Toby Lieber, Swathi P Jeedigunta, Jonathan M Palozzi, Ruth Lehmann, Thomas R Hurd. Nature 2019
Times Cited: 81
Times Cited: 81
Times Cited
Times Co-cited
Similarity
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.
Vasileios I Floros, Angela Pyle, Sabine Dietmann, Wei Wei, Walfred C W Tang, Naoko Irie, Brendan Payne, Antonio Capalbo, Laila Noli, Jonathan Coxhead,[...]. Nat Cell Biol 2018
Vasileios I Floros, Angela Pyle, Sabine Dietmann, Wei Wei, Walfred C W Tang, Naoko Irie, Brendan Payne, Antonio Capalbo, Laila Noli, Jonathan Coxhead,[...]. Nat Cell Biol 2018
24
Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant.
Jahda H Hill, Zhe Chen, Hong Xu. Nat Genet 2014
Jahda H Hill, Zhe Chen, Hong Xu. Nat Genet 2014
24
A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.
Weiwei Fan, Katrina G Waymire, Navneet Narula, Peng Li, Christophe Rocher, Pinar E Coskun, Mani A Vannan, Jagat Narula, Grant R Macgregor, Douglas C Wallace. Science 2008
Weiwei Fan, Katrina G Waymire, Navneet Narula, Peng Li, Christophe Rocher, Pinar E Coskun, Mani A Vannan, Jagat Narula, Grant R Macgregor, Douglas C Wallace. Science 2008
24
Strong purifying selection in transmission of mammalian mitochondrial DNA.
James Bruce Stewart, Christoph Freyer, Joanna L Elson, Anna Wredenberg, Zekiye Cansu, Aleksandra Trifunovic, Nils-Göran Larsson. PLoS Biol 2008
James Bruce Stewart, Christoph Freyer, Joanna L Elson, Anna Wredenberg, Zekiye Cansu, Aleksandra Trifunovic, Nils-Göran Larsson. PLoS Biol 2008
23
The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.
James B Stewart, Patrick F Chinnery. Nat Rev Genet 2015
James B Stewart, Patrick F Chinnery. Nat Rev Genet 2015
19
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes.
Timothy Wai, Daniella Teoli, Eric A Shoubridge. Nat Genet 2008
Timothy Wai, Daniella Teoli, Eric A Shoubridge. Nat Genet 2008
19
Germline selection shapes human mitochondrial DNA diversity.
Wei Wei, Salih Tuna, Michael J Keogh, Katherine R Smith, Timothy J Aitman, Phil L Beales, David L Bennett, Daniel P Gale, Maria A K Bitner-Glindzicz, Graeme C Black,[...]. Science 2019
Wei Wei, Salih Tuna, Michael J Keogh, Katherine R Smith, Timothy J Aitman, Phil L Beales, David L Bennett, Daniel P Gale, Maria A K Bitner-Glindzicz, Graeme C Black,[...]. Science 2019
19
PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations.
Yi Zhang, Zong-Heng Wang, Yi Liu, Yong Chen, Nuo Sun, Marjan Gucek, Fan Zhang, Hong Xu. Mol Cell 2019
Yi Zhang, Zong-Heng Wang, Yi Liu, Yong Chen, Nuo Sun, Marjan Gucek, Fan Zhang, Hong Xu. Mol Cell 2019
45
Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
Yi-Fan Lin, Anna M Schulz, Mark W Pellegrino, Yun Lu, Shai Shaham, Cole M Haynes. Nature 2016
Yi-Fan Lin, Anna M Schulz, Mark W Pellegrino, Yun Lu, Shai Shaham, Cole M Haynes. Nature 2016
17
Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition.
Mark S Sharpley, Christine Marciniak, Kristin Eckel-Mahan, Meagan McManus, Marco Crimi, Katrina Waymire, Chun Shi Lin, Satoru Masubuchi, Nicole Friend, Maya Koike,[...]. Cell 2012
Mark S Sharpley, Christine Marciniak, Kristin Eckel-Mahan, Meagan McManus, Marco Crimi, Katrina Waymire, Chun Shi Lin, Satoru Masubuchi, Nicole Friend, Maya Koike,[...]. Cell 2012
16
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes.
Lynsey M Cree, David C Samuels, Susana Chuva de Sousa Lopes, Harsha Karur Rajasimha, Passorn Wonnapinij, Jeffrey R Mann, Hans-Henrik M Dahl, Patrick F Chinnery. Nat Genet 2008
Lynsey M Cree, David C Samuels, Susana Chuva de Sousa Lopes, Harsha Karur Rajasimha, Passorn Wonnapinij, Jeffrey R Mann, Hans-Henrik M Dahl, Patrick F Chinnery. Nat Genet 2008
16
Transmission of mitochondrial mutations and action of purifying selection in Drosophila melanogaster.
Hansong Ma, Hong Xu, Patrick H O'Farrell. Nat Genet 2014
Hansong Ma, Hong Xu, Patrick H O'Farrell. Nat Genet 2014
20
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission.
Christoph Freyer, Lynsey M Cree, Arnaud Mourier, James B Stewart, Camilla Koolmeister, Dusanka Milenkovic, Timothy Wai, Vasileios I Floros, Erik Hagström, Emmanouella E Chatzidaki,[...]. Nat Genet 2012
Christoph Freyer, Lynsey M Cree, Arnaud Mourier, James B Stewart, Camilla Koolmeister, Dusanka Milenkovic, Timothy Wai, Vasileios I Floros, Erik Hagström, Emmanouella E Chatzidaki,[...]. Nat Genet 2012
16
ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Samantha C Lewis, Lauren F Uchiyama, Jodi Nunnari. Science 2016
Samantha C Lewis, Lauren F Uchiyama, Jodi Nunnari. Science 2016
14
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
14
A Balbiani body and the fusome mediate mitochondrial inheritance during Drosophila oogenesis.
Rachel T Cox, Allan C Spradling. Development 2003
Rachel T Cox, Allan C Spradling. Development 2003
14
Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease.
Gráinne S Gorman, Andrew M Schaefer, Yi Ng, Nicholas Gomez, Emma L Blakely, Charlotte L Alston, Catherine Feeney, Rita Horvath, Patrick Yu-Wai-Man, Patrick F Chinnery,[...]. Ann Neurol 2015
Gráinne S Gorman, Andrew M Schaefer, Yi Ng, Nicholas Gomez, Emma L Blakely, Charlotte L Alston, Catherine Feeney, Rita Horvath, Patrick Yu-Wai-Man, Patrick F Chinnery,[...]. Ann Neurol 2015
14
Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1.
Rebecca Rojansky, Moon-Yong Cha, David C Chan. Elife 2016
Rebecca Rojansky, Moon-Yong Cha, David C Chan. Elife 2016
13
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells.
Der-Fen Suen, Derek P Narendra, Atsushi Tanaka, Giovanni Manfredi, Richard J Youle. Proc Natl Acad Sci U S A 2010
Der-Fen Suen, Derek P Narendra, Atsushi Tanaka, Giovanni Manfredi, Richard J Youle. Proc Natl Acad Sci U S A 2010
12
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
12
Universal heteroplasmy of human mitochondrial DNA.
Brendan A I Payne, Ian J Wilson, Patrick Yu-Wai-Man, Jonathan Coxhead, David Deehan, Rita Horvath, Robert W Taylor, David C Samuels, Mauro Santibanez-Koref, Patrick F Chinnery. Hum Mol Genet 2013
Brendan A I Payne, Ian J Wilson, Patrick Yu-Wai-Man, Jonathan Coxhead, David Deehan, Rita Horvath, Robert W Taylor, David C Samuels, Mauro Santibanez-Koref, Patrick F Chinnery. Hum Mol Genet 2013
12
Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
12
Selfish drive can trump function when animal mitochondrial genomes compete.
Hansong Ma, Patrick H O'Farrell. Nat Genet 2016
Hansong Ma, Patrick H O'Farrell. Nat Genet 2016
25
Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.
J P Jenuth, A C Peterson, K Fu, E A Shoubridge. Nat Genet 1996
J P Jenuth, A C Peterson, K Fu, E A Shoubridge. Nat Genet 1996
12
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission.
Sara Al Rawi, Sophie Louvet-Vallée, Abderazak Djeddi, Martin Sachse, Emmanuel Culetto, Connie Hajjar, Lynn Boyd, Renaud Legouis, Vincent Galy. Science 2011
Sara Al Rawi, Sophie Louvet-Vallée, Abderazak Djeddi, Martin Sachse, Emmanuel Culetto, Connie Hajjar, Lynn Boyd, Renaud Legouis, Vincent Galy. Science 2011
12
ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
12
Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.
Bryan L Gitschlag, Cait S Kirby, David C Samuels, Rama D Gangula, Simon A Mallal, Maulik R Patel. Cell Metab 2016
Bryan L Gitschlag, Cait S Kirby, David C Samuels, Rama D Gangula, Simon A Mallal, Maulik R Patel. Cell Metab 2016
12
Long Oskar Controls Mitochondrial Inheritance in Drosophila melanogaster.
Thomas Ryan Hurd, Beate Herrmann, Julia Sauerwald, Justina Sanny, Markus Grosch, Ruth Lehmann. Dev Cell 2016
Thomas Ryan Hurd, Beate Herrmann, Julia Sauerwald, Justina Sanny, Markus Grosch, Ruth Lehmann. Dev Cell 2016
21
Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.
Douglas C Wallace, Dimitra Chalkia. Cold Spring Harb Perspect Biol 2013
Douglas C Wallace, Dimitra Chalkia. Cold Spring Harb Perspect Biol 2013
11
Biparental Inheritance of Mitochondrial DNA in Humans.
Shiyu Luo, C Alexander Valencia, Jinglan Zhang, Ni-Chung Lee, Jesse Slone, Baoheng Gui, Xinjian Wang, Zhuo Li, Sarah Dell, Jenice Brown,[...]. Proc Natl Acad Sci U S A 2018
Shiyu Luo, C Alexander Valencia, Jinglan Zhang, Ni-Chung Lee, Jesse Slone, Baoheng Gui, Xinjian Wang, Zhuo Li, Sarah Dell, Jenice Brown,[...]. Proc Natl Acad Sci U S A 2018
11
Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
11
Degradation of paternal mitochondria by fertilization-triggered autophagy in C. elegans embryos.
Miyuki Sato, Ken Sato. Science 2011
Miyuki Sato, Ken Sato. Science 2011
11
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
11
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
11
Paternal mitochondrial destruction after fertilization is mediated by a common endocytic and autophagic pathway in Drosophila.
Yoav Politi, Liron Gal, Yossi Kalifa, Liat Ravid, Zvulun Elazar, Eli Arama. Dev Cell 2014
Yoav Politi, Liron Gal, Yossi Kalifa, Liat Ravid, Zvulun Elazar, Eli Arama. Dev Cell 2014
11
Mitochondrial DNA polymorphism in a maternal lineage of Holstein cows.
W W Hauswirth, P J Laipis. Proc Natl Acad Sci U S A 1982
W W Hauswirth, P J Laipis. Proc Natl Acad Sci U S A 1982
11
Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.
Ana Latorre-Pellicer, Ana Victoria Lechuga-Vieco, Iain G Johnston, Riikka H Hämäläinen, Juan Pellico, Raquel Justo-Méndez, Jose María Fernández-Toro, Cristina Clavería, Adela Guaras, Rocío Sierra,[...]. Cell Metab 2019
Ana Latorre-Pellicer, Ana Victoria Lechuga-Vieco, Iain G Johnston, Riikka H Hämäläinen, Juan Pellico, Raquel Justo-Méndez, Jose María Fernández-Toro, Cristina Clavería, Adela Guaras, Rocío Sierra,[...]. Cell Metab 2019
23
Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila.
Nikolay P Kandul, Ting Zhang, Bruce A Hay, Ming Guo. Nat Commun 2016
Nikolay P Kandul, Ting Zhang, Bruce A Hay, Ming Guo. Nat Commun 2016
18
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.
Hsiuchen Chen, Marc Vermulst, Yun E Wang, Anne Chomyn, Tomas A Prolla, J Michael McCaffery, David C Chan. Cell 2010
Hsiuchen Chen, Marc Vermulst, Yun E Wang, Anne Chomyn, Tomas A Prolla, J Michael McCaffery, David C Chan. Cell 2010
9
Mitochondrial DNA Purifying Selection in Mammals and Invertebrates.
Jonathan M Palozzi, Swathi P Jeedigunta, Thomas R Hurd. J Mol Biol 2018
Jonathan M Palozzi, Swathi P Jeedigunta, Thomas R Hurd. J Mol Biol 2018
44
Stable heteroplasmy but differential inheritance of a large mitochondrial DNA deletion in nematodes.
William Y Tsang, Bernard D Lemire. Biochem Cell Biol 2002
William Y Tsang, Bernard D Lemire. Biochem Cell Biol 2002
13
Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease.
James Bruce Stewart, Christoph Freyer, Joanna L Elson, Nils-Göran Larsson. Nat Rev Genet 2008
James Bruce Stewart, Christoph Freyer, Joanna L Elson, Nils-Göran Larsson. Nat Rev Genet 2008
9
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle. Neuron 2015
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle. Neuron 2015
9
A vesicular transport pathway shuttles cargo from mitochondria to lysosomes.
Vincent Soubannier, Gian-Luca McLelland, Rodolfo Zunino, Emelie Braschi, Peter Rippstein, Edward A Fon, Heidi M McBride. Curr Biol 2012
Vincent Soubannier, Gian-Luca McLelland, Rodolfo Zunino, Emelie Braschi, Peter Rippstein, Edward A Fon, Heidi M McBride. Curr Biol 2012
9
Mitochondrial fission facilitates the selective mitophagy of protein aggregates.
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
Jonathon L Burman, Sarah Pickles, Chunxin Wang, Shiori Sekine, Jose Norberto S Vargas, Zhe Zhang, Alice M Youle, Catherine L Nezich, Xufeng Wu, John A Hammer,[...]. J Cell Biol 2017
9
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells.
Liqin Cao, Hiroshi Shitara, Takuro Horii, Yasumitsu Nagao, Hiroshi Imai, Kuniya Abe, Takahiko Hara, Jun-Ichi Hayashi, Hiromichi Yonekawa. Nat Genet 2007
Liqin Cao, Hiroshi Shitara, Takuro Horii, Yasumitsu Nagao, Hiroshi Imai, Kuniya Abe, Takahiko Hara, Jun-Ichi Hayashi, Hiromichi Yonekawa. Nat Genet 2007
9
Mitochondrial diseases.
Gráinne S Gorman, Patrick F Chinnery, Salvatore DiMauro, Michio Hirano, Yasutoshi Koga, Robert McFarland, Anu Suomalainen, David R Thorburn, Massimo Zeviani, Douglass M Turnbull. Nat Rev Dis Primers 2016
Gráinne S Gorman, Patrick F Chinnery, Salvatore DiMauro, Michio Hirano, Yasutoshi Koga, Robert McFarland, Anu Suomalainen, David R Thorburn, Massimo Zeviani, Douglass M Turnbull. Nat Rev Dis Primers 2016
8
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
8
Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.