A citation-based method for searching scientific literature

Cheryl E G Leyns, Maud Gratuze, Sneha Narasimhan, Nimansha Jain, Lauren J Koscal, Hong Jiang, Melissa Manis, Marco Colonna, Virginia M Y Lee, Jason D Ulrich, David M Holtzman. Nat Neurosci 2019
Times Cited: 104







List of co-cited articles
1627 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
56

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
44

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
43

Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
40

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
868
38

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.
Cheryl E G Leyns, Jason D Ulrich, Mary B Finn, Floy R Stewart, Lauren J Koscal, Javier Remolina Serrano, Grace O Robinson, Elise Anderson, Marco Colonna, David M Holtzman. Proc Natl Acad Sci U S A 2017
212
36

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan,[...]. J Exp Med 2016
394
35

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski,[...]. Nat Neurosci 2019
222
34

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Shane M Bemiller, Tyler J McCray, Kevin Allan, Shane V Formica, Guixiang Xu, Gina Wilson, Olga N Kokiko-Cochran, Samuel D Crish, Cristian A Lasagna-Reeves, Richard M Ransohoff,[...]. Mol Neurodegener 2017
133
30

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Peng Yuan, Carlo Condello, C Dirk Keene, Yaming Wang, Thomas D Bird, Steven M Paul, Wenjie Luo, Marco Colonna, David Baddeley, Jaime Grutzendler. Neuron 2016
328
27

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Tyler K Ulland, Wilbur M Song, Stanley Ching-Cheng Huang, Jason D Ulrich, Alexey Sergushichev, Wandy L Beatty, Alexander A Loboda, Yingyue Zhou, Nigel J Cairns, Amal Kambal,[...]. Cell 2017
493
25

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation.
Zhuohao He, Jing L Guo, Jennifer D McBride, Sneha Narasimhan, Hyesung Kim, Lakshmi Changolkar, Bin Zhang, Ronald J Gathagan, Cuiyong Yue, Christopher Dengler,[...]. Nat Med 2018
287
25

Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Hirohide Asai, Seiko Ikezu, Satoshi Tsunoda, Maria Medalla, Jennifer Luebke, Tarik Haydar, Benjamin Wolozin, Oleg Butovsky, Sebastian Kügler, Tsuneya Ikezu. Nat Neurosci 2015
829
25

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan C Piña-Crespo, Muxian Zhang,[...]. Neuron 2018
289
24

NLRP3 inflammasome activation drives tau pathology.
Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera,[...]. Nature 2019
430
22


ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
541
21

Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration.
Maud Gratuze, Cheryl Eg Leyns, Andrew D Sauerbeck, Marie-Kim St-Pierre, Monica Xiong, Nayeon Kim, Javier Remolina Serrano, Marie-Ève Tremblay, Terrance T Kummer, Marco Colonna,[...]. J Clin Invest 2020
71
29

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
Taylor R Jay, Crystal M Miller, Paul J Cheng, Leah C Graham, Shane Bemiller, Margaret L Broihier, Guixiang Xu, Daniel Margevicius, J Colleen Karlo, Gregory L Sousa,[...]. J Exp Med 2015
427
20

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Elizabeth Spangenberg, Paul L Severson, Lindsay A Hohsfield, Joshua Crapser, Jiazhong Zhang, Elizabeth A Burton, Ying Zhang, Wayne Spevak, Jack Lin, Nicole Y Phan,[...]. Nat Commun 2019
265
20

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan,[...]. Nat Med 2020
295
20

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M Holtzman. J Exp Med 2019
136
20

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu,[...]. J Biol Chem 2015
276
19

New insights into the role of TREM2 in Alzheimer's disease.
Maud Gratuze, Cheryl E G Leyns, David M Holtzman. Mol Neurodegener 2018
190
19

TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Ana Griciuc, Shaun Patel, Anthony N Federico, Se Hoon Choi, Brendan J Innes, Mary K Oram, Gea Cereghetti, Danielle McGinty, Anthony Anselmo, Ruslan I Sadreyev,[...]. Neuron 2019
134
19


Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
Faten A Sayed, Maria Telpoukhovskaia, Lay Kodama, Yaqiao Li, Yungui Zhou, David Le, Axel Hauduc, Connor Ludwig, Fuying Gao, Claire Clelland,[...]. Proc Natl Acad Sci U S A 2018
69
26

Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
18

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model.
Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C Saido, Jun Maeda, Tetsuya Suhara, John Q Trojanowski, Virginia M-Y Lee. Neuron 2007
18

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
Michael Ewers, Nicolai Franzmeier, Marc Suárez-Calvet, Estrella Morenas-Rodriguez, Miguel Angel Araque Caballero, Gernot Kleinberger, Laura Piccio, Carlos Cruchaga, Yuetiva Deming, Martin Dichgans,[...]. Sci Transl Med 2019
118
18

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
Taylor R Jay, Anna M Hirsch, Margaret L Broihier, Crystal M Miller, Lee E Neilson, Richard M Ransohoff, Bruce T Lamb, Gary E Landreth. J Neurosci 2017
236
17

Microglia in Alzheimer's disease.
David V Hansen, Jesse E Hanson, Morgan Sheng. J Cell Biol 2018
657
17

The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
17

Single-cell transcriptomic analysis of Alzheimer's disease.
Hansruedi Mathys, Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z Young, Madhvi Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang,[...]. Nature 2019
742
17

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
995
17

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti-Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner,[...]. EMBO Mol Med 2020
82
20

TREM2 - a key player in microglial biology and Alzheimer disease.
Tyler K Ulland, Marco Colonna. Nat Rev Neurol 2018
231
16

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.
Carlo Condello, Peng Yuan, Aaron Schain, Jaime Grutzendler. Nat Commun 2015
296
16

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.
Holly Oakley, Sarah L Cole, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John Disterhoft, Linda Van Eldik,[...]. J Neurosci 2006
16

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
Michael T Heneka, Markus P Kummer, Andrea Stutz, Andrea Delekate, Stephanie Schwartz, Ana Vieira-Saecker, Angelika Griep, Daisy Axt, Anita Remus, Te-Chen Tzeng,[...]. Nature 2013
16

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Alicia A Nugent, Karin Lin, Bettina van Lengerich, Steve Lianoglou, Laralynne Przybyla, Sonnet S Davis, Ceyda Llapashtica, Junhua Wang, Do Jin Kim, Dan Xia,[...]. Neuron 2020
178
16

Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
16

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain.
Nicole Maphis, Guixiang Xu, Olga N Kokiko-Cochran, Shanya Jiang, Astrid Cardona, Richard M Ransohoff, Bruce T Lamb, Kiran Bhaskar. Brain 2015
285
16

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
C Y Daniel Lee, Anthony Daggett, Xiaofeng Gu, Lu-Lin Jiang, Peter Langfelder, Xiaoguang Li, Nan Wang, Yingjun Zhao, Chang Sin Park, Yonatan Cooper,[...]. Neuron 2018
169
15

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit. Cell 2018
429
15

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
15

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Renzo Mancuso, Gemma Fryatt, Madeleine Cleal, Juliane Obst, Elena Pipi, Jimena Monzón-Sandoval, Elena Ribe, Laura Winchester, Caleb Webber, Alejo Nevado,[...]. Brain 2019
88
17

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease.
Sarah C Hopp, Yang Lin, Derek Oakley, Allyson D Roe, Sarah L DeVos, David Hanlon, Bradley T Hyman. J Neuroinflammation 2018
113
15

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, Eva Czirr, Ebba Lohmann, Elise Cuyvers, Hanne Struyfs, Nadine Pettkus, Andrea Wenninger-Weinzierl, Fargol Mazaheri,[...]. Sci Transl Med 2014
452
14

Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.