Madeline Halpern, Kristen J Brennand, James Gregory. Neurobiol Dis 2019
Times Cited: 11
Times Cited: 11
Times Cited
Times Co-cited
Similarity
Directed differentiation of embryonic stem cells into motor neurons.
Hynek Wichterle, Ivo Lieberam, Jeffery A Porter, Thomas M Jessell. Cell 2002
Hynek Wichterle, Ivo Lieberam, Jeffery A Porter, Thomas M Jessell. Cell 2002
45
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue,[...]. Nat Med 2018
Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue,[...]. Nat Med 2018
45
Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms.
Martin Madill, Katya McDonagh, Jun Ma, Alice Vajda, Paul McLoughlin, Timothy O'Brien, Orla Hardiman, Sanbing Shen. Mol Brain 2017
Martin Madill, Katya McDonagh, Jun Ma, Alice Vajda, Paul McLoughlin, Timothy O'Brien, Orla Hardiman, Sanbing Shen. Mol Brain 2017
36
Drug screening for ALS using patient-specific induced pluripotent stem cells.
Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita, Motoko Naitoh, Kazutoshi Takahashi, Takuya Yamamoto, Fumihiko Adachi, Takayuki Kondo, Keisuke Okita, Isao Asaka,[...]. Sci Transl Med 2012
Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita, Motoko Naitoh, Kazutoshi Takahashi, Takuya Yamamoto, Fumihiko Adachi, Takayuki Kondo, Keisuke Okita, Isao Asaka,[...]. Sci Transl Med 2012
36
Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Claire E Hall, Zhi Yao, Minee Choi, Giulia E Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J Crisp,[...]. Cell Rep 2017
Claire E Hall, Zhi Yao, Minee Choi, Giulia E Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J Crisp,[...]. Cell Rep 2017
36
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells.
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
Maria C N Marchetto, Alysson R Muotri, Yangling Mu, Alan M Smith, Gabriela G Cezar, Fred H Gage. Cell Stem Cell 2008
36
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
Brian J Wainger, Evangelos Kiskinis, Cassidy Mellin, Ole Wiskow, Steve S W Han, Jackson Sandoe, Numa P Perez, Luis A Williams, Seungkyu Lee, Gabriella Boulting,[...]. Cell Rep 2014
Brian J Wainger, Evangelos Kiskinis, Cassidy Mellin, Ole Wiskow, Steve S W Han, Jackson Sandoe, Numa P Perez, Luis A Williams, Seungkyu Lee, Gabriella Boulting,[...]. Cell Rep 2014
36
Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo.
Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J Maragakis, Guo-Li Ming, Hong Chen, Su-Chun Zhang. Stem Cell Reports 2017
Kun Qian, Hailong Huang, Andrew Peterson, Baoyang Hu, Nicholas J Maragakis, Guo-Li Ming, Hong Chen, Su-Chun Zhang. Stem Cell Reports 2017
36
Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
36
Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Chen Zhao, Anna-Claire Devlin, Amit K Chouhan, Bhuvaneish T Selvaraj, Maria Stavrou, Karen Burr, Veronica Brivio, Xin He, Arpan R Mehta, David Story,[...]. Glia 2020
Chen Zhao, Anna-Claire Devlin, Amit K Chouhan, Bhuvaneish T Selvaraj, Maria Stavrou, Karen Burr, Veronica Brivio, Xin He, Arpan R Mehta, David Story,[...]. Glia 2020
36
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
36
Genetic Convergence Brings Clarity to the Enigmatic Red Line in ALS.
Casey Cook, Leonard Petrucelli. Neuron 2019
Casey Cook, Leonard Petrucelli. Neuron 2019
36
ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
Rita Mejzini, Loren L Flynn, Ianthe L Pitout, Sue Fletcher, Steve D Wilton, P Anthony Akkari. Front Neurosci 2019
Rita Mejzini, Loren L Flynn, Ianthe L Pitout, Sue Fletcher, Steve D Wilton, P Anthony Akkari. Front Neurosci 2019
36
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.
Evangelos Kiskinis, Jackson Sandoe, Luis A Williams, Gabriella L Boulting, Rob Moccia, Brian J Wainger, Steve Han, Theodore Peng, Sebastian Thams, Shravani Mikkilineni,[...]. Cell Stem Cell 2014
Evangelos Kiskinis, Jackson Sandoe, Luis A Williams, Gabriella L Boulting, Rob Moccia, Brian J Wainger, Steve Han, Theodore Peng, Sebastian Thams, Shravani Mikkilineni,[...]. Cell Stem Cell 2014
27
Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons.
Hong Chen, Kun Qian, Zhongwei Du, Jingyuan Cao, Andrew Petersen, Huisheng Liu, Lisle W Blackbourn, CindyTzu-Ling Huang, Anthony Errigo, Yingnan Yin,[...]. Cell Stem Cell 2014
Hong Chen, Kun Qian, Zhongwei Du, Jingyuan Cao, Andrew Petersen, Huisheng Liu, Lisle W Blackbourn, CindyTzu-Ling Huang, Anthony Errigo, Yingnan Yin,[...]. Cell Stem Cell 2014
27
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
27
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
Ashley E Frakes, Laura Ferraiuolo, Amanda M Haidet-Phillips, Leah Schmelzer, Lyndsey Braun, Carlos J Miranda, Katherine J Ladner, Adam K Bevan, Kevin D Foust, Jonathan P Godbout,[...]. Neuron 2014
27
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
Francesco Paolo Di Giorgio, Monica A Carrasco, Michelle C Siao, Tom Maniatis, Kevin Eggan. Nat Neurosci 2007
27
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
Francesco Paolo Di Giorgio, Gabriella L Boulting, Samuel Bobrowicz, Kevin C Eggan. Cell Stem Cell 2008
27
Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS.
André Varcianna, Monika A Myszczynska, Lydia M Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R Heath, Matthew J Stopford,[...]. EBioMedicine 2019
André Varcianna, Monika A Myszczynska, Lydia M Castelli, Brendan O'Neill, Yeseul Kim, Jordan Talbot, Sophie Nyberg, Immanuelle Nyamali, Paul R Heath, Matthew J Stopford,[...]. EBioMedicine 2019
27
Genomic analysis of reactive astrogliosis.
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
Jennifer L Zamanian, Lijun Xu, Lynette C Foo, Navid Nouri, Lu Zhou, Rona G Giffard, Ben A Barres. J Neurosci 2012
27
Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R Klim, A Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S Lopes, Karolyn Sassi Ogliari, Luis A Williams, Matthew Shear,[...]. Stem Cell Reports 2017
27
Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
27
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
27
Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial.
. Lancet Neurol 2017
. Lancet Neurol 2017
27
A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.
Giulia E Tyzack, Claire E Hall, Christopher R Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F Meyer, Giampietro Schiavo, Su-Chun Zhang, George M Gibbons,[...]. Nat Commun 2017
Giulia E Tyzack, Claire E Hall, Christopher R Sibley, Tomasz Cymes, Serhiy Forostyak, Giulia Carlino, Ione F Meyer, Giampietro Schiavo, Su-Chun Zhang, George M Gibbons,[...]. Nat Commun 2017
27
Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner,[...]. EBioMedicine 2019
Anastasya Birger, Israel Ben-Dor, Miri Ottolenghi, Tikva Turetsky, Yaniv Gil, Sahar Sweetat, Liat Perez, Vitali Belzer, Natania Casden, Debora Steiner,[...]. EBioMedicine 2019
27
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease.
Maria Maddalena Lino, Corinna Schneider, Pico Caroni. J Neurosci 2002
Maria Maddalena Lino, Corinna Schneider, Pico Caroni. J Neurosci 2002
27
Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS).
Leslie I Grad, Guy A Rouleau, John Ravits, Neil R Cashman. Cold Spring Harb Perspect Med 2017
Leslie I Grad, Guy A Rouleau, John Ravits, Neil R Cashman. Cold Spring Harb Perspect Med 2017
27
Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers.
Björn F Vahsen, Elizabeth Gray, Alexander G Thompson, Olaf Ansorge, Daniel C Anthony, Sally A Cowley, Kevin Talbot, Martin R Turner. Nat Rev Neurol 2021
Björn F Vahsen, Elizabeth Gray, Alexander G Thompson, Olaf Ansorge, Daniel C Anthony, Sally A Cowley, Kevin Talbot, Martin R Turner. Nat Rev Neurol 2021
27
Rising Stars: Astrocytes as a Therapeutic Target for ALS Disease.
Michal Izrael, Shalom Guy Slutsky, Michel Revel. Front Neurosci 2020
Michal Izrael, Shalom Guy Slutsky, Michel Revel. Front Neurosci 2020
27
Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
Akshata A Almad, Arpitha Doreswamy, Sarah K Gross, Jean-Philippe Richard, Yuqing Huo, Norman Haughey, Nicholas J Maragakis. Glia 2016
18
Specification of motoneurons from human embryonic stem cells.
Xue-Jun Li, Zhong-Wei Du, Ewa D Zarnowska, Matthew Pankratz, Lauren O Hansen, Robert A Pearce, Su-Chun Zhang. Nat Biotechnol 2005
Xue-Jun Li, Zhong-Wei Du, Ewa D Zarnowska, Matthew Pankratz, Lauren O Hansen, Robert A Pearce, Su-Chun Zhang. Nat Biotechnol 2005
18
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Scott P Allen, Benjamin Hall, Lydia M Castelli, Laura Francis, Ryan Woof, Alexandros P Siskos, Eirini Kouloura, Elizabeth Gray, Alexander G Thompson, Kevin Talbot,[...]. Brain 2019
Scott P Allen, Benjamin Hall, Lydia M Castelli, Laura Francis, Ryan Woof, Alexandros P Siskos, Eirini Kouloura, Elizabeth Gray, Alexander G Thompson, Kevin Talbot,[...]. Brain 2019
18
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
Andrea Serio, Bilada Bilican, Sami J Barmada, Dale Michael Ando, Chen Zhao, Rick Siller, Karen Burr, Ghazal Haghi, David Story, Agnes Lumi Nishimura,[...]. Proc Natl Acad Sci U S A 2013
18
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Wenting Guo, Maximilian Naujock, Laura Fumagalli, Tijs Vandoorne, Pieter Baatsen, Ruben Boon, Laura Ordovás, Abdulsamie Patel, Marc Welters, Thomas Vanwelden,[...]. Nat Commun 2017
Wenting Guo, Maximilian Naujock, Laura Fumagalli, Tijs Vandoorne, Pieter Baatsen, Ruben Boon, Laura Ordovás, Abdulsamie Patel, Marc Welters, Thomas Vanwelden,[...]. Nat Commun 2017
18
Differentiation of spinal motor neurons from pluripotent human stem cells.
Bao-Yang Hu, Su-Chun Zhang. Nat Protoc 2009
Bao-Yang Hu, Su-Chun Zhang. Nat Protoc 2009
18
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.
Ze'ev Melamed, Jone López-Erauskin, Michael W Baughn, Ouyang Zhang, Kevin Drenner, Ying Sun, Fernande Freyermuth, Moira A McMahon, Melinda S Beccari, Jon W Artates,[...]. Nat Neurosci 2019
Ze'ev Melamed, Jone López-Erauskin, Michael W Baughn, Ouyang Zhang, Kevin Drenner, Ying Sun, Fernande Freyermuth, Moira A McMahon, Melinda S Beccari, Jon W Artates,[...]. Nat Neurosci 2019
18
Amyotrophic lateral sclerosis.
Orla Hardiman, Ammar Al-Chalabi, Adriano Chio, Emma M Corr, Giancarlo Logroscino, Wim Robberecht, Pamela J Shaw, Zachary Simmons, Leonard H van den Berg. Nat Rev Dis Primers 2017
Orla Hardiman, Ammar Al-Chalabi, Adriano Chio, Emma M Corr, Giancarlo Logroscino, Wim Robberecht, Pamela J Shaw, Zachary Simmons, Leonard H van den Berg. Nat Rev Dis Primers 2017
18
Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia.
Deepti Lall, Robert H Baloh. J Clin Invest 2017
Deepti Lall, Robert H Baloh. J Clin Invest 2017
18
Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.
Rodrigo Lopez-Gonzalez, Yubing Lu, Tania F Gendron, Anna Karydas, Helene Tran, Dejun Yang, Leonard Petrucelli, Bruce L Miller, Sandra Almeida, Fen-Biao Gao. Neuron 2016
Rodrigo Lopez-Gonzalez, Yubing Lu, Tania F Gendron, Anna Karydas, Helene Tran, Dejun Yang, Leonard Petrucelli, Bruce L Miller, Sandra Almeida, Fen-Biao Gao. Neuron 2016
18
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
Stuart M Chambers, Christopher A Fasano, Eirini P Papapetrou, Mark Tomishima, Michel Sadelain, Lorenz Studer. Nat Biotechnol 2009
18
Conversion of mouse and human fibroblasts into functional spinal motor neurons.
Esther Y Son, Justin K Ichida, Brian J Wainger, Jeremy S Toma, Victor F Rafuse, Clifford J Woolf, Kevin Eggan. Cell Stem Cell 2011
Esther Y Son, Justin K Ichida, Brian J Wainger, Jeremy S Toma, Victor F Rafuse, Clifford J Woolf, Kevin Eggan. Cell Stem Cell 2011
18
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
Kathrin Meyer, Laura Ferraiuolo, Carlos J Miranda, Shibi Likhite, Sohyun McElroy, Samantha Renusch, Dara Ditsworth, Clotilde Lagier-Tourenne, Richard A Smith, John Ravits,[...]. Proc Natl Acad Sci U S A 2014
18
The changing scene of amyotrophic lateral sclerosis.
Wim Robberecht, Thomas Philips. Nat Rev Neurosci 2013
Wim Robberecht, Thomas Philips. Nat Rev Neurosci 2013
18
Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosis.
Oliver J Ziff, Rickie Patani. Aging Cell 2019
Oliver J Ziff, Rickie Patani. Aging Cell 2019
18
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients.
Miguel Mitne-Neto, Marcela Machado-Costa, Maria C N Marchetto, Mario H Bengtson, Claudio A Joazeiro, Hiroshi Tsuda, Hugo J Bellen, Helga C A Silva, Acary S B Oliveira, Monize Lazar,[...]. Hum Mol Genet 2011
Miguel Mitne-Neto, Marcela Machado-Costa, Maria C N Marchetto, Mario H Bengtson, Claudio A Joazeiro, Hiroshi Tsuda, Hugo J Bellen, Helga C A Silva, Acary S B Oliveira, Monize Lazar,[...]. Hum Mol Genet 2011
18
Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.
Mark E Hester, Matthew J Murtha, SungWon Song, Meghan Rao, Carlos J Miranda, Kathrin Meyer, Jinbin Tian, Gabriella Boulting, David V Schaffer, Michael X Zhu,[...]. Mol Ther 2011
Mark E Hester, Matthew J Murtha, SungWon Song, Meghan Rao, Carlos J Miranda, Kathrin Meyer, Jinbin Tian, Gabriella Boulting, David V Schaffer, Michael X Zhu,[...]. Mol Ther 2011
18
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.
M E Ripps, G W Huntley, P R Hof, J H Morrison, J W Gordon. Proc Natl Acad Sci U S A 1995
M E Ripps, G W Huntley, P R Hof, J H Morrison, J W Gordon. Proc Natl Acad Sci U S A 1995
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.