Amir Sharabi, George C Tsokos. Nat Rev Rheumatol 2020
Times Cited: 63
Times Cited: 63
Times Cited
Times Co-cited
Similarity
New insights into the immunopathogenesis of systemic lupus erythematosus.
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
George C Tsokos, Mindy S Lo, Patricia Costa Reis, Kathleen E Sullivan. Nat Rev Rheumatol 2016
19
Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
17
Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
15
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
14
Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.
Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton. Front Immunol 2018
Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton. Front Immunol 2018
14
A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate.
Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung,[...]. Nat Med 2019
Simone Caielli, Diogo Troggian Veiga, Preetha Balasubramanian, Shruti Athale, Bojana Domic, Elise Murat, Romain Banchereau, Zhaohui Xu, Manjari Chandra, Cheng-Han Chung,[...]. Nat Med 2019
12
12
A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
12
N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
12
Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
11
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.
Luciana Berod, Christin Friedrich, Amrita Nandan, Jenny Freitag, Stefanie Hagemann, Kirsten Harmrolfs, Aline Sandouk, Christina Hesse, Carla N Castro, Heike Bähre,[...]. Nat Med 2014
Luciana Berod, Christin Friedrich, Amrita Nandan, Jenny Freitag, Stefanie Hagemann, Kirsten Harmrolfs, Aline Sandouk, Christina Hesse, Carla N Castro, Heike Bähre,[...]. Nat Med 2014
11
Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos. Arthritis Rheumatol 2019
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C Kyttaris, George C Tsokos. Arthritis Rheumatol 2019
18
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Valerie A Gerriets, Rigel J Kishton, Amanda G Nichols, Andrew N Macintyre, Makoto Inoue, Olga Ilkayeva, Peter S Winter, Xiaojing Liu, Bhavana Priyadharshini, Marta E Slawinska,[...]. J Clin Invest 2015
Valerie A Gerriets, Rigel J Kishton, Amanda G Nichols, Andrew N Macintyre, Makoto Inoue, Olga Ilkayeva, Peter S Winter, Xiaojing Liu, Bhavana Priyadharshini, Marta E Slawinska,[...]. J Clin Invest 2015
9
Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells.
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, George C Tsokos. Proc Natl Acad Sci U S A 2018
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, George C Tsokos. Proc Natl Acad Sci U S A 2018
13
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
Alessia Angelin, Luis Gil-de-Gómez, Satinder Dahiya, Jing Jiao, Lili Guo, Matthew H Levine, Zhonglin Wang, William J Quinn, Piotr K Kopinski, Liqing Wang,[...]. Cell Metab 2017
Alessia Angelin, Luis Gil-de-Gómez, Satinder Dahiya, Jing Jiao, Lili Guo, Matthew H Levine, Zhonglin Wang, William J Quinn, Piotr K Kopinski, Liqing Wang,[...]. Cell Metab 2017
9
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus.
M C Hochberg. Arthritis Rheum 1997
M C Hochberg. Arthritis Rheum 1997
9
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
9
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
9
IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus.
Hong Dai, Fan He, George C Tsokos, Vasileios C Kyttaris. J Immunol 2017
Hong Dai, Fan He, George C Tsokos, Vasileios C Kyttaris. J Immunol 2017
12
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells.
Hao Li, Iannis E Adamopoulos, Vaishali R Moulton, Isaac E Stillman, Zach Herbert, James J Moon, Amir Sharabi, Suzanne Krishfield, Maria G Tsokos, George C Tsokos. Nat Commun 2020
Hao Li, Iannis E Adamopoulos, Vaishali R Moulton, Isaac E Stillman, Zach Herbert, James J Moon, Amir Sharabi, Suzanne Krishfield, Maria G Tsokos, George C Tsokos. Nat Commun 2020
30
Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus.
Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Jun Deng, Yuebo Jin, Yuzhou Gan, Xin Hu, Rulin Jia,[...]. Nat Med 2016
Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Jun Deng, Yuebo Jin, Yuzhou Gan, Xin Hu, Rulin Jia,[...]. Nat Med 2016
7
Precision DNA demethylation ameliorates disease in lupus-prone mice.
Hao Li, Maria G Tsokos, Sean Bickerton, Amir Sharabi, Yi Li, Vaishali R Moulton, Philip Kong, Tarek M Fahmy, George C Tsokos. JCI Insight 2018
Hao Li, Maria G Tsokos, Sean Bickerton, Amir Sharabi, Yi Li, Vaishali R Moulton, Philip Kong, Tarek M Fahmy, George C Tsokos. JCI Insight 2018
16
CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease.
Kayaho Maeda, Kotaro Otomo, Nobuya Yoshida, Mones S Abu-Asab, Kunihiro Ichinose, Tomoya Nishino, Michihito Kono, Andrew Ferretti, Rhea Bhargava, Shoichi Maruyama,[...]. J Clin Invest 2018
Kayaho Maeda, Kotaro Otomo, Nobuya Yoshida, Mones S Abu-Asab, Kunihiro Ichinose, Tomoya Nishino, Michihito Kono, Andrew Ferretti, Rhea Bhargava, Shoichi Maruyama,[...]. J Clin Invest 2018
11
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.
Tao Xu, Kelly M Stewart, Xiaohu Wang, Kai Liu, Min Xie, Jae Kyu Ryu, Ke Li, Tianhua Ma, Haixia Wang, Lu Ni,[...]. Nature 2017
Tao Xu, Kelly M Stewart, Xiaohu Wang, Kai Liu, Min Xie, Jae Kyu Ryu, Ke Li, Tianhua Ma, Haixia Wang, Lu Ni,[...]. Nature 2017
7
Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.
Hiroshi Kato, Andras Perl. J Immunol 2014
Hiroshi Kato, Andras Perl. J Immunol 2014
7
Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P Croker, Laurence Morel. J Immunol 2016
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P Croker, Laurence Morel. J Immunol 2016
7
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
7
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
Valerie A Gerriets, Rigel J Kishton, Marc O Johnson, Sivan Cohen, Peter J Siska, Amanda G Nichols, Marc O Warmoes, Aguirre A de Cubas, Nancie J MacIver, Jason W Locasale,[...]. Nat Immunol 2016
7
CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance.
Tomohiro Koga, Christian M Hedrich, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, Thomas Rauen, José C Crispín, George C Tsokos. J Clin Invest 2014
Tomohiro Koga, Christian M Hedrich, Masayuki Mizui, Nobuya Yoshida, Kotaro Otomo, Linda A Lieberman, Thomas Rauen, José C Crispín, George C Tsokos. J Clin Invest 2014
7
mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
Hu Zeng, Kai Yang, Caryn Cloer, Geoffrey Neale, Peter Vogel, Hongbo Chi. Nature 2013
7
Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
7
Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study.
Ronald F van Vollenhoven, Bevra H Hahn, George C Tsokos, Carrie L Wagner, Peter Lipsky, Zahi Touma, Victoria P Werth, Robert M Gordon, Bei Zhou, Benjamin Hsu,[...]. Lancet 2018
Ronald F van Vollenhoven, Bevra H Hahn, George C Tsokos, Carrie L Wagner, Peter Lipsky, Zahi Touma, Victoria P Werth, Robert M Gordon, Bei Zhou, Benjamin Hsu,[...]. Lancet 2018
7
Metabolic abnormalities and oxidative stress in lupus.
Yaima L Lightfoot, Luz P Blanco, Mariana J Kaplan. Curr Opin Rheumatol 2017
Yaima L Lightfoot, Luz P Blanco, Mariana J Kaplan. Curr Opin Rheumatol 2017
11
Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.
Peter Gergely, Craig Grossman, Brian Niland, Ferenc Puskas, Hom Neupane, Fatme Allam, Katalin Banki, Paul E Phillips, Andras Perl. Arthritis Rheum 2002
Peter Gergely, Craig Grossman, Brian Niland, Ferenc Puskas, Hom Neupane, Fatme Allam, Katalin Banki, Paul E Phillips, Andras Perl. Arthritis Rheum 2002
7
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
7
Metabolic control of T cells in autoimmunity.
Michihito Kono, Nobuya Yoshida, George C Tsokos. Curr Opin Rheumatol 2020
Michihito Kono, Nobuya Yoshida, George C Tsokos. Curr Opin Rheumatol 2020
62
T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus.
Juan Shan, Hong Jin, Yan Xu. Front Immunol 2020
Juan Shan, Hong Jin, Yan Xu. Front Immunol 2020
17
Metabolic regulation of T lymphocytes.
Nancie J MacIver, Ryan D Michalek, Jeffrey C Rathmell. Annu Rev Immunol 2013
Nancie J MacIver, Ryan D Michalek, Jeffrey C Rathmell. Annu Rev Immunol 2013
7
Management strategies and future directions for systemic lupus erythematosus in adults.
Laura Durcan, Tom O'Dwyer, Michelle Petri. Lancet 2019
Laura Durcan, Tom O'Dwyer, Michelle Petri. Lancet 2019
6
The multiple pathways to autoimmunity.
Argyrios N Theofilopoulos, Dwight H Kono, Roberto Baccala. Nat Immunol 2017
Argyrios N Theofilopoulos, Dwight H Kono, Roberto Baccala. Nat Immunol 2017
6
The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections.
Eri Katsuyama, Abel Suarez-Fueyo, Sean J Bradley, Masayuki Mizui, Ana V Marin, Lama Mulki, Suzanne Krishfield, Fabio Malavasi, Joon Yoon, Shannan J Ho Sui,[...]. Cell Rep 2020
Eri Katsuyama, Abel Suarez-Fueyo, Sean J Bradley, Masayuki Mizui, Ana V Marin, Lama Mulki, Suzanne Krishfield, Fabio Malavasi, Joon Yoon, Shannan J Ho Sui,[...]. Cell Rep 2020
7
Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.
Vladimir M Liarski, Natalya Kaverina, Anthony Chang, Daniel Brandt, Denisse Yanez, Lauren Talasnik, Gianluca Carlesso, Ronald Herbst, Tammy O Utset, Christine Labno,[...]. Sci Transl Med 2014
Vladimir M Liarski, Natalya Kaverina, Anthony Chang, Daniel Brandt, Denisse Yanez, Lauren Talasnik, Gianluca Carlesso, Ronald Herbst, Tammy O Utset, Christine Labno,[...]. Sci Transl Med 2014
6
Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.
Romain Banchereau, Seunghee Hong, Brandi Cantarel, Nicole Baldwin, Jeanine Baisch, Michelle Edens, Alma-Martina Cepika, Peter Acs, Jacob Turner, Esperanza Anguiano,[...]. Cell 2016
Romain Banchereau, Seunghee Hong, Brandi Cantarel, Nicole Baldwin, Jeanine Baisch, Michelle Edens, Alma-Martina Cepika, Peter Acs, Jacob Turner, Esperanza Anguiano,[...]. Cell 2016
6
Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.
Gina S Garcia-Romo, Simone Caielli, Barbara Vega, John Connolly, Florence Allantaz, Zhaohui Xu, Marilynn Punaro, Jeanine Baisch, Cristiana Guiducci, Robert L Coffman,[...]. Sci Transl Med 2011
Gina S Garcia-Romo, Simone Caielli, Barbara Vega, John Connolly, Florence Allantaz, Zhaohui Xu, Marilynn Punaro, Jeanine Baisch, Cristiana Guiducci, Robert L Coffman,[...]. Sci Transl Med 2011
6
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.
Scott A Jenks, Kevin S Cashman, Esther Zumaquero, Urko M Marigorta, Aakash V Patel, Xiaoqian Wang, Deepak Tomar, Matthew C Woodruff, Zoe Simon, Regina Bugrovsky,[...]. Immunity 2018
Scott A Jenks, Kevin S Cashman, Esther Zumaquero, Urko M Marigorta, Aakash V Patel, Xiaoqian Wang, Deepak Tomar, Matthew C Woodruff, Zoe Simon, Regina Bugrovsky,[...]. Immunity 2018
6
Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients.
Georgia McDonald, Shantal Deepak, Laura Miguel, Cleo J Hall, David A Isenberg, Anthony I Magee, Terry Butters, Elizabeth C Jury. J Clin Invest 2014
Georgia McDonald, Shantal Deepak, Laura Miguel, Cleo J Hall, David A Isenberg, Anthony I Magee, Terry Butters, Elizabeth C Jury. J Clin Invest 2014
6
Longterm Data on Sirolimus Treatment in Patients with Lupus Nephritis.
Desmond Y H Yap, Colin Tang, Gary C W Chan, Lorraine P Y Kwan, Maggie K M Ma, Maggie M Y Mok, Tak Mao Chan. J Rheumatol 2018
Desmond Y H Yap, Colin Tang, Gary C W Chan, Lorraine P Y Kwan, Maggie K M Ma, Maggie M Y Mok, Tak Mao Chan. J Rheumatol 2018
13
mTOR signaling in the differentiation and function of regulatory and effector T cells.
Hu Zeng, Hongbo Chi. Curr Opin Immunol 2017
Hu Zeng, Hongbo Chi. Curr Opin Immunol 2017
6
Differential Regulation of Human Treg and Th17 Cells by Fatty Acid Synthesis and Glycolysis.
Deborah Cluxton, Andreea Petrasca, Barry Moran, Jean M Fletcher. Front Immunol 2019
Deborah Cluxton, Andreea Petrasca, Barry Moran, Jean M Fletcher. Front Immunol 2019
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.