Amir Sharabi, George C Tsokos. Nat Rev Rheumatol 2020
Times Cited: 36
Times Cited: 36
Times Cited
Times Co-cited
Similarity
A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate.
Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung,[...]. Nat Med 2019
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Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
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New insights into the immunopathogenesis of systemic lupus erythematosus.
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
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Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
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Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
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N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
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Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.
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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
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Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos. Arthritis Rheumatol 2019
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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
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HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
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Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.
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Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.
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A guide to immunometabolism for immunologists.
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Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study.
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Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells.
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The multiple pathways to autoimmunity.
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A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.
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Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
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The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.
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Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.
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Precision DNA demethylation ameliorates disease in lupus-prone mice.
Hao Li, Maria G Tsokos, Sean Bickerton, Amir Sharabi, Yi Li, Vaishali R Moulton, Philip Kong, Tarek M Fahmy, George C Tsokos. JCI Insight 2018
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CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease.
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Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.
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T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.
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The immune cell landscape in kidneys of patients with lupus nephritis.
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Circulating follicular helper-like T cells in systemic lupus erythematosus: association with disease activity.
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Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective.
Vaishali R Moulton, Abel Suarez-Fueyo, Esra Meidan, Hao Li, Masayuki Mizui, George C Tsokos. Trends Mol Med 2017
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Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.
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Kidney tissue hypoxia dictates T cell-mediated injury in murine lupus nephritis.
Ping-Min Chen, Parker C Wilson, Justin A Shyer, Margaret Veselits, Holly R Steach, Can Cui, Gilbert Moeckel, Marcus R Clark, Joe Craft. Sci Transl Med 2020
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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, George C Tsokos. Proc Natl Acad Sci U S A 2018
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Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
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8
Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation.
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ICER is requisite for Th17 differentiation.
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Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus.
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Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.