C Frank Bennett, Adrian R Krainer, Don W Cleveland. Annu Rev Neurosci 2019
Times Cited: 90
Times Cited: 90
Times Cited
Times Co-cited
Similarity
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
25
Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.
Richard S Finkel, Eugenio Mercuri, Basil T Darras, Anne M Connolly, Nancy L Kuntz, Janbernd Kirschner, Claudia A Chiriboga, Kayoko Saito, Laurent Servais, Eduardo Tizzano,[...]. N Engl J Med 2017
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RNA-Targeted Therapeutics.
Stanley T Crooke, Joseph L Witztum, C Frank Bennett, Brenda F Baker. Cell Metab 2018
Stanley T Crooke, Joseph L Witztum, C Frank Bennett, Brenda F Baker. Cell Metab 2018
14
Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Holly B Kordasiewicz, Lisa M Stanek, Edward V Wancewicz, Curt Mazur, Melissa M McAlonis, Kimberly A Pytel, Jonathan W Artates, Andreas Weiss, Seng H Cheng, Lamya S Shihabuddin,[...]. Neuron 2012
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12
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study.
Richard S Finkel, Claudia A Chiriboga, Jiri Vajsar, John W Day, Jacqueline Montes, Darryl C De Vivo, Mason Yamashita, Frank Rigo, Gene Hung, Eugene Schneider,[...]. Lancet 2016
Richard S Finkel, Claudia A Chiriboga, Jiri Vajsar, John W Day, Jacqueline Montes, Darryl C De Vivo, Mason Yamashita, Frank Rigo, Gene Hung, Eugene Schneider,[...]. Lancet 2016
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An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study.
Timothy M Miller, Alan Pestronk, William David, Jeffrey Rothstein, Ericka Simpson, Stanley H Appel, Patricia L Andres, Katy Mahoney, Peggy Allred, Katie Alexander,[...]. Lancet Neurol 2013
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11
Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy.
Eugenio Mercuri, Basil T Darras, Claudia A Chiriboga, John W Day, Craig Campbell, Anne M Connolly, Susan T Iannaccone, Janbernd Kirschner, Nancy L Kuntz, Kayoko Saito,[...]. N Engl J Med 2018
Eugenio Mercuri, Basil T Darras, Claudia A Chiriboga, John W Day, Craig Campbell, Anne M Connolly, Susan T Iannaccone, Janbernd Kirschner, Nancy L Kuntz, Kayoko Saito,[...]. N Engl J Med 2018
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
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Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.
P C Zamecnik, M L Stephenson. Proc Natl Acad Sci U S A 1978
P C Zamecnik, M L Stephenson. Proc Natl Acad Sci U S A 1978
10
Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides.
Richard S Geary, Daniel Norris, Rosie Yu, C Frank Bennett. Adv Drug Deliv Rev 2015
Richard S Geary, Daniel Norris, Rosie Yu, C Frank Bennett. Adv Drug Deliv Rev 2015
10
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
8
8
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.
Wen Shen, Cheryl L De Hoyos, Michael T Migawa, Timothy A Vickers, Hong Sun, Audrey Low, Thomas A Bell, Meghdad Rahdar, Swagatam Mukhopadhyay, Christopher E Hart,[...]. Nat Biotechnol 2019
Wen Shen, Cheryl L De Hoyos, Michael T Migawa, Timothy A Vickers, Hong Sun, Audrey Low, Thomas A Bell, Meghdad Rahdar, Swagatam Mukhopadhyay, Christopher E Hart,[...]. Nat Biotechnol 2019
8
Identification and characterization of a spinal muscular atrophy-determining gene.
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8
Results from a phase 1 study of nusinersen (ISIS-SMN(Rx)) in children with spinal muscular atrophy.
Claudia A Chiriboga, Kathryn J Swoboda, Basil T Darras, Susan T Iannaccone, Jacqueline Montes, Darryl C De Vivo, Daniel A Norris, C Frank Bennett, Kathie M Bishop. Neurology 2016
Claudia A Chiriboga, Kathryn J Swoboda, Basil T Darras, Susan T Iannaccone, Jacqueline Montes, Darryl C De Vivo, Daniel A Norris, C Frank Bennett, Kathie M Bishop. Neurology 2016
8
Antisense oligonucleotide therapy for neurodegenerative disease.
Richard A Smith, Timothy M Miller, Koji Yamanaka, Brett P Monia, Thomas P Condon, Gene Hung, Christian S Lobsiger, Chris M Ward, Melissa McAlonis-Downes, Hongbing Wei,[...]. J Clin Invest 2006
Richard A Smith, Timothy M Miller, Koji Yamanaka, Brett P Monia, Thomas P Condon, Gene Hung, Christian S Lobsiger, Chris M Ward, Melissa McAlonis-Downes, Hongbing Wei,[...]. J Clin Invest 2006
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Phosphorothioate modified oligonucleotide-protein interactions.
Stanley T Crooke, Timothy A Vickers, Xue-Hai Liang. Nucleic Acids Res 2020
Stanley T Crooke, Timothy A Vickers, Xue-Hai Liang. Nucleic Acids Res 2020
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Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
Jie Jiang, Qiang Zhu, Tania F Gendron, Shahram Saberi, Melissa McAlonis-Downes, Amanda Seelman, Jennifer E Stauffer, Paymaan Jafar-Nejad, Kevin Drenner, Derek Schulte,[...]. Neuron 2016
Jie Jiang, Qiang Zhu, Tania F Gendron, Shahram Saberi, Melissa McAlonis-Downes, Amanda Seelman, Jennifer E Stauffer, Paymaan Jafar-Nejad, Kevin Drenner, Derek Schulte,[...]. Neuron 2016
7
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.
Lindsay A Becker, Brenda Huang, Gregor Bieri, Rosanna Ma, David A Knowles, Paymaan Jafar-Nejad, James Messing, Hong Joo Kim, Armand Soriano, Georg Auburger,[...]. Nature 2017
Lindsay A Becker, Brenda Huang, Gregor Bieri, Rosanna Ma, David A Knowles, Paymaan Jafar-Nejad, James Messing, Hong Joo Kim, Armand Soriano, Georg Auburger,[...]. Nature 2017
7
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
Tao Zu, Yuanjing Liu, Monica Bañez-Coronel, Tammy Reid, Olga Pletnikova, Jada Lewis, Timothy M Miller, Matthew B Harms, Annet E Falchook, S H Subramony,[...]. Proc Natl Acad Sci U S A 2013
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7
Antisense oligonucleotide therapy for spinocerebellar ataxia type 2.
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
7
Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study.
Sebahattin Cirak, Virginia Arechavala-Gomeza, Michela Guglieri, Lucy Feng, Silvia Torelli, Karen Anthony, Stephen Abbs, Maria Elena Garralda, John Bourke, Dominic J Wells,[...]. Lancet 2011
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7
Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy.
Diane E Frank, Frederick J Schnell, Cody Akana, Saleh H El-Husayni, Cody A Desjardins, Jennifer Morgan, Jay S Charleston, Valentina Sardone, Joana Domingos, George Dickson,[...]. Neurology 2020
Diane E Frank, Frederick J Schnell, Cody Akana, Saleh H El-Husayni, Cody A Desjardins, Jennifer Morgan, Jay S Charleston, Valentina Sardone, Joana Domingos, George Dickson,[...]. Neurology 2020
7
RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.
C Frank Bennett, Eric E Swayze. Annu Rev Pharmacol Toxicol 2010
C Frank Bennett, Eric E Swayze. Annu Rev Pharmacol Toxicol 2010
7
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
Timothy Miller, Merit Cudkowicz, Pamela J Shaw, Peter M Andersen, Nazem Atassi, Robert C Bucelli, Angela Genge, Jonathan Glass, Shafeeq Ladha, Albert L Ludolph,[...]. N Engl J Med 2020
Timothy Miller, Merit Cudkowicz, Pamela J Shaw, Peter M Andersen, Nazem Atassi, Robert C Bucelli, Angela Genge, Jonathan Glass, Shafeeq Ladha, Albert L Ludolph,[...]. N Engl J Med 2020
7
Non-ATG-initiated translation directed by microsatellite expansions.
Tao Zu, Brian Gibbens, Noelle S Doty, Mário Gomes-Pereira, Aline Huguet, Matthew D Stone, Jamie Margolis, Mark Peterson, Todd W Markowski, Melissa A C Ingram,[...]. Proc Natl Acad Sci U S A 2011
Tao Zu, Brian Gibbens, Noelle S Doty, Mário Gomes-Pereira, Aline Huguet, Matthew D Stone, Jamie Margolis, Mark Peterson, Todd W Markowski, Melissa A C Ingram,[...]. Proc Natl Acad Sci U S A 2011
6
Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron.
Nirmal K Singh, Natalia N Singh, Elliot J Androphy, Ravindra N Singh. Mol Cell Biol 2006
Nirmal K Singh, Natalia N Singh, Elliot J Androphy, Ravindra N Singh. Mol Cell Biol 2006
6
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models.
Alex McCampbell, Tracy Cole, Amy J Wegener, Giulio S Tomassy, Amy Setnicka, Brandon J Farley, Kathleen M Schoch, Mariah L Hoye, Mark Shabsovich, Linhong Sun,[...]. J Clin Invest 2018
Alex McCampbell, Tracy Cole, Amy J Wegener, Giulio S Tomassy, Amy Setnicka, Brandon J Farley, Kathleen M Schoch, Mariah L Hoye, Mark Shabsovich, Linhong Sun,[...]. J Clin Invest 2018
6
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease.
Jinkuk Kim, Chunguang Hu, Christelle Moufawad El Achkar, Lauren E Black, Julie Douville, Austin Larson, Mary K Pendergast, Sara F Goldkind, Eunjung A Lee, Ashley Kuniholm,[...]. N Engl J Med 2019
Jinkuk Kim, Chunguang Hu, Christelle Moufawad El Achkar, Lauren E Black, Julie Douville, Austin Larson, Mary K Pendergast, Sara F Goldkind, Eunjung A Lee, Ashley Kuniholm,[...]. N Engl J Med 2019
6
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
6
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice.
Haibo Zhou, Jinlin Su, Xinde Hu, Changyang Zhou, He Li, Zhaorong Chen, Qingquan Xiao, Bo Wang, Wenyan Wu, Yidi Sun,[...]. Cell 2020
Haibo Zhou, Jinlin Su, Xinde Hu, Changyang Zhou, He Li, Zhaorong Chen, Qingquan Xiao, Bo Wang, Wenyan Wu, Yidi Sun,[...]. Cell 2020
6
The current state and future directions of RNAi-based therapeutics.
Ryan L Setten, John J Rossi, Si-Ping Han. Nat Rev Drug Discov 2019
Ryan L Setten, John J Rossi, Si-Ping Han. Nat Rev Drug Discov 2019
6
Cellular uptake and trafficking of antisense oligonucleotides.
Stanley T Crooke, Shiyu Wang, Timothy A Vickers, Wen Shen, Xue-Hai Liang. Nat Biotechnol 2017
Stanley T Crooke, Shiyu Wang, Timothy A Vickers, Wen Shen, Xue-Hai Liang. Nat Biotechnol 2017
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Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages.
Xue-hai Liang, Hong Sun, Wen Shen, Stanley T Crooke. Nucleic Acids Res 2015
Xue-hai Liang, Hong Sun, Wen Shen, Stanley T Crooke. Nucleic Acids Res 2015
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Advances in oligonucleotide drug delivery.
Thomas C Roberts, Robert Langer, Matthew J A Wood. Nat Rev Drug Discov 2020
Thomas C Roberts, Robert Langer, Matthew J A Wood. Nat Rev Drug Discov 2020
6
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.
Xinmei Wen, Wenzhi Tan, Thomas Westergard, Karthik Krishnamurthy, Shashirekha S Markandaiah, Yingxiao Shi, Shaoyu Lin, Neil A Shneider, John Monaghan, Udai B Pandey,[...]. Neuron 2014
Xinmei Wen, Wenzhi Tan, Thomas Westergard, Karthik Krishnamurthy, Shashirekha S Markandaiah, Yingxiao Shi, Shaoyu Lin, Neil A Shneider, John Monaghan, Udai B Pandey,[...]. Neuron 2014
5
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Thomas Caulfield, Lillian Daughrity, Judith H Dunmore, Monica Castanedes-Casey, Jeannie Chew,[...]. Acta Neuropathol 2013
Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Thomas Caulfield, Lillian Daughrity, Judith H Dunmore, Monica Castanedes-Casey, Jeannie Chew,[...]. Acta Neuropathol 2013
5
5
Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.
Yimin Hua, Timothy A Vickers, Brenda F Baker, C Frank Bennett, Adrian R Krainer. PLoS Biol 2007
Yimin Hua, Timothy A Vickers, Brenda F Baker, C Frank Bennett, Adrian R Krainer. PLoS Biol 2007
5
C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
Aaron R Haeusler, Christopher J Donnelly, Goran Periz, Eric A J Simko, Patrick G Shaw, Min-Sik Kim, Nicholas J Maragakis, Juan C Troncoso, Akhilesh Pandey, Rita Sattler,[...]. Nature 2014
Aaron R Haeusler, Christopher J Donnelly, Goran Periz, Eric A J Simko, Patrick G Shaw, Min-Sik Kim, Nicholas J Maragakis, Juan C Troncoso, Akhilesh Pandey, Rita Sattler,[...]. Nature 2014
5
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Sarah Mizielinska, Sebastian Grönke, Teresa Niccoli, Charlotte E Ridler, Emma L Clayton, Anny Devoy, Thomas Moens, Frances E Norona, Ione O C Woollacott, Julian Pietrzyk,[...]. Science 2014
Sarah Mizielinska, Sebastian Grönke, Teresa Niccoli, Charlotte E Ridler, Emma L Clayton, Anny Devoy, Thomas Moens, Frances E Norona, Ione O C Woollacott, Julian Pietrzyk,[...]. Science 2014
5
Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
Lodewijk J A Toonen, Frank Rigo, Haico van Attikum, Willeke M C van Roon-Mom. Mol Ther Nucleic Acids 2017
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8
Spinocerebellar ataxia.
Thomas Klockgether, Caterina Mariotti, Henry L Paulson. Nat Rev Dis Primers 2019
Thomas Klockgether, Caterina Mariotti, Henry L Paulson. Nat Rev Dis Primers 2019
5
Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.
Hayley S McLoughlin, Lauren R Moore, Ravi Chopra, Robert Komlo, Megan McKenzie, Kate G Blumenstein, Hien Zhao, Holly B Kordasiewicz, Vikram G Shakkottai, Henry L Paulson. Ann Neurol 2018
Hayley S McLoughlin, Lauren R Moore, Ravi Chopra, Robert Komlo, Megan McKenzie, Kate G Blumenstein, Hien Zhao, Holly B Kordasiewicz, Vikram G Shakkottai, Henry L Paulson. Ann Neurol 2018
6
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals.
Eric E Swayze, Andrew M Siwkowski, Edward V Wancewicz, Michael T Migawa, Tadeusz K Wyrzykiewicz, Gene Hung, Brett P Monia, C Frank Bennett. Nucleic Acids Res 2007
Eric E Swayze, Andrew M Siwkowski, Edward V Wancewicz, Michael T Migawa, Tadeusz K Wyrzykiewicz, Gene Hung, Brett P Monia, C Frank Bennett. Nucleic Acids Res 2007
5
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease.
Amber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, Niels H Skotte, Matthew P Parsons, Erika B Villanueva, Nicholas S Caron, Michael E Østergaard, Lisa M Anderson, Yuanyun Xie,[...]. Sci Transl Med 2018
Amber L Southwell, Holly B Kordasiewicz, Douglas Langbehn, Niels H Skotte, Matthew P Parsons, Erika B Villanueva, Nicholas S Caron, Michael E Østergaard, Lisa M Anderson, Yuanyun Xie,[...]. Sci Transl Med 2018
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A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy.
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
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Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells.
Yuanchao Xue, Hao Qian, Jing Hu, Bing Zhou, Yu Zhou, Xihao Hu, Aziz Karakhanyan, Zhiping Pang, Xiang-Dong Fu. Nat Neurosci 2016
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8
Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy.
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5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.