A citation-based method for searching scientific literature

Hermann Koepsell. Pharmacol Rev 2020
Times Cited: 96







List of co-cited articles
978 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Membrane transporters in drug development.
Kathleen M Giacomini, Shiew-Mei Huang, Donald J Tweedie, Leslie Z Benet, Kim L R Brouwer, Xiaoyan Chu, Amber Dahlin, Raymond Evers, Volker Fischer, Kathleen M Hillgren,[...]. Nat Rev Drug Discov 2010
18

Cloning and characterization of two human polyspecific organic cation transporters.
V Gorboulev, J C Ulzheimer, A Akhoundova, I Ulzheimer-Teuber, U Karbach, S Quester, C Baumann, F Lang, A E Busch, H Koepsell. DNA Cell Biol 1997
502
18

Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency.
Mladen V Tzvetkov, Johannes Matthaei, Sherin Pojar, Frank Faltraco, Sabrina Vogler, Thomas Prukop, Tina Seitz, Jürgen Brockmöller. Clin Pharmacol Ther 2018
40
45

Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration.
Mladen V Tzvetkov, Joao N dos Santos Pereira, Ingolf Meineke, Ali R Saadatmand, Julia C Stingl, Jürgen Brockmöller. Biochem Pharmacol 2013
125
18

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.
Anne T Nies, Hermann Koepsell, Katja Damme, Matthias Schwab. Handb Exp Pharmacol 2011
266
17

Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates.
Philip J Sandoval, Kimberley M Zorn, Alex M Clark, Sean Ekins, Stephen H Wright. Mol Pharmacol 2018
51
31


Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.
Anne T Nies, Hermann Koepsell, Stefan Winter, Oliver Burk, Kathrin Klein, Reinhold Kerb, Ulrich M Zanger, Dietrich Keppler, Matthias Schwab, Elke Schaeffeler. Hepatology 2009
267
15

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Ligong Chen, Yan Shu, Xiaomin Liang, Eugene C Chen, Sook Wah Yee, Arik A Zur, Shuanglian Li, Lu Xu, Kayvan R Keshari, Michael J Lin,[...]. Proc Natl Acad Sci U S A 2014
139
15

OCT1 mediates hepatic uptake of sumatriptan and loss-of-function OCT1 polymorphisms affect sumatriptan pharmacokinetics.
J Matthaei, D Kuron, F Faltraco, T Knoch, J N Dos Santos Pereira, M Abu Abed, T Prukop, J Brockmöller, M V Tzvetkov. Clin Pharmacol Ther 2016
58
25

Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine.
A E Busch, U Karbach, D Miska, V Gorboulev, A Akhoundova, C Volk, P Arndt, J C Ulzheimer, M S Sonders, C Baumann,[...]. Mol Pharmacol 1998
258
15


An unsuspected role for organic cation transporter 3 in the actions of amphetamine.
Felix P Mayer, Diethart Schmid, W Anthony Owens, Georgianna G Gould, Mia Apuschkin, Oliver Kudlacek, Isabella Salzer, Stefan Boehm, Peter Chiba, Piper H Williams,[...]. Neuropsychopharmacology 2018
32
43

Altered aminergic neurotransmission in the brain of organic cation transporter 3-deficient mice.
Vincent Vialou, Laure Balasse, Jacques Callebert, Jean-Marie Launay, Bruno Giros, Sophie Gautron. J Neurochem 2008
69
20


Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Gustav Ahlin, Johan Karlsson, Jenny M Pedersen, Lena Gustavsson, Rolf Larsson, Pär Matsson, Ulf Norinder, Christel A S Bergström, Per Artursson. J Med Chem 2008
129
14

Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
Eugene C Chen, Natalia Khuri, Xiaomin Liang, Adrian Stecula, Huan-Chieh Chien, Sook Wah Yee, Yong Huang, Andrej Sali, Kathleen M Giacomini. J Med Chem 2017
31
45


Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain.
Anne Amphoux, Vincent Vialou, Eva Drescher, Michael Brüss, Clotilde Mannoury La Cour, Catherine Rochat, Mark J Millan, Bruno Giros, Heinz Bönisch, Sophie Gautron. Neuropharmacology 2006
150
13

Drug excretion mediated by a new prototype of polyspecific transporter.
D Gründemann, V Gorboulev, S Gambaryan, M Veyhl, H Koepsell. Nature 1994
544
12


Substrate-dependent ligand inhibition of the human organic cation transporter OCT2.
Mathew Belzer, Mark Morales, Bhumasamudram Jagadish, Eugene A Mash, Stephen H Wright. J Pharmacol Exp Ther 2013
70
17

Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter.
Rheaclare Fraser-Spears, Anwen M Krause-Heuer, Mohamed Basiouny, Felix P Mayer, Retrouvailles Manishimwe, Naomi A Wyatt, Jeremy C Dobrowolski, Maxine P Roberts, Ivan Greguric, Naresh Kumar,[...]. Eur J Pharmacol 2019
20
60

Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1.
Tina Seitz, Robert Stalmann, Nawar Dalila, Jiayin Chen, Sherin Pojar, Joao N Dos Santos Pereira, Ralph Krätzner, Jürgen Brockmöller, Mladen V Tzvetkov. Genome Med 2015
61
19

Organic cation transporter 2 controls brain norepinephrine and serotonin clearance and antidepressant response.
A Bacq, L Balasse, G Biala, B Guiard, A M Gardier, A Schinkel, F Louis, V Vialou, M-P Martres, C Chevarin,[...]. Mol Psychiatry 2012
81
14

The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family.
Joao N Dos Santos Pereira, Sina Tadjerpisheh, Manar Abu Abed, Ali R Saadatmand, Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud, Jürgen Brockmöller, Mladen V Tzvetkov. AAPS J 2014
51
23

Discovery of the ergothioneine transporter.
Dirk Gründemann, Stephanie Harlfinger, Stefan Golz, Andreas Geerts, Andreas Lazar, Reinhard Berkels, Norma Jung, Andrea Rubbert, Edgar Schömig. Proc Natl Acad Sci U S A 2005
332
11

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
Yan Shu, Steven A Sheardown, Chaline Brown, Ryan P Owen, Shuzhong Zhang, Richard A Castro, Alexandra G Ianculescu, Lin Yue, Joan C Lo, Esteban G Burchard,[...]. J Clin Invest 2007
615
11

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3.
Martina Hayer-Zillgen, Michael Brüss, Heinz Bönisch. Br J Pharmacol 2002
218
11

Organic cation transporter 3: Keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice.
Nicole L Baganz, Rebecca E Horton, Alfredo S Calderon, W Anthony Owens, Jaclyn L Munn, Lora T Watts, Nina Koldzic-Zivanovic, Nathaniel A Jeske, Wouter Koek, Glenn M Toney,[...]. Proc Natl Acad Sci U S A 2008
121
11

Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2.
I Tamai, R Ohashi, J Nezu, H Yabuuchi, A Oku, M Shimane, Y Sai, A Tsuji. J Biol Chem 1998
548
11

Identification of novel substrates and structure-activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2.
Ramon Hendrickx, Jenny G Johansson, Christina Lohmann, Rose-Marie Jenvert, Anders Blomgren, Lena Börjesson, Lena Gustavsson. J Med Chem 2013
54
20

Profiling solute carrier transporters in the human blood-brain barrier.
E G Geier, E C Chen, A Webb, A C Papp, S W Yee, W Sadee, K M Giacomini. Clin Pharmacol Ther 2013
79
13




Organic cation transporters are determinants of oxaliplatin cytotoxicity.
Shuzhong Zhang, Katherine S Lovejoy, James E Shima, Leah L Lagpacan, Yan Shu, Anna Lapuk, Ying Chen, Takafumi Komori, Joe W Gray, Xin Chen,[...]. Cancer Res 2006
290
10

Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.
Bridget L Morse, Anil Kolur, Loyd R Hudson, Andrew T Hogan, Lisa Hong Chen, Ryan M Brackman, Geri A Sawada, John K Fallon, Philip C Smith, Kathleen M Hillgren. Drug Metab Dispos 2020
15
66

Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3.
Monica Sala-Rabanal, Dan C Li, Gregory R Dake, Harley T Kurata, Mikhail Inyushin, Serguei N Skatchkov, Colin G Nichols. Mol Pharm 2013
54
18


Rat Organic Cation Transporter 1 Contains Three Binding Sites for Substrate 1-Methyl-4-phenylpyridinium per Monomer.
Thorsten Keller, Valentin Gorboulev, Thomas D Mueller, Volker Dötsch, Frank Bernhard, Hermann Koepsell. Mol Pharmacol 2019
20
50

Role of organic cation transporters in drug-drug interaction.
Hermann Koepsell. Expert Opin Drug Metab Toxicol 2015
58
17

Effects of OCT1 polymorphisms on the cellular uptake, plasma concentrations and efficacy of the 5-HT(3) antagonists tropisetron and ondansetron.
M V Tzvetkov, A R Saadatmand, K Bokelmann, I Meineke, R Kaiser, J Brockmöller. Pharmacogenomics J 2012
103
10

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics.
Lorena Pochini, Michele Galluccio, Mariafrancesca Scalise, Lara Console, Cesare Indiveri. SLAS Discov 2019
32
28

Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity.
K K Filipski, R H Mathijssen, T S Mikkelsen, A H Schinkel, A Sparreboom. Clin Pharmacol Ther 2009
249
9

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2.
Jason A Sprowl, Giuliano Ciarimboli, Cynthia S Lancaster, Hugh Giovinazzo, Alice A Gibson, Guoqing Du, Laura J Janke, Guido Cavaletti, Anthony F Shields, Alex Sparreboom. Proc Natl Acad Sci U S A 2013
121
9


Effects of genetic polymorphisms on the OCT1 and OCT2-mediated uptake of ranitidine.
Marleen Julia Meyer, Tina Seitz, Jürgen Brockmöller, Mladen Vassilev Tzvetkov. PLoS One 2017
21
42

The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway.
Mei Cui, Radha Aras, Whitney V Christian, Phillip M Rappold, Mamata Hatwar, Joseph Panza, Vernice Jackson-Lewis, Jonathan A Javitch, Nazzareno Ballatori, Serge Przedborski,[...]. Proc Natl Acad Sci U S A 2009
137
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.