Uri Ben-David, Angelika Amon. Nat Rev Genet 2020
Times Cited: 135
Times Cited: 135
Times Cited
Times Co-cited
Similarity
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Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
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Chromosomal instability drives metastasis through a cytosolic DNA response.
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Short- and long-term effects of chromosome mis-segregation and aneuploidy.
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cGAS surveillance of micronuclei links genome instability to innate immunity.
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Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells.
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Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells.
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Cellular Stress Associated with Aneuploidy.
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Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.
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The presence of extra chromosomes leads to genomic instability.
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Aneuploidy-induced cellular stresses limit autophagic degradation.
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Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast.
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Aneuploidy drives lethal progression in prostate cancer.
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p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies.
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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.
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Cancer cells preferentially lose small chromosomes.
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Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.
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The Multifaceted Role of Chromosomal Instability in Cancer and Its Microenvironment.
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Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells.
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Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.
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Aneuploidy acts both oncogenically and as a tumor suppressor.
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Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.