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List of co-cited articles
94 articles co-cited >1



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  Times     Co-cited
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Huntingtin Lowering Strategies for Disease Modification in Huntington's Disease.
Sarah J Tabrizi, Rhia Ghosh, Blair R Leavitt. Neuron 2019
88
46

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
560
30

AAV5-miHTT Gene Therapy Demonstrates Sustained Huntingtin Lowering and Functional Improvement in Huntington Disease Mouse Models.
Elisabeth A Spronck, Cynthia C Brouwers, Astrid Vallès, Martin de Haan, Harald Petry, Sander J van Deventer, Pavlina Konstantinova, Melvin M Evers. Mol Ther Methods Clin Dev 2019
29
30

AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.
J Miniarikova, V Zimmer, R Martier, C C Brouwers, C Pythoud, K Richetin, M Rey, J Lubelski, M M Evers, S J van Deventer,[...]. Gene Ther 2017
46
30

AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington's Disease Minipig Model.
Melvin M Evers, Jana Miniarikova, Stefan Juhas, Astrid Vallès, Bozena Bohuslavova, Jana Juhasova, Helena Kupcova Skalnikova, Petr Vodicka, Ivona Valekova, Cynthia Brouwers,[...]. Mol Ther 2018
75
30

Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
304
30


Therapeutic Advances for Huntington's Disease.
Ashok Kumar, Vijay Kumar, Kritanjali Singh, Sukesh Kumar, You-Sam Kim, Yun-Mi Lee, Jong-Joo Kim. Brain Sci 2020
28
30

Therapies targeting DNA and RNA in Huntington's disease.
Edward J Wild, Sarah J Tabrizi. Lancet Neurol 2017
146
30

Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities.
Sarah J Tabrizi, Michael D Flower, Christopher A Ross, Edward J Wild. Nat Rev Neurol 2020
72
30

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
Ryan L Boudreau, Jodi L McBride, Inês Martins, Shihao Shen, Yi Xing, Barrie J Carter, Beverly L Davidson. Mol Ther 2009
244
23

RNAi mechanisms in Huntington's disease therapy: siRNA versus shRNA.
Sebastian Aguiar, Bram van der Gaag, Francesco Albert Bosco Cortese. Transl Neurodegener 2017
29
23

Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Edith L Pfister, Natalie DiNardo, Erica Mondo, Florie Borel, Faith Conroy, Cara Fraser, Gwladys Gernoux, Xin Han, Danjing Hu, Emily Johnson,[...]. Hum Gene Ther 2018
51
23

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.
Bryan Zeitler, Steven Froelich, Kimberly Marlen, David A Shivak, Qi Yu, Davis Li, Jocelynn R Pearl, Jeffrey C Miller, Lei Zhang, David E Paschon,[...]. Nat Med 2019
70
23

CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.
Su Yang, Renbao Chang, Huiming Yang, Ting Zhao, Yan Hong, Ha Eun Kong, Xiaobo Sun, Zhaohui Qin, Peng Jin, Shihua Li,[...]. J Clin Invest 2017
172
23

Recent advances in the therapeutic development for Huntington disease.
Tiago A Mestre. Parkinsonism Relat Disord 2019
8
37

Laquinimod treatment in the R6/2 mouse model.
Gisa Ellrichmann, Alina Blusch, Oluwaseun Fatoba, Janine Brunner, Christiane Reick, Liat Hayardeny, Michael Hayden, Dominik Sehr, Konstanze F Winklhofer, Carsten Saft,[...]. Sci Rep 2017
24
23

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
23

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
405
23

The Prevalence of Huntington's Disease.
Michael D Rawlins, Nancy S Wexler, Alice R Wexler, Sarah J Tabrizi, Ian Douglas, Stephen J W Evans, Liam Smeeth. Neuroepidemiology 2016
137
23


Huntington's disease: a clinical review.
P McColgan, S J Tabrizi. Eur J Neurol 2018
321
23

Huntington disease: pathogenesis and treatment.
Praveen Dayalu, Roger L Albin. Neurol Clin 2015
100
23

Emerging Issues in AAV-Mediated In Vivo Gene Therapy.
Pasqualina Colella, Giuseppe Ronzitti, Federico Mingozzi. Mol Ther Methods Clin Dev 2017
359
15

Stem cells in animal models of Huntington disease: A systematic review.
Gabriela Delevati Colpo, Erin Furr Stimming, Antonio Lucio Teixeira. Mol Cell Neurosci 2019
12
16

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery.
Jung Soo Suk, Qingguo Xu, Namho Kim, Justin Hanes, Laura M Ensign. Adv Drug Deliv Rev 2016
15

Current status of non-viral gene therapy for CNS disorders.
Rahul Dev Jayant, Daniela Sosa, Ajeet Kaushik, Venkata Atluri, Arti Vashist, Asahi Tomitaka, Madhavan Nair. Expert Opin Drug Deliv 2016
47
15

Silencing mutant huntingtin by adeno-associated virus-mediated RNA interference ameliorates disease manifestations in the YAC128 mouse model of Huntington's disease.
Lisa M Stanek, Sergio P Sardi, Bryan Mastis, Amy R Richards, Christopher M Treleaven, Tatyana Taksir, Kuma Misra, Seng H Cheng, Lamya S Shihabuddin. Hum Gene Ther 2014
108
15

Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease.
Jodi L McBride, Mark R Pitzer, Ryan L Boudreau, Brett Dufour, Theodore Hobbs, Sergio R Ojeda, Beverly L Davidson. Mol Ther 2011
162
15

High-capacity adenoviral vector-mediated reduction of huntingtin aggregate load in vitro and in vivo.
Bin Huang, Johannes Schiefer, Christian Sass, G Bernhard Landwehrmeyer, Christoph M Kosinski, Stefan Kochanek. Hum Gene Ther 2007
42
15

Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Francesca Cicchetti, Steve Lacroix, Giulia Cisbani, Nicolas Vallières, Martine Saint-Pierre, Isabelle St-Amour, Ranna Tolouei, Jeremy N Skepper, Robert A Hauser, Diego Mantovani,[...]. Ann Neurol 2014
121
15

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.
Nicolas Merienne, Gabriel Vachey, Lucie de Longprez, Cécile Meunier, Virginie Zimmer, Guillaume Perriard, Mathieu Canales, Amandine Mathias, Lucas Herrgott, Tim Beltraminelli,[...]. Cell Rep 2017
65
15

Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice.
Carmen Agustín-Pavón, Michal Mielcarek, Mireia Garriga-Canut, Mark Isalan. Mol Neurodegener 2016
30
15

Emerging therapies in Huntington's disease.
Hassaan Bashir. Expert Rev Neurother 2019
9
22

Normal huntingtin function: an alternative approach to Huntington's disease.
Elena Cattaneo, Chiara Zuccato, Marzia Tartari. Nat Rev Neurosci 2005
450
15

Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's Disease.
Rajeev K Chaudhary, Kinjal A Patel, Milan K Patel, Radha H Joshi, Ipsita Roy. Mol Ther 2015
23
15

Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA.
Yu-Lai Wang, Wanzhao Liu, Etsuko Wada, Miho Murata, Keiji Wada, Ichiro Kanazawa. Neurosci Res 2005
131
15

Aptamers as targeted therapeutics: current potential and challenges.
Jiehua Zhou, John Rossi. Nat Rev Drug Discov 2017
697
15

Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington's disease.
Arlene I Ramsingh, Kevin Manley, Yinghui Rong, Andrew Reilly, Anne Messer. Hum Mol Genet 2015
14
15

Therapeutic approaches to Huntington disease: from the bench to the clinic.
Nicholas S Caron, E Ray Dorsey, Michael R Hayden. Nat Rev Drug Discov 2018
73
15


Therapeutic Antisense Targeting of Huntingtin.
Anne V Smith, Sarah J Tabrizi. DNA Cell Biol 2020
11
18

Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.
Amber L Southwell, Sonia Franciosi, Erika B Villanueva, Yuanyun Xie, Laurie A Winter, Janaki Veeraraghavan, Alan Jonason, Boguslaw Felczak, Weining Zhang, Vlad Kovalik,[...]. Neurobiol Dis 2015
56
15

Nucleic Acid Therapeutics in Huntington's Disease.
Kuljit Singh, Ipsita Roy. Recent Pat Biotechnol 2019
3
66

Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.
Allison M Keeler, Ellen Sapp, Kathryn Chase, Emily Sottosanti, Eric Danielson, Edith Pfister, Lorelei Stoica, Marian DiFiglia, Neil Aronin, Miguel Sena-Esteves. J Huntingtons Dis 2016
20
15

Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.
Baehyun Shin, Roy Jung, Hyejin Oh, Gwen E Owens, Hyeongseok Lee, Seung Kwak, Ramee Lee, Susan L Cotman, Jong-Min Lee, Marcy E MacDonald,[...]. Mol Ther Nucleic Acids 2018
8
25

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Holly B Kordasiewicz, Lisa M Stanek, Edward V Wancewicz, Curt Mazur, Melissa M McAlonis, Kimberly A Pytel, Jonathan W Artates, Andreas Weiss, Seng H Cheng, Lamya S Shihabuddin,[...]. Neuron 2012
485
15

Immunotherapies in Huntington's disease and α-Synucleinopathies.
Oluwaseun Fatoba, Yosuke Ohtake, Takahide Itokazu, Toshihide Yamashita. Front Immunol 2020
7
28

Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease.
Marta Garcia-Miralles, Nur Amirah Binte Mohammad Yusof, Jing Ying Tan, Carola I Radulescu, Harwin Sidik, Liang Juin Tan, Haim Belinson, Neta Zach, Michael R Hayden, Mahmoud A Pouladi. Mol Neurobiol 2019
19
15

Designing aptamers which respond to intracellular oxidative stress and inhibit aggregation of mutant huntingtin.
Kinjal A Patel, Thulasi Kolluri, Swati Jain, Ipsita Roy. Free Radic Biol Med 2018
5
40


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.