Marc S Rendell. Drug Des Devel Ther 2019
Times Cited: 8
Times Cited: 8
Times Cited
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Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
Yibing Wang, Yang Lou, Jiang Wang, Dan Li, Hui Chen, Tiannan Zheng, Chunmei Xia, Xiaohan Song, Tiancheng Dong, Jingya Li,[...]. Eur J Med Chem 2019
Yibing Wang, Yang Lou, Jiang Wang, Dan Li, Hui Chen, Tiannan Zheng, Chunmei Xia, Xiaohan Song, Tiancheng Dong, Jingya Li,[...]. Eur J Med Chem 2019
25
The Latest Research and Development into the Antibody-Drug Conjugate, [fam-] Trastuzumab Deruxtecan (DS-8201a), for HER2 Cancer Therapy.
Takashi Nakada, Kiyoshi Sugihara, Takahiro Jikoh, Yuki Abe, Toshinori Agatsuma. Chem Pharm Bull (Tokyo) 2019
Takashi Nakada, Kiyoshi Sugihara, Takahiro Jikoh, Yuki Abe, Toshinori Agatsuma. Chem Pharm Bull (Tokyo) 2019
25
A review of sotagliflozin for use in type 1 diabetes.
Wesley Nuffer, Briana Williams, Jennifer M Trujillo. Ther Adv Endocrinol Metab 2019
Wesley Nuffer, Briana Williams, Jennifer M Trujillo. Ther Adv Endocrinol Metab 2019
28
Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives.
Chiara Maria Assunta Cefalo, Francesca Cinti, Simona Moffa, Flavia Impronta, Gian Pio Sorice, Teresa Mezza, Alfredo Pontecorvi, Andrea Giaccari. Cardiovasc Diabetol 2019
Chiara Maria Assunta Cefalo, Francesca Cinti, Simona Moffa, Flavia Impronta, Gian Pio Sorice, Teresa Mezza, Alfredo Pontecorvi, Andrea Giaccari. Cardiovasc Diabetol 2019
25
Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments.
Konstantinos A Toulis, Krishnarajah Nirantharakumar, Chrysa Pourzitaki, Anthony H Barnett, Abd A Tahrani. Drugs 2020
Konstantinos A Toulis, Krishnarajah Nirantharakumar, Chrysa Pourzitaki, Anthony H Barnett, Abd A Tahrani. Drugs 2020
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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle,[...]. N Engl J Med 2015
25
Efficacy and safety of dual SGLT 1/2 inhibitor sotagliflozin in type 1 diabetes: meta-analysis of randomised controlled trials.
Giovanni Musso, Roberto Gambino, Maurizio Cassader, Elena Paschetta. BMJ 2019
Giovanni Musso, Roberto Gambino, Maurizio Cassader, Elena Paschetta. BMJ 2019
25
Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies.
Anne L Peters, Darren K McGuire, Thomas Danne, Jake A Kushner, Helena W Rodbard, Ketan Dhatariya, Sangeeta Sawhney, Phillip Banks, Wenjun Jiang, Michael J Davies,[...]. Diabetes Care 2020
Anne L Peters, Darren K McGuire, Thomas Danne, Jake A Kushner, Helena W Rodbard, Ketan Dhatariya, Sangeeta Sawhney, Phillip Banks, Wenjun Jiang, Michael J Davies,[...]. Diabetes Care 2020
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Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.
Deepak L Bhatt, Michael Szarek, Bertram Pitt, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Silvio E Inzucchi, Mikhail N Kosiborod,[...]. N Engl J Med 2021
Deepak L Bhatt, Michael Szarek, Bertram Pitt, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Silvio E Inzucchi, Mikhail N Kosiborod,[...]. N Engl J Med 2021
25
Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.
Deepak L Bhatt, Michael Szarek, P Gabriel Steg, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Adriaan A Voors, Marco Metra,[...]. N Engl J Med 2021
Deepak L Bhatt, Michael Szarek, P Gabriel Steg, Christopher P Cannon, Lawrence A Leiter, Darren K McGuire, Julia B Lewis, Matthew C Riddle, Adriaan A Voors, Marco Metra,[...]. N Engl J Med 2021
25
Monoamine oxidase isoenzymes: genes, functions and targets for behavior and cancer therapy.
Jean C Shih. J Neural Transm (Vienna) 2018
Jean C Shih. J Neural Transm (Vienna) 2018
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Neuronal serotonin regulates growth of the intestinal mucosa in mice.
Erica R Gross, Michael D Gershon, Kara G Margolis, Zoya V Gertsberg, Zhishan Li, Robert A Cowles. Gastroenterology 2012
Erica R Gross, Michael D Gershon, Kara G Margolis, Zoya V Gertsberg, Zhishan Li, Robert A Cowles. Gastroenterology 2012
12
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.
Lorna A Farrelly, Robert E Thompson, Shuai Zhao, Ashley E Lepack, Yang Lyu, Natarajan V Bhanu, Baichao Zhang, Yong-Hwee E Loh, Aarthi Ramakrishnan, Krishna C Vadodaria,[...]. Nature 2019
Lorna A Farrelly, Robert E Thompson, Shuai Zhao, Ashley E Lepack, Yang Lyu, Natarajan V Bhanu, Baichao Zhang, Yong-Hwee E Loh, Aarthi Ramakrishnan, Krishna C Vadodaria,[...]. Nature 2019
12
Gene therapy by targeted adenovirus-mediated knockdown of pulmonary endothelial Tph1 attenuates hypoxia-induced pulmonary hypertension.
Ian Morecroft, Katie White, Paola Caruso, Margaret Nilsen, Lynn Loughlin, Raul Alba, Paul N Reynolds, Sergei M Danilov, Andrew H Baker, Margaret R Maclean. Mol Ther 2012
Ian Morecroft, Katie White, Paola Caruso, Margaret Nilsen, Lynn Loughlin, Raul Alba, Paul N Reynolds, Sergei M Danilov, Andrew H Baker, Margaret R Maclean. Mol Ther 2012
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Serotonin signals through a gut-liver axis to regulate hepatic steatosis.
Wonsuk Choi, Jun Namkung, Inseon Hwang, Hyeongseok Kim, Ajin Lim, Hye Jung Park, Hye Won Lee, Kwang-Hyub Han, Seongyeol Park, Ji-Seon Jeong,[...]. Nat Commun 2018
Wonsuk Choi, Jun Namkung, Inseon Hwang, Hyeongseok Kim, Ajin Lim, Hye Jung Park, Hye Won Lee, Kwang-Hyub Han, Seongyeol Park, Ji-Seon Jeong,[...]. Nat Commun 2018
12
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia.
Saadia Eddahibi, Christophe Guignabert, Anne-Marie Barlier-Mur, Laurence Dewachter, Elie Fadel, Philippe Dartevelle, Marc Humbert, Gerald Simonneau, Naïma Hanoun, Françoise Saurini,[...]. Circulation 2006
Saadia Eddahibi, Christophe Guignabert, Anne-Marie Barlier-Mur, Laurence Dewachter, Elie Fadel, Philippe Dartevelle, Marc Humbert, Gerald Simonneau, Naïma Hanoun, Françoise Saurini,[...]. Circulation 2006
12
Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.
Zhishan Li, Alcmène Chalazonitis, Yung-Yu Huang, J John Mann, Kara Gross Margolis, Qi Melissa Yang, Dolly O Kim, Francine Côté, Jacques Mallet, Michael D Gershon. J Neurosci 2011
Zhishan Li, Alcmène Chalazonitis, Yung-Yu Huang, J John Mann, Kara Gross Margolis, Qi Melissa Yang, Dolly O Kim, Francine Côté, Jacques Mallet, Michael D Gershon. J Neurosci 2011
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Boosting serotonin in the brain: is it time to revamp the treatment of depression?
Mariana P Torrente, Alan J Gelenberg, Kent E Vrana. J Psychopharmacol 2012
Mariana P Torrente, Alan J Gelenberg, Kent E Vrana. J Psychopharmacol 2012
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Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice.
A Fabre, J Marchal-Sommé, S Marchand-Adam, C Quesnel, R Borie, M Dehoux, C Ruffié, J Callebert, J-M Launay, D Hénin,[...]. Eur Respir J 2008
A Fabre, J Marchal-Sommé, S Marchand-Adam, C Quesnel, R Borie, M Dehoux, C Ruffié, J Callebert, J-M Launay, D Hénin,[...]. Eur Respir J 2008
12
Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice.
Yvonne Dempsie, Ian Morecroft, David J Welsh, Neil A MacRitchie, Nigel Herold, Lynn Loughlin, Margaret Nilsen, Andrew J Peacock, Anthony Harmar, Michael Bader,[...]. Circulation 2008
Yvonne Dempsie, Ian Morecroft, David J Welsh, Neil A MacRitchie, Nigel Herold, Lynn Loughlin, Margaret Nilsen, Andrew J Peacock, Anthony Harmar, Michael Bader,[...]. Circulation 2008
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Triptans and migraine: advances in use, administration, formulation, and development.
Amanda E Macone, Michael D Perloff. Expert Opin Pharmacother 2017
Amanda E Macone, Michael D Perloff. Expert Opin Pharmacother 2017
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Review of the Ongoing Story of Appetite Suppressants, Serotonin Pathway, and Pulmonary Vascular Disease.
Isabel S Bazan, Wassim H Fares. Am J Cardiol 2016
Isabel S Bazan, Wassim H Fares. Am J Cardiol 2016
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Safety of antipsychotic drugs: focus on therapeutic and adverse effects.
Felix-Martin Werner, Rafael Coveñas. Expert Opin Drug Saf 2014
Felix-Martin Werner, Rafael Coveñas. Expert Opin Drug Saf 2014
12
Serotonin paracrine signaling in tissue fibrosis.
Derek A Mann, Fiona Oakley. Biochim Biophys Acta 2013
Derek A Mann, Fiona Oakley. Biochim Biophys Acta 2013
12
Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
Matthew H Kulke, Thomas O'Dorisio, Alexandria Phan, Emily Bergsland, Linda Law, Phillip Banks, Joel Freiman, Kenny Frazier, Jessica Jackson, James C Yao,[...]. Endocr Relat Cancer 2014
Matthew H Kulke, Thomas O'Dorisio, Alexandria Phan, Emily Bergsland, Linda Law, Phillip Banks, Joel Freiman, Kenny Frazier, Jessica Jackson, James C Yao,[...]. Endocr Relat Cancer 2014
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A unique central tryptophan hydroxylase isoform.
Diego J Walther, Michael Bader. Biochem Pharmacol 2003
Diego J Walther, Michael Bader. Biochem Pharmacol 2003
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Identification of enteramine, the specific hormone of the enterochromaffin cell system, as 5-hydroxytryptamine.
V ERSPAMER, B ASERO. Nature 1952
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12
Tryptophan hydroxylase 1 Inhibition Impacts Pulmonary Vascular Remodeling in Two Rat Models of Pulmonary Hypertension.
Robert J Aiello, Patricia-Ann Bourassa, Qing Zhang, Jeffrey Dubins, Daniel R Goldberg, Stéphane De Lombaert, Marc Humbert, Christophe Guignabert, Maria A Cavasin, Timothy A McKinsey,[...]. J Pharmacol Exp Ther 2017
Robert J Aiello, Patricia-Ann Bourassa, Qing Zhang, Jeffrey Dubins, Daniel R Goldberg, Stéphane De Lombaert, Marc Humbert, Christophe Guignabert, Maria A Cavasin, Timothy A McKinsey,[...]. J Pharmacol Exp Ther 2017
12
Lrp5 regulation of bone mass and serotonin synthesis in the gut.
Aruna Kode, Arnaud Obri, Riccardo Paone, Stavroula Kousteni, Patricia Ducy, Gerard Karsenty. Nat Med 2014
Aruna Kode, Arnaud Obri, Riccardo Paone, Stavroula Kousteni, Patricia Ducy, Gerard Karsenty. Nat Med 2014
12
Important role of mucosal serotonin in colonic propulsion and peristaltic reflexes: in vitro analyses in mice lacking tryptophan hydroxylase 1.
Dante J Heredia, Michael D Gershon, Sang Don Koh, Robert D Corrigan, Takanubu Okamoto, Terence K Smith. J Physiol 2013
Dante J Heredia, Michael D Gershon, Sang Don Koh, Robert D Corrigan, Takanubu Okamoto, Terence K Smith. J Physiol 2013
12
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis.
Yajun Cui, Paul J Niziolek, Bryan T MacDonald, Natalia Alenina, Susann Matthes, Christina M Jacobsen, Ronald A Conlon, Robert Brommage, David R Powell, Xi He,[...]. Nat Med 2014
Yajun Cui, Paul J Niziolek, Bryan T MacDonald, Natalia Alenina, Susann Matthes, Christina M Jacobsen, Ronald A Conlon, Robert Brommage, David R Powell, Xi He,[...]. Nat Med 2014
12
Serotonin has a key role in pathogenesis of experimental colitis.
Jean-Eric Ghia, Nan Li, Huaqing Wang, Matthew Collins, Yikang Deng, Rami T El-Sharkawy, Francine Côté, Jacques Mallet, Waliul I Khan. Gastroenterology 2009
Jean-Eric Ghia, Nan Li, Huaqing Wang, Matthew Collins, Yikang Deng, Rami T El-Sharkawy, Francine Côté, Jacques Mallet, Waliul I Khan. Gastroenterology 2009
12
Production of serotonin by tryptophan hydroxylase 1 and release via platelets contribute to allergic airway inflammation.
Thorsten Dürk, Daniel Duerschmied, Tobias Müller, Melanie Grimm, Sebastian Reuter, Rodolfo Paula Vieira, Korcan Ayata, Sanja Cicko, Stephan Sorichter, Diego J Walther,[...]. Am J Respir Crit Care Med 2013
Thorsten Dürk, Daniel Duerschmied, Tobias Müller, Melanie Grimm, Sebastian Reuter, Rodolfo Paula Vieira, Korcan Ayata, Sanja Cicko, Stephan Sorichter, Diego J Walther,[...]. Am J Respir Crit Care Med 2013
12
Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine.
Kara Gross Margolis, Korey Stevanovic, Zhishan Li, Qi Melissa Yang, Tamas Oravecz, Brian Zambrowicz, Kanchan G Jhaver, Alexander Diacou, Michael D Gershon. Gut 2014
Kara Gross Margolis, Korey Stevanovic, Zhishan Li, Qi Melissa Yang, Tamas Oravecz, Brian Zambrowicz, Kanchan G Jhaver, Alexander Diacou, Michael D Gershon. Gut 2014
12
Growth retardation and altered autonomic control in mice lacking brain serotonin.
Natalia Alenina, Dana Kikic, Mihail Todiras, Valentina Mosienko, Fatimunnisa Qadri, Ralph Plehm, Philipp Boyé, Larissa Vilianovitch, Reinhard Sohr, Katja Tenner,[...]. Proc Natl Acad Sci U S A 2009
Natalia Alenina, Dana Kikic, Mihail Todiras, Valentina Mosienko, Fatimunnisa Qadri, Ralph Plehm, Philipp Boyé, Larissa Vilianovitch, Reinhard Sohr, Katja Tenner,[...]. Proc Natl Acad Sci U S A 2009
12
Multinational comparison of new antidepressant use in older adults: a cohort study.
Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li,[...]. BMJ Open 2019
Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li,[...]. BMJ Open 2019
12
Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation.
Maximilian Mauler, Nadine Herr, Claudia Schoenichen, Thilo Witsch, Timoteo Marchini, Carmen Härdtner, Christoph Koentges, Korbinian Kienle, Véronique Ollivier, Maximilian Schell,[...]. Circulation 2019
Maximilian Mauler, Nadine Herr, Claudia Schoenichen, Thilo Witsch, Timoteo Marchini, Carmen Härdtner, Christoph Koentges, Korbinian Kienle, Véronique Ollivier, Maximilian Schell,[...]. Circulation 2019
12
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice.
Antonio Nocito, Panco Georgiev, Felix Dahm, Wolfram Jochum, Michael Bader, Rolf Graf, Pierre-Alain Clavien. Hepatology 2007
Antonio Nocito, Panco Georgiev, Felix Dahm, Wolfram Jochum, Michael Bader, Rolf Graf, Pierre-Alain Clavien. Hepatology 2007
12
5-hydroxytryptamine release into human jejunum by cholera toxin.
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Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice.
Jingyao Zhang, Qing Pang, Sidong Song, Ruiyao Zhang, Sushun Liu, Zichao Huang, Qifei Wu, Yang Liu, Chang Liu. Shock 2015
Jingyao Zhang, Qing Pang, Sidong Song, Ruiyao Zhang, Sushun Liu, Zichao Huang, Qifei Wu, Yang Liu, Chang Liu. Shock 2015
12
Serotonin regulates amylase secretion and acinar cell damage during murine pancreatitis.
Sabrina Sonda, Alberto B Silva, Kamile Grabliauskaite, Enrica Saponara, Achim Weber, Jae-Hwi Jang, Richard A Züllig, Martha Bain, Theresia Reding Graf, Adrian B Hehl,[...]. Gut 2013
Sabrina Sonda, Alberto B Silva, Kamile Grabliauskaite, Enrica Saponara, Achim Weber, Jae-Hwi Jang, Richard A Züllig, Martha Bain, Theresia Reding Graf, Adrian B Hehl,[...]. Gut 2013
12
Selective serotonin reuptake inhibitors and myocardial infarction.
W H Sauer, J A Berlin, S E Kimmel. Circulation 2001
W H Sauer, J A Berlin, S E Kimmel. Circulation 2001
12
Telotristat ethyl: proof of principle and the first oral agent in the management of well-differentiated metastatic neuroendocrine tumor and carcinoid syndrome diarrhea.
Muhammad Masab, Muhammad Wasif Saif. Cancer Chemother Pharmacol 2017
Muhammad Masab, Muhammad Wasif Saif. Cancer Chemother Pharmacol 2017
12
Transglutaminase 2-mediated serotonylation in pulmonary hypertension.
K C Penumatsa, B L Fanburg. Am J Physiol Lung Cell Mol Physiol 2014
K C Penumatsa, B L Fanburg. Am J Physiol Lung Cell Mol Physiol 2014
12
Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
Antonio Nocito, Felix Dahm, Wolfram Jochum, Jae Hwi Jang, Panco Georgiev, Michael Bader, Eberhard Ludwig Renner, Pierre-Alain Clavien. Gastroenterology 2007
Antonio Nocito, Felix Dahm, Wolfram Jochum, Jae Hwi Jang, Panco Georgiev, Michael Bader, Eberhard Ludwig Renner, Pierre-Alain Clavien. Gastroenterology 2007
12
Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial.
Marianne Pavel, Dieter Hörsch, Martyn Caplin, John Ramage, Thomas Seufferlein, Juan Valle, Phillip Banks, Pablo Lapuerta, Arthur Sands, Brian Zambrowicz,[...]. J Clin Endocrinol Metab 2015
Marianne Pavel, Dieter Hörsch, Martyn Caplin, John Ramage, Thomas Seufferlein, Juan Valle, Phillip Banks, Pablo Lapuerta, Arthur Sands, Brian Zambrowicz,[...]. J Clin Endocrinol Metab 2015
12
Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome.
Lowell B Anthony, Matthew H Kulke, Martyn E Caplin, Emily Bergsland, Kjell Öberg, Marianne Pavel, Dieter Hörsch, Richard R P Warner, Thomas M O'Dorisio, Joseph S Dillon,[...]. Oncologist 2019
Lowell B Anthony, Matthew H Kulke, Martyn E Caplin, Emily Bergsland, Kjell Öberg, Marianne Pavel, Dieter Hörsch, Richard R P Warner, Thomas M O'Dorisio, Joseph S Dillon,[...]. Oncologist 2019
12
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.
Vijay K Yadav, Je-Hwang Ryu, Nina Suda, Kenji F Tanaka, Jay A Gingrich, Günther Schütz, Francis H Glorieux, Cherie Y Chiang, Jeffrey D Zajac, Karl L Insogna,[...]. Cell 2008
Vijay K Yadav, Je-Hwang Ryu, Nina Suda, Kenji F Tanaka, Jay A Gingrich, Günther Schütz, Francis H Glorieux, Cherie Y Chiang, Jeffrey D Zajac, Karl L Insogna,[...]. Cell 2008
12
Drugs which influence serotonin transporter and serotonergic receptors: Pharmacological and clinical properties in the treatment of depression.
Przemysław Paweł Taciak, Natalia Lysenko, Aleksander Paweł Mazurek. Pharmacol Rep 2018
Przemysław Paweł Taciak, Natalia Lysenko, Aleksander Paweł Mazurek. Pharmacol Rep 2018
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.