Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements.
Vaishali Aggarwal, Hardeep Singh Tuli, Ayşegül Varol, Falak Thakral, Mukerrem Betul Yerer, Katrin Sak, Mehmet Varol, Aklank Jain, Md Asaduzzaman Khan, Gautam Sethi. Biomolecules 2019
Times Cited: 261
Times Cited: 261
Times Cited
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
14
ROS in cancer therapy: the bright side of the moon.
Bruno Perillo, Marzia Di Donato, Antonio Pezone, Erika Di Zazzo, Pia Giovannelli, Giovanni Galasso, Gabriella Castoria, Antimo Migliaccio. Exp Mol Med 2020
Bruno Perillo, Marzia Di Donato, Antonio Pezone, Erika Di Zazzo, Pia Giovannelli, Giovanni Galasso, Gabriella Castoria, Antimo Migliaccio. Exp Mol Med 2020
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Targeting autophagy using natural compounds for cancer prevention and therapy.
Shuo Deng, Muthu K Shanmugam, Alan Prem Kumar, Celestial T Yap, Gautam Sethi, Anupam Bishayee. Cancer 2019
Shuo Deng, Muthu K Shanmugam, Alan Prem Kumar, Celestial T Yap, Gautam Sethi, Anupam Bishayee. Cancer 2019
7
ROS signalling in the biology of cancer.
Jennifer N Moloney, Thomas G Cotter. Semin Cell Dev Biol 2018
Jennifer N Moloney, Thomas G Cotter. Semin Cell Dev Biol 2018
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Modulation of oxidative stress as an anticancer strategy.
Chiara Gorrini, Isaac S Harris, Tak W Mak. Nat Rev Drug Discov 2013
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ROS function in redox signaling and oxidative stress.
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Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.
Dmitry B Zorov, Magdalena Juhaszova, Steven J Sollott. Physiol Rev 2014
Dmitry B Zorov, Magdalena Juhaszova, Steven J Sollott. Physiol Rev 2014
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Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention.
Devesh Tewari, Seyed Fazel Nabavi, Seyed Mohammad Nabavi, Antoni Sureda, Ammad Ahmad Farooqi, Atanas G Atanasov, Rosa Anna Vacca, Gautam Sethi, Anupam Bishayee. Pharmacol Res 2018
Devesh Tewari, Seyed Fazel Nabavi, Seyed Mohammad Nabavi, Antoni Sureda, Ammad Ahmad Farooqi, Atanas G Atanasov, Rosa Anna Vacca, Gautam Sethi, Anupam Bishayee. Pharmacol Res 2018
5
Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy.
Xiaoyun Dai, Jingwen Zhang, Frank Arfuso, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Alan Prem Kumar, Kwang Seok Ahn, Gautam Sethi. Exp Biol Med (Maywood) 2015
Xiaoyun Dai, Jingwen Zhang, Frank Arfuso, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Alan Prem Kumar, Kwang Seok Ahn, Gautam Sethi. Exp Biol Med (Maywood) 2015
5
Cell death: a review of the major forms of apoptosis, necrosis and autophagy.
Mark S D'Arcy. Cell Biol Int 2019
Mark S D'Arcy. Cell Biol Int 2019
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Natural Products as Sources of New Drugs from 1981 to 2014.
David J Newman, Gordon M Cragg. J Nat Prod 2016
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ROS and the DNA damage response in cancer.
Upadhyayula Sai Srinivas, Bryce W Q Tan, Balamurugan A Vellayappan, Anand D Jeyasekharan. Redox Biol 2019
Upadhyayula Sai Srinivas, Bryce W Q Tan, Balamurugan A Vellayappan, Anand D Jeyasekharan. Redox Biol 2019
5
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
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The multifaceted role of reactive oxygen species in tumorigenesis.
Anuradha Kirtonia, Gautam Sethi, Manoj Garg. Cell Mol Life Sci 2020
Anuradha Kirtonia, Gautam Sethi, Manoj Garg. Cell Mol Life Sci 2020
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Reprogramming of fatty acid metabolism in cancer.
Nikos Koundouros, George Poulogiannis. Br J Cancer 2020
Nikos Koundouros, George Poulogiannis. Br J Cancer 2020
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Activation of apoptosis signalling pathways by reactive oxygen species.
Maureen Redza-Dutordoir, Diana A Averill-Bates. Biochim Biophys Acta 2016
Maureen Redza-Dutordoir, Diana A Averill-Bates. Biochim Biophys Acta 2016
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Molecular Mechanisms of Action of Genistein in Cancer: Recent Advances.
Hardeep Singh Tuli, Muobarak Jaber Tuorkey, Falak Thakral, Katrin Sak, Manoj Kumar, Anil Kumar Sharma, Uttam Sharma, Aklank Jain, Vaishali Aggarwal, Anupam Bishayee. Front Pharmacol 2019
Hardeep Singh Tuli, Muobarak Jaber Tuorkey, Falak Thakral, Katrin Sak, Manoj Kumar, Anil Kumar Sharma, Uttam Sharma, Aklank Jain, Vaishali Aggarwal, Anupam Bishayee. Front Pharmacol 2019
4
4
Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway.
Chakrabhavi Dhananjaya Mohan, V Srinivasa, Shobith Rangappa, Lewis Mervin, Surender Mohan, Shardul Paricharak, Sefer Baday, Feng Li, Muthu K Shanmugam, Arunachalam Chinnathambi,[...]. PLoS One 2016
Chakrabhavi Dhananjaya Mohan, V Srinivasa, Shobith Rangappa, Lewis Mervin, Surender Mohan, Shardul Paricharak, Sefer Baday, Feng Li, Muthu K Shanmugam, Arunachalam Chinnathambi,[...]. PLoS One 2016
5
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma.
Xiaoyun Dai, Lingzhi Wang, Amudha Deivasigamni, Chung Yeng Looi, Chandrabose Karthikeyan, Piyush Trivedi, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Frank Arfuso, Arunasalam Dharmarajan,[...]. Oncotarget 2017
Xiaoyun Dai, Lingzhi Wang, Amudha Deivasigamni, Chung Yeng Looi, Chandrabose Karthikeyan, Piyush Trivedi, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Frank Arfuso, Arunasalam Dharmarajan,[...]. Oncotarget 2017
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Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer.
Muthu K Shanmugam, Sudha Warrier, Alan P Kumar, Gautam Sethi, Frank Arfuso. Curr Vasc Pharmacol 2017
Muthu K Shanmugam, Sudha Warrier, Alan P Kumar, Gautam Sethi, Frank Arfuso. Curr Vasc Pharmacol 2017
4
Isorhamnetin augments the anti-tumor effect of capecitabine through the negative regulation of NF-κB signaling cascade in gastric cancer.
Kanjoormana A Manu, Muthu K Shanmugam, Lalitha Ramachandran, Feng Li, Kodappully Sivaraman Siveen, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Frank Arfuso, Alan Prem Kumar,[...]. Cancer Lett 2015
Kanjoormana A Manu, Muthu K Shanmugam, Lalitha Ramachandran, Feng Li, Kodappully Sivaraman Siveen, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Frank Arfuso, Alan Prem Kumar,[...]. Cancer Lett 2015
4
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.
Kanjoormana A Manu, Muthu K Shanmugam, Feng Li, Luxi Chen, Kodappully Sivaraman Siveen, Kwang Seok Ahn, Alan Prem Kumar, Gautam Sethi. J Mol Med (Berl) 2014
Kanjoormana A Manu, Muthu K Shanmugam, Feng Li, Luxi Chen, Kodappully Sivaraman Siveen, Kwang Seok Ahn, Alan Prem Kumar, Gautam Sethi. J Mol Med (Berl) 2014
4
Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives.
Srimanta Patra, Soumya R Mishra, Bishnu P Behera, Kewal K Mahapatra, Debasna P Panigrahi, Chandra S Bhol, Prakash P Praharaj, Gautam Sethi, Samir K Patra, Sujit K Bhutia. Semin Cancer Biol 2022
Srimanta Patra, Soumya R Mishra, Bishnu P Behera, Kewal K Mahapatra, Debasna P Panigrahi, Chandra S Bhol, Prakash P Praharaj, Gautam Sethi, Samir K Patra, Sujit K Bhutia. Semin Cancer Biol 2022
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The emerging role of the Nrf2-Keap1 signaling pathway in cancer.
Melba C Jaramillo, Donna D Zhang. Genes Dev 2013
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Oxidative Stress: Harms and Benefits for Human Health.
Gabriele Pizzino, Natasha Irrera, Mariapaola Cucinotta, Giovanni Pallio, Federica Mannino, Vincenzo Arcoraci, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto. Oxid Med Cell Longev 2017
Gabriele Pizzino, Natasha Irrera, Mariapaola Cucinotta, Giovanni Pallio, Federica Mannino, Vincenzo Arcoraci, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto. Oxid Med Cell Longev 2017
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Reactive Oxygen Species: A Key Constituent in Cancer Survival.
Seema Kumari, Anil Kumar Badana, Murali Mohan G, Shailender G, RamaRao Malla. Biomark Insights 2018
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Redox-Mediated Mechanism of Chemoresistance in Cancer Cells.
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DEAD-box helicase DP103 defines metastatic potential of human breast cancers.
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Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model.
Kodappully Sivaraman Siveen, Kwang Seok Ahn, Tina H Ong, Muthu K Shanmugam, Feng Li, Wei Ney Yap, Alan Prem Kumar, Chee Wai Fong, Vinay Tergaonkar, Kam M Hui,[...]. Oncotarget 2014
Kodappully Sivaraman Siveen, Kwang Seok Ahn, Tina H Ong, Muthu K Shanmugam, Feng Li, Wei Ney Yap, Alan Prem Kumar, Chee Wai Fong, Vinay Tergaonkar, Kam M Hui,[...]. Oncotarget 2014
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Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression.
Yu Rou Puar, Muthu K Shanmugam, Lu Fan, Frank Arfuso, Gautam Sethi, Vinay Tergaonkar. Biomedicines 2018
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Emergence of Circulating MicroRNAs in Breast Cancer as Diagnostic and Therapeutic Efficacy Biomarkers.
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Molecular Mechanisms of Action of Tocotrienols in Cancer: Recent Trends and Advancements.
Vaishali Aggarwal, Dharambir Kashyap, Katrin Sak, Hardeep Singh Tuli, Aklank Jain, Ashun Chaudhary, Vivek Kumar Garg, Gautam Sethi, Mukerrem Betul Yerer. Int J Mol Sci 2019
Vaishali Aggarwal, Dharambir Kashyap, Katrin Sak, Hardeep Singh Tuli, Aklank Jain, Ashun Chaudhary, Vivek Kumar Garg, Gautam Sethi, Mukerrem Betul Yerer. Int J Mol Sci 2019
7
Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model.
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Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements.
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Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer.
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Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.