Rui Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan, Kara L Gordon, Jeffrey Snowden, Subo Yuan, Audrey S Dickey, Sanjeev Choudhary, Tetsuo Ashizawa, Lisa M Ellerby, Albert R La Spada, Leslie M Thompson, Tapas K Hazra, Partha S Sarkar. Elife 2019
Times Cited: 44
Times Cited: 44
Times Cited
Times Co-cited
Similarity
Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.
Tamara Maiuri, Andrew J Mocle, Claudia L Hung, Jianrun Xia, Willeke M C van Roon-Mom, Ray Truant. Hum Mol Genet 2017
Tamara Maiuri, Andrew J Mocle, Claudia L Hung, Jianrun Xia, Willeke M C van Roon-Mom, Ray Truant. Hum Mol Genet 2017
36
Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3.
Rui Gao, Yongping Liu, Anabela Silva-Fernandes, Xiang Fang, Adriana Paulucci-Holthauzen, Arpita Chatterjee, Hang L Zhang, Tohru Matsuura, Sanjeev Choudhary, Tetsuo Ashizawa,[...]. PLoS Genet 2015
Rui Gao, Yongping Liu, Anabela Silva-Fernandes, Xiang Fang, Adriana Paulucci-Holthauzen, Arpita Chatterjee, Hang L Zhang, Tohru Matsuura, Sanjeev Choudhary, Tetsuo Ashizawa,[...]. PLoS Genet 2015
29
27
DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases.
Conceição Bettencourt, Davina Hensman-Moss, Michael Flower, Sarah Wiethoff, Alexis Brice, Cyril Goizet, Giovanni Stevanin, Georgios Koutsis, Georgia Karadima, Marios Panas,[...]. Ann Neurol 2016
Conceição Bettencourt, Davina Hensman-Moss, Michael Flower, Sarah Wiethoff, Alexis Brice, Cyril Goizet, Giovanni Stevanin, Georgios Koutsis, Georgia Karadima, Marios Panas,[...]. Ann Neurol 2016
25
25
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
Arpita Chatterjee, Saikat Saha, Anirban Chakraborty, Anabela Silva-Fernandes, Santi M Mandal, Andreia Neves-Carvalho, Yongping Liu, Raj K Pandita, Muralidhar L Hegde, Pavana M Hegde,[...]. PLoS Genet 2015
Arpita Chatterjee, Saikat Saha, Anirban Chakraborty, Anabela Silva-Fernandes, Santi M Mandal, Andreia Neves-Carvalho, Yongping Liu, Raj K Pandita, Muralidhar L Hegde, Pavana M Hegde,[...]. PLoS Genet 2015
22
22
DNA Damage Repair in Huntington's Disease and Other Neurodegenerative Diseases.
T Maiuri, C E Suart, C L K Hung, K J Graham, C A Barba Bazan, R Truant. Neurotherapeutics 2019
T Maiuri, C E Suart, C L K Hung, K J Graham, C A Barba Bazan, R Truant. Neurotherapeutics 2019
33
Mutant huntingtin impairs Ku70-mediated DNA repair.
Yasushi Enokido, Takuya Tamura, Hikaru Ito, Anup Arumughan, Akihiko Komuro, Hiroki Shiwaku, Masaki Sone, Raphaele Foulle, Hirohide Sawada, Hiroshi Ishiguro,[...]. J Cell Biol 2010
Yasushi Enokido, Takuya Tamura, Hikaru Ito, Anup Arumughan, Akihiko Komuro, Hiroki Shiwaku, Masaki Sone, Raphaele Foulle, Hirohide Sawada, Hiroshi Ishiguro,[...]. J Cell Biol 2010
20
DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates.
Jennifer Illuzzi, Sarah Yerkes, Hetal Parekh-Olmedo, Eric B Kmiec. J Neurosci Res 2009
Jennifer Illuzzi, Sarah Yerkes, Hetal Parekh-Olmedo, Eric B Kmiec. J Neurosci Res 2009
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The central role of DNA damage and repair in CAG repeat diseases.
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
18
Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
18
Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.
Annika Pfeiffer, Martijn S Luijsterburg, Klara Acs, Wouter W Wiegant, Angela Helfricht, Laura K Herzog, Melania Minoia, Claudia Böttcher, Florian A Salomons, Haico van Attikum,[...]. EMBO J 2017
Annika Pfeiffer, Martijn S Luijsterburg, Klara Acs, Wouter W Wiegant, Angela Helfricht, Laura K Herzog, Melania Minoia, Claudia Böttcher, Florian A Salomons, Haico van Attikum,[...]. EMBO J 2017
16
FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.
Robert Goold, Michael Flower, Davina Hensman Moss, Chris Medway, Alison Wood-Kaczmar, Ralph Andre, Pamela Farshim, Gill P Bates, Peter Holmans, Lesley Jones,[...]. Hum Mol Genet 2019
Robert Goold, Michael Flower, Davina Hensman Moss, Chris Medway, Alison Wood-Kaczmar, Ralph Andre, Pamela Farshim, Gill P Bates, Peter Holmans, Lesley Jones,[...]. Hum Mol Genet 2019
15
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.
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15
Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes.
Anirban Chakraborty, Nisha Tapryal, Tatiana Venkova, Nobuo Horikoshi, Raj K Pandita, Altaf H Sarker, Partha S Sarkar, Tej K Pandita, Tapas K Hazra. Nat Commun 2016
Anirban Chakraborty, Nisha Tapryal, Tatiana Venkova, Nobuo Horikoshi, Raj K Pandita, Altaf H Sarker, Partha S Sarkar, Tej K Pandita, Tapas K Hazra. Nat Commun 2016
15
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Nicolas C Hoch, Hana Hanzlikova, Stuart L Rulten, Martine Tétreault, Emilia Komulainen, Limei Ju, Peter Hornyak, Zhihong Zeng, William Gittens, Stephanie A Rey,[...]. Nature 2017
Nicolas C Hoch, Hana Hanzlikova, Stuart L Rulten, Martine Tétreault, Emilia Komulainen, Limei Ju, Peter Hornyak, Zhihong Zeng, William Gittens, Stephanie A Rey,[...]. Nature 2017
13
DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage.
Tamara Maiuri, Laura E Bowie, Ray Truant. DNA Cell Biol 2019
Tamara Maiuri, Laura E Bowie, Ray Truant. DNA Cell Biol 2019
46
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients.
Georgina Askeland, Zaneta Dosoudilova, Marie Rodinova, Jiri Klempir, Irena Liskova, Anna Kuśnierczyk, Magnar Bjørås, Gaute Nesse, Arne Klungland, Hana Hansikova,[...]. Sci Rep 2018
Georgina Askeland, Zaneta Dosoudilova, Marie Rodinova, Jiri Klempir, Irena Liskova, Anna Kuśnierczyk, Magnar Bjørås, Gaute Nesse, Arne Klungland, Hana Hansikova,[...]. Sci Rep 2018
27
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Davina J Hensman Moss, Antonio F Pardiñas, Douglas Langbehn, Kitty Lo, Blair R Leavitt, Raymund Roos, Alexandra Durr, Simon Mead, Peter Holmans, Lesley Jones,[...]. Lancet Neurol 2017
Davina J Hensman Moss, Antonio F Pardiñas, Douglas Langbehn, Kitty Lo, Blair R Leavitt, Raymund Roos, Alexandra Durr, Simon Mead, Peter Holmans, Lesley Jones,[...]. Lancet Neurol 2017
13
Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.
Mélanie L Ferlazzo, Laurène Sonzogni, Adeline Granzotto, Larry Bodgi, Océane Lartin, Clément Devic, Guillaume Vogin, Sandrine Pereira, Nicolas Foray. Mol Neurobiol 2014
Mélanie L Ferlazzo, Laurène Sonzogni, Adeline Granzotto, Larry Bodgi, Océane Lartin, Clément Devic, Guillaume Vogin, Sandrine Pereira, Nicolas Foray. Mol Neurobiol 2014
13
Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease.
Chiara Milanese, Silvia Cerri, Ayse Ulusoy, Simona V Gornati, Audrey Plat, Sylvia Gabriels, Fabio Blandini, Donato A Di Monte, Jan H Hoeijmakers, Pier G Mastroberardino. Cell Death Dis 2018
Chiara Milanese, Silvia Cerri, Ayse Ulusoy, Simona V Gornati, Audrey Plat, Sylvia Gabriels, Fabio Blandini, Donato A Di Monte, Jan H Hoeijmakers, Pier G Mastroberardino. Cell Death Dis 2018
13
Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease.
Niraj M Shanbhag, Mark D Evans, Wenjie Mao, Alissa L Nana, William W Seeley, Anthony Adame, Robert A Rissman, Eliezer Masliah, Lennart Mucke. Acta Neuropathol Commun 2019
Niraj M Shanbhag, Mark D Evans, Wenjie Mao, Alissa L Nana, William W Seeley, Anthony Adame, Robert A Rissman, Eliezer Masliah, Lennart Mucke. Acta Neuropathol Commun 2019
13
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
13
13
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
13
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Joy Mitra, Erika N Guerrero, Pavana M Hegde, Nicole F Liachko, Haibo Wang, Velmarini Vasquez, Junling Gao, Arvind Pandey, J Paul Taylor, Brian C Kraemer,[...]. Proc Natl Acad Sci U S A 2019
Joy Mitra, Erika N Guerrero, Pavana M Hegde, Nicole F Liachko, Haibo Wang, Velmarini Vasquez, Junling Gao, Arvind Pandey, J Paul Taylor, Brian C Kraemer,[...]. Proc Natl Acad Sci U S A 2019
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A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
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Disease-associated repeat instability and mismatch repair.
Monika H M Schmidt, Christopher E Pearson. DNA Repair (Amst) 2016
Monika H M Schmidt, Christopher E Pearson. DNA Repair (Amst) 2016
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Mutations in PNKP cause microcephaly, seizures and defects in DNA repair.
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CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
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Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
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DNA repair in the trinucleotide repeat disorders.
Lesley Jones, Henry Houlden, Sarah J Tabrizi. Lancet Neurol 2017
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Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair.
John J Reynolds, Alexandra K Walker, Edward C Gilmore, Christopher A Walsh, Keith W Caldecott. Nucleic Acids Res 2012
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Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Elsa Suberbielle, Pascal E Sanchez, Alexxai V Kravitz, Xin Wang, Kaitlyn Ho, Kirsten Eilertson, Nino Devidze, Anatol C Kreitzer, Lennart Mucke. Nat Neurosci 2013
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11
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
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The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Erich E Wanker, Anne Ast, Franziska Schindler, Philipp Trepte, Sigrid Schnoegl. J Neurochem 2019
Erich E Wanker, Anne Ast, Franziska Schindler, Philipp Trepte, Sigrid Schnoegl. J Neurochem 2019
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A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes.
Marc Ciosi, Alastair Maxwell, Sarah A Cumming, Davina J Hensman Moss, Asma M Alshammari, Michael D Flower, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Peter Holmans,[...]. EBioMedicine 2019
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11
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
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Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders.
Allison J Schaser, Valerie R Osterberg, Sydney E Dent, Teresa L Stackhouse, Colin M Wakeham, Sydney W Boutros, Leah J Weston, Nichole Owen, Tamily A Weissman, Esteban Luna,[...]. Sci Rep 2019
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Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.
Wen-Yuan Wang, Ling Pan, Susan C Su, Emma J Quinn, Megumi Sasaki, Jessica C Jimenez, Ian R A Mackenzie, Eric J Huang, Li-Huei Tsai. Nat Neurosci 2013
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Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
Anirban Chakraborty, Nisha Tapryal, Tatiana Venkova, Joy Mitra, Velmarini Vasquez, Altaf H Sarker, Sara Duarte-Silva, Weihan Huai, Tetsuo Ashizawa, Gourisankar Ghosh,[...]. Proc Natl Acad Sci U S A 2020
Anirban Chakraborty, Nisha Tapryal, Tatiana Venkova, Joy Mitra, Velmarini Vasquez, Altaf H Sarker, Sara Duarte-Silva, Weihan Huai, Tetsuo Ashizawa, Gourisankar Ghosh,[...]. Proc Natl Acad Sci U S A 2020
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Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
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The cryo-electron microscopy structure of huntingtin.
Qiang Guo, Bin Huang, Jingdong Cheng, Manuel Seefelder, Tatjana Engler, Günter Pfeifer, Patrick Oeckl, Markus Otto, Franziska Moser, Melanie Maurer,[...]. Nature 2018
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Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.
Lior Weissman, Dong-Gyu Jo, Martin M Sørensen, Nadja C de Souza-Pinto, William R Markesbery, Mark P Mattson, Vilhelm A Bohr. Nucleic Acids Res 2007
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Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain.
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
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9
Kinase inhibitors modulate huntingtin cell localization and toxicity.
Randy Singh Atwal, Carly R Desmond, Nicholas Caron, Tamara Maiuri, Jianrun Xia, Simonetta Sipione, Ray Truant. Nat Chem Biol 2011
Randy Singh Atwal, Carly R Desmond, Nicholas Caron, Tamara Maiuri, Jianrun Xia, Simonetta Sipione, Ray Truant. Nat Chem Biol 2011
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DNA damage signatures in peripheral blood cells as biomarkers in prodromal huntington disease.
Imma Castaldo, Mariarosaria De Rosa, Antonella Romano, Candida Zuchegna, Ferdinando Squitieri, Rosella Mechelli, Silvio Peluso, Cristiana Borrelli, Angelo Del Mondo, Elena Salvatore,[...]. Ann Neurol 2019
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28
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.