Francesca Alfei, Kristiyan Kanev, Maike Hofmann, Ming Wu, Hazem E Ghoneim, Patrick Roelli, Daniel T Utzschneider, Madlaina von Hoesslin, Jolie G Cullen, Yiping Fan, Vasyl Eisenberg, Dirk Wohlleber, Katja Steiger, Doron Merkler, Mauro Delorenzi, Percy A Knolle, Cyrille J Cohen, Robert Thimme, Benjamin Youngblood, Dietmar Zehn. Nature 2019
Times Cited: 302
Times Cited: 302
Times Cited
Times Co-cited
Similarity
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion.
Omar Khan, Josephine R Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P Patel, Michael T Werner, Alexander C Huang, Katherine A Alexander, Jennifer E Wu,[...]. Nature 2019
Omar Khan, Josephine R Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P Patel, Michael T Werner, Alexander C Huang, Katherine A Alexander, Jennifer E Wu,[...]. Nature 2019
80
TOX is a critical regulator of tumour-specific T cell differentiation.
Andrew C Scott, Friederike Dündar, Paul Zumbo, Smita S Chandran, Christopher A Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara,[...]. Nature 2019
Andrew C Scott, Friederike Dündar, Paul Zumbo, Smita S Chandran, Christopher A Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara,[...]. Nature 2019
76
TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.
Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H Wang, Isaac F López-Moyado, Romain O Georges, Wade Zhang, Atsushi Onodera,[...]. Proc Natl Acad Sci U S A 2019
Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H Wang, Isaac F López-Moyado, Romain O Georges, Wade Zhang, Atsushi Onodera,[...]. Proc Natl Acad Sci U S A 2019
45
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.
Chen Yao, Hong-Wei Sun, Neal E Lacey, Yun Ji, E Ashley Moseman, Han-Yu Shih, Elisabeth F Heuston, Martha Kirby, Stacie Anderson, Jun Cheng,[...]. Nat Immunol 2019
Chen Yao, Hong-Wei Sun, Neal E Lacey, Yun Ji, E Ashley Moseman, Han-Yu Shih, Elisabeth F Heuston, Martha Kirby, Stacie Anderson, Jun Cheng,[...]. Nat Immunol 2019
39
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Se Jin Im, Masao Hashimoto, Michael Y Gerner, Junghwa Lee, Haydn T Kissick, Matheus C Burger, Qiang Shan, J Scott Hale, Judong Lee, Tahseen H Nasti,[...]. Nature 2016
Se Jin Im, Masao Hashimoto, Michael Y Gerner, Junghwa Lee, Haydn T Kissick, Matheus C Burger, Qiang Shan, J Scott Hale, Judong Lee, Tahseen H Nasti,[...]. Nature 2016
38
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer.
Laura M McLane, Mohamed S Abdel-Hakeem, E John Wherry. Annu Rev Immunol 2019
Laura M McLane, Mohamed S Abdel-Hakeem, E John Wherry. Annu Rev Immunol 2019
37
T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections.
Daniel T Utzschneider, Mélanie Charmoy, Vijaykumar Chennupati, Laurène Pousse, Daniela Pais Ferreira, Sandra Calderon-Copete, Maxime Danilo, Francesca Alfei, Maike Hofmann, Dominik Wieland,[...]. Immunity 2016
Daniel T Utzschneider, Mélanie Charmoy, Vijaykumar Chennupati, Laurène Pousse, Daniela Pais Ferreira, Sandra Calderon-Copete, Maxime Danilo, Francesca Alfei, Maike Hofmann, Dominik Wieland,[...]. Immunity 2016
36
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Kristen E Pauken, Morgan A Sammons, Pamela M Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam M Drake, Zeyu Chen, Debattama R Sen, Makoto Kurachi,[...]. Science 2016
Kristen E Pauken, Morgan A Sammons, Pamela M Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam M Drake, Zeyu Chen, Debattama R Sen, Makoto Kurachi,[...]. Science 2016
32
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
Brian C Miller, Debattama R Sen, Rose Al Abosy, Kevin Bi, Yamini V Virkud, Martin W LaFleur, Kathleen B Yates, Ana Lako, Kristen Felt, Girish S Naik,[...]. Nat Immunol 2019
Brian C Miller, Debattama R Sen, Rose Al Abosy, Kevin Bi, Yamini V Virkud, Martin W LaFleur, Kathleen B Yates, Ana Lako, Kristen Felt, Girish S Naik,[...]. Nat Immunol 2019
28
The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Gustavo J Martinez, Renata M Pereira, Tarmo Äijö, Edward Y Kim, Francesco Marangoni, Matthew E Pipkin, Susan Togher, Vigo Heissmeyer, Yi Chen Zhang, Shane Crotty,[...]. Immunity 2015
Gustavo J Martinez, Renata M Pereira, Tarmo Äijö, Edward Y Kim, Francesco Marangoni, Matthew E Pipkin, Susan Togher, Vigo Heissmeyer, Yi Chen Zhang, Shane Crotty,[...]. Immunity 2015
28
The epigenetic landscape of T cell exhaustion.
Debattama R Sen, James Kaminski, R Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B Yates, Hsiao-Wei Tsao, Jernej Godec, Martin W LaFleur, Flavian D Brown,[...]. Science 2016
Debattama R Sen, James Kaminski, R Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B Yates, Hsiao-Wei Tsao, Jernej Godec, Martin W LaFleur, Flavian D Brown,[...]. Science 2016
28
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Imran Siddiqui, Karin Schaeuble, Vijaykumar Chennupati, Silvia A Fuertes Marraco, Sandra Calderon-Copete, Daniela Pais Ferreira, Santiago J Carmona, Leonardo Scarpellino, David Gfeller, Sylvain Pradervand,[...]. Immunity 2019
Imran Siddiqui, Karin Schaeuble, Vijaykumar Chennupati, Silvia A Fuertes Marraco, Sandra Calderon-Copete, Daniela Pais Ferreira, Santiago J Carmona, Leonardo Scarpellino, David Gfeller, Sylvain Pradervand,[...]. Immunity 2019
27
Chromatin states define tumour-specific T cell dysfunction and reprogramming.
Mary Philip, Lauren Fairchild, Liping Sun, Ellen L Horste, Steven Camara, Mojdeh Shakiba, Andrew C Scott, Agnes Viale, Peter Lauer, Taha Merghoub,[...]. Nature 2017
Mary Philip, Lauren Fairchild, Liping Sun, Ellen L Horste, Steven Camara, Mojdeh Shakiba, Andrew C Scott, Agnes Viale, Peter Lauer, Taha Merghoub,[...]. Nature 2017
27
Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
26
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Makoto Kurachi, Josephine R Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang,[...]. Immunity 2020
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Makoto Kurachi, Josephine R Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang,[...]. Immunity 2020
26
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C Huang, John Johnson, Ryan P Staupe, Bertram Bengsch, Caiyue Xu,[...]. Immunity 2019
Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C Huang, John Johnson, Ryan P Staupe, Bertram Bengsch, Caiyue Xu,[...]. Immunity 2019
24
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.
Michael A Paley, Daniela C Kroy, Pamela M Odorizzi, Jonathan B Johnnidis, Douglas V Dolfi, Burton E Barnett, Elizabeth K Bikoff, Elizabeth J Robertson, Georg M Lauer, Steven L Reiner,[...]. Science 2012
Michael A Paley, Daniela C Kroy, Pamela M Odorizzi, Jonathan B Johnnidis, Douglas V Dolfi, Burton E Barnett, Elizabeth K Bikoff, Elizabeth J Robertson, Georg M Lauer, Steven L Reiner,[...]. Science 2012
24
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Russell W Jenkins, David J Lieb, Jonathan H Chen, Dennie T Frederick, Michal Barzily-Rokni,[...]. Cell 2018
Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Russell W Jenkins, David J Lieb, Jonathan H Chen, Dennie T Frederick, Michal Barzily-Rokni,[...]. Cell 2018
21
Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
William H Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M Valanparambil, Peng Li, Jian-Xin Lin, Bogumila T Konieczny, Se Jin Im, Gordon J Freeman,[...]. Immunity 2019
William H Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M Valanparambil, Peng Li, Jian-Xin Lin, Bogumila T Konieczny, Se Jin Im, Gordon J Freeman,[...]. Immunity 2019
21
Molecular and cellular insights into T cell exhaustion.
E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
21
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.
Travis A Doering, Alison Crawford, Jill M Angelosanto, Michael A Paley, Carly G Ziegler, E John Wherry. Immunity 2012
Travis A Doering, Alison Crawford, Jill M Angelosanto, Michael A Paley, Carly G Ziegler, E John Wherry. Immunity 2012
20
Defining 'T cell exhaustion'.
Christian U Blank, W Nicholas Haining, Werner Held, Patrick G Hogan, Axel Kallies, Enrico Lugli, Rachel C Lynn, Mary Philip, Anjana Rao, Nicholas P Restifo,[...]. Nat Rev Immunol 2019
Christian U Blank, W Nicholas Haining, Werner Held, Patrick G Hogan, Axel Kallies, Enrico Lugli, Rachel C Lynn, Mary Philip, Anjana Rao, Nicholas P Restifo,[...]. Nat Rev Immunol 2019
19
The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.
Tuoqi Wu, Yun Ji, E Ashley Moseman, Haifeng C Xu, Monica Manglani, Martha Kirby, Stacie M Anderson, Robin Handon, Elizabeth Kenyon, Abdel Elkahloun,[...]. Sci Immunol 2016
Tuoqi Wu, Yun Ji, E Ashley Moseman, Haifeng C Xu, Monica Manglani, Martha Kirby, Stacie M Anderson, Robin Handon, Elizabeth Kenyon, Abdel Elkahloun,[...]. Sci Immunol 2016
19
NR4A transcription factors limit CAR T cell function in solid tumours.
Joyce Chen, Isaac F López-Moyado, Hyungseok Seo, Chan-Wang J Lio, Laura J Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P Scott-Browne, Anjana Rao. Nature 2019
Joyce Chen, Isaac F López-Moyado, Hyungseok Seo, Chan-Wang J Lio, Laura J Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P Scott-Browne, Anjana Rao. Nature 2019
19
Restoring function in exhausted CD8 T cells during chronic viral infection.
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
19
Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection.
Kevin Man, Sarah S Gabriel, Yang Liao, Renee Gloury, Simon Preston, Darren C Henstridge, Marc Pellegrini, Dietmar Zehn, Friederike Berberich-Siebelt, Mark A Febbraio,[...]. Immunity 2017
Kevin Man, Sarah S Gabriel, Yang Liao, Renee Gloury, Simon Preston, Darren C Henstridge, Marc Pellegrini, Dietmar Zehn, Friederike Berberich-Siebelt, Mark A Febbraio,[...]. Immunity 2017
18
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Andrea Schietinger, Mary Philip, Varintra E Krisnawan, Edison Y Chiu, Jeffrey J Delrow, Ryan S Basom, Peter Lauer, Dirk G Brockstedt, Sue E Knoblaugh, Günter J Hämmerling,[...]. Immunity 2016
Andrea Schietinger, Mary Philip, Varintra E Krisnawan, Edison Y Chiu, Jeffrey J Delrow, Ryan S Basom, Peter Lauer, Dirk G Brockstedt, Sue E Knoblaugh, Günter J Hämmerling,[...]. Immunity 2016
18
Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
Ran He, Shiyue Hou, Cheng Liu, Anli Zhang, Qiang Bai, Miao Han, Yu Yang, Gang Wei, Ting Shen, Xinxin Yang,[...]. Nature 2016
Ran He, Shiyue Hou, Cheng Liu, Anli Zhang, Qiang Bai, Miao Han, Yu Yang, Gang Wei, Ting Shen, Xinxin Yang,[...]. Nature 2016
17
Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1.
Xinyuan Zhou, Shuyang Yu, Dong-Mei Zhao, John T Harty, Vladimir P Badovinac, Hai-Hui Xue. Immunity 2010
Xinyuan Zhou, Shuyang Yu, Dong-Mei Zhao, John T Harty, Vladimir P Badovinac, Hai-Hui Xue. Immunity 2010
15
CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer.
Ryan Zander, David Schauder, Gang Xin, Christine Nguyen, Xiaopeng Wu, Allan Zajac, Weiguo Cui. Immunity 2019
Ryan Zander, David Schauder, Gang Xin, Christine Nguyen, Xiaopeng Wu, Allan Zajac, Weiguo Cui. Immunity 2019
15
TOX promotes the exhaustion of antitumor CD8+ T cells by preventing PD1 degradation in hepatocellular carcinoma.
Xiaochen Wang, Qifeng He, Haiyuan Shen, Anliang Xia, Wenfang Tian, Weiwei Yu, Beicheng Sun. J Hepatol 2019
Xiaochen Wang, Qifeng He, Haiyuan Shen, Anliang Xia, Wenfang Tian, Weiwei Yu, Beicheng Sun. J Hepatol 2019
14
De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
Hazem E Ghoneim, Yiping Fan, Ardiana Moustaki, Hossam A Abdelsamed, Pradyot Dash, Pranay Dogra, Robert Carter, Walid Awad, Geoff Neale, Paul G Thomas,[...]. Cell 2017
Hazem E Ghoneim, Yiping Fan, Ardiana Moustaki, Hossam A Abdelsamed, Pradyot Dash, Pranay Dogra, Robert Carter, Walid Awad, Geoff Neale, Paul G Thomas,[...]. Cell 2017
14
Transcriptional control of effector and memory CD8+ T cell differentiation.
Susan M Kaech, Weiguo Cui. Nat Rev Immunol 2012
Susan M Kaech, Weiguo Cui. Nat Rev Immunol 2012
14
Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells.
Sema Kurtulus, Asaf Madi, Giulia Escobar, Max Klapholz, Jackson Nyman, Elena Christian, Mathias Pawlak, Danielle Dionne, Junrong Xia, Orit Rozenblatt-Rosen,[...]. Immunity 2019
Sema Kurtulus, Asaf Madi, Giulia Escobar, Max Klapholz, Jackson Nyman, Elena Christian, Mathias Pawlak, Danielle Dionne, Junrong Xia, Orit Rozenblatt-Rosen,[...]. Immunity 2019
13
Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction.
Xindong Liu, Yun Wang, Huiping Lu, Jing Li, Xiaowei Yan, Minglu Xiao, Jing Hao, Andrei Alekseev, Hiep Khong, Tenghui Chen,[...]. Nature 2019
Xindong Liu, Yun Wang, Huiping Lu, Jing Li, Xiaowei Yan, Minglu Xiao, Jing Hao, Andrei Alekseev, Hiep Khong, Tenghui Chen,[...]. Nature 2019
13
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells.
Pamela M Odorizzi, Kristen E Pauken, Michael A Paley, Arlene Sharpe, E John Wherry. J Exp Med 2015
Pamela M Odorizzi, Kristen E Pauken, Michael A Paley, Arlene Sharpe, E John Wherry. J Exp Med 2015
13
Viral immune evasion due to persistence of activated T cells without effector function.
A J Zajac, J N Blattman, K Murali-Krishna, D J Sourdive, M Suresh, J D Altman, R Ahmed. J Exp Med 1998
A J Zajac, J N Blattman, K Murali-Krishna, D J Sourdive, M Suresh, J D Altman, R Ahmed. J Exp Med 1998
13
TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells.
Takuya Sekine, André Perez-Potti, Son Nguyen, Jean-Baptiste Gorin, Vincent H Wu, Emma Gostick, Sian Llewellyn-Lacey, Quirin Hammer, Sara Falck-Jones, Sindhu Vangeti,[...]. Sci Immunol 2020
Takuya Sekine, André Perez-Potti, Son Nguyen, Jean-Baptiste Gorin, Vincent H Wu, Emma Gostick, Sian Llewellyn-Lacey, Quirin Hammer, Sara Falck-Jones, Sindhu Vangeti,[...]. Sci Immunol 2020
24
Early precursor T cells establish and propagate T cell exhaustion in chronic infection.
Daniel T Utzschneider, Sarah S Gabriel, David Chisanga, Renee Gloury, Patrick M Gubser, Ajithkumar Vasanthakumar, Wei Shi, Axel Kallies. Nat Immunol 2020
Daniel T Utzschneider, Sarah S Gabriel, David Chisanga, Renee Gloury, Patrick M Gubser, Ajithkumar Vasanthakumar, Wei Shi, Axel Kallies. Nat Immunol 2020
22
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
12
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.
Caroline S Jansen, Nataliya Prokhnevska, Viraj A Master, Martin G Sanda, Jennifer W Carlisle, Mehmet Asim Bilen, Maria Cardenas, Scott Wilkinson, Ross Lake, Adam G Sowalsky,[...]. Nature 2019
Caroline S Jansen, Nataliya Prokhnevska, Viraj A Master, Martin G Sanda, Jennifer W Carlisle, Mehmet Asim Bilen, Maria Cardenas, Scott Wilkinson, Ross Lake, Adam G Sowalsky,[...]. Nature 2019
12
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.
Nikhil S Joshi, Weiguo Cui, Anmol Chandele, Heung Kyu Lee, David R Urso, James Hagman, Laurent Gapin, Susan M Kaech. Immunity 2007
Nikhil S Joshi, Weiguo Cui, Anmol Chandele, Heung Kyu Lee, David R Urso, James Hagman, Laurent Gapin, Susan M Kaech. Immunity 2007
12
Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade.
Rohit R Jadhav, Se Jin Im, Bin Hu, Masao Hashimoto, Peng Li, Jian-Xin Lin, Warren J Leonard, William J Greenleaf, Rafi Ahmed, Jorg J Goronzy. Proc Natl Acad Sci U S A 2019
Rohit R Jadhav, Se Jin Im, Bin Hu, Masao Hashimoto, Peng Li, Jian-Xin Lin, Warren J Leonard, William J Greenleaf, Rafi Ahmed, Jorg J Goronzy. Proc Natl Acad Sci U S A 2019
12
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.
Hanjie Li, Anne M van der Leun, Ido Yofe, Yaniv Lubling, Dikla Gelbard-Solodkin, Alexander C J van Akkooi, Marlous van den Braber, Elisa A Rozeman, John B A G Haanen, Christian U Blank,[...]. Cell 2019
Hanjie Li, Anne M van der Leun, Ido Yofe, Yaniv Lubling, Dikla Gelbard-Solodkin, Alexander C J van Akkooi, Marlous van den Braber, Elisa A Rozeman, John B A G Haanen, Christian U Blank,[...]. Cell 2019
11
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.
Shawn D Blackburn, Haina Shin, W Nicholas Haining, Tao Zou, Creg J Workman, Antonio Polley, Michael R Betts, Gordon J Freeman, Dario A A Vignali, E John Wherry. Nat Immunol 2009
Shawn D Blackburn, Haina Shin, W Nicholas Haining, Tao Zou, Creg J Workman, Antonio Polley, Michael R Betts, Gordon J Freeman, Dario A A Vignali, E John Wherry. Nat Immunol 2009
11
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.
Bertram Bengsch, Andy L Johnson, Makoto Kurachi, Pamela M Odorizzi, Kristen E Pauken, John Attanasio, Erietta Stelekati, Laura M McLane, Michael A Paley, Greg M Delgoffe,[...]. Immunity 2016
Bertram Bengsch, Andy L Johnson, Makoto Kurachi, Pamela M Odorizzi, Kristen E Pauken, John Attanasio, Erietta Stelekati, Laura M McLane, Michael A Paley, Greg M Delgoffe,[...]. Immunity 2016
11
Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.
Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu Setty, Sasikanth Manne, Shaun O'Brien, Pier Federico Gherardini, Ramin Sedaghat Herati, Alexander C Huang, Kyong-Mi Chang,[...]. Immunity 2018
Bertram Bengsch, Takuya Ohtani, Omar Khan, Manu Setty, Sasikanth Manne, Shaun O'Brien, Pier Federico Gherardini, Ramin Sedaghat Herati, Alexander C Huang, Kyong-Mi Chang,[...]. Immunity 2018
11
T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion.
Daniel T Utzschneider, Amandine Legat, Silvia A Fuertes Marraco, Lucie Carrié, Immanuel Luescher, Daniel E Speiser, Dietmar Zehn. Nat Immunol 2013
Daniel T Utzschneider, Amandine Legat, Silvia A Fuertes Marraco, Lucie Carrié, Immanuel Luescher, Daniel E Speiser, Dietmar Zehn. Nat Immunol 2013
11
CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.
Yew Ann Leong, Yaping Chen, Hong Sheng Ong, Di Wu, Kevin Man, Claire Deleage, Martina Minnich, Benjamin J Meckiff, Yunbo Wei, Zhaohua Hou,[...]. Nat Immunol 2016
Yew Ann Leong, Yaping Chen, Hong Sheng Ong, Di Wu, Kevin Man, Claire Deleage, Martina Minnich, Benjamin J Meckiff, Yunbo Wei, Zhaohua Hou,[...]. Nat Immunol 2016
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.