Michelle Gray. Adv Exp Med Biol 2019
Times Cited: 15
Times Cited: 15
Times Cited
Times Co-cited
Similarity
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
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Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
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Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model.
Tara E Wood, Joshua Barry, Zhenquin Yang, Carlos Cepeda, Michael S Levine, Michelle Gray. Hum Mol Genet 2019
Tara E Wood, Joshua Barry, Zhenquin Yang, Carlos Cepeda, Michael S Levine, Michelle Gray. Hum Mol Genet 2019
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Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.
Baljit S Khakh, Vahri Beaumont, Roger Cachope, Ignacio Munoz-Sanjuan, Steven A Goldman, Rosemarie Grantyn. Trends Neurosci 2017
Baljit S Khakh, Vahri Beaumont, Roger Cachope, Ignacio Munoz-Sanjuan, Steven A Goldman, Rosemarie Grantyn. Trends Neurosci 2017
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CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.
Su Yang, Renbao Chang, Huiming Yang, Ting Zhao, Yan Hong, Ha Eun Kong, Xiaobo Sun, Zhaohui Qin, Peng Jin, Shihua Li,[...]. J Clin Invest 2017
Su Yang, Renbao Chang, Huiming Yang, Ting Zhao, Yan Hong, Ha Eun Kong, Xiaobo Sun, Zhaohui Qin, Peng Jin, Shihua Li,[...]. J Clin Invest 2017
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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
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The Role of Microglia and Astrocytes in Huntington's Disease.
Thulani H Palpagama, Henry J Waldvogel, Richard L M Faull, Andrea Kwakowsky. Front Mol Neurosci 2019
Thulani H Palpagama, Henry J Waldvogel, Richard L M Faull, Andrea Kwakowsky. Front Mol Neurosci 2019
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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
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Mitochondria in Huntington's disease.
Maria Damiano, Laurie Galvan, Nicole Déglon, Emmanuel Brouillet. Biochim Biophys Acta 2010
Maria Damiano, Laurie Galvan, Nicole Déglon, Emmanuel Brouillet. Biochim Biophys Acta 2010
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26
Single-nucleus RNA-seq identifies Huntington disease astrocyte states.
Osama Al-Dalahmah, Alexander A Sosunov, A Shaik, Kenneth Ofori, Yang Liu, Jean Paul Vonsattel, Istvan Adorjan, Vilas Menon, James E Goldman. Acta Neuropathol Commun 2020
Osama Al-Dalahmah, Alexander A Sosunov, A Shaik, Kenneth Ofori, Yang Liu, Jean Paul Vonsattel, Istvan Adorjan, Vilas Menon, James E Goldman. Acta Neuropathol Commun 2020
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Astrocyte molecular signatures in Huntington's disease.
Blanca Diaz-Castro, Mohitkumar R Gangwani, Xinzhu Yu, Giovanni Coppola, Baljit S Khakh. Sci Transl Med 2019
Blanca Diaz-Castro, Mohitkumar R Gangwani, Xinzhu Yu, Giovanni Coppola, Baljit S Khakh. Sci Transl Med 2019
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Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.
Haiqun Jia, Judit Pallos, Vincent Jacques, Alice Lau, Bin Tang, Andrew Cooper, Adeela Syed, Judith Purcell, Yi Chen, Shefali Sharma,[...]. Neurobiol Dis 2012
Haiqun Jia, Judit Pallos, Vincent Jacques, Alice Lau, Bin Tang, Andrew Cooper, Adeela Syed, Judith Purcell, Yi Chen, Shefali Sharma,[...]. Neurobiol Dis 2012
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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
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Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications.
George Bartzokis, Po H Lu, Todd A Tishler, Sophia M Fong, Bolanle Oluwadara, J Paul Finn, Danny Huang, Yvette Bordelon, Jim Mintz, Susan Perlman. Neurochem Res 2007
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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
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Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
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Wild-type huntingtin plays a role in brain development and neuronal survival.
Anton Reiner, Ioannis Dragatsis, Scott Zeitlin, Daniel Goldowitz. Mol Neurobiol 2003
Anton Reiner, Ioannis Dragatsis, Scott Zeitlin, Daniel Goldowitz. Mol Neurobiol 2003
20
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
20
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
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Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.
Veronica J Garcia, David J Rushton, Colton M Tom, Nicholas D Allen, Paul J Kemp, Clive N Svendsen, Virginia B Mattis. Front Neurosci 2019
Veronica J Garcia, David J Rushton, Colton M Tom, Nicholas D Allen, Paul J Kemp, Clive N Svendsen, Virginia B Mattis. Front Neurosci 2019
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Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
20
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
20
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
20
Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.
Pia Rivetti di Val Cervo, Roman A Romanov, Giada Spigolon, Débora Masini, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Michael Feyder, Christian Pifl, Yi-Han Ng,[...]. Nat Biotechnol 2017
Pia Rivetti di Val Cervo, Roman A Romanov, Giada Spigolon, Débora Masini, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Michael Feyder, Christian Pifl, Yi-Han Ng,[...]. Nat Biotechnol 2017
20
CRISPR-Cas9-Mediated Genome Editing Increases Lifespan and Improves Motor Deficits in a Huntington's Disease Mouse Model.
Freja K Ekman, David S Ojala, Maroof M Adil, Paola A Lopez, David V Schaffer, Thomas Gaj. Mol Ther Nucleic Acids 2019
Freja K Ekman, David S Ojala, Maroof M Adil, Paola A Lopez, David V Schaffer, Thomas Gaj. Mol Ther Nucleic Acids 2019
20
Cortical circuit alterations precede motor impairments in Huntington's disease mice.
Johanna Burgold, Elena Katharina Schulz-Trieglaff, Kerstin Voelkl, Sara Gutiérrez-Ángel, Jakob Maximilian Bader, Fabian Hosp, Matthias Mann, Thomas Arzberger, Rüdiger Klein, Sabine Liebscher,[...]. Sci Rep 2019
Johanna Burgold, Elena Katharina Schulz-Trieglaff, Kerstin Voelkl, Sara Gutiérrez-Ángel, Jakob Maximilian Bader, Fabian Hosp, Matthias Mann, Thomas Arzberger, Rüdiger Klein, Sabine Liebscher,[...]. Sci Rep 2019
20
Huntingtin Lowering Strategies for Disease Modification in Huntington's Disease.
Sarah J Tabrizi, Rhia Ghosh, Blair R Leavitt. Neuron 2019
Sarah J Tabrizi, Rhia Ghosh, Blair R Leavitt. Neuron 2019
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Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis.
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
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Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
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Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
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Role of cerebral cortex in the neuropathology of Huntington's disease.
Ana M Estrada-Sánchez, George V Rebec. Front Neural Circuits 2013
Ana M Estrada-Sánchez, George V Rebec. Front Neural Circuits 2013
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The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
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Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
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Huntington's disease alters human neurodevelopment.
Monia Barnat, Mariacristina Capizzi, Esther Aparicio, Susana Boluda, Doris Wennagel, Radhia Kacher, Rayane Kassem, Sophie Lenoir, Fabienne Agasse, Barbara Y Braz,[...]. Science 2020
Monia Barnat, Mariacristina Capizzi, Esther Aparicio, Susana Boluda, Doris Wennagel, Radhia Kacher, Rayane Kassem, Sophie Lenoir, Fabienne Agasse, Barbara Y Braz,[...]. Science 2020
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The contribution of glial cells to Huntington's disease pathogenesis.
Daniel K Wilton, Beth Stevens. Neurobiol Dis 2020
Daniel K Wilton, Beth Stevens. Neurobiol Dis 2020
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Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease.
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Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Ian H Kratter, Hengameh Zahed, Alice Lau, Andrey S Tsvetkov, Aaron C Daub, Kurt F Weiberth, Xiaofeng Gu, Frédéric Saudou, Sandrine Humbert, X William Yang,[...]. J Clin Invest 2016
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What have we learned from gene expression profiles in Huntington's disease?
Tamara Seredenina, Ruth Luthi-Carter. Neurobiol Dis 2012
Tamara Seredenina, Ruth Luthi-Carter. Neurobiol Dis 2012
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Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death.
Sami Reijonen, Jyrki P Kukkonen, Alise Hyrskyluoto, Jenny Kivinen, Minna Kairisalo, Nobuyuki Takei, Dan Lindholm, Laura Korhonen. Cell Mol Life Sci 2010
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Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.
Junghee Lee, Bela Kosaras, Steve J Del Signore, Kerry Cormier, Ann McKee, Rajiv R Ratan, Neil W Kowall, Hoon Ryu. Acta Neuropathol 2011
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Alterations in synaptic function and plasticity in Huntington disease.
Amy I Smith-Dijak, Marja D Sepers, Lynn A Raymond. J Neurochem 2019
Amy I Smith-Dijak, Marja D Sepers, Lynn A Raymond. J Neurochem 2019
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Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system.
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Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
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Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy.
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Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.
Judit Pallos, Laszlo Bodai, Tamas Lukacsovich, Judith M Purcell, Joan S Steffan, Leslie Michels Thompson, J Lawrence Marsh. Hum Mol Genet 2008
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Network organization of the huntingtin proteomic interactome in mammalian brain.
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13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.