A citation-based method for searching scientific literature

Sara E Espinoza, Nicolas Musi, Chen-Pin Wang, Joel Michalek, Beverly Orsak, Terry Romo, Becky Powers, Alice Conde, Melody Moris, Darcy Bair-Kelps, Yan Li, Vinutha Ganapathy, Tyson E Jergensen, Lauri C Kelly, Rozmin Jiwani. J Gerontol A Biol Sci Med Sci 2020
Times Cited: 12







List of co-cited articles
105 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
426
58

Fisetin is a senotherapeutic that extends health and lifespan.
Matthew J Yousefzadeh, Yi Zhu, Sara J McGowan, Luise Angelini, Heike Fuhrmann-Stroissnigg, Ming Xu, Yuan Yuan Ling, Kendra I Melos, Tamar Pirtskhalava, Christina L Inman,[...]. EBioMedicine 2018
206
41

Frailty in older adults: evidence for a phenotype.
L P Fried, C M Tangen, J Walston, A B Newman, C Hirsch, J Gottdiener, T Seeman, R Tracy, W J Kop, G Burke,[...]. J Gerontol A Biol Sci Med Sci 2001
41

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
597
33

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
690
33

The role of senescent cells in ageing.
Jan M van Deursen. Nature 2014
33

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
505
33

Differential effects of metformin on age related comorbidities in older men with type 2 diabetes.
Chen-Pin Wang, Carlos Lorenzo, Samy L Habib, Booil Jo, Sara E Espinoza. J Diabetes Complications 2017
50
33


Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2.
Wouter De Haes, Lotte Frooninckx, Roel Van Assche, Arne Smolders, Geert Depuydt, Johan Billen, Bart P Braeckman, Liliane Schoofs, Liesbet Temmerman. Proc Natl Acad Sci U S A 2014
184
33

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
Jamie N Justice, Anoop M Nambiar, Tamar Tchkonia, Nathan K LeBrasseur, Rodolfo Pascual, Shahrukh K Hashmi, Larissa Prata, Michal M Masternak, Stephen B Kritchevsky, Nicolas Musi,[...]. EBioMedicine 2019
321
33

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
33


Taming expectations of metformin as a treatment to extend healthspan.
Adam R Konopka, Benjamin F Miller. Geroscience 2019
15
25

Identification of HSP90 inhibitors as a novel class of senolytics.
Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J McGowan, Yi Zhu, Robert W Brooks, Diego Grassi, Siobhan Q Gregg, Jennifer L Stripay, Akaitz Dorronsoro,[...]. Nat Commun 2017
241
25

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
729
25

Frailty in elderly people.
Andrew Clegg, John Young, Steve Iliffe, Marcel Olde Rikkert, Kenneth Rockwood. Lancet 2013
25

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan. N Engl J Med 2002
25

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
251
25

Metformin and Aging: A Review.
Hartmut H Glossmann, Oliver M D Lutz. Gerontology 2019
41
25

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
25

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation.
Olga Moiseeva, Xavier Deschênes-Simard, Emmanuelle St-Germain, Sebastian Igelmann, Geneviève Huot, Alexandra E Cadar, Véronique Bourdeau, Michael N Pollak, Gerardo Ferbeyre. Aging Cell 2013
234
25

Frailty Attenuates the Impact of Metformin on Reducing Mortality in Older Adults with Type 2 Diabetes.
Chen-Pin Wang, Carlos Lorenzo, Sara E Espinoza. J Endocrinol Diabetes Obes 2014
36
25

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
16

Senescent cells: an emerging target for diseases of ageing.
Bennett G Childs, Martina Gluscevic, Darren J Baker, Remi-Martin Laberge, Dan Marquess, Jamie Dananberg, Jan M van Deursen. Nat Rev Drug Discov 2017
394
16

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults.
Ameya S Kulkarni, Erika F Brutsaert, Valentin Anghel, Kehao Zhang, Noah Bloomgarden, Michael Pollak, Jessica C Mar, Meredith Hawkins, Jill P Crandall, Nir Barzilai. Aging Cell 2018
52
16

Anti-ageing pill pushed as bona fide drug.
Erika Check Hayden. Nature 2015
37
16

Meta-analysis: metformin treatment in persons at risk for diabetes mellitus.
Shelley R Salpeter, Nicholas S Buckley, Justin A Kahn, Edwin E Salpeter. Am J Med 2008
149
16

Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults.
Kirsty M Porter, Mary Ward, Catherine F Hughes, Maurice O'Kane, Leane Hoey, Adrian McCann, Anne M Molloy, Conal Cunningham, Miriam C Casey, Fergal Tracey,[...]. J Clin Endocrinol Metab 2019
18
16

Rapamycin and Alzheimer's disease: Time for a clinical trial?
Matt Kaeberlein, Veronica Galvan. Sci Transl Med 2019
53
16

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.
Frank Madeo, Didac Carmona-Gutierrez, Sebastian J Hofer, Guido Kroemer. Cell Metab 2019
165
16

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
783
16

Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis.
Hiroshi Noto, Atsushi Goto, Tetsuro Tsujimoto, Mitsuhiko Noda. PLoS One 2012
374
16

Clinical Trials Targeting Aging and Age-Related Multimorbidity.
Mark A Espeland, Eileen M Crimmins, Brandon R Grossardt, Jill P Crandall, Jonathan A L Gelfond, Tamara B Harris, Stephen B Kritchevsky, JoAnn E Manson, Jennifer G Robinson, Walter A Rocca,[...]. J Gerontol A Biol Sci Med Sci 2017
27
16

Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls.
C A Bannister, S E Holden, S Jenkins-Jones, C Ll Morgan, J P Halcox, G Schernthaner, J Mukherjee, C J Currie. Diabetes Obes Metab 2014
168
16

Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials.
R J Stevens, R Ali, C R Bankhead, M A Bethel, B J Cairns, R P Camisasca, F L Crowe, A J Farmer, S Harrison, J A Hirst,[...]. Diabetologia 2012
125
16

Metformin Activates AMPK through the Lysosomal Pathway.
Chen-Song Zhang, Mengqi Li, Teng Ma, Yue Zong, Jiwen Cui, Jin-Wei Feng, Yu-Qing Wu, Shu-Yong Lin, Sheng-Cai Lin. Cell Metab 2016
112
16

An epigenetic biomarker of aging for lifespan and healthspan.
Morgan E Levine, Ake T Lu, Austin Quach, Brian H Chen, Themistocles L Assimes, Stefania Bandinelli, Lifang Hou, Andrea A Baccarelli, James D Stewart, Yun Li,[...]. Aging (Albany NY) 2018
461
16

mTOR inhibition improves immune function in the elderly.
Joan B Mannick, Giuseppe Del Giudice, Maria Lattanzi, Nicholas M Valiante, Jens Praestgaard, Baisong Huang, Michael A Lonetto, Holden T Maecker, John Kovarik, Simon Carson,[...]. Sci Transl Med 2014
357
16


Genome-wide methylation profiles reveal quantitative views of human aging rates.
Gregory Hannum, Justin Guinney, Ling Zhao, Li Zhang, Guy Hughes, SriniVas Sadda, Brandy Klotzle, Marina Bibikova, Jian-Bing Fan, Yuan Gao,[...]. Mol Cell 2013
16

Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial.
Marco Pahor, Jack M Guralnik, Walter T Ambrosius, Steven Blair, Denise E Bonds, Timothy S Church, Mark A Espeland, Roger A Fielding, Thomas M Gill, Erik J Groessl,[...]. JAMA 2014
710
16


Metformin, Lifestyle Intervention, and Cognition in the Diabetes Prevention Program Outcomes Study.
José A Luchsinger, Yong Ma, Costas A Christophi, Hermes Florez, Sherita H Golden, Helen Hazuda, Jill Crandall, Elizabeth Venditti, Karol Watson, Susan Jeffries,[...]. Diabetes Care 2017
28
16


10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.
William C Knowler, Sarah E Fowler, Richard F Hamman, Costas A Christophi, Heather J Hoffman, Anne T Brenneman, Janet O Brown-Friday, Ronald Goldberg, Elizabeth Venditti, David M Nathan. Lancet 2009
16

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Reut Yosef, Noam Pilpel, Ronit Tokarsky-Amiel, Anat Biran, Yossi Ovadya, Snir Cohen, Ezra Vadai, Liat Dassa, Elisheva Shahar, Reba Condiotti,[...]. Nat Commun 2016
355
16

TORC1 inhibition enhances immune function and reduces infections in the elderly.
Joan B Mannick, Melody Morris, Hans-Ulrich P Hockey, Guglielmo Roma, Martin Beibel, Kenneth Kulmatycki, Mollie Watkins, Tea Shavlakadze, Weihua Zhou, Dean Quinn,[...]. Sci Transl Med 2018
162
16

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.
Rhys Anderson, Anthony Lagnado, Damien Maggiorani, Anna Walaszczyk, Emily Dookun, James Chapman, Jodie Birch, Hanna Salmonowicz, Mikolaj Ogrodnik, Diana Jurk,[...]. EMBO J 2019
133
16

NF-κB inhibition delays DNA damage-induced senescence and aging in mice.
Jeremy S Tilstra, Andria R Robinson, Jin Wang, Siobhán Q Gregg, Cheryl L Clauson, Daniel P Reay, Luigi A Nasto, Claudette M St Croix, Arvydas Usas, Nam Vo,[...]. J Clin Invest 2012
261
16


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.