A citation-based method for searching scientific literature

Ming-Ming Hu, Hong-Bing Shu. Annu Rev Immunol 2020
Times Cited: 28







List of co-cited articles
246 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
50


The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Bo Zhong, Yan Yang, Shu Li, Yan-Yi Wang, Ying Li, Feici Diao, Caoqi Lei, Xiao He, Lu Zhang, Po Tien,[...]. Immunity 2008
852
28

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
263
28

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
170
25


Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
486
25

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
356
25

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
713
25

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Guijun Shang, Conggang Zhang, Zhijian J Chen, Xiao-Chen Bai, Xuewu Zhang. Nature 2019
138
25

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.
Siqi Liu, Xin Cai, Jiaxi Wu, Qian Cong, Xiang Chen, Tuo Li, Fenghe Du, Junyao Ren, You-Tong Wu, Nick V Grishin,[...]. Science 2015
683
25

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
221
25


Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
482
21

Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.
Sebastian Aguirre, Priya Luthra, Maria T Sanchez-Aparicio, Ana M Maestre, Jenish Patel, Francise Lamothe, Anthony C Fredericks, Shashank Tripathi, Tongtong Zhu, Jessica Pintado-Silva,[...]. Nat Microbiol 2017
165
21

Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids.
Ming-Ming Hu, Hong-Bing Shu. Annu Rev Cell Dev Biol 2018
41
21

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus.
Ming-Ming Hu, Qing Yang, Xue-Qin Xie, Chen-Yang Liao, Heng Lin, Tian-Tian Liu, Lei Yin, Hong-Bing Shu. Immunity 2016
166
21

Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
709
21

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Xiang Gui, Hui Yang, Tuo Li, Xiaojun Tan, Peiqing Shi, Minghao Li, Fenghe Du, Zhijian J Chen. Nature 2019
241
21


Molecular mechanisms and cellular functions of cGAS-STING signalling.
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
139
21

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
Elie J Diner, Dara L Burdette, Stephen C Wilson, Kathryn M Monroe, Colleen A Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C Hammond, Russell E Vance. Cell Rep 2013
413
17

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
265
17

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu,[...]. Nature 2019
70
17

STING is a direct innate immune sensor of cyclic di-GMP.
Dara L Burdette, Kathryn M Monroe, Katia Sotelo-Troha, Jeff S Iwig, Barbara Eckert, Mamoru Hyodo, Yoshihiro Hayakawa, Russell E Vance. Nature 2011
825
17

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.
James B Eaglesham, Youdong Pan, Thomas S Kupper, Philip J Kranzusch. Nature 2019
71
17

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
17

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
569
17

IFI16 is an innate immune sensor for intracellular DNA.
Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao,[...]. Nat Immunol 2010
17

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
585
17

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
170
17

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Katherine R Balka, Cynthia Louis, Tahnee L Saunders, Amber M Smith, Dale J Calleja, Damian B D'Silva, Fiona Moghaddas, Maximilien Tailler, Kate E Lawlor, Yifan Zhan,[...]. Cell Rep 2020
46
17

G3BP1 promotes DNA binding and activation of cGAS.
Zhao-Shan Liu, Hong Cai, Wen Xue, Miao Wang, Tian Xia, Wan-Jin Li, Jia-Qing Xing, Ming Zhao, Yi-Jiao Huang, Shuai Chen,[...]. Nat Immunol 2019
82
17

Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses.
Miyu Moriyama, Takumi Koshiba, Takeshi Ichinohe. Nat Commun 2019
30
17

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
Katherine C Barnett, Julia M Coronas-Serna, Wen Zhou, Michael J Ernandes, Anh Cao, Philip J Kranzusch, Jonathan C Kagan. Cell 2019
77
17

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.
Hannah E Volkman, Stephanie Cambier, Elizabeth E Gray, Daniel B Stetson. Elife 2019
78
17

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.
Xu Zhang, Jiaxi Wu, Fenghe Du, Hui Xu, Lijun Sun, Zhe Chen, Chad A Brautigam, Xuewu Zhang, Zhijian J Chen. Cell Rep 2014
196
14

Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis.
Yanyan Zheng, Qingxiang Liu, Yaoxing Wu, Ling Ma, Zhenzhen Zhang, Tao Liu, Shouheng Jin, Yuanchu She, Yi-Ping Li, Jun Cui. EMBO J 2018
59
14

Targeting STING with covalent small-molecule inhibitors.
Simone M Haag, Muhammet F Gulen, Luc Reymond, Antoine Gibelin, Laurence Abrami, Alexiane Decout, Michael Heymann, F Gisou van der Goot, Gerardo Turcatti, Rayk Behrendt,[...]. Nature 2018
210
14

Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response.
Yu-Zhi Fu, Yi Guo, Hong-Mei Zou, Shan Su, Su-Yun Wang, Qing Yang, Min-Hua Luo, Yan-Yi Wang. PLoS Pathog 2019
23
17

Activation of STING requires palmitoylation at the Golgi.
Kojiro Mukai, Hiroyasu Konno, Tatsuya Akiba, Takefumi Uemura, Satoshi Waguri, Toshihide Kobayashi, Glen N Barber, Hiroyuki Arai, Tomohiko Taguchi. Nat Commun 2016
179
14

Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.
Lingyin Li, Qian Yin, Pia Kuss, Zoltan Maliga, José L Millán, Hao Wu, Timothy J Mitchison. Nat Chem Biol 2014
168
14

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.
Wenxiang Sun, Yang Li, Lu Chen, Huihui Chen, Fuping You, Xiang Zhou, Yi Zhou, Zhonghe Zhai, Danying Chen, Zhengfan Jiang. Proc Natl Acad Sci U S A 2009
458
14

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.
Andrea Ablasser, Jonathan L Schmid-Burgk, Inga Hemmerling, Gabor L Horvath, Tobias Schmidt, Eicke Latz, Veit Hornung. Nature 2013
316
14

iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
Wei-Wei Luo, Shu Li, Chen Li, Huan Lian, Qing Yang, Bo Zhong, Hong-Bing Shu. Nat Immunol 2016
123
14

STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.
Nicole Dobbs, Nikolay Burnaevskiy, Didi Chen, Vijay K Gonugunta, Neal M Alto, Nan Yan. Cell Host Microbe 2015
210
14

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
199
14

Pathogen recognition and innate immunity.
Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi. Cell 2006
14

Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus.
Jie An, Laura Durcan, Reynold M Karr, Tracy A Briggs, Gillian I Rice, Thomas H Teal, Joshua J Woodward, Keith B Elkon. Arthritis Rheumatol 2017
71
14

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity.
John W Schoggins, Donna A MacDuff, Naoko Imanaka, Maria D Gainey, Bimmi Shrestha, Jennifer L Eitson, Katrina B Mar, R Blake Richardson, Alexander V Ratushny, Vladimir Litvak,[...]. Nature 2014
536
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.