Anitha Saravanakumar, Armin Sadighi, Rachel Ryu, Fatemeh Akhlaghi. Clin Pharmacokinet 2019
Times Cited: 42
Times Cited: 42
Times Cited
Times Co-cited
Similarity
PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
40
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
35
Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
33
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
26
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
26
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
23
Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
38
The Evolution of PharmVar.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P Twist, Teri E Klein, Neil A Miller. Clin Pharmacol Ther 2019
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P Twist, Teri E Klein, Neil A Miller. Clin Pharmacol Ther 2019
23
CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.
Andrea Gaedigk, Amanda K Riffel, J Steven Leeder. J Mol Diagn 2015
Andrea Gaedigk, Amanda K Riffel, J Steven Leeder. J Mol Diagn 2015
34
CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
21
Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
21
CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.
Andrea Gaedigk, Uwe Fuhr, Charlene Johnson, L Anick Bérard, Dianne Bradford, J Steven Leeder. Pharmacogenomics 2010
Andrea Gaedigk, Uwe Fuhr, Charlene Johnson, L Anick Bérard, Dianne Bradford, J Steven Leeder. Pharmacogenomics 2010
21
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron.
G C Bell, K E Caudle, M Whirl-Carrillo, R J Gordon, K Hikino, C A Prows, A Gaedigk, Jag Agundez, S Sadhasivam, T E Klein,[...]. Clin Pharmacol Ther 2017
G C Bell, K E Caudle, M Whirl-Carrillo, R J Gordon, K Hikino, C A Prows, A Gaedigk, Jag Agundez, S Sadhasivam, T E Klein,[...]. Clin Pharmacol Ther 2017
19
The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
19
Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
16
Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
16
Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.
A Gaedigk, L Ndjountché, K Divakaran, L Dianne Bradford, I Zineh, T F Oberlander, D C Brousseau, D G McCarver, J A Johnson, S W Alander,[...]. Clin Pharmacol Ther 2007
A Gaedigk, L Ndjountché, K Divakaran, L Dianne Bradford, I Zineh, T F Oberlander, D C Brousseau, D G McCarver, J A Johnson, S W Alander,[...]. Clin Pharmacol Ther 2007
16
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
16
Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy.
Jacob T Brown, Jeffrey R Bishop, Katrin Sangkuhl, Erika L Nurmi, Daniel J Mueller, Jean C Dinh, Andrea Gaedigk, Teri E Klein, Kelly E Caudle, James T McCracken,[...]. Clin Pharmacol Ther 2019
Jacob T Brown, Jeffrey R Bishop, Katrin Sangkuhl, Erika L Nurmi, Daniel J Mueller, Jean C Dinh, Andrea Gaedigk, Teri E Klein, Kelly E Caudle, James T McCracken,[...]. Clin Pharmacol Ther 2019
16
16
Prediction of CYP2D6 phenotype from genotype across world populations.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
16
Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.
Lazara Karelia Montané Jaime, Anthony Lalla, Werner Steimer, Andrea Gaedigk. Pharmacogenomics 2013
Lazara Karelia Montané Jaime, Anthony Lalla, Werner Steimer, Andrea Gaedigk. Pharmacogenomics 2013
17
Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics.
Andrea Gaedigk, Jean C Dinh, Hyunyoung Jeong, Bhagwat Prasad, J Steven Leeder. J Pers Med 2018
Andrea Gaedigk, Jean C Dinh, Hyunyoung Jeong, Bhagwat Prasad, J Steven Leeder. J Pers Med 2018
14
Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization.
J Kevin Hicks, Jesse J Swen, Andrea Gaedigk. Curr Drug Metab 2014
J Kevin Hicks, Jesse J Swen, Andrea Gaedigk. Curr Drug Metab 2014
11
Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model.
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
12
Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.
Victoria M Pratt, Robin E Everts, Praful Aggarwal, Brittany N Beyer, Ulrich Broeckel, Ruth Epstein-Baak, Paul Hujsak, Ruth Kornreich, Jun Liao, Rachel Lorier,[...]. J Mol Diagn 2016
Victoria M Pratt, Robin E Everts, Praful Aggarwal, Brittany N Beyer, Ulrich Broeckel, Ruth Epstein-Baak, Paul Hujsak, Ruth Kornreich, Jun Liao, Rachel Lorier,[...]. J Mol Diagn 2016
11
Functional characterization of CYP2D6 enhancer polymorphisms.
Danxin Wang, Audrey C Papp, Xiaochun Sun. Hum Mol Genet 2015
Danxin Wang, Audrey C Papp, Xiaochun Sun. Hum Mol Genet 2015
11
Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology.
Victoria M Pratt, Andria L Del Tredici, Houda Hachad, Yuan Ji, Lisa V Kalman, Stuart A Scott, Karen E Weck. J Mol Diagn 2018
Victoria M Pratt, Andria L Del Tredici, Houda Hachad, Yuan Ji, Lisa V Kalman, Stuart A Scott, Karen E Weck. J Mol Diagn 2018
11
Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
11
Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
11
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.
Rachel Dalton, Seung-Been Lee, Katrina G Claw, Bhagwat Prasad, Brian R Phillips, Danny D Shen, Lai Hong Wong, Mitch Fade, Matthew G McDonald, Maitreya J Dunham,[...]. Clin Transl Sci 2020
Rachel Dalton, Seung-Been Lee, Katrina G Claw, Bhagwat Prasad, Brian R Phillips, Danny D Shen, Lai Hong Wong, Mitch Fade, Matthew G McDonald, Maitreya J Dunham,[...]. Clin Transl Sci 2020
26
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
11
A Review of the Important Role of CYP2D6 in Pharmacogenomics.
Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed, Richard M Turner. Genes (Basel) 2020
Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed, Richard M Turner. Genes (Basel) 2020
14
CYP2D6: novel genomic structures and alleles.
Whitney E Kramer, Denise L Walker, Dennis J O'Kane, David A Mrazek, Pamela K Fisher, Brian A Dukek, Jamie K Bruflat, John L Black. Pharmacogenet Genomics 2009
Whitney E Kramer, Denise L Walker, Dennis J O'Kane, David A Mrazek, Pamela K Fisher, Brian A Dukek, Jamie K Bruflat, John L Black. Pharmacogenet Genomics 2009
10
Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.
Wanqiong Qiao, Yao Yang, Robert Sebra, Geetu Mendiratta, Andrea Gaedigk, Robert J Desnick, Stuart A Scott. Hum Mutat 2016
Wanqiong Qiao, Yao Yang, Robert Sebra, Geetu Mendiratta, Andrea Gaedigk, Robert J Desnick, Stuart A Scott. Hum Mutat 2016
9
Flexible and Scalable Full-Length CYP2D6 Long Amplicon PacBio Sequencing.
Henk P J Buermans, Rolf H A M Vossen, Seyed Yahya Anvar, William G Allard, Henk-Jan Guchelaar, Stefan J White, Johan T den Dunnen, Jesse J Swen, Tahar van der Straaten. Hum Mutat 2017
Henk P J Buermans, Rolf H A M Vossen, Seyed Yahya Anvar, William G Allard, Henk-Jan Guchelaar, Stefan J White, Johan T den Dunnen, Jesse J Swen, Tahar van der Straaten. Hum Mutat 2017
12
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
L V Kalman, Jag Agúndez, M Lindqvist Appell, J L Black, G C Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A Coulthard,[...]. Clin Pharmacol Ther 2016
L V Kalman, Jag Agúndez, M Lindqvist Appell, J L Black, G C Bell, S Boukouvala, C Bruckner, E Bruford, K Caudle, S A Coulthard,[...]. Clin Pharmacol Ther 2016
9
Functional characterization of wild-type and 49 CYP2D6 allelic variants for N-desmethyltamoxifen 4-hydroxylation activity.
Yuka Muroi, Takahiro Saito, Masamitsu Takahashi, Kanako Sakuyama, Yui Niinuma, Miyabi Ito, Chiharu Tsukada, Kiminori Ohta, Yasuyuki Endo, Akifumi Oda,[...]. Drug Metab Pharmacokinet 2014
Yuka Muroi, Takahiro Saito, Masamitsu Takahashi, Kanako Sakuyama, Yui Niinuma, Miyabi Ito, Chiharu Tsukada, Kiminori Ohta, Yasuyuki Endo, Akifumi Oda,[...]. Drug Metab Pharmacokinet 2014
12
Quantification of In Vivo Metabolic Activity of CYP2D6 Genotypes and Alleles Through Population Pharmacokinetic Analysis of Vortioxetine.
Trine Frederiksen, Johan Areberg, Ellen Schmidt, Tore Bjerregaard Stage, Kim Brøsen. Clin Pharmacol Ther 2021
Trine Frederiksen, Johan Areberg, Ellen Schmidt, Tore Bjerregaard Stage, Kim Brøsen. Clin Pharmacol Ther 2021
50
Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
9
Accurately genotyping CYP2D6: not for the faint of heart.
Charity Nofziger, Markus Paulmichl. Pharmacogenomics 2018
Charity Nofziger, Markus Paulmichl. Pharmacogenomics 2018
21
Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015.
Matthew A Cerny. Drug Metab Dispos 2016
Matthew A Cerny. Drug Metab Dispos 2016
9
PharmVar GeneFocus: CYP2C19.
Mariana R Botton, Michelle Whirl-Carrillo, Andria L Del Tredici, Katrin Sangkuhl, Larisa H Cavallari, José A G Agúndez, Jorge Duconge, Ming Ta Michael Lee, Erica L Woodahl, Karla Claudio-Campos,[...]. Clin Pharmacol Ther 2021
Mariana R Botton, Michelle Whirl-Carrillo, Andria L Del Tredici, Katrin Sangkuhl, Larisa H Cavallari, José A G Agúndez, Jorge Duconge, Ming Ta Michael Lee, Erica L Woodahl, Karla Claudio-Campos,[...]. Clin Pharmacol Ther 2021
19
CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
7
Frequency of CYP2D6 Alleles Including Structural Variants in the United States.
Andria L Del Tredici, Alka Malhotra, Matthew Dedek, Frank Espin, Dan Roach, Guang-Dan Zhu, Joseph Voland, Tanya A Moreno. Front Pharmacol 2018
Andria L Del Tredici, Alka Malhotra, Matthew Dedek, Frank Espin, Dan Roach, Guang-Dan Zhu, Joseph Voland, Tanya A Moreno. Front Pharmacol 2018
7
Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
7
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
Hongwu Shen, Minxia M He, Houfu Liu, Steven A Wrighton, Li Wang, Bin Guo, Chuan Li. Drug Metab Dispos 2007
Hongwu Shen, Minxia M He, Houfu Liu, Steven A Wrighton, Li Wang, Bin Guo, Chuan Li. Drug Metab Dispos 2007
7
Frequency of undetected CYP2D6 hybrid genes in clinical samples: impact on phenotype prediction.
John Logan Black, Denise L Walker, Dennis J O'Kane, Maria Harmandayan. Drug Metab Dispos 2012
John Logan Black, Denise L Walker, Dennis J O'Kane, Maria Harmandayan. Drug Metab Dispos 2012
7
Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations.
Andrea Gaedigk, Maria Isidoro-García, Robin E Pearce, Santiago Sánchez, Virginia García-Solaesa, Carolina Lorenzo-Romo, Gloria Gonzalez-Tejera, Susan Corey. Eur J Clin Pharmacol 2010
Andrea Gaedigk, Maria Isidoro-García, Robin E Pearce, Santiago Sánchez, Virginia García-Solaesa, Carolina Lorenzo-Romo, Gloria Gonzalez-Tejera, Susan Corey. Eur J Clin Pharmacol 2010
12
Detection and characterization of the CYP2D6*9x2 gene duplication in two Spanish populations: resolution of AmpliChip CYP450 test no-calls.
Andrea Gaedigk, Juanjo Hernandez, Virginia García-Solaesa, Santiago Sánchez, Maria Isidoro-García. Pharmacogenomics 2011
Andrea Gaedigk, Juanjo Hernandez, Virginia García-Solaesa, Santiago Sánchez, Maria Isidoro-García. Pharmacogenomics 2011
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.