kätzel, Elizabeth Nicholson, Stephanie Schorge, Matthew C Walker, Dimitri M Kullmann. Nat Commun 2014
Dennis Kätzel, Elizabeth Nicholson, Stephanie Schorge, Matthew C Walker, Dimitri M Kullmann. Nat Commun 2014
5
Deconstruction of a neural circuit for hunger.
Deniz Atasoy, J Nicholas Betley, Helen H Su, Scott M Sternson. Nature 2012
Deniz Atasoy, J Nicholas Betley, Helen H Su, Scott M Sternson. Nature 2012
5
Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory.
Hu Zhu, Kristen E Pleil, Daniel J Urban, Sheryl S Moy, Thomas L Kash, Bryan L Roth. Neuropsychopharmacology 2014
Hu Zhu, Kristen E Pleil, Daniel J Urban, Sheryl S Moy, Thomas L Kash, Bryan L Roth. Neuropsychopharmacology 2014
5
Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types.
Natale R Sciolino, Nicholas W Plummer, Yu-Wei Chen, Georgia M Alexander, Sabrina D Robertson, Serena M Dudek, Zoe A McElligott, Patricia Jensen. Cell Rep 2016
Natale R Sciolino, Nicholas W Plummer, Yu-Wei Chen, Georgia M Alexander, Sabrina D Robertson, Serena M Dudek, Zoe A McElligott, Patricia Jensen. Cell Rep 2016
9
Gi-DREADD Expression in Peripheral Nerves Produces Ligand-Dependent Analgesia, as well as Ligand-Independent Functional Changes in Sensory Neurons.
Jami L Saloman, Nicole N Scheff, Lindsey M Snyder, Sarah E Ross, Brian M Davis, Michael S Gold. J Neurosci 2016
Jami L Saloman, Nicole N Scheff, Lindsey M Snyder, Sarah E Ross, Brian M Davis, Michael S Gold. J Neurosci 2016
8
Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors.
Bin Ji, Hiroyuki Kaneko, Takafumi Minamimoto, Haruhisa Inoue, Hiroki Takeuchi, Katsushi Kumata, Ming-Rong Zhang, Ichio Aoki, Chie Seki, Maiko Ono,[...]. J Neurosci 2016
Bin Ji, Hiroyuki Kaneko, Takafumi Minamimoto, Haruhisa Inoue, Hiroki Takeuchi, Katsushi Kumata, Ming-Rong Zhang, Ichio Aoki, Chie Seki, Maiko Ono,[...]. J Neurosci 2016
25
PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation.
Yuji Nagai, Erika Kikuchi, Walter Lerchner, Ken-Ichi Inoue, Bin Ji, Mark A G Eldridge, Hiroyuki Kaneko, Yasuyuki Kimura, Arata Oh-Nishi, Yukiko Hori,[...]. Nat Commun 2016
Yuji Nagai, Erika Kikuchi, Walter Lerchner, Ken-Ichi Inoue, Bin Ji, Mark A G Eldridge, Hiroyuki Kaneko, Yasuyuki Kimura, Arata Oh-Nishi, Yukiko Hori,[...]. Nat Commun 2016
8
The Rhesus Monkey Connectome Predicts Disrupted Functional Networks Resulting from Pharmacogenetic Inactivation of the Amygdala.
David S Grayson, Eliza Bliss-Moreau, Christopher J Machado, Jeffrey Bennett, Kelly Shen, Kathleen A Grant, Damien A Fair, David G Amaral. Neuron 2016
David S Grayson, Eliza Bliss-Moreau, Christopher J Machado, Jeffrey Bennett, Kelly Shen, Kathleen A Grant, Damien A Fair, David G Amaral. Neuron 2016
5
5
Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems.
Ken Y Chan, Min J Jang, Bryan B Yoo, Alon Greenbaum, Namita Ravi, Wei-Li Wu, Luis Sánchez-Guardado, Carlos Lois, Sarkis K Mazmanian, Benjamin E Deverman,[...]. Nat Neurosci 2017
Ken Y Chan, Min J Jang, Bryan B Yoo, Alon Greenbaum, Namita Ravi, Wei-Li Wu, Luis Sánchez-Guardado, Carlos Lois, Sarkis K Mazmanian, Benjamin E Deverman,[...]. Nat Neurosci 2017
5
Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement.
Adar Adamsky, Adi Kol, Tirzah Kreisel, Adi Doron, Nofar Ozeri-Engelhard, Talia Melcer, Ron Refaeli, Henrike Horn, Limor Regev, Maya Groysman,[...]. Cell 2018
Adar Adamsky, Adi Kol, Tirzah Kreisel, Adi Doron, Nofar Ozeri-Engelhard, Talia Melcer, Ron Refaeli, Henrike Horn, Limor Regev, Maya Groysman,[...]. Cell 2018
5
Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence.
Cecilia Bull, Kelen C C Freitas, Shiping Zou, Ryan S Poland, Wahab A Syed, Daniel J Urban, Sabrina C Minter, Keith L Shelton, Kurt F Hauser, S Stevens Negus,[...]. Neuropsychopharmacology 2014
Cecilia Bull, Kelen C C Freitas, Shiping Zou, Ryan S Poland, Wahab A Syed, Daniel J Urban, Sabrina C Minter, Keith L Shelton, Kurt F Hauser, S Stevens Negus,[...]. Neuropsychopharmacology 2014
5
Synapse-specific astrocyte gating of amygdala-related behavior.
Mario Martin-Fernandez, Stephanie Jamison, Laurie M Robin, Zhe Zhao, Eduardo D Martin, Juan Aguilar, Michael A Benneyworth, Giovanni Marsicano, Alfonso Araque. Nat Neurosci 2017
Mario Martin-Fernandez, Stephanie Jamison, Laurie M Robin, Zhe Zhao, Eduardo D Martin, Juan Aguilar, Michael A Benneyworth, Giovanni Marsicano, Alfonso Araque. Nat Neurosci 2017
5
Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse.
Stephen V Mahler, Zachary D Brodnik, Brittney M Cox, William C Buchta, Brandon S Bentzley, Julian Quintanilla, Zackary A Cope, Edwin C Lin, Matthew D Riedy, Michael D Scofield,[...]. J Neurosci 2019
Stephen V Mahler, Zachary D Brodnik, Brittney M Cox, William C Buchta, Brandon S Bentzley, Julian Quintanilla, Zackary A Cope, Edwin C Lin, Matthew D Riedy, Michael D Scofield,[...]. J Neurosci 2019
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.