Nicholas G Fox, Xiaodi Yu, Xidong Feng, Henry J Bailey, Alain Martelli, Joseph F Nabhan, Claire Strain-Damerell, Christine Bulawa, Wyatt W Yue, Seungil Han. Nat Commun 2019
Times Cited: 63
Times Cited: 63
Times Cited
Times Co-cited
Similarity
Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Michal T Boniecki, Sven A Freibert, Ulrich Mühlenhoff, Roland Lill, Miroslaw Cygler. Nat Commun 2017
Michal T Boniecki, Sven A Freibert, Ulrich Mühlenhoff, Roland Lill, Miroslaw Cygler. Nat Commun 2017
50
Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin.
Sylvain Gervason, Djabir Larkem, Amir Ben Mansour, Thomas Botzanowski, Christina S Müller, Ludovic Pecqueur, Gwenaelle Le Pavec, Agnès Delaunay-Moisan, Omar Brun, Jordi Agramunt,[...]. Nat Commun 2019
Sylvain Gervason, Djabir Larkem, Amir Ben Mansour, Thomas Botzanowski, Christina S Müller, Ludovic Pecqueur, Gwenaelle Le Pavec, Agnès Delaunay-Moisan, Omar Brun, Jordi Agramunt,[...]. Nat Commun 2019
48
Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
Seth A Cory, Jonathan G Van Vranken, Edward J Brignole, Shachin Patra, Dennis R Winge, Catherine L Drennan, Jared Rutter, David P Barondeau. Proc Natl Acad Sci U S A 2017
Seth A Cory, Jonathan G Van Vranken, Edward J Brignole, Shachin Patra, Dennis R Winge, Catherine L Drennan, Jared Rutter, David P Barondeau. Proc Natl Acad Sci U S A 2017
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Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry.
Jennifer Bridwell-Rabb, Nicholas G Fox, Chi-Lin Tsai, Andrew M Winn, David P Barondeau. Biochemistry 2014
Jennifer Bridwell-Rabb, Nicholas G Fox, Chi-Lin Tsai, Andrew M Winn, David P Barondeau. Biochemistry 2014
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Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols.
Aubérie Parent, Xavier Elduque, David Cornu, Laura Belot, Jean-Pierre Le Caer, Anna Grandas, Michel B Toledano, Benoit D'Autréaux. Nat Commun 2015
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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion.
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The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis.
Jonathan G Van Vranken, Mi-Young Jeong, Peng Wei, Yu-Chan Chen, Steven P Gygi, Dennis R Winge, Jared Rutter. Elife 2016
Jonathan G Van Vranken, Mi-Young Jeong, Peng Wei, Yu-Chan Chen, Steven P Gygi, Dennis R Winge, Jared Rutter. Elife 2016
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The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria.
Alexander C Adam, Carsten Bornhövd, Holger Prokisch, Walter Neupert, Kai Hell. EMBO J 2006
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Iron-sulfur cluster biogenesis and trafficking in mitochondria.
Joseph J Braymer, Roland Lill. J Biol Chem 2017
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Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex.
Chi-Lin Tsai, David P Barondeau. Biochemistry 2010
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Mechanism of activation of the human cysteine desulfurase complex by frataxin.
Shachin Patra, David P Barondeau. Proc Natl Acad Sci U S A 2019
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Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.
Stéphane Schmucker, Alain Martelli, Florent Colin, Adeline Page, Marie Wattenhofer-Donzé, Laurence Reutenauer, Hélène Puccio. PLoS One 2011
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Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins.
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Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin.
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A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins.
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The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation.
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Crystal structure of human frataxin.
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Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits.
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Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p.
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Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins.
Ulrich Mühlenhoff, Nadine Richter, Ophry Pines, Antonio J Pierik, Roland Lill. J Biol Chem 2011
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Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes.
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Compound heterozygous FXN mutations and clinical outcome in friedreich ataxia.
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Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery.
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Molecular chaperones HscA/Ssq1 and HscB/Jac1 and their roles in iron-sulfur protein maturation.
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The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins.
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Structure, function, and formation of biological iron-sulfur clusters.
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Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly.
Kai Cai, Ronnie O Frederick, Marco Tonelli, John L Markley. J Inorg Biochem 2018
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Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes.
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Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery.
Nunziata Maio, Anamika Singh, Helge Uhrigshardt, Neetu Saxena, Wing-Hang Tong, Tracey A Rouault. Cell Metab 2014
Nunziata Maio, Anamika Singh, Helge Uhrigshardt, Neetu Saxena, Wing-Hang Tong, Tracey A Rouault. Cell Metab 2014
17
ACP Acylation Is an Acetyl-CoA-Dependent Modification Required for Electron Transport Chain Assembly.
Jonathan G Van Vranken, Sara M Nowinski, Katie J Clowers, Mi-Young Jeong, Yeyun Ouyang, Jordan A Berg, Jeremy P Gygi, Steven P Gygi, Dennis R Winge, Jared Rutter. Mol Cell 2018
Jonathan G Van Vranken, Sara M Nowinski, Katie J Clowers, Mi-Young Jeong, Yeyun Ouyang, Jordan A Berg, Jeremy P Gygi, Steven P Gygi, Dennis R Winge, Jared Rutter. Mol Cell 2018
23
Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly.
Alok Pandey, Donna M Gordon, Jayashree Pain, Timothy L Stemmler, Andrew Dancis, Debkumar Pain. J Biol Chem 2013
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Formation of [4Fe-4S] clusters in the mitochondrial iron-sulfur cluster assembly machinery.
Diego Brancaccio, Angelo Gallo, Maciej Mikolajczyk, Kairit Zovo, Peep Palumaa, Ettore Novellino, Mario Piccioli, Simone Ciofi-Baffoni, Lucia Banci. J Am Chem Soc 2014
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17
ISCA1 is essential for mitochondrial Fe4S4 biogenesis in vivo.
Lena Kristina Beilschmidt, Sandrine Ollagnier de Choudens, Marjorie Fournier, Ioannis Sanakis, Marc-André Hograindleur, Martin Clémancey, Geneviève Blondin, Stéphane Schmucker, Aurélie Eisenmann, Amélie Weiss,[...]. Nat Commun 2017
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20
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts.
Hong Ye, Suh Young Jeong, Manik C Ghosh, Gennadiy Kovtunovych, Laura Silvestri, Danilo Ortillo, Naoya Uchida, John Tisdale, Clara Camaschella, Tracey A Rouault. J Clin Invest 2010
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17
Mitochondrial [4Fe-4S] protein assembly involves reductive [2Fe-2S] cluster fusion on ISCA1-ISCA2 by electron flow from ferredoxin FDX2.
Benjamin Dennis Weiler, Marie-Christin Brück, Isabell Kothe, Eckhard Bill, Roland Lill, Ulrich Mühlenhoff. Proc Natl Acad Sci U S A 2020
Benjamin Dennis Weiler, Marie-Christin Brück, Isabell Kothe, Eckhard Bill, Roland Lill, Ulrich Mühlenhoff. Proc Natl Acad Sci U S A 2020
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Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly.
Florent Colin, Alain Martelli, Martin Clémancey, Jean-Marc Latour, Serge Gambarelli, Laura Zeppieri, Catherine Birck, Adeline Page, Hélène Puccio, Sandrine Ollagnier de Choudens. J Am Chem Soc 2013
Florent Colin, Alain Martelli, Martin Clémancey, Jean-Marc Latour, Serge Gambarelli, Laura Zeppieri, Catherine Birck, Adeline Page, Hélène Puccio, Sandrine Ollagnier de Choudens. J Am Chem Soc 2013
15
The in vivo mitochondrial two-step maturation of human frataxin.
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Stéphane Schmucker, Manuela Argentini, Nadège Carelle-Calmels, Alain Martelli, Hélène Puccio. Hum Mol Genet 2008
15
Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering.
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An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.
Jana Gerber, Ulrich Mühlenhoff, Roland Lill. EMBO Rep 2003
Jana Gerber, Ulrich Mühlenhoff, Roland Lill. EMBO Rep 2003
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Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis.
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Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin.
M Babcock, D de Silva, R Oaks, S Davis-Kaplan, S Jiralerspong, L Montermini, M Pandolfo, J Kaplan. Science 1997
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Exploring iron-binding to human frataxin and to selected Friedreich ataxia mutants by means of NMR and EPR spectroscopies.
Massimo Bellanda, Lorenzo Maso, Davide Doni, Marco Bortolus, Edith De Rosa, Federica Lunardi, Arianna Alfonsi, Martín Ezequiel Noguera, Maria Georgina Herrera, Javier Santos,[...]. Biochim Biophys Acta Proteins Proteom 2019
Massimo Bellanda, Lorenzo Maso, Davide Doni, Marco Bortolus, Edith De Rosa, Federica Lunardi, Arianna Alfonsi, Martín Ezequiel Noguera, Maria Georgina Herrera, Javier Santos,[...]. Biochim Biophys Acta Proteins Proteom 2019
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The mitochondrial Hsp70 chaperone Ssq1 facilitates Fe/S cluster transfer from Isu1 to Grx5 by complex formation.
Marta A Uzarska, Rafal Dutkiewicz, Sven-Andreas Freibert, Roland Lill, Ulrich Mühlenhoff. Mol Biol Cell 2013
Marta A Uzarska, Rafal Dutkiewicz, Sven-Andreas Freibert, Roland Lill, Ulrich Mühlenhoff. Mol Biol Cell 2013
15
Formation and properties of [4Fe-4S] clusters on the IscU scaffold protein.
Kala Chandramouli, Mihaela-Carmen Unciuleac, Sunil Naik, Dennis R Dean, Boi Hanh Huynh, Michael K Johnson. Biochemistry 2007
Kala Chandramouli, Mihaela-Carmen Unciuleac, Sunil Naik, Dennis R Dean, Boi Hanh Huynh, Michael K Johnson. Biochemistry 2007
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Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients.
Andrew Melber, Un Na, Ajay Vashisht, Benjamin D Weiler, Roland Lill, James A Wohlschlegel, Dennis R Winge. Elife 2016
Andrew Melber, Un Na, Ajay Vashisht, Benjamin D Weiler, Roland Lill, James A Wohlschlegel, Dennis R Winge. Elife 2016
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.