A citation-based method for searching scientific literature

Jark Böttcher, David Dilworth, Ulrich Reiser, Ralph A Neumüller, Michael Schleicher, Mark Petronczki, Markus Zeeb, Nikolai Mischerikow, Abdellah Allali-Hassani, Magdalena M Szewczyk, Fengling Li, Steven Kennedy, Masoud Vedadi, Dalia Barsyte-Lovejoy, Peter J Brown, Kilian V M Huber, Catherine M Rogers, Carrow I Wells, Oleg Fedorov, Klaus Rumpel, Andreas Zoephel, Moriz Mayer, Tobias Wunberg, Dietrich Böse, Stephan Zahn, Heribert Arnhof, Helmut Berger, Christoph Reiser, Alexandra Hörmann, Teresa Krammer, Maja Corcokovic, Bernadette Sharps, Sandra Winkler, Daniela Häring, Xiao-Ling Cockcroft, Julian E Fuchs, Barbara Müllauer, Alexander Weiss-Puxbaum, Thomas Gerstberger, Guido Boehmelt, Christopher R Vakoc, Cheryl H Arrowsmith, Mark Pearson, Darryl B McConnell. Nat Chem Biol 2019
Times Cited: 28







List of co-cited articles
443 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Covalent inhibition of NSD1 histone methyltransferase.
Huang Huang, Christina A Howard, Sergei Zari, Hyo Je Cho, Shirish Shukla, Hao Li, Juliano Ndoj, Paula González-Alonso, Caroline Nikolaidis, Joshua Abbott,[...]. Nat Chem Biol 2020
28
42

The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer.
Richard L Bennett, Alok Swaroop, Catalina Troche, Jonathan D Licht. Cold Spring Harb Perspect Med 2017
78
32


Structure and function of the nucleosome-binding PWWP domain.
Su Qin, Jinrong Min. Trends Biochem Sci 2014
103
25

The NSD family of protein methyltransferases in human cancer.
Theodore Vougiouklakis, Ryuji Hamamoto, Yusuke Nakamura, Vassiliki Saloura. Epigenomics 2015
57
25

Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Wanqiu Li, Wei Tian, Gang Yuan, Pujuan Deng, Deepanwita Sengupta, Zhongjun Cheng, Yinghua Cao, Jiahao Ren, Yan Qin, Yuqiao Zhou,[...]. Nature 2021
36
25

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Man Zhang, Jeff Zhang, Zhengtian Yu, Ling Li,[...]. Nat Chem Biol 2017
177
21

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.
Yupeng He, Sujatha Selvaraju, Michael L Curtin, Clarissa G Jakob, Haizhong Zhu, Kenneth M Comess, Bailin Shaw, Juliana The, Evelyne Lima-Fernandes, Magdalena M Szewczyk,[...]. Nat Chem Biol 2017
128
21

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).
Roberto Rosati, Roberta La Starza, Angelo Veronese, Ana Aventin, Christine Schwienbacher, Teresa Vallespi, Massimo Negrini, Massimo F Martelli, Cristina Mecucci. Blood 2002
132
21

NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines.
P O Angrand, F Apiou, A F Stewart, B Dutrillaux, R Losson, P Chambon. Genomics 2001
117
21

NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
Alex J Kuo, Peggie Cheung, Kaifu Chen, Barry M Zee, Mitomu Kioi, Josh Lauring, Yuanxin Xi, Ben Ho Park, Xiaobing Shi, Benjamin A Garcia,[...]. Mol Cell 2011
270
21

Histone lysine methyltransferases in biology and disease.
Dylan Husmann, Or Gozani. Nat Struct Mol Biol 2019
109
21

High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2.
Nathan P Coussens, Stephen C Kales, Mark J Henderson, Olivia W Lee, Kurumi Y Horiuchi, Yuren Wang, Qing Chen, Ekaterina Kuznetsova, Jianghong Wu, Sirisha Chakka,[...]. J Biol Chem 2018
29
21

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.
Renato Ferreira de Freitas, Yanli Liu, Magdalena M Szewczyk, Naimee Mehta, Fengling Li, David McLeod, Carlos Zepeda-Velázquez, David Dilworth, Ronan P Hanley, Elisa Gibson,[...]. J Med Chem 2021
11
54

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.
Chen Shen, Jonathan J Ipsaro, Junwei Shi, Joseph P Milazzo, Eric Wang, Jae-Seok Roe, Yutaka Suzuki, Darryl J Pappin, Leemor Joshua-Tor, Christopher R Vakoc. Mol Cell 2015
92
17

Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.
Anastasia Amato, Xavier Lucas, Alessio Bortoluzzi, David Wright, Alessio Ciulli. ACS Chem Biol 2018
12
41

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.
Chunyan Ren, Keita Morohashi, Alexander N Plotnikov, Jean Jakoncic, Steven G Smith, Jiaojie Li, Lei Zeng, Yoel Rodriguez, Vivian Stojanoff, Martin Walsh,[...]. Chem Biol 2015
77
17

Targeting non-bromodomain chromatin readers.
Cheryl H Arrowsmith, Matthieu Schapira. Nat Struct Mol Biol 2019
24
20

Discovery of a chemical probe for PRDM9.
Abdellah Allali-Hassani, Magdalena M Szewczyk, Danton Ivanochko, Shawna L Organ, Jabez Bok, Jessica Sook Yuin Ho, Florence P H Gay, Fengling Li, Levi Blazer, Mohammad S Eram,[...]. Nat Commun 2019
14
35

Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.
Bowen Xu, Doan M On, Anqi Ma, Trevor Parton, Kyle D Konze, Samantha G Pattenden, David F Allison, Ling Cai, Shira Rockowitz, Shichong Liu,[...]. Blood 2015
150
17

NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.
Zheng Huang, Haiping Wu, Shannon Chuai, Fiona Xu, Feng Yan, Nathan Englund, Zhaofu Wang, Hailong Zhang, Ming Fang, Youzhen Wang,[...]. Cancer Res 2013
44
17

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.
Jacob D Jaffe, Yan Wang, Ho Man Chan, Jinghui Zhang, Robert Huether, Gregory V Kryukov, Hyo-eun C Bhang, Jordan E Taylor, Min Hu, Nathan P Englund,[...]. Nat Genet 2013
172
17

NSD1 is essential for early post-implantation development and has a catalytically active SET domain.
Geetha Vani Rayasam, Olivia Wendling, Pierre-Olivier Angrand, Manuel Mark, Karen Niederreither, Luyan Song, Thierry Lerouge, Gordon L Hager, Pierre Chambon, Régine Losson. EMBO J 2003
244
17

Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
Gang Yuan, Natasha M Flores, Simone Hausmann, Shane M Lofgren, Vladlena Kharchenko, Maria Angulo-Ibanez, Deepanwita Sengupta, Xiaoyin Lu, Iwona Czaban, Dulat Azhibek,[...]. Nature 2021
29
17

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
David Dilworth, Ronan P Hanley, Renato Ferreira de Freitas, Abdellah Allali-Hassani, Mengqi Zhou, Naimee Mehta, Matthew R Marunde, Suzanne Ackloo, Raquel Arminda Carvalho Machado, Aliakbar Khalili Yazdi,[...]. Nat Chem Biol 2022
8
62

Twenty years on: the impact of fragments on drug discovery.
Daniel A Erlanson, Stephen W Fesik, Roderick E Hubbard, Wolfgang Jahnke, Harren Jhoti. Nat Rev Drug Discov 2016
433
14

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Jacob I Stuckey, Bradley M Dickson, Nancy Cheng, Yanli Liu, Jacqueline L Norris, Stephanie H Cholensky, Wolfram Tempel, Su Qin, Katherine G Huber, Cari Sagum,[...]. Nat Chem Biol 2016
96
14

Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
Hacer Karatas, Yangbing Li, Liu Liu, Jiao Ji, Shirley Lee, Yong Chen, Jiuling Yang, Liyue Huang, Denzil Bernard, Jing Xu,[...]. J Med Chem 2017
49
14

Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform.
Tobias Wagner, Holger Greschik, Teresa Burgahn, Karin Schmidtkunz, Anne-Kathrin Schott, Joel McMillan, Lina Baranauskienė, Yan Xiong, Oleg Fedorov, Jian Jin,[...]. Nucleic Acids Res 2016
37
14

Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
Ramzi F Sweis, Marina Pliushchev, Peter J Brown, Jun Guo, Fengling Li, David Maag, Andrew M Petros, Nirupama B Soni, Chris Tse, Masoud Vedadi,[...]. ACS Med Chem Lett 2014
113
14

Small-molecule ligands of methyl-lysine binding proteins.
J Martin Herold, Tim J Wigle, Jacqueline L Norris, Robert Lam, Victoria K Korboukh, Cen Gao, Lindsey A Ingerman, Dmitri B Kireev, Guillermo Senisterra, Masoud Vedadi,[...]. J Med Chem 2011
87
14

Bromodomain biology and drug discovery.
Nilesh Zaware, Ming-Ming Zhou. Nat Struct Mol Biol 2019
79
14

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.
Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil,[...]. Nat Chem Biol 2015
156
14

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.
Lindsey I James, Dalia Barsyte-Lovejoy, Nan Zhong, Liubov Krichevsky, Victoria K Korboukh, J Martin Herold, Christopher J MacNevin, Jacqueline L Norris, Cari A Sagum, Wolfram Tempel,[...]. Nat Chem Biol 2013
114
14

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
Laetitia J Martin, Manfred Koegl, Gerd Bader, Xiao-Ling Cockcroft, Oleg Fedorov, Dennis Fiegen, Thomas Gerstberger, Marco H Hofmann, Anja F Hohmann, Dirk Kessler,[...]. J Med Chem 2016
115
14

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation.
Georg E Winter, Dennis L Buckley, Joshiawa Paulk, Justin M Roberts, Amanda Souza, Sirano Dhe-Paganon, James E Bradner. Science 2015
799
14

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
Michael T McCabe, Heidi M Ott, Gopinath Ganji, Susan Korenchuk, Christine Thompson, Glenn S Van Aller, Yan Liu, Alan P Graves, Anthony Della Pietra, Elsie Diaz,[...]. Nature 2012
14

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
656
14

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia.
Andrei V Krivtsov, Kathryn Evans, Jayant Y Gadrey, Benjamin K Eschle, Charlie Hatton, Hannah J Uckelmann, Kenneth N Ross, Florian Perner, Sarah N Olsen, Tara Pritchard,[...]. Cancer Cell 2019
126
14


Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Emily J Faivre, Keith F McDaniel, Daniel H Albert, Srinivasa R Mantena, Joshua P Plotnik, Denise Wilcox, Lu Zhang, Mai H Bui, George S Sheppard, Le Wang,[...]. Nature 2020
146
14

Transcription control by the ENL YEATS domain in acute leukaemia.
Michael A Erb, Thomas G Scott, Bin E Li, Huafeng Xie, Joshiawa Paulk, Hyuk-Soo Seo, Amanda Souza, Justin M Roberts, Shiva Dastjerdi, Dennis L Buckley,[...]. Nature 2017
149
14

Role of the polycomb protein EED in the propagation of repressive histone marks.
Raphael Margueron, Neil Justin, Katsuhito Ohno, Miriam L Sharpe, Jinsook Son, William J Drury, Philipp Voigt, Stephen R Martin, William R Taylor, Valeria De Marco,[...]. Nature 2009
769
14

The molecular hallmarks of epigenetic control.
C David Allis, Thomas Jenuwein. Nat Rev Genet 2016
14

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
Vincent Fagan, Catrine Johansson, Carina Gileadi, Octovia Monteiro, James E Dunford, Reshma Nibhani, Martin Philpott, Jessica Malzahn, Graham Wells, Ruth Faram,[...]. J Med Chem 2019
19
21

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Dmitry Borkin, Shihan He, Hongzhi Miao, Katarzyna Kempinska, Jonathan Pollock, Jennifer Chase, Trupta Purohit, Bhavna Malik, Ting Zhao, Jingya Wang,[...]. Cancer Cell 2015
211
14

Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader.
Frances Potjewyd, Anne-Marie W Turner, Joshua Beri, Justin M Rectenwald, Jacqueline L Norris-Drouin, Stephanie H Cholensky, David M Margolis, Kenneth H Pearce, Laura E Herring, Lindsey I James. Cell Chem Biol 2020
71
14

EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.
Jessie Hao-Ru Hsu, Timothy Rasmusson, James Robinson, Fiona Pachl, Jon Read, Sameer Kawatkar, Daniel H O' Donovan, Sharan Bagal, Erin Code, Philip Rawlins,[...]. Cell Chem Biol 2020
75
14

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.
Gang G Wang, Ling Cai, Martina P Pasillas, Mark P Kamps. Nat Cell Biol 2007
279
14

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
Sarah K Knutson, Tim J Wigle, Natalie M Warholic, Christopher J Sneeringer, Christina J Allain, Christine R Klaus, Joelle D Sacks, Alejandra Raimondi, Christina R Majer, Jeffrey Song,[...]. Nat Chem Biol 2012
567
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.