Marco Jost, Daniel A Santos, Reuben A Saunders, Max A Horlbeck, John S Hawkins, Sonia M Scaria, Thomas M Norman, Jeffrey A Hussmann, Christina R Liem, Carol A Gross, Jonathan S Weissman. Nat Biotechnol 2020
Times Cited: 47
Times Cited: 47
Times Cited
Times Co-cited
Similarity
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
Luke A Gilbert, Matthew H Larson, Leonardo Morsut, Zairan Liu, Gloria A Brar, Sandra E Torres, Noam Stern-Ginossar, Onn Brandman, Evan H Whitehead, Jennifer A Doudna,[...]. Cell 2013
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.
Jason M Peters, Alexandre Colavin, Handuo Shi, Tomasz L Czarny, Matthew H Larson, Spencer Wong, John S Hawkins, Candy H S Lu, Byoung-Mo Koo, Elizabeth Marta,[...]. Cell 2016
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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.
Silvana Konermann, Mark D Brigham, Alexandro E Trevino, Julia Joung, Omar O Abudayyeh, Clea Barcena, Patrick D Hsu, Naomi Habib, Jonathan S Gootenberg, Hiroshi Nishimasu,[...]. Nature 2015
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Highly efficient Cas9-mediated transcriptional programming.
Alejandro Chavez, Jonathan Scheiman, Suhani Vora, Benjamin W Pruitt, Marcelle Tuttle, Eswar P R Iyer, Shuailiang Lin, Samira Kiani, Christopher D Guzman, Daniel J Wiegand,[...]. Nat Methods 2015
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Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors.
François Rousset, Lun Cui, Elise Siouve, Christophe Becavin, Florence Depardieu, David Bikard. PLoS Genet 2018
François Rousset, Lun Cui, Elise Siouve, Christophe Becavin, Florence Depardieu, David Bikard. PLoS Genet 2018
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High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.
Evan A Boyle, Johan O L Andreasson, Lauren M Chircus, Samuel H Sternberg, Michelle J Wu, Chantal K Guegler, Jennifer A Doudna, William J Greenleaf. Proc Natl Acad Sci U S A 2017
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
David Bikard, Wenyan Jiang, Poulami Samai, Ann Hochschild, Feng Zhang, Luciano A Marraffini. Nucleic Acids Res 2013
David Bikard, Wenyan Jiang, Poulami Samai, Ann Hochschild, Feng Zhang, Luciano A Marraffini. Nucleic Acids Res 2013
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Johnny H Hu, Shannon M Miller, Maarten H Geurts, Weixin Tang, Liwei Chen, Ning Sun, Christina M Zeina, Xue Gao, Holly A Rees, Zhi Lin,[...]. Nature 2018
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DNA targeting specificity of RNA-guided Cas9 nucleases.
Patrick D Hsu, David A Scott, Joshua A Weinstein, F Ann Ran, Silvana Konermann, Vineeta Agarwala, Yinqing Li, Eli J Fine, Xuebing Wu, Ophir Shalem,[...]. Nat Biotechnol 2013
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A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9.
Lun Cui, Antoine Vigouroux, François Rousset, Hugo Varet, Varun Khanna, David Bikard. Nat Commun 2018
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Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance.
Tianmin Wang, Changge Guan, Jiahui Guo, Bing Liu, Yinan Wu, Zhen Xie, Chong Zhang, Xin-Hui Xing. Nat Commun 2018
Tianmin Wang, Changge Guan, Jiahui Guo, Bing Liu, Yinan Wu, Zhen Xie, Chong Zhang, Xin-Hui Xing. Nat Commun 2018
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Search-and-replace genome editing without double-strand breaks or donor DNA.
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Multiplex genome engineering using CRISPR/Cas systems.
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CRISPR interference (CRISPRi) for sequence-specific control of gene expression.
Matthew H Larson, Luke A Gilbert, Xiaowo Wang, Wendell A Lim, Jonathan S Weissman, Lei S Qi. Nat Protoc 2013
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Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis.
John S Hawkins, Melanie R Silvis, Byoung-Mo Koo, Jason M Peters, Hendrik Osadnik, Marco Jost, Cameron C Hearne, Jonathan S Weissman, Horia Todor, Carol A Gross. Cell Syst 2020
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Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes.
Antoine Vigouroux, Enno Oldewurtel, Lun Cui, David Bikard, Sven van Teeffelen. Mol Syst Biol 2018
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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
Samuel H Sternberg, Sy Redding, Martin Jinek, Eric C Greene, Jennifer A Doudna. Nature 2014
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.
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Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi.
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Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
Jeremy M Rock, Forrest F Hopkins, Alejandro Chavez, Marieme Diallo, Michael R Chase, Elias R Gerrick, Justin R Pritchard, George M Church, Eric J Rubin, Christopher M Sassetti,[...]. Nat Microbiol 2017
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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
John G Doench, Nicolo Fusi, Meagan Sullender, Mudra Hegde, Emma W Vaimberg, Katherine F Donovan, Ian Smith, Zuzana Tothova, Craig Wilen, Robert Orchard,[...]. Nat Biotechnol 2016
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Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation.
Max A Horlbeck, Luke A Gilbert, Jacqueline E Villalta, Britt Adamson, Ryan A Pak, Yuwen Chen, Alexander P Fields, Chong Yon Park, Jacob E Corn, Martin Kampmann,[...]. Elife 2016
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On-target activity predictions enable improved CRISPR-dCas9 screens in bacteria.
Alicia Calvo-Villamañán, Jérome Wong Ng, Rémi Planel, Hervé Ménager, Arthur Chen, Lun Cui, David Bikard. Nucleic Acids Res 2020
Alicia Calvo-Villamañán, Jérome Wong Ng, Rémi Planel, Hervé Ménager, Arthur Chen, Lun Cui, David Bikard. Nucleic Acids Res 2020
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Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors.
Y Esther Tak, Benjamin P Kleinstiver, James K Nuñez, Jonathan Y Hsu, Joy E Horng, Jingyi Gong, Jonathan S Weissman, J Keith Joung. Nat Methods 2017
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Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness.
Leeat Keren, Jean Hausser, Maya Lotan-Pompan, Ilya Vainberg Slutskin, Hadas Alisar, Sivan Kaminski, Adina Weinberger, Uri Alon, Ron Milo, Eran Segal. Cell 2016
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High-throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae.
Xue Liu, Clement Gallay, Morten Kjos, Arnau Domenech, Jelle Slager, Sebastiaan P van Kessel, Kèvin Knoops, Robin A Sorg, Jing-Ren Zhang, Jan-Willem Veening. Mol Syst Biol 2017
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Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.
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Simultaneous repression of multiple bacterial genes using nonrepetitive extra-long sgRNA arrays.
Alexander C Reis, Sean M Halper, Grace E Vezeau, Daniel P Cetnar, Ayaan Hossain, Phillip R Clauer, Howard M Salis. Nat Biotechnol 2019
Alexander C Reis, Sean M Halper, Grace E Vezeau, Daniel P Cetnar, Ayaan Hossain, Phillip R Clauer, Howard M Salis. Nat Biotechnol 2019
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
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Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Fiona M Behan, Francesco Iorio, Gabriele Picco, Emanuel Gonçalves, Charlotte M Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli,[...]. Nature 2019
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing.
Angelo Amabile, Alessandro Migliara, Paola Capasso, Mauro Biffi, Davide Cittaro, Luigi Naldini, Angelo Lombardo. Cell 2016
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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach. Nat Biotechnol 2015
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An enhanced CRISPR repressor for targeted mammalian gene regulation.
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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.
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Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.
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RNA-guided editing of bacterial genomes using CRISPR-Cas systems.
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Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.
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Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.
Kyuho Han, Edwin E Jeng, Gaelen T Hess, David W Morgens, Amy Li, Michael C Bassik. Nat Biotechnol 2017
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RNA editing with CRISPR-Cas13.
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Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs.
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Editing DNA Methylation in the Mammalian Genome.
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Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping.
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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.