J M Rothberg, D A Hartley, Z Walther, S Artavanis-Tsakonas. Cell 1988
Times Cited: 234
Times Cited: 234
Times Cited
Times Co-cited
Similarity
Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
50
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
47
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
46
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.
J M Rothberg, J R Jacobs, C S Goodman, S Artavanis-Tsakonas. Genes Dev 1990
J M Rothberg, J R Jacobs, C S Goodman, S Artavanis-Tsakonas. Genes Dev 1990
42
Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline.
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
M Seeger, G Tear, D Ferres-Marco, C S Goodman. Neuron 1993
33
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
24
Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
24
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
21
Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
20
Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration.
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
20
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
20
Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position.
J H Simpson, K S Bland, R D Fetter, C S Goodman. Cell 2000
J H Simpson, K S Bland, R D Fetter, C S Goodman. Cell 2000
18
Structural insights into the Slit-Robo complex.
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
18
Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching.
K H Wang, K Brose, D Arnott, T Kidd, C S Goodman, W Henzel, M Tessier-Lavigne. Cell 1999
K H Wang, K Brose, D Arnott, T Kidd, C S Goodman, W Henzel, M Tessier-Lavigne. Cell 1999
17
Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS.
S Rajagopalan, V Vivancos, E Nicolas, B J Dickson. Cell 2000
S Rajagopalan, V Vivancos, E Nicolas, B J Dickson. Cell 2000
17
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
17
Short-range and long-range guidance by slit and its Robo receptors. Robo and Robo2 play distinct roles in midline guidance.
J H Simpson, T Kidd, K S Bland, C S Goodman. Neuron 2000
J H Simpson, T Kidd, K S Bland, C S Goodman. Neuron 2000
16
Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
16
The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.
W Yuan, L Zhou, J H Chen, J Y Wu, Y Rao, D M Ornitz. Dev Biol 1999
W Yuan, L Zhou, J H Chen, J Y Wu, Y Rao, D M Ornitz. Dev Biol 1999
15
Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord.
T E Kennedy, T Serafini, J R de la Torre, M Tessier-Lavigne. Cell 1994
T E Kennedy, T Serafini, J R de la Torre, M Tessier-Lavigne. Cell 1994
15
Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
15
Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.
A Itoh, T Miyabayashi, M Ohno, S Sakano. Brain Res Mol Brain Res 1998
A Itoh, T Miyabayashi, M Ohno, S Sakano. Brain Res Mol Brain Res 1998
14
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.
T Serafini, T E Kennedy, M J Galko, C Mirzayan, T M Jessell, M Tessier-Lavigne. Cell 1994
T Serafini, T E Kennedy, M J Galko, C Mirzayan, T M Jessell, M Tessier-Lavigne. Cell 1994
14
Comm sorts robo to control axon guidance at the Drosophila midline.
Krystyna Keleman, Srikanth Rajagopalan, Diana Cleppien, David Teis, Karin Paiha, Lukas A Huber, Gerhard M Technau, Barry J Dickson. Cell 2002
Krystyna Keleman, Srikanth Rajagopalan, Diana Cleppien, David Teis, Karin Paiha, Lukas A Huber, Gerhard M Technau, Barry J Dickson. Cell 2002
14
Deleted in Colorectal Cancer (DCC) encodes a netrin receptor.
K Keino-Masu, M Masu, L Hinck, E D Leonardo, S S Chan, J G Culotti, M Tessier-Lavigne. Cell 1996
K Keino-Masu, M Masu, L Hinck, E D Leonardo, S S Chan, J G Culotti, M Tessier-Lavigne. Cell 1996
14
roundabout4 is essential for angiogenesis in vivo.
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
Victoria M Bedell, Sang-Yeob Yeo, Kye Won Park, Jeffrey Chung, Pankaj Seth, Venkatesha Shivalingappa, Jinhua Zhao, Tomoko Obara, Vikas P Sukhatme, Iain A Drummond,[...]. Proc Natl Acad Sci U S A 2005
14
Moving away from the midline: new developments for Slit and Robo.
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
Athena R Ypsilanti, Yvrick Zagar, Alain Chédotal. Development 2010
14
Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.
E Stein, M Tessier-Lavigne. Science 2001
E Stein, M Tessier-Lavigne. Science 2001
13
Guidance cues at the Drosophila CNS midline: identification and characterization of two Drosophila Netrin/UNC-6 homologs.
R Harris, L M Sabatelli, M A Seeger. Neuron 1996
R Harris, L M Sabatelli, M A Seeger. Neuron 1996
13
Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons.
K J Mitchell, J L Doyle, T Serafini, T E Kennedy, M Tessier-Lavigne, C S Goodman, B J Dickson. Neuron 1996
K J Mitchell, J L Doyle, T Serafini, T E Kennedy, M Tessier-Lavigne, C S Goodman, B J Dickson. Neuron 1996
13
Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance.
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
K T Nguyen Ba-Charvet, K Brose, L Ma, K H Wang, V Marillat, C Sotelo, M Tessier-Lavigne, A Chédotal. J Neurosci 2001
13
Conserved roles for Slit and Robo proteins in midline commissural axon guidance.
Hua Long, Christelle Sabatier, Le Ma, Andrew Plump, Wenlin Yuan, David M Ornitz, Atsushi Tamada, Fujio Murakami, Corey S Goodman, Marc Tessier-Lavigne. Neuron 2004
Hua Long, Christelle Sabatier, Le Ma, Andrew Plump, Wenlin Yuan, David M Ornitz, Atsushi Tamada, Fujio Murakami, Corey S Goodman, Marc Tessier-Lavigne. Neuron 2004
13
Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.
Zhe Liu, Kalpana Patel, Hannes Schmidt, William Andrews, Adrian Pini, Vasi Sundaresan. Mol Cell Neurosci 2004
Zhe Liu, Kalpana Patel, Hannes Schmidt, William Andrews, Adrian Pini, Vasi Sundaresan. Mol Cell Neurosci 2004
15
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.
Christelle Sabatier, Andrew S Plump, Le Ma, Katja Brose, Atsushi Tamada, Fujio Murakami, Eva Y-H P Lee, Marc Tessier-Lavigne. Cell 2004
Christelle Sabatier, Andrew S Plump, Le Ma, Katja Brose, Atsushi Tamada, Fujio Murakami, Eva Y-H P Lee, Marc Tessier-Lavigne. Cell 2004
13
Cables links Robo-bound Abl kinase to N-cadherin-bound beta-catenin to mediate Slit-induced modulation of adhesion and transcription.
Jinseol Rhee, Tim Buchan, Lawrence Zukerberg, Jack Lilien, Janne Balsamo. Nat Cell Biol 2007
Jinseol Rhee, Tim Buchan, Lawrence Zukerberg, Jack Lilien, Janne Balsamo. Nat Cell Biol 2007
13
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
15
Crossing the midline: roles and regulation of Robo receptors.
S Rajagopalan, E Nicolas, V Vivancos, J Berger, B J Dickson. Neuron 2000
S Rajagopalan, E Nicolas, V Vivancos, J Berger, B J Dickson. Neuron 2000
12
Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.
J Xian, K J Clark, R Fordham, R Pannell, T H Rabbitts, P H Rabbitts. Proc Natl Acad Sci U S A 2001
J Xian, K J Clark, R Fordham, R Pannell, T H Rabbitts, P H Rabbitts. Proc Natl Acad Sci U S A 2001
12
Robo1 and Robo2 are homophilic binding molecules that promote axonal growth.
Bruno Hivert, Zhe Liu, Ching-Yu Chuang, Patrick Doherty, Vasi Sundaresan. Mol Cell Neurosci 2002
Bruno Hivert, Zhe Liu, Ching-Yu Chuang, Patrick Doherty, Vasi Sundaresan. Mol Cell Neurosci 2002
12
Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions.
J M Rothberg, S Artavanis-Tsakonas. J Mol Biol 1992
J M Rothberg, S Artavanis-Tsakonas. J Mol Biol 1992
17
SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
12
Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells.
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
12
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
12
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
12
Axon repulsion from the midline of the Drosophila CNS requires slit function.
R Battye, A Stevens, J R Jacobs. Development 1999
R Battye, A Stevens, J R Jacobs. Development 1999
11
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system.
T Serafini, S A Colamarino, E D Leonardo, H Wang, R Beddington, W C Skarnes, M Tessier-Lavigne. Cell 1996
T Serafini, S A Colamarino, E D Leonardo, H Wang, R Beddington, W C Skarnes, M Tessier-Lavigne. Cell 1996
11
Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system.
Andrew S Plump, Lynda Erskine, Christelle Sabatier, Katja Brose, Charles J Epstein, Corey S Goodman, Carol A Mason, Marc Tessier-Lavigne. Neuron 2002
Andrew S Plump, Lynda Erskine, Christelle Sabatier, Katja Brose, Charles J Epstein, Corey S Goodman, Carol A Mason, Marc Tessier-Lavigne. Neuron 2002
11
Directional guidance of neuronal migration in the olfactory system by the protein Slit.
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.