Nesli-Ece Sen, Aleksandar Arsovic, David Meierhofer, Susanne Brodesser, Carola Oberschmidt, Júlia Canet-Pons, Zeynep-Ece Kaya, Melanie-Vanessa Halbach, Suzana Gispert, Konrad Sandhoff, Georg Auburger. Int J Mol Sci 2019
Times Cited: 10
Times Cited: 10
Times Cited
Times Co-cited
Similarity
Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation.
Isabel Lastres-Becker, David Nonis, Florian Eich, Michael Klinkenberg, Myriam Gorospe, Peter Kötter, Fabrice A C Klein, Nancy Kedersha, Georg Auburger. Biochim Biophys Acta 2016
Isabel Lastres-Becker, David Nonis, Florian Eich, Michael Klinkenberg, Myriam Gorospe, Peter Kötter, Fabrice A C Klein, Nancy Kedersha, Georg Auburger. Biochim Biophys Acta 2016
60
Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.
Isabel Lastres-Becker, Susanne Brodesser, Dieter Lütjohann, Mekhman Azizov, Jana Buchmann, Edith Hintermann, Konrad Sandhoff, Annette Schürmann, Joachim Nowock, Georg Auburger. Hum Mol Genet 2008
Isabel Lastres-Becker, Susanne Brodesser, Dieter Lütjohann, Mekhman Azizov, Jana Buchmann, Edith Hintermann, Konrad Sandhoff, Annette Schürmann, Joachim Nowock, Georg Auburger. Hum Mol Genet 2008
60
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
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Antisense oligonucleotide therapy for spinocerebellar ataxia type 2.
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
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Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996
50
Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations.
David Meierhofer, Melanie Halbach, Nesli Ece Şen, Suzana Gispert, Georg Auburger. Mol Cell Proteomics 2016
David Meierhofer, Melanie Halbach, Nesli Ece Şen, Suzana Gispert, Georg Auburger. Mol Cell Proteomics 2016
50
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice.
Lindsay A Becker, Brenda Huang, Gregor Bieri, Rosanna Ma, David A Knowles, Paymaan Jafar-Nejad, James Messing, Hong Joo Kim, Armand Soriano, Georg Auburger,[...]. Nature 2017
Lindsay A Becker, Brenda Huang, Gregor Bieri, Rosanna Ma, David A Knowles, Paymaan Jafar-Nejad, James Messing, Hong Joo Kim, Armand Soriano, Georg Auburger,[...]. Nature 2017
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Ataxin-2 associates with rough endoplasmic reticulum.
Simone van de Loo, Florian Eich, David Nonis, Georg Auburger, Joachim Nowock. Exp Neurol 2009
Simone van de Loo, Florian Eich, David Nonis, Georg Auburger, Joachim Nowock. Exp Neurol 2009
50
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.
Nesli-Ece Sen, Júlia Canet-Pons, Melanie V Halbach, Aleksandar Arsovic, Ulrich Pilatus, Woon-Hyung Chae, Zeynep-Ece Kaya, Kay Seidel, Ewa Rollmann, Michel Mittelbronn,[...]. Neurobiol Dis 2019
Nesli-Ece Sen, Júlia Canet-Pons, Melanie V Halbach, Aleksandar Arsovic, Ulrich Pilatus, Woon-Hyung Chae, Zeynep-Ece Kaya, Kay Seidel, Ewa Rollmann, Michel Mittelbronn,[...]. Neurobiol Dis 2019
50
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.
Ute Nonhoff, Markus Ralser, Franziska Welzel, Ilaria Piccini, Daniela Balzereit, Marie-Laure Yaspo, Hans Lehrach, Sylvia Krobitsch. Mol Biol Cell 2007
Ute Nonhoff, Markus Ralser, Franziska Welzel, Ilaria Piccini, Daniela Balzereit, Marie-Laure Yaspo, Hans Lehrach, Sylvia Krobitsch. Mol Biol Cell 2007
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PAS kinase is activated by direct SNF1-dependent phosphorylation and mediates inhibition of TORC1 through the phosphorylation and activation of Pbp1.
Desiree DeMille, Bryan D Badal, J Brady Evans, Andrew D Mathis, Joseph F Anderson, Julianne H Grose. Mol Biol Cell 2015
Desiree DeMille, Bryan D Badal, J Brady Evans, Andrew D Mathis, Joseph F Anderson, Julianne H Grose. Mol Biol Cell 2015
40
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
M Fittschen, I Lastres-Becker, M V Halbach, E Damrath, S Gispert, M Azizov, M Walter, S Müller, G Auburger. Neurogenetics 2015
M Fittschen, I Lastres-Becker, M V Halbach, E Damrath, S Gispert, M Azizov, M Walter, S Müller, G Auburger. Neurogenetics 2015
40
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes.
Terrence F Satterfield, Leo J Pallanck. Hum Mol Genet 2006
Terrence F Satterfield, Leo J Pallanck. Hum Mol Genet 2006
40
An integrative approach to gain insights into the cellular function of human ataxin-2.
Markus Ralser, Mario Albrecht, Ute Nonhoff, Thomas Lengauer, Hans Lehrach, Sylvia Krobitsch. J Mol Biol 2005
Markus Ralser, Mario Albrecht, Ute Nonhoff, Thomas Lengauer, Hans Lehrach, Sylvia Krobitsch. J Mol Biol 2005
40
Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway.
Melanie Vanessa Halbach, Suzana Gispert, Tanja Stehning, Ewa Damrath, Michael Walter, Georg Auburger. Cerebellum 2017
Melanie Vanessa Halbach, Suzana Gispert, Tanja Stehning, Ewa Damrath, Michael Walter, Georg Auburger. Cerebellum 2017
40
Spinocerebellar ataxia 2 (SCA2): morphometric analyses in 11 autopsies.
R Estrada, J Galarraga, G Orozco, A Nodarse, G Auburger. Acta Neuropathol 1999
R Estrada, J Galarraga, G Orozco, A Nodarse, G Auburger. Acta Neuropathol 1999
40
Efficient Prevention of Neurodegenerative Diseases by Depletion of Starvation Response Factor Ataxin-2.
Georg Auburger, Nesli-Ece Sen, David Meierhofer, Ayşe-Nazlı Başak, Aaron D Gitler. Trends Neurosci 2017
Georg Auburger, Nesli-Ece Sen, David Meierhofer, Ayşe-Nazlı Başak, Aaron D Gitler. Trends Neurosci 2017
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Generation and characterization of Sca2 (ataxin-2) knockout mice.
Tim-Rasmus Kiehl, Alex Nechiporuk, Karla P Figueroa, Mark T Keating, Duong P Huynh, Stefan-M Pulst. Biochem Biophys Res Commun 2006
Tim-Rasmus Kiehl, Alex Nechiporuk, Karla P Figueroa, Mark T Keating, Duong P Huynh, Stefan-M Pulst. Biochem Biophys Res Commun 2006
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Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model.
Warunee Dansithong, Sharan Paul, Karla P Figueroa, Marc D Rinehart, Shaina Wiest, Lance T Pflieger, Daniel R Scoles, Stefan M Pulst. PLoS Genet 2015
Warunee Dansithong, Sharan Paul, Karla P Figueroa, Marc D Rinehart, Shaina Wiest, Lance T Pflieger, Daniel R Scoles, Stefan M Pulst. PLoS Genet 2015
30
Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor.
Daniel Z Bar, Chayki Charar, Jehudith Dorfman, Tam Yadid, Lionel Tafforeau, Denis L J Lafontaine, Yosef Gruenbaum. Proc Natl Acad Sci U S A 2016
Daniel Z Bar, Chayki Charar, Jehudith Dorfman, Tam Yadid, Lionel Tafforeau, Denis L J Lafontaine, Yosef Gruenbaum. Proc Natl Acad Sci U S A 2016
30
On the distribution of intranuclear and cytoplasmic aggregates in the brainstem of patients with spinocerebellar ataxia type 2 and 3.
Kay Seidel, Sonny Siswanto, Michaela Fredrich, Mohamed Bouzrou, Wilfred F A den Dunnen, Inci Özerden, Horst-Werner Korf, Bela Melegh, Jeroen J de Vries, Ewout R Brunt,[...]. Brain Pathol 2017
Kay Seidel, Sonny Siswanto, Michaela Fredrich, Mohamed Bouzrou, Wilfred F A den Dunnen, Inci Özerden, Horst-Werner Korf, Bela Melegh, Jeroen J de Vries, Ewout R Brunt,[...]. Brain Pathol 2017
30
Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7.
Udo Rüb, Ludger Schöls, Henry Paulson, Georg Auburger, Pawel Kermer, Joanna C Jen, Kay Seidel, Horst-Werner Korf, Thomas Deller. Prog Neurobiol 2013
Udo Rüb, Ludger Schöls, Henry Paulson, Georg Auburger, Pawel Kermer, Joanna C Jen, Kay Seidel, Horst-Werner Korf, Thomas Deller. Prog Neurobiol 2013
30
Quantitative Global Proteomics of Yeast PBP1 Deletion Mutants and Their Stress Responses Identifies Glucose Metabolism, Mitochondrial, and Stress Granule Changes.
Gunnar Seidel, David Meierhofer, Nesli-Ece Şen, Anika Guenther, Sylvia Krobitsch, Georg Auburger. J Proteome Res 2017
Gunnar Seidel, David Meierhofer, Nesli-Ece Şen, Anika Guenther, Sylvia Krobitsch, Georg Auburger. J Proteome Res 2017
30
Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients.
Teresa Lee, Yun R Li, Caroline Ingre, Markus Weber, Torsten Grehl, Ole Gredal, Mamede de Carvalho, Thomas Meyer, Ole-Björn Tysnes, Georg Auburger,[...]. Hum Mol Genet 2011
Teresa Lee, Yun R Li, Caroline Ingre, Markus Weber, Torsten Grehl, Ole Gredal, Mamede de Carvalho, Thomas Meyer, Ole-Björn Tysnes, Georg Auburger,[...]. Hum Mol Genet 2011
30
The modulation of Amyotrophic Lateral Sclerosis risk by ataxin-2 intermediate polyglutamine expansions is a specific effect.
Suzana Gispert, Alexander Kurz, Stefan Waibel, Peter Bauer, Inga Liepelt, Christof Geisen, Aaron D Gitler, Tim Becker, Markus Weber, Daniela Berg,[...]. Neurobiol Dis 2012
Suzana Gispert, Alexander Kurz, Stefan Waibel, Peter Bauer, Inga Liepelt, Christof Geisen, Aaron D Gitler, Tim Becker, Markus Weber, Daniela Berg,[...]. Neurobiol Dis 2012
30
Direct binding of Ataxin-2 to distinct elements in 3' UTRs promotes mRNA stability and protein expression.
Moe Yokoshi, Quan Li, Munetaka Yamamoto, Hitomi Okada, Yutaka Suzuki, Yukio Kawahara. Mol Cell 2014
Moe Yokoshi, Quan Li, Munetaka Yamamoto, Hitomi Okada, Yutaka Suzuki, Yukio Kawahara. Mol Cell 2014
30
ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.
Ewa Damrath, Melanie V Heck, Suzana Gispert, Mekhman Azizov, Joachim Nowock, Carola Seifried, Udo Rüb, Michael Walter, Georg Auburger. PLoS Genet 2012
Ewa Damrath, Melanie V Heck, Suzana Gispert, Mekhman Azizov, Joachim Nowock, Carola Seifried, Udo Rüb, Michael Walter, Georg Auburger. PLoS Genet 2012
30
Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.
Nesli Ece Sen, Jessica Drost, Suzana Gispert, Sylvia Torres-Odio, Ewa Damrath, Michael Klinkenberg, Hamid Hamzeiy, Gülden Akdal, Halil Güllüoğlu, A Nazlı Başak,[...]. Neurobiol Dis 2016
Nesli Ece Sen, Jessica Drost, Suzana Gispert, Sylvia Torres-Odio, Ewa Damrath, Michael Klinkenberg, Hamid Hamzeiy, Gülden Akdal, Halil Güllüoğlu, A Nazlı Başak,[...]. Neurobiol Dis 2016
30
Ataxin-2 modulates the levels of Grb2 and SRC but not ras signaling.
Jessica Drost, David Nonis, Florian Eich, Oliver Leske, Ewa Damrath, Ewout R Brunt, Isabel Lastres-Becker, Rolf Heumann, Joachim Nowock, Georg Auburger. J Mol Neurosci 2013
Jessica Drost, David Nonis, Florian Eich, Oliver Leske, Ewa Damrath, Ewout R Brunt, Isabel Lastres-Becker, Rolf Heumann, Joachim Nowock, Georg Auburger. J Mol Neurosci 2013
30
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
Sylvia Torres-Odio, Jana Key, Hans-Hermann Hoepken, Júlia Canet-Pons, Lucie Valek, Bastian Roller, Michael Walter, Blas Morales-Gordo, David Meierhofer, Patrick N Harter,[...]. J Neuroinflammation 2017
Sylvia Torres-Odio, Jana Key, Hans-Hermann Hoepken, Júlia Canet-Pons, Lucie Valek, Bastian Roller, Michael Walter, Blas Morales-Gordo, David Meierhofer, Patrick N Harter,[...]. J Neuroinflammation 2017
30
Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking.
David Nonis, Mirko H H Schmidt, Simone van de Loo, Florian Eich, Ivan Dikic, Joachim Nowock, Georg Auburger. Cell Signal 2008
David Nonis, Mirko H H Schmidt, Simone van de Loo, Florian Eich, Ivan Dikic, Joachim Nowock, Georg Auburger. Cell Signal 2008
30
dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1.
Ismael Al-Ramahi, Alma M Pérez, Janghoo Lim, Minghang Zhang, Rie Sorensen, Maria de Haro, Joana Branco, Stefan M Pulst, Huda Y Zoghbi, Juan Botas. PLoS Genet 2007
Ismael Al-Ramahi, Alma M Pérez, Janghoo Lim, Minghang Zhang, Rie Sorensen, Maria de Haro, Joana Branco, Stefan M Pulst, Huda Y Zoghbi, Juan Botas. PLoS Genet 2007
30
Ataxin-2 repeat-length variation and neurodegeneration.
Owen A Ross, Nicola J Rutherford, Matt Baker, Alexandra I Soto-Ortolaza, Minerva M Carrasquillo, Mariely DeJesus-Hernandez, Jennifer Adamson, Ma Li, Kathryn Volkening, Elizabeth Finger,[...]. Hum Mol Genet 2011
Owen A Ross, Nicola J Rutherford, Matt Baker, Alexandra I Soto-Ortolaza, Minerva M Carrasquillo, Mariely DeJesus-Hernandez, Jennifer Adamson, Ma Li, Kathryn Volkening, Elizabeth Finger,[...]. Hum Mol Genet 2011
30
Polyglutamine spinocerebellar ataxias - from genes to potential treatments.
Henry L Paulson, Vikram G Shakkottai, H Brent Clark, Harry T Orr. Nat Rev Neurosci 2017
Henry L Paulson, Vikram G Shakkottai, H Brent Clark, Harry T Orr. Nat Rev Neurosci 2017
30
Involvement of the cranial nerves and their nuclei in spinocerebellar ataxia type 2 (SCA2).
K Gierga, K Bürk, M Bauer, G Orozco Diaz, G Auburger, C Schultz, M Vuksic, L Schöls, R A I de Vos, H Braak,[...]. Acta Neuropathol 2005
K Gierga, K Bürk, M Bauer, G Orozco Diaz, G Auburger, C Schultz, M Vuksic, L Schöls, R A I de Vos, H Braak,[...]. Acta Neuropathol 2005
30
FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control.
Indulekha P Sudhakaran, Jens Hillebrand, Adrian Dervan, Sudeshna Das, Eimear E Holohan, Jörn Hülsmeier, Mihail Sarov, Roy Parker, K VijayRaghavan, Mani Ramaswami. Proc Natl Acad Sci U S A 2014
Indulekha P Sudhakaran, Jens Hillebrand, Adrian Dervan, Sudeshna Das, Eimear E Holohan, Jörn Hülsmeier, Mihail Sarov, Roy Parker, K VijayRaghavan, Mani Ramaswami. Proc Natl Acad Sci U S A 2014
30
The Ataxin-2 protein is required for microRNA function and synapse-specific long-term olfactory habituation.
Cathal McCann, Eimear E Holohan, Sudeshna Das, Adrian Dervan, Aoife Larkin, John Anthony Lee, Veronica Rodrigues, Roy Parker, Mani Ramaswami. Proc Natl Acad Sci U S A 2011
Cathal McCann, Eimear E Holohan, Sudeshna Das, Adrian Dervan, Aoife Larkin, John Anthony Lee, Veronica Rodrigues, Roy Parker, Mani Ramaswami. Proc Natl Acad Sci U S A 2011
30
Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration.
Sharan Paul, Warunee Dansithong, Karla P Figueroa, Daniel R Scoles, Stefan M Pulst. Nat Commun 2018
Sharan Paul, Warunee Dansithong, Karla P Figueroa, Daniel R Scoles, Stefan M Pulst. Nat Commun 2018
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Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis.
C Y Lin, C M Pfluger, R D Henderson, P A McCombe. J Neuroimmunol 2012
C Y Lin, C M Pfluger, R D Henderson, P A McCombe. J Neuroimmunol 2012
20
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.
Clévio Nóbrega, Liliana Mendonça, Adriana Marcelo, Antonin Lamazière, Sandra Tomé, Gaetan Despres, Carlos A Matos, Fatich Mechmet, Dominique Langui, Wilfred den Dunnen,[...]. Acta Neuropathol 2019
Clévio Nóbrega, Liliana Mendonça, Adriana Marcelo, Antonin Lamazière, Sandra Tomé, Gaetan Despres, Carlos A Matos, Fatich Mechmet, Dominique Langui, Wilfred den Dunnen,[...]. Acta Neuropathol 2019
20
20
Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2.
Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Pulst. Hum Mol Genet 2013
Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Pulst. Hum Mol Genet 2013
20
Purkinje Cell Signaling Deficits in Animal Models of Ataxia.
Eriola Hoxha, Ilaria Balbo, Maria Concetta Miniaci, Filippo Tempia. Front Synaptic Neurosci 2018
Eriola Hoxha, Ilaria Balbo, Maria Concetta Miniaci, Filippo Tempia. Front Synaptic Neurosci 2018
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Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.
Lodewijk J A Toonen, Maurice Overzier, Melvin M Evers, Leticia G Leon, Sander A J van der Zeeuw, Hailiang Mei, Szymon M Kielbasa, Jelle J Goeman, Kristina M Hettne, Olafur Th Magnusson,[...]. Mol Neurodegener 2018
Lodewijk J A Toonen, Maurice Overzier, Melvin M Evers, Leticia G Leon, Sander A J van der Zeeuw, Hailiang Mei, Szymon M Kielbasa, Jelle J Goeman, Kristina M Hettne, Olafur Th Magnusson,[...]. Mol Neurodegener 2018
20
Gene co-expression network analysis for identifying modules and functionally enriched pathways in SCA2.
Lance T Pflieger, Warunee Dansithong, Sharan Paul, Daniel R Scoles, Karla P Figueroa, Pratap Meera, Thomas S Otis, Julio C Facelli, Stefan M Pulst. Hum Mol Genet 2017
Lance T Pflieger, Warunee Dansithong, Sharan Paul, Daniel R Scoles, Karla P Figueroa, Pratap Meera, Thomas S Otis, Julio C Facelli, Stefan M Pulst. Hum Mol Genet 2017
20
Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond.
Alexandra Durr. Lancet Neurol 2010
Alexandra Durr. Lancet Neurol 2010
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Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT.
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Anatomically based guidelines for systematic investigation of the central somatosensory system and their application to a spinocerebellar ataxia type 2 (SCA2) patient.
U Rüb, C Schultz, K Del Tredici, K Gierga, G Reifenberger, R A I de Vos, C Seifried, H Braak, G Auburger. Neuropathol Appl Neurobiol 2003
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Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.