Valentina Agnusdei, Sonia Minuzzo, Marica Pinazza, Alessandra Gasparini, Laura Pezzè, Adriana Agnese Amaro, Lorenza Pasqualini, Paola Del Bianco, Martina Tognon, Chiara Frasson, Pietro Palumbo, Yari Ciribilli, Ulrich Pfeffer, Massimo Carella, Alberto Amadori, Stefano Indraccolo. Haematologica 2020
Times Cited: 8
Times Cited: 8
Times Cited
Times Co-cited
Similarity
Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
50
A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
C Papayannidis, D J DeAngelo, W Stock, B Huang, M N Shaik, R Cesari, X Zheng, J M Reynolds, P A English, M Ozeck,[...]. Blood Cancer J 2015
37
The canonical Notch signaling pathway: unfolding the activation mechanism.
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
37
The genetics and mechanisms of T cell acute lymphoblastic leukaemia.
Laura Belver, Adolfo Ferrando. Nat Rev Cancer 2016
Laura Belver, Adolfo Ferrando. Nat Rev Cancer 2016
37
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
25
Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia.
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
Jeremy B Samon, Mireia Castillo-Martin, Michael Hadler, Alberto Ambesi-Impiobato, Elisabeth Paietta, Janis Racevskis, Peter H Wiernik, Jacob M Rowe, John Jakubczak, Sophia Randolph,[...]. Mol Cancer Ther 2012
25
Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
25
Oncogenic Notch signaling in T-cell and B-cell lymphoproliferative disorders.
Mark Y Chiang, Vedran Radojcic, Ivan Maillard. Curr Opin Hematol 2016
Mark Y Chiang, Vedran Radojcic, Ivan Maillard. Curr Opin Hematol 2016
25
Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.
Mara E Pitulescu, Inga Schmidt, Benedetto Daniele Giaimo, Tobiah Antoine, Frank Berkenfeld, Francesca Ferrante, Hongryeol Park, Manuel Ehling, Daniel Biljes, Susana F Rocha,[...]. Nat Cell Biol 2017
Mara E Pitulescu, Inga Schmidt, Benedetto Daniele Giaimo, Tobiah Antoine, Frank Berkenfeld, Francesca Ferrante, Hongryeol Park, Manuel Ehling, Daniel Biljes, Susana F Rocha,[...]. Nat Cell Biol 2017
25
The NOTCH Pathway and Its Mutations in Mature B Cell Malignancies.
Francesca Arruga, Tiziana Vaisitti, Silvia Deaglio. Front Oncol 2018
Francesca Arruga, Tiziana Vaisitti, Silvia Deaglio. Front Oncol 2018
25
Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
25
Leukemia-specific delivery of mutant NOTCH1 targeted therapy.
Giovanni Roti, Jun Qi, Samuel Kitara, Marta Sanchez-Martin, Amy Saur Conway, Anthony C Varca, Angela Su, Lei Wu, Andrew L Kung, Adolfo A Ferrando,[...]. J Exp Med 2018
Giovanni Roti, Jun Qi, Samuel Kitara, Marta Sanchez-Martin, Amy Saur Conway, Anthony C Varca, Angela Su, Lei Wu, Andrew L Kung, Adolfo A Ferrando,[...]. J Exp Med 2018
25
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
Giovanni Roti, Anne Carlton, Kenneth N Ross, Michele Markstein, Kostandin Pajcini, Angela H Su, Norbert Perrimon, Warren S Pear, Andrew L Kung, Stephen C Blacklow,[...]. Cancer Cell 2013
25
Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
Marta Sanchez-Martin, Alberto Ambesi-Impiombato, Yue Qin, Daniel Herranz, Mukesh Bansal, Tiziana Girardi, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Kim De Keersmaecker,[...]. Proc Natl Acad Sci U S A 2017
Marta Sanchez-Martin, Alberto Ambesi-Impiombato, Yue Qin, Daniel Herranz, Mukesh Bansal, Tiziana Girardi, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Kim De Keersmaecker,[...]. Proc Natl Acad Sci U S A 2017
25
γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde. EMBO Mol Med 2017
Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde. EMBO Mol Med 2017
25
The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia.
Rui D Mendes, Kirsten Canté-Barrett, Rob Pieters, Jules P P Meijerink. Haematologica 2016
Rui D Mendes, Kirsten Canté-Barrett, Rob Pieters, Jules P P Meijerink. Haematologica 2016
25
25
25
Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case.
Birgit Knoechel, Ami Bhatt, Li Pan, Chandra S Pedamallu, Eric Severson, Alejandro Gutierrez, David M Dorfman, Frank C Kuo, Michael Kluk, Andrew L Kung,[...]. Cold Spring Harb Mol Case Stud 2015
Birgit Knoechel, Ami Bhatt, Li Pan, Chandra S Pedamallu, Eric Severson, Alejandro Gutierrez, David M Dorfman, Frank C Kuo, Michael Kluk, Andrew L Kung,[...]. Cold Spring Harb Mol Case Stud 2015
25
Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
Kathleen Cullion, Kyle M Draheim, Nicole Hermance, Jennifer Tammam, Vishva M Sharma, Christopher Ware, George Nikov, Veena Krishnamoorthy, Pradip K Majumder, Michelle A Kelliher. Blood 2009
Kathleen Cullion, Kyle M Draheim, Nicole Hermance, Jennifer Tammam, Vishva M Sharma, Christopher Ware, George Nikov, Veena Krishnamoorthy, Pradip K Majumder, Michelle A Kelliher. Blood 2009
25
The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
Sung Hee Choi, Eric Severson, Warren S Pear, Xiaole S Liu, Jon C Aster, Stephen C Blacklow. PLoS One 2017
Sung Hee Choi, Eric Severson, Warren S Pear, Xiaole S Liu, Jon C Aster, Stephen C Blacklow. PLoS One 2017
25
A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors.
Ankur Sharma, Rupali A Gadkari, Satthenapalli V Ramakanth, Krishnanand Padmanabhan, Davanam S Madhumathi, Lakshmi Devi, Lingappa Appaji, Jon C Aster, Annapoorni Rangarajan, Rajan R Dighe. Sci Rep 2015
Ankur Sharma, Rupali A Gadkari, Satthenapalli V Ramakanth, Krishnanand Padmanabhan, Davanam S Madhumathi, Lakshmi Devi, Lingappa Appaji, Jon C Aster, Annapoorni Rangarajan, Rajan R Dighe. Sci Rep 2015
25
BMI1 Inhibitors Down-regulate NOTCH Signaling and Suppress Proliferation of Acute Leukemia Cells.
Mika Ohtaka, Mai Itoh, Shuji Tohda. Anticancer Res 2017
Mika Ohtaka, Mai Itoh, Shuji Tohda. Anticancer Res 2017
25
Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E Kohl, Victoria M Richon,[...]. Cancer Res 2009
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E Kohl, Victoria M Richon,[...]. Cancer Res 2009
25
Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.
Ila Joshi, Lisa M Minter, Janice Telfer, Renée M Demarest, Anthony J Capobianco, Jon C Aster, Piotr Sicinski, Abdul Fauq, Todd E Golde, Barbara A Osborne. Blood 2009
Ila Joshi, Lisa M Minter, Janice Telfer, Renée M Demarest, Anthony J Capobianco, Jon C Aster, Piotr Sicinski, Abdul Fauq, Todd E Golde, Barbara A Osborne. Blood 2009
25
Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
25
Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke, David Nittner, Rajeshwar Narlawar, Sofie Demeyer, James Dooley, Adrian Liston,[...]. Sci Transl Med 2019
25
The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
25
How I treat T-cell acute lymphoblastic leukemia in adults.
Mark R Litzow, Adolfo A Ferrando. Blood 2015
Mark R Litzow, Adolfo A Ferrando. Blood 2015
25
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
25
Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Kim De Keersmaecker, Michael Hadler, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Carles Forne, Montserrat Rue, Adolfo A Ferrando. Blood 2013
Pieter Van Vlierberghe, Alberto Ambesi-Impiombato, Kim De Keersmaecker, Michael Hadler, Elisabeth Paietta, Martin S Tallman, Jacob M Rowe, Carles Forne, Montserrat Rue, Adolfo A Ferrando. Blood 2013
25
Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments.
Rainer Breitling, Patrick Armengaud, Anna Amtmann, Pawel Herzyk. FEBS Lett 2004
Rainer Breitling, Patrick Armengaud, Anna Amtmann, Pawel Herzyk. FEBS Lett 2004
12
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma.
Richard I Fisher, Steven H Bernstein, Brad S Kahl, Benjamin Djulbegovic, Michael J Robertson, Sven de Vos, Elliot Epner, Amrita Krishnan, John P Leonard, Sagar Lonial,[...]. J Clin Oncol 2006
Richard I Fisher, Steven H Bernstein, Brad S Kahl, Benjamin Djulbegovic, Michael J Robertson, Sven de Vos, Elliot Epner, Amrita Krishnan, John P Leonard, Sagar Lonial,[...]. J Clin Oncol 2006
12
The Notch ligand DLL4 specifically marks human hematoendothelial progenitors and regulates their hematopoietic fate.
V Ayllón, C Bueno, V Ramos-Mejía, O Navarro-Montero, C Prieto, P J Real, T Romero, M J García-León, M L Toribio, A Bigas,[...]. Leukemia 2015
V Ayllón, C Bueno, V Ramos-Mejía, O Navarro-Montero, C Prieto, P J Real, T Romero, M J García-León, M L Toribio, A Bigas,[...]. Leukemia 2015
12
Volcano plots in analyzing differential expressions with mRNA microarrays.
Wentian Li. J Bioinform Comput Biol 2012
Wentian Li. J Bioinform Comput Biol 2012
12
Notch signaling, gamma-secretase inhibitors, and cancer therapy.
Ie-Ming Shih, Tian-Li Wang. Cancer Res 2007
Ie-Ming Shih, Tian-Li Wang. Cancer Res 2007
12
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.
Sílvia Beà, Rafael Valdés-Mas, Alba Navarro, Itziar Salaverria, David Martín-Garcia, Pedro Jares, Eva Giné, Magda Pinyol, Cristina Royo, Ferran Nadeu,[...]. Proc Natl Acad Sci U S A 2013
Sílvia Beà, Rafael Valdés-Mas, Alba Navarro, Itziar Salaverria, David Martín-Garcia, Pedro Jares, Eva Giné, Magda Pinyol, Cristina Royo, Ferran Nadeu,[...]. Proc Natl Acad Sci U S A 2013
12
Notch Signaling Pathway Regulates Angiogenesis via Endothelial Cell in 3D Co-Culture Model.
Dan Zhao, Changyue Xue, Shiyu Lin, Sirong Shi, Qianshun Li, Mengting Liu, Xiaoxiao Cai, Yunfeng Lin. J Cell Physiol 2017
Dan Zhao, Changyue Xue, Shiyu Lin, Sirong Shi, Qianshun Li, Mengting Liu, Xiaoxiao Cai, Yunfeng Lin. J Cell Physiol 2017
12
The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.
L T Krebs, M L Deftos, M J Bevan, T Gridley. Dev Biol 2001
L T Krebs, M L Deftos, M J Bevan, T Gridley. Dev Biol 2001
12
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors.
Franziska Meier-Stiegen, Ralf Schwanbeck, Kristina Bernoth, Simone Martini, Thomas Hieronymus, David Ruau, Martin Zenke, Ursula Just. PLoS One 2010
Franziska Meier-Stiegen, Ralf Schwanbeck, Kristina Bernoth, Simone Martini, Thomas Hieronymus, David Ruau, Martin Zenke, Ursula Just. PLoS One 2010
12
Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1.
L Mirandola, L Apicella, M Colombo, Y Yu, D G Berta, N Platonova, E Lazzari, M Lancellotti, G Bulfamante, E Cobos,[...]. Leukemia 2013
L Mirandola, L Apicella, M Colombo, Y Yu, D G Berta, N Platonova, E Lazzari, M Lancellotti, G Bulfamante, E Cobos,[...]. Leukemia 2013
12
Overexpression of B cell-specific activator protein (BSAP/Pax-5) in a late B cell is sufficient to suppress differentiation to an Ig high producer cell with plasma cell phenotype.
T Usui, Y Wakatsuki, Y Matsunaga, S Kaneko, H Koseki, T Kita. J Immunol 1997
T Usui, Y Wakatsuki, Y Matsunaga, S Kaneko, H Koseki, T Kita. J Immunol 1997
12
Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance.
Zhongwei Cao, Bi-Sen Ding, Peipei Guo, Sharrell B Lee, Jason M Butler, Stephanie C Casey, Michael Simons, Wayne Tam, Dean W Felsher, Koji Shido,[...]. Cancer Cell 2014
Zhongwei Cao, Bi-Sen Ding, Peipei Guo, Sharrell B Lee, Jason M Butler, Stephanie C Casey, Michael Simons, Wayne Tam, Dean W Felsher, Koji Shido,[...]. Cancer Cell 2014
12
Notch signaling: its roles and therapeutic potential in hematological malignancies.
Yisu Gu, Massimo Masiero, Alison H Banham. Oncotarget 2016
Yisu Gu, Massimo Masiero, Alison H Banham. Oncotarget 2016
12
A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer.
X Q Yan, U Sarmiento, Y Sun, G Huang, J Guo, T Juan, G Van, M Y Qi, S Scully, G Senaldi,[...]. Blood 2001
X Q Yan, U Sarmiento, Y Sun, G Huang, J Guo, T Juan, G Van, M Y Qi, S Scully, G Senaldi,[...]. Blood 2001
12
Loss of IRF8 Inhibits the Growth of Diffuse Large B-cell Lymphoma.
Yulian Xu, Lei Jiang, Jianchen Fang, Rong Fang, Herbert C Morse, Guifang Ouyang, Jeff X Zhou. J Cancer 2015
Yulian Xu, Lei Jiang, Jianchen Fang, Rong Fang, Herbert C Morse, Guifang Ouyang, Jeff X Zhou. J Cancer 2015
12
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
12
Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma.
Elisabeth Höring, Arnau Montraveta, Simon Heine, Markus Kleih, Lea Schaaf, Matthias C Vöhringer, Anna Esteve-Arenys, Gael Roué, Dolors Colomer, Elias Campo,[...]. Br J Haematol 2017
Elisabeth Höring, Arnau Montraveta, Simon Heine, Markus Kleih, Lea Schaaf, Matthias C Vöhringer, Anna Esteve-Arenys, Gael Roué, Dolors Colomer, Elias Campo,[...]. Br J Haematol 2017
12
DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
Sonia Minuzzo, Valentina Agnusdei, Irene Pusceddu, Marica Pinazza, Lidia Moserle, Massimo Masiero, Elisabetta Rossi, Marika Crescenzi, Timothy Hoey, Maurilio Ponzoni,[...]. Carcinogenesis 2015
Sonia Minuzzo, Valentina Agnusdei, Irene Pusceddu, Marica Pinazza, Lidia Moserle, Massimo Masiero, Elisabetta Rossi, Marika Crescenzi, Timothy Hoey, Maurilio Ponzoni,[...]. Carcinogenesis 2015
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.