Amir Sharabi, George C Tsokos. Nat Rev Rheumatol 2020
Times Cited: 63
Times Cited: 63
Times Cited
Times Co-cited
Similarity
New insights into the immunopathogenesis of systemic lupus erythematosus.
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
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Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
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Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
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HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
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Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.
Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton. Front Immunol 2018
Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton. Front Immunol 2018
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A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate.
Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung,[...]. Nat Med 2019
Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung,[...]. Nat Med 2019
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A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
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N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
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Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
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De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
Luciana Berod, Christin Friedrich, Amrita Nandan, Jenny Freitag, Stefanie Hagemann, Kirsten Harmrolfs, Aline Sandouk, Christina Hesse, Carla N Castro, Heike Bähre,[...]. Nat Med 2014
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Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos. Arthritis Rheumatol 2019
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos. Arthritis Rheumatol 2019
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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Valerie A Gerriets, Rigel J Kishton, Amanda G Nichols, Andrew N Macintyre, Makoto Inoue, Olga Ilkayeva, Peter S Winter, Xiaojing Liu, Bhavana Priyadharshini, Marta E Slawinska,[...]. J Clin Invest 2015
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Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, George C Tsokos. Proc Natl Acad Sci U S A 2018
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
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Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
M C Hochberg. Arthritis Rheum 1997
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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
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IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus.
Hong Dai, Fan He, George C Tsokos, Vasileios C Kyttaris. J Immunol 2017
Hong Dai, Fan He, George C Tsokos, Vasileios C Kyttaris. J Immunol 2017
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Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells.
Hao Li, Iannis E Adamopoulos, Vaishali R Moulton, Isaac E Stillman, Zach Herbert, James J Moon, Amir Sharabi, Suzanne Krishfield, Maria G Tsokos, George C Tsokos. Nat Commun 2020
Hao Li, Iannis E Adamopoulos, Vaishali R Moulton, Isaac E Stillman, Zach Herbert, James J Moon, Amir Sharabi, Suzanne Krishfield, Maria G Tsokos, George C Tsokos. Nat Commun 2020
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Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
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Precision DNA demethylation ameliorates disease in lupus-prone mice.
Hao Li, Maria G Tsokos, Sean Bickerton, Amir Sharabi, Yi Li, Vaishali R Moulton, Philip Kong, Tarek M Fahmy, George C Tsokos. JCI Insight 2018
Hao Li, Maria G Tsokos, Sean Bickerton, Amir Sharabi, Yi Li, Vaishali R Moulton, Philip Kong, Tarek M Fahmy, George C Tsokos. JCI Insight 2018
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CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease.
Kayaho Maeda, Kotaro Otomo, Nobuya Yoshida, Mones S Abu-Asab, Kunihiro Ichinose, Tomoya Nishino, Michihito Kono, Andrew Ferretti, Rhea Bhargava, Shoichi Maruyama,[...]. J Clin Invest 2018
Kayaho Maeda, Kotaro Otomo, Nobuya Yoshida, Mones S Abu-Asab, Kunihiro Ichinose, Tomoya Nishino, Michihito Kono, Andrew Ferretti, Rhea Bhargava, Shoichi Maruyama,[...]. J Clin Invest 2018
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Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.
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Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.
Hiroshi Kato, Andras Perl. J Immunol 2014
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Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P Croker, Laurence Morel. J Immunol 2016
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P Croker, Laurence Morel. J Immunol 2016
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Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
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Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
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CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance.
Tomohiro Koga, Christian M Hedrich, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, Thomas Rauen, José C Crispín, George C Tsokos. J Clin Invest 2014
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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
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Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
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Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study.
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Metabolic abnormalities and oxidative stress in lupus.
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Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.
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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
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Metabolic control of T cells in autoimmunity.
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T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus.
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Metabolic regulation of T lymphocytes.
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Management strategies and future directions for systemic lupus erythematosus in adults.
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The multiple pathways to autoimmunity.
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The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.
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Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.
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Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.
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Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.
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Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
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Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.