A citation-based method for searching scientific literature

Jade D Bailey, Marina Diotallevi, Thomas Nicol, Eileen McNeill, Andrew Shaw, Surawee Chuaiphichai, Ashley Hale, Anna Starr, Manasi Nandi, Elena Stylianou, Helen McShane, Simon Davis, Roman Fischer, Benedikt M Kessler, James McCullagh, Keith M Channon, Mark J Crabtree. Cell Rep 2019
Times Cited: 77







List of co-cited articles
793 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
46

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
551
42

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M Stewart, Juliet Ashall, Bart Everts,[...]. Immunity 2015
889
41

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
839
38

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
586
32

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell,[...]. Proc Natl Acad Sci U S A 2013
487
31

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Pu-Ste Liu, Haiping Wang, Xiaoyun Li, Tung Chao, Tony Teav, Stefan Christen, Giusy Di Conza, Wan-Chen Cheng, Chih-Hung Chou, Magdalena Vavakova,[...]. Nat Immunol 2017
374
25

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.
Erika M Palmieri, Marieli Gonzalez-Cotto, Walter A Baseler, Luke C Davies, Bart Ghesquière, Nunziata Maio, Christopher M Rice, Tracey A Rouault, Teresa Cassel, Richard M Higashi,[...]. Nat Commun 2020
97
25

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Jan Van den Bossche, Jeroen Baardman, Natasja A Otto, Saskia van der Velden, Annette E Neele, Susan M van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C S Boshuizen, Mohamed Ahmed,[...]. Cell Rep 2016
343
24

Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston,[...]. Cell Metab 2015
544
22

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Stanley Ching-Cheng Huang, Bart Everts, Yulia Ivanova, David O'Sullivan, Marcia Nascimento, Amber M Smith, Wandy Beatty, Latisha Love-Gregory, Wing Y Lam, Christina M O'Neill,[...]. Nat Immunol 2014
602
20

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.
Bart Everts, Eyal Amiel, Gerritje J W van der Windt, Tori C Freitas, Robert Chott, Kevin E Yarasheski, Erika L Pearce, Edward J Pearce. Blood 2012
348
20

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
Thekla Cordes, Martina Wallace, Alessandro Michelucci, Ajit S Divakaruni, Sean C Sapcariu, Carole Sousa, Haruhiko Koseki, Pedro Cabrales, Anne N Murphy, Karsten Hiller,[...]. J Biol Chem 2016
222
20

Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang,[...]. Nature 2018
257
19

Itaconate: the poster child of metabolic reprogramming in macrophage function.
Luke A J O'Neill, Maxim N Artyomov. Nat Rev Immunol 2019
152
16

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
Divya Vats, Lata Mukundan, Justin I Odegaard, Lina Zhang, Kristi L Smith, Christine R Morel, Roger A Wagner, David R Greaves, Peter J Murray, Ajay Chawla. Cell Metab 2006
849
16

Immunometabolism governs dendritic cell and macrophage function.
Luke A J O'Neill, Edward J Pearce. J Exp Med 2016
779
15

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
A Phillip West, Igor E Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C Walsh, Yongwon Choi, Gerald S Shadel, Sankar Ghosh. Nature 2011
925
15

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage.
Alanna M Cameron, Angela Castoldi, David E Sanin, Lea J Flachsmann, Cameron S Field, Daniel J Puleston, Ryan L Kyle, Annette E Patterson, Fabian Hässler, Joerg M Buescher,[...]. Nat Immunol 2019
84
15

The mitochondrial citrate carrier: a new player in inflammation.
Vittoria Infantino, Paolo Convertini, Liana Cucci, Maria Antonietta Panaro, Maria Antonietta Di Noia, Rosa Calvello, Ferdinando Palmieri, Vito Iacobazzi. Biochem J 2011
230
15

A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
15

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
448
15

Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew S J Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen,[...]. Immunity 2019
103
15

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J W Arts, Boris Novakovic, Rob Ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih-Chin Cheng, Shuang-Yin Wang,[...]. Cell Metab 2016
384
14

Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation.
Gretchen L Seim, Emily C Britt, Steven V John, Franklin J Yeo, Aaron R Johnson, Richard S Eisenstein, David J Pagliarini, Jing Fan. Nat Metab 2019
38
28

Macrophage Immunometabolism: Where Are We (Going)?
Jan Van den Bossche, Luke A O'Neill, Deepthi Menon. Trends Immunol 2017
414
12

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
12

Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation.
Feilong Wang, Song Zhang, Ivan Vuckovic, Ryounghoon Jeon, Amir Lerman, Clifford D Folmes, Petras P Dzeja, Joerg Herrmann. Cell Metab 2018
118
12

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression.
Johannes Meiser, Lisa Krämer, Sean C Sapcariu, Nadia Battello, Jenny Ghelfi, Aymeric Fouquier D'Herouel, Alexander Skupin, Karsten Hiller. J Biol Chem 2016
120
12

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Bart Everts, Eyal Amiel, Stanley Ching-Cheng Huang, Amber M Smith, Chih-Hao Chang, Wing Y Lam, Veronika Redmann, Tori C Freitas, Julianna Blagih, Gerritje J W van der Windt,[...]. Nat Immunol 2014
596
12

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.
Shih-Chin Cheng, Jessica Quintin, Robert A Cramer, Kelly M Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J Giamarellos-Bourboulis, Joost H A Martens, Nagesha Appukudige Rao, Ali Aghajanirefah,[...]. Science 2014
975
12

Itaconic acid is a mammalian metabolite induced during macrophage activation.
Cheryl L Strelko, Wenyun Lu, Fay J Dufort, Thomas N Seyfried, Thomas C Chiles, Joshua D Rabinowitz, Mary F Roberts. J Am Chem Soc 2011
167
12


Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.
Johan Garaude, Rebeca Acín-Pérez, Sarai Martínez-Cano, Michel Enamorado, Matteo Ugolini, Estanislao Nistal-Villán, Sandra Hervás-Stubbs, Pablo Pelegrín, Leif E Sander, José A Enríquez,[...]. Nat Immunol 2016
164
12

S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate.
Wei Qin, Ke Qin, Yanling Zhang, Wentong Jia, Ying Chen, Bo Cheng, Linghang Peng, Nan Chen, Yuan Liu, Wen Zhou,[...]. Nat Chem Biol 2019
75
13

Krebs Cycle Reborn in Macrophage Immunometabolism.
Dylan G Ryan, Luke A J O'Neill. Annu Rev Immunol 2020
82
12

4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects.
Shan-Ting Liao, Chao Han, Ding-Qiao Xu, Xiao-Wei Fu, Jun-Song Wang, Ling-Yi Kong. Nat Commun 2019
85
12

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes.
Ekta Lachmandas, Lily Boutens, Jacqueline M Ratter, Anneke Hijmans, Guido J Hooiveld, Leo A B Joosten, Richard J Rodenburg, Jack A M Fransen, Riekelt H Houtkooper, Reinout van Crevel,[...]. Nat Microbiol 2016
157
12

The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism.
Arvand Haschemi, Paul Kosma, Lars Gille, Charles R Evans, Charles F Burant, Philipp Starkl, Bernhard Knapp, Robert Haas, Johannes A Schmid, Christoph Jandl,[...]. Cell Metab 2012
344
11


Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation.
Anthony J Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W Snyder, Andrew J Worth, Shankar S Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul,[...]. Elife 2016
234
11

ATP-citrate lyase is essential for macrophage inflammatory response.
Vittoria Infantino, Vito Iacobazzi, Ferdinando Palmieri, Alessio Menga. Biochem Biophys Res Commun 2013
145
11

Malonylation of GAPDH is an inflammatory signal in macrophages.
Silvia Galván-Peña, Richard G Carroll, Carla Newman, Elizabeth C Hinchy, Eva Palsson-McDermott, Elektra K Robinson, Sergio Covarrubias, Alan Nadin, Andrew M James, Moritz Haneklaus,[...]. Nat Commun 2019
60
15

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Stanley Ching-Cheng Huang, Amber M Smith, Bart Everts, Marco Colonna, Erika L Pearce, Joel D Schilling, Edward J Pearce. Immunity 2016
290
11

Macrophage activation and polarization: nomenclature and experimental guidelines.
Peter J Murray, Judith E Allen, Subhra K Biswas, Edward A Fisher, Derek W Gilroy, Sergij Goerdt, Siamon Gordon, John A Hamilton, Lionel B Ivashkiv, Toby Lawrence,[...]. Immunity 2014
11

Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages.
Amanda Swain, Monika Bambouskova, Hyeryun Kim, Prabhakar Sairam Andhey, Dustin Duncan, Karine Auclair, Victor Chubukov, Donald M Simons, Thomas P Roddy, Kelly M Stewart,[...]. Nat Metab 2020
60
15

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.
Justin I Odegaard, Roberto R Ricardo-Gonzalez, Matthew H Goforth, Christine R Morel, Vidya Subramanian, Lata Mukundan, Alex Red Eagle, Divya Vats, Frank Brombacher, Anthony W Ferrante,[...]. Nature 2007
10

HIF-1alpha is essential for myeloid cell-mediated inflammation.
Thorsten Cramer, Yuji Yamanishi, Björn E Clausen, Irmgard Förster, Rafal Pawlinski, Nigel Mackman, Volker H Haase, Rudolf Jaenisch, Maripat Corr, Victor Nizet,[...]. Cell 2003
10

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.
Amanda Littlewood-Evans, Sophie Sarret, Verena Apfel, Perrine Loesle, Janet Dawson, Juan Zhang, Alban Muller, Bruno Tigani, Rainer Kneuer, Saijel Patel,[...]. J Exp Med 2016
206
10



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.