A citation-based method for searching scientific literature

Faezeh Sedighi, Adewale Adegbuyiro, Justin Legleiter. ACS Chem Neurosci 2020
Times Cited: 10







List of co-cited articles
123 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
504
70

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Leslie Michels Thompson, Charity T Aiken, Linda S Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martinez-Vincente, Montserrat Arrasate, Jacqueline Gire O'Rourke, Hasan Khashwji,[...]. J Cell Biol 2009
258
70

Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity.
Charity T Aiken, Joan S Steffan, Cortnie M Guerrero, Hasan Khashwji, Tamas Lukacsovich, Danielle Simmons, Judy M Purcell, Kimia Menhaji, Ya-Zhen Zhu, Kim Green,[...]. J Biol Chem 2009
112
60

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
223
50

Acetylation within the First 17 Residues of Huntingtin Exon 1 Alters Aggregation and Lipid Binding.
Maxmore Chaibva, Sudi Jawahery, Albert W Pilkington, James R Arndt, Olivia Sarver, Stephen Valentine, Silvina Matysiak, Justin Legleiter. Biophys J 2016
36
50

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
237
50

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
312
50

Huntingtin disrupts lipid bilayers in a polyQ-length dependent manner.
Kathleen A Burke, Kaitlin M Hensal, C Samuel Umbaugh, Maxmore Chaibva, Justin Legleiter. Biochim Biophys Acta 2013
46
50



Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
Murali Jayaraman, Ravindra Kodali, Bankanidhi Sahoo, Ashwani K Thakur, Anand Mayasundari, Rakesh Mishra, Cynthia B Peterson, Ronald Wetzel. J Mol Biol 2012
132
50

N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting.
Sean M DeGuire, Francesco S Ruggeri, Mohamed-Bilal Fares, Anass Chiki, Urszula Cendrowska, Giovanni Dietler, Hilal A Lashuel. J Biol Chem 2018
37
40

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease.
Kenneth W Drombosky, Sascha Rode, Ravi Kodali, Tija C Jacob, Michael J Palladino, Ronald Wetzel. Neurobiol Dis 2018
26
40

Mass spectrometric identification of novel lysine acetylation sites in huntingtin.
Xin Cong, Jason M Held, Francesco DeGiacomo, Akilah Bonner, Jan Marie Chen, Birgit Schilling, Gregg A Czerwieniec, Bradford W Gibson, Lisa M Ellerby. Mol Cell Proteomics 2011
25
40

SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation.
Jacqueline Gire O'Rourke, Jaclyn R Gareau, Joseph Ochaba, Wan Song, Tamás Raskó, David Reverter, John Lee, Alex Mas Monteys, Judit Pallos, Lisa Mee,[...]. Cell Rep 2013
67
40

Expanded polyglutamine embedded in the endoplasmic reticulum causes membrane distortion and coincides with Bax insertion.
Masashi Ueda, Shimo Li, Masanori Itoh, Miao-Xing Wang, Miki Hayakawa, Saiful Islam, Tana, Kiyomi Nakagawa, Huayue Chen, Toshiyuki Nakagawa. Biochem Biophys Res Commun 2016
10
40

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
355
40

Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.
Maxmore Chaibva, Xiang Gao, Pranav Jain, Warren A Campbell, Shelli L Frey, Justin Legleiter. ACS Omega 2018
15
40


Huntingtin's N-Terminus Rearrangements in the Presence of Membranes: A Joint Spectroscopic and Computational Perspective.
Geraldine R Levy, Koning Shen, Yulian Gavrilov, Pieter E S Smith, Yaakov Levy, Rebecca Chan, Judith Frydman, Lucio Frydman. ACS Chem Neurosci 2019
11
40

Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates.
Rakesh Mishra, Murali Jayaraman, Bartholomew P Roland, Elizabeth Landrum, Timothy Fullam, Ravindra Kodali, Ashwani K Thakur, Irene Arduini, Ronald Wetzel. J Mol Biol 2012
65
40

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
264
40

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
754
40

The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms.
Nitin K Pandey, J Mario Isas, Anoop Rawat, Rachel V Lee, Jennifer Langen, Priyatama Pandey, Ralf Langen. J Biol Chem 2018
37
40

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N Nukala, Aleksey Kazantsev, J Lawrence Marsh, Patrick G Sullivan, Joan S Steffan, Stefano L Sensi, Leslie Michels Thompson. Hum Mol Genet 2007
194
40

The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin.
Kathleen A Burke, Karlina J Kauffman, C Samuel Umbaugh, Shelli L Frey, Justin Legleiter. J Biol Chem 2013
62
40

Lipid Membranes Influence the Ability of Small Molecules To Inhibit Huntingtin Fibrillization.
Maryssa Beasley, Alyssa R Stonebraker, Iraj Hasan, Kathryn L Kapp, Barry J Liang, Garima Agarwal, Sharon Groover, Faezeh Sedighi, Justin Legleiter. Biochemistry 2019
16
40

Cholesterol Modifies Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.
Xiang Gao, Warren A Campbell, Maxmore Chaibva, Pranav Jain, Ashley E Leslie, Shelli L Frey, Justin Legleiter. Biochemistry 2016
25
40

Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms.
Meixin Tao, Nitin K Pandey, Ryan Barnes, Songi Han, Ralf Langen. Structure 2019
13
40

The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
James R Arndt, Maxmore Chaibva, Justin Legleiter. Biomol Concepts 2015
39
40

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
Joseph Ochaba, Alex Mas Monteys, Jacqueline G O'Rourke, Jack C Reidling, Joan S Steffan, Beverly L Davidson, Leslie M Thompson. Neuron 2016
46
30

The Role of Post-translational Modifications on the Energy Landscape of Huntingtin N-Terminus.
Havva Yalinca, Charlotte Julie Caroline Gehin, Vladimiras Oleinikovas, Hilal A Lashuel, Francesco Luigi Gervasio, Annalisa Pastore. Front Mol Biosci 2019
10
30

Kinase inhibitors modulate huntingtin cell localization and toxicity.
Randy Singh Atwal, Carly R Desmond, Nicholas Caron, Tamara Maiuri, Jianrun Xia, Simonetta Sipione, Ray Truant. Nat Chem Biol 2011
121
30

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
405
30

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
945
30

Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
Anass Chiki, Sean M DeGuire, Francesco S Ruggeri, Domenico Sanfelice, Annalisa Ansaloni, Zhe-Ming Wang, Urszula Cendrowska, Ritwik Burai, Sophie Vieweg, Annalisa Pastore,[...]. Angew Chem Int Ed Engl 2017
38
30

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.
Cristina Cariulo, Lucia Azzollini, Margherita Verani, Paola Martufi, Roberto Boggio, Anass Chiki, Sean M Deguire, Marta Cherubini, Silvia Gines, J Lawrence Marsh,[...]. Proc Natl Acad Sci U S A 2017
30
30

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
30


Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells.
Laura Pieri, Karine Madiona, Luc Bousset, Ronald Melki. Biophys J 2012
172
30

Probing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulations.
Sébastien Côté, Vincent Binette, Evgeniy S Salnikov, Burkhard Bechinger, Normand Mousseau. Biophys J 2015
16
30

Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.
Kuan-Yu Liu, Yu-Chiau Shyu, Brett A Barbaro, Yuan-Ta Lin, Yijuang Chern, Leslie Michels Thompson, Che-Kun James Shen, J Lawrence Marsh. Hum Mol Genet 2015
50
30

Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors.
Yujin E Kim, Fabian Hosp, Frédéric Frottin, Hui Ge, Matthias Mann, Manajit Hayer-Hartl, F Ulrich Hartl. Mol Cell 2016
105
30

Post-aggregation oxidation of mutant huntingtin controls the interactions between aggregates.
Yasushi Mitomi, Takao Nomura, Masaru Kurosawa, Nobuyuki Nukina, Yoshiaki Furukawa. J Biol Chem 2012
17
30

Membrane interactions of the amphipathic amino terminus of huntingtin.
Matthias Michalek, Evgeniy S Salnikov, Sebastiaan Werten, Burkhard Bechinger. Biochemistry 2013
64
30

Curvature enhances binding and aggregation of huntingtin at lipid membranes.
Maxmore Chaibva, Kathleen A Burke, Justin Legleiter. Biochemistry 2014
34
30

Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.
Adewale Adegbuyiro, Faezeh Sedighi, Albert W Pilkington, Sharon Groover, Justin Legleiter. Biochemistry 2017
70
30

Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy.
Kathleen A Burke, Jordan Godbey, Justin Legleiter. Methods 2011
42
30

Amphipathic helices and membrane curvature.
Guillaume Drin, Bruno Antonny. FEBS Lett 2010
352
30

In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
Felix J B Bäuerlein, Itika Saha, Archana Mishra, Maria Kalemanov, Antonio Martínez-Sánchez, Rüdiger Klein, Irina Dudanova, Mark S Hipp, F Ulrich Hartl, Wolfgang Baumeister,[...]. Cell 2017
151
30


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.