Rachel Dalton, Seung-Been Lee, Katrina G Claw, Bhagwat Prasad, Brian R Phillips, Danny D Shen, Lai Hong Wong, Mitch Fade, Matthew G McDonald, Maitreya J Dunham, Douglas M Fowler, Allan E Rettie, Erin Schuetz, Timothy A Thornton, Deborah A Nickerson, Andrea Gaedigk, Kenneth E Thummel, Erica L Woodahl. Clin Transl Sci 2020
Times Cited: 19
Times Cited: 19
Times Cited
Times Co-cited
Similarity
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
Andrea Gaedigk, Magnus Ingelman-Sundberg, Neil A Miller, J Steven Leeder, Michelle Whirl-Carrillo, Teri E Klein. Clin Pharmacol Ther 2018
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The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
A Gaedigk, S D Simon, R E Pearce, L D Bradford, M J Kennedy, J S Leeder. Clin Pharmacol Ther 2008
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PharmVar GeneFocus: CYP2D6.
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips,[...]. Clin Pharmacol Ther 2020
36
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
J K Hicks, J R Bishop, K Sangkuhl, D J Müller, Y Ji, S G Leckband, J S Leeder, R L Graham, D L Chiulli, A LLerena,[...]. Clin Pharmacol Ther 2015
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Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
Kelly E Caudle, Katrin Sangkuhl, Michelle Whirl-Carrillo, Jesse J Swen, Cyrine E Haidar, Teri E Klein, Roseann S Gammal, Mary V Relling, Stuart A Scott, Daniel L Hertz,[...]. Clin Transl Sci 2020
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
Matthew P Goetz, Katrin Sangkuhl, Henk-Jan Guchelaar, Matthias Schwab, Michael Province, Michelle Whirl-Carrillo, W Fraser Symmans, Howard L McLeod, Mark J Ratain, Hitoshi Zembutsu,[...]. Clin Pharmacol Ther 2018
31
Prediction of CYP2D6 phenotype from genotype across world populations.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri Klein, J Steven Leeder. Genet Med 2017
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Pharmacogenomics knowledge for personalized medicine.
M Whirl-Carrillo, E M McDonagh, J M Hebert, L Gong, K Sangkuhl, C F Thorn, R B Altman, T E Klein. Clin Pharmacol Ther 2012
M Whirl-Carrillo, E M McDonagh, J M Hebert, L Gong, K Sangkuhl, C F Thorn, R B Altman, T E Klein. Clin Pharmacol Ther 2012
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Physicochemical Properties, Biotransformation, and Transport Pathways of Established and Newly Approved Medications: A Systematic Review of the Top 200 Most Prescribed Drugs vs. the FDA-Approved Drugs Between 2005 and 2016.
Anitha Saravanakumar, Armin Sadighi, Rachel Ryu, Fatemeh Akhlaghi. Clin Pharmacokinet 2019
Anitha Saravanakumar, Armin Sadighi, Rachel Ryu, Fatemeh Akhlaghi. Clin Pharmacokinet 2019
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Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update.
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
J K Hicks, K Sangkuhl, J J Swen, V L Ellingrod, D J Müller, K Shimoda, J R Bishop, E D Kharasch, T C Skaar, A Gaedigk,[...]. Clin Pharmacol Ther 2017
26
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
K R Crews, A Gaedigk, H M Dunnenberger, J S Leeder, T E Klein, K E Caudle, C E Haidar, D D Shen, J T Callaghan, S Sadhasivam,[...]. Clin Pharmacol Ther 2014
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CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network.
M V Relling, T E Klein. Clin Pharmacol Ther 2011
M V Relling, T E Klein. Clin Pharmacol Ther 2011
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Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
Danxin Wang, Ming J Poi, Xiaochun Sun, Andrea Gaedigk, J Steven Leeder, Wolfgang Sadee. Hum Mol Genet 2014
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Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron.
G C Bell, K E Caudle, M Whirl-Carrillo, R J Gordon, K Hikino, C A Prows, A Gaedigk, Jag Agundez, S Sadhasivam, T E Klein,[...]. Clin Pharmacol Ther 2017
G C Bell, K E Caudle, M Whirl-Carrillo, R J Gordon, K Hikino, C A Prows, A Gaedigk, Jag Agundez, S Sadhasivam, T E Klein,[...]. Clin Pharmacol Ther 2017
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CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
Andrea Gaedigk, Greyson P Twist, J Steven Leeder. Pharmacogenomics 2012
21
Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal, Ulrich Broeckel, Gwendolyn A McMillin, Roberta Melis, Erin C Boone, Victoria M Pratt,[...]. J Mol Diagn 2019
21
Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics.
Andrea Gaedigk, Jean C Dinh, Hyunyoung Jeong, Bhagwat Prasad, J Steven Leeder. J Pers Med 2018
Andrea Gaedigk, Jean C Dinh, Hyunyoung Jeong, Bhagwat Prasad, J Steven Leeder. J Pers Med 2018
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CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.
Andrea Gaedigk, Uwe Fuhr, Charlene Johnson, L Anick Bérard, Dianne Bradford, J Steven Leeder. Pharmacogenomics 2010
Andrea Gaedigk, Uwe Fuhr, Charlene Johnson, L Anick Bérard, Dianne Bradford, J Steven Leeder. Pharmacogenomics 2010
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Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy.
Jacob T Brown, Jeffrey R Bishop, Katrin Sangkuhl, Erika L Nurmi, Daniel J Mueller, Jean C Dinh, Andrea Gaedigk, Teri E Klein, Kelly E Caudle, James T McCracken,[...]. Clin Pharmacol Ther 2019
Jacob T Brown, Jeffrey R Bishop, Katrin Sangkuhl, Erika L Nurmi, Daniel J Mueller, Jean C Dinh, Andrea Gaedigk, Teri E Klein, Kelly E Caudle, James T McCracken,[...]. Clin Pharmacol Ther 2019
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The Evolution of PharmVar.
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P Twist, Teri E Klein, Neil A Miller. Clin Pharmacol Ther 2019
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P Twist, Teri E Klein, Neil A Miller. Clin Pharmacol Ther 2019
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Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model.
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
Seung-Been Lee, Marsha M Wheeler, Karynne Patterson, Sean McGee, Rachel Dalton, Erica L Woodahl, Andrea Gaedigk, Kenneth E Thummel, Deborah A Nickerson. Genet Med 2019
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PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation.
Adam S Gordon, Robert S Fulton, Xiang Qin, Elaine R Mardis, Deborah A Nickerson, Steve Scherer. Pharmacogenet Genomics 2016
Adam S Gordon, Robert S Fulton, Xiang Qin, Elaine R Mardis, Deborah A Nickerson, Steve Scherer. Pharmacogenet Genomics 2016
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Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
Greyson P Twist, Andrea Gaedigk, Neil A Miller, Emily G Farrow, Laurel K Willig, Darrell L Dinwiddie, Josh E Petrikin, Sarah E Soden, Suzanne Herd, Margaret Gibson,[...]. NPJ Genom Med 2016
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Integrating rare genetic variants into pharmacogenetic drug response predictions.
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke. Hum Genomics 2018
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An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke. Pharmacogenomics J 2019
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Allelic decomposition and exact genotyping of highly polymorphic and structurally variant genes.
Ibrahim Numanagić, Salem Malikić, Michael Ford, Xiang Qin, Lorraine Toji, Milan Radovich, Todd C Skaar, Victoria M Pratt, Bonnie Berger, Steve Scherer,[...]. Nat Commun 2018
Ibrahim Numanagić, Salem Malikić, Michael Ford, Xiang Qin, Lorraine Toji, Milan Radovich, Todd C Skaar, Victoria M Pratt, Bonnie Berger, Steve Scherer,[...]. Nat Commun 2018
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Transfer learning enables prediction of CYP2D6 haplotype function.
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl. PLoS Comput Biol 2020
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Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy.
Kristine R Crews, Andrew A Monte, Rachel Huddart, Kelly E Caudle, Evan D Kharasch, Andrea Gaedigk, Henry M Dunnenberger, J Steven Leeder, John T Callaghan, Caroline Flora Samer,[...]. Clin Pharmacol Ther 2021
Kristine R Crews, Andrew A Monte, Rachel Huddart, Kelly E Caudle, Evan D Kharasch, Andrea Gaedigk, Henry M Dunnenberger, J Steven Leeder, John T Callaghan, Caroline Flora Samer,[...]. Clin Pharmacol Ther 2021
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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.
P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, P B Watkins, A Daly, S A Wrighton, S D Hall,[...]. Nat Genet 2001
P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, P B Watkins, A Daly, S A Wrighton, S D Hall,[...]. Nat Genet 2001
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Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
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Functional characterization of CYP2D6 enhancer polymorphisms.
Danxin Wang, Audrey C Papp, Xiaochun Sun. Hum Mol Genet 2015
Danxin Wang, Audrey C Papp, Xiaochun Sun. Hum Mol Genet 2015
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Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants.
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
Andrea Gaedigk, Lazara Karelia Montane Jaime, Joseph S Bertino, Anick Bérard, Victoria M Pratt, L Dianne Bradfordand, J Steven Leeder. Front Pharmacol 2010
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CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels.
Balmiki Ray, Eren Ozcagli, Wolfgang Sadee, Danxin Wang. Pharmacogenet Genomics 2019
Balmiki Ray, Eren Ozcagli, Wolfgang Sadee, Danxin Wang. Pharmacogenet Genomics 2019
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Single dose, CYP2D6 genotype-stratified pharmacokinetic study of atomoxetine in children with ADHD.
J T Brown, S M Abdel-Rahman, L van Haandel, A Gaedigk, Y S Lin, J S Leeder. Clin Pharmacol Ther 2016
J T Brown, S M Abdel-Rahman, L van Haandel, A Gaedigk, Y S Lin, J S Leeder. Clin Pharmacol Ther 2016
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Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.
Shu-Feng Zhou. Clin Pharmacokinet 2009
Shu-Feng Zhou. Clin Pharmacokinet 2009
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Pharmacogenetics: from bench to byte--an update of guidelines.
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
J J Swen, M Nijenhuis, A de Boer, L Grandia, A H Maitland-van der Zee, H Mulder, G A P J M Rongen, R H N van Schaik, T Schalekamp, D J Touw,[...]. Clin Pharmacol Ther 2011
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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke. Front Pharmacol 2018
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Functional characterization of wild-type and 49 CYP2D6 allelic variants for N-desmethyltamoxifen 4-hydroxylation activity.
Yuka Muroi, Takahiro Saito, Masamitsu Takahashi, Kanako Sakuyama, Yui Niinuma, Miyabi Ito, Chiharu Tsukada, Kiminori Ohta, Yasuyuki Endo, Akifumi Oda,[...]. Drug Metab Pharmacokinet 2014
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Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
Yao Yang, Mariana R Botton, Erick R Scott, Stuart A Scott. Pharmacogenomics 2017
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A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping.
David Twesigomwe, Galen E B Wright, Britt I Drögemöller, Jorge da Rocha, Zané Lombard, Scott Hazelhurst. NPJ Genom Med 2020
David Twesigomwe, Galen E B Wright, Britt I Drögemöller, Jorge da Rocha, Zané Lombard, Scott Hazelhurst. NPJ Genom Med 2020
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Andria L Del Tredici, Alka Malhotra, Matthew Dedek, Frank Espin, Dan Roach, Guang-Dan Zhu, Joseph Voland, Tanya A Moreno. Front Pharmacol 2018
Andria L Del Tredici, Alka Malhotra, Matthew Dedek, Frank Espin, Dan Roach, Guang-Dan Zhu, Joseph Voland, Tanya A Moreno. Front Pharmacol 2018
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Pharmacogenetics at Scale: An Analysis of the UK Biobank.
Gregory McInnes, Adam Lavertu, Katrin Sangkuhl, Teri E Klein, Michelle Whirl-Carrillo, Russ B Altman. Clin Pharmacol Ther 2021
Gregory McInnes, Adam Lavertu, Katrin Sangkuhl, Teri E Klein, Michelle Whirl-Carrillo, Russ B Altman. Clin Pharmacol Ther 2021
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Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.
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Pharmacogenomics.
Dan M Roden, Howard L McLeod, Mary V Relling, Marc S Williams, George A Mensah, Josh F Peterson, Sara L Van Driest. Lancet 2019
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Tamoxifen Pharmacogenetics and Metabolism: Results From the Prospective CYPTAM Study.
Anabel Sanchez-Spitman, Vincent Dezentjé, Jesse Swen, Dirk Jan A R Moes, Stefan Böhringer, Erdogan Batman, Edith van Druten, Carolien Smorenburg, Aart van Bochove, Anneke Zeillemaker,[...]. J Clin Oncol 2019
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10
Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen.
Werner Schroth, Matthew P Goetz, Ute Hamann, Peter A Fasching, Marcus Schmidt, Stefan Winter, Peter Fritz, Wolfgang Simon, Vera J Suman, Matthew M Ames,[...]. JAMA 2009
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Regulatory polymorphisms in CYP2C19 affecting hepatic expression.
Jonathan C Sanford, Yingying Guo, Wolfgang Sadee, Danxin Wang. Drug Metabol Drug Interact 2013
Jonathan C Sanford, Yingying Guo, Wolfgang Sadee, Danxin Wang. Drug Metabol Drug Interact 2013
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CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
Andrea Gaedigk, L Dianne Bradford, Sarah W Alander, J Steven Leeder. Drug Metab Dispos 2006
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Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants.
Lazara Karelia Montané Jaime, Anthony Lalla, Werner Steimer, Andrea Gaedigk. Pharmacogenomics 2013
Lazara Karelia Montané Jaime, Anthony Lalla, Werner Steimer, Andrea Gaedigk. Pharmacogenomics 2013
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.