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Nora Pashayan, Steve Morris, Fiona J Gilbert, Paul D P Pharoah. JAMA Oncol 2018
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Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Fredrick R Schumacher, Ali Amin Al Olama, Sonja I Berndt, Sara Benlloch, Mahbubl Ahmed, Edward J Saunders, Tokhir Dadaev, Daniel Leongamornlert, Ezequiel Anokian, Clara Cieza-Borrella,[...]. Nat Genet 2018
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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
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BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.
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Clinical use of current polygenic risk scores may exacerbate health disparities.
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
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Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores.
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
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Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field.
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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
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Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.
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Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.
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Population-standardized genetic risk score: the SNP-based method of choice for inherited risk assessment of prostate cancer.
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Value of genetic testing in the prevention of coronary heart disease events.
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Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting.
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An inherited NBN mutation is associated with poor prognosis prostate cancer.
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Homeobox B13 G84E Mutation and Prostate Cancer Risk.
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Multiple newly identified loci associated with prostate cancer susceptibility.
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Genomic Analysis of Three Metastatic Prostate Cancer Patients with Exceptional Responses to Carboplatin Indicating Different Types of DNA Repair Deficiency.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.