A citation-based method for searching scientific literature

Javier Ganz, Talya Shacham, Maria Kramer, Marina Shenkman, Hagit Eiger, Nitai Weinberg, Ori Iancovici, Somnath Roy, Luba Simhaev, Benny Da'adoosh, Hamutal Engel, Nisim Perets, Yael Barhum, Moshe Portnoy, Daniel Offen, Gerardo Z Lederkremer. Sci Rep 2020
Times Cited: 21







List of co-cited articles
296 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.
Helois Radford, Julie A Moreno, Nicholas Verity, Mark Halliday, Giovanna R Mallucci. Acta Neuropathol 2015
179
38

ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin.
Julia Leitman, Boaz Barak, Ron Benyair, Marina Shenkman, Uri Ashery, F Ulrich Hartl, Gerardo Z Lederkremer. PLoS One 2014
58
38

PERK activation mitigates tau pathology in vitro and in vivo.
Julius Bruch, Hong Xu, Thomas W Rösler, Anderson De Andrade, Peer-Hendrik Kuhn, Stefan F Lichtenthaler, Thomas Arzberger, Konstanze F Winklhofer, Ulrich Müller, Günter U Höglinger. EMBO Mol Med 2017
58
38

Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity.
Charity Atkins, Qi Liu, Elisabeth Minthorn, Shu-Yun Zhang, David J Figueroa, Katherine Moss, Thomas B Stanley, Brent Sanders, Aaron Goetz, Nathan Gaul,[...]. Cancer Res 2013
308
33


Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity.
M Halliday, H Radford, Y Sekine, J Moreno, N Verity, J le Quesne, C A Ortori, D A Barrett, C Fromont, P M Fischer,[...]. Cell Death Dis 2015
192
33

Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
Simon R Stockwell, Georgina Platt, S Elaine Barrie, Georgia Zoumpoulidou, Robert H Te Poele, G Wynne Aherne, Stuart C Wilson, Peter Sheldrake, Edward McDonald, Mathilde Venet,[...]. PLoS One 2012
62
33

Sustained translational repression by eIF2α-P mediates prion neurodegeneration.
Julie A Moreno, Helois Radford, Diego Peretti, Joern R Steinert, Nicholas Verity, Maria Guerra Martin, Mark Halliday, Jason Morgan, David Dinsdale, Catherine A Ortori,[...]. Nature 2012
437
33

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.
Mark Halliday, Helois Radford, Karlijn A M Zents, Collin Molloy, Julie A Moreno, Nicholas C Verity, Ewan Smith, Catharine A Ortori, David A Barrett, Martin Bushell,[...]. Brain 2017
173
33

Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease.
Gabriela Mercado, Valentina Castillo, Paulina Soto, Nélida López, Jeffrey M Axten, Sergio P Sardi, Jeroen J M Hoozemans, Claudio Hetz. Neurobiol Dis 2018
84
33

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
Michael Boyce, Kevin F Bryant, Céline Jousse, Kai Long, Heather P Harding, Donalyn Scheuner, Randal J Kaufman, Dawei Ma, Donald M Coen, David Ron,[...]. Science 2005
28

Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit.
Indrajit Das, Agnieszka Krzyzosiak, Kim Schneider, Lawrence Wrabetz, Maurizio D'Antonio, Nicholas Barry, Anna Sigurdardottir, Anne Bertolotti. Science 2015
265
28

Signal integration in the endoplasmic reticulum unfolded protein response.
David Ron, Peter Walter. Nat Rev Mol Cell Biol 2007
28


Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.
Rene L Vidal, Alicia Figueroa, Felipe A Court, Peter Thielen, Claudia Molina, Craig Wirth, Benjamin Caballero, Roberta Kiffin, Juan Segura-Aguilar, Ana Maria Cuervo,[...]. Hum Mol Genet 2012
195
28

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice.
Julie A Moreno, Mark Halliday, Colin Molloy, Helois Radford, Nicholas Verity, Jeffrey M Axten, Catharine A Ortori, Anne E Willis, Peter M Fischer, David A Barrett,[...]. Sci Transl Med 2013
409
23

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
Huikyong Lee, Jee-Yeon Noh, Yumin Oh, Youngdoo Kim, Jae-Woong Chang, Chul-Woong Chung, Soon-Tae Lee, Manho Kim, Hoon Ryu, Yong-Keun Jung. Hum Mol Genet 2012
109
23

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Alisa F Zyryanova, Félix Weis, Alexandre Faille, Akeel Abo Alard, Ana Crespillo-Casado, Yusuke Sekine, Heather P Harding, Felicity Allen, Leopold Parts, Christophe Fromont,[...]. Science 2018
95
23




Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming.
Julia M D Grandjean, Aparajita Madhavan, Lauren Cech, Bryan O Seguinot, Ryan J Paxman, Emery Smith, Louis Scampavia, Evan T Powers, Christina B Cooley, Lars Plate,[...]. Nat Chem Biol 2020
44
23

Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK).
Jeffrey M Axten, Jesús R Medina, Yanhong Feng, Arthur Shu, Stuart P Romeril, Seth W Grant, William Hoi Hong Li, Dirk A Heerding, Elisabeth Minthorn, Thomas Mencken,[...]. J Med Chem 2012
416
23

When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.
Diego Rojas-Rivera, Tinneke Delvaeye, Ria Roelandt, Wim Nerinckx, Koen Augustyns, Peter Vandenabeele, Mathieu J M Bertrand. Cell Death Differ 2017
102
23

The Unfolded Protein Response and Cell Fate Control.
Claudio Hetz, Feroz R Papa. Mol Cell 2018
668
23

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease.
Alisia Carnemolla, Elisa Fossale, Elena Agostoni, Silvia Michelazzi, Raffaella Calligaris, Luca De Maso, Giannino Del Sal, Marcy E MacDonald, Francesca Persichetti. J Biol Chem 2009
115
23


CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.
Stefan J Marciniak, Chi Y Yun, Seiichi Oyadomari, Isabel Novoa, Yuhong Zhang, Rivka Jungreis, Kazuhiro Nagata, Heather P Harding, David Ron. Genes Dev 2004
19


Small molecule ISRIB suppresses the integrated stress response within a defined window of activation.
Huib H Rabouw, Martijn A Langereis, Aditya A Anand, Linda J Visser, Raoul J de Groot, Peter Walter, Frank J M van Kuppeveld. Proc Natl Acad Sci U S A 2019
97
19

Pharmacological targeting of the unfolded protein response for disease intervention.
Claudio Hetz, Jeffrey M Axten, John B Patterson. Nat Chem Biol 2019
136
19

The impact of the unfolded protein response on human disease.
Shiyu Wang, Randal J Kaufman. J Cell Biol 2012
658
19

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis.
Eduardo Balsa, Meghan S Soustek, Ajith Thomas, Sara Cogliati, Carolina García-Poyatos, Elena Martín-García, Mark Jedrychowski, Steve P Gygi, José Antonio Enriquez, Pere Puigserver. Mol Cell 2019
118
19

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.
Rajarshi Ghosh, Likun Wang, Eric S Wang, B Gayani K Perera, Aeid Igbaria, Shuhei Morita, Kris Prado, Maike Thamsen, Deborah Caswell, Hector Macias,[...]. Cell 2014
312
19


Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.
Céline Jousse, Seiichi Oyadomari, Isabel Novoa, Phoebe Lu, Yuhong Zhang, Heather P Harding, David Ron. J Cell Biol 2003
226
19

eIF2B activator prevents neurological defects caused by a chronic integrated stress response.
Yao Liang Wong, Lauren LeBon, Ana M Basso, Kathy L Kohlhaas, Arthur L Nikkel, Holly M Robb, Diana L Donnelly-Roberts, Janani Prakash, Andrew M Swensen, Nimrod D Rubinstein,[...]. Elife 2019
69
19

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
Jordan C Tsai, Lakshmi E Miller-Vedam, Aditya A Anand, Priyadarshini Jaishankar, Henry C Nguyen, Adam R Renslo, Adam Frost, Peter Walter. Science 2018
90
19


Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
A Bertolotti, Y Zhang, L M Hendershot, H P Harding, D Ron. Nat Cell Biol 2000
19

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.
Mohamed Mahameed, Thomas Wilhelm, Odai Darawshi, Akram Obiedat, Weiss-Sadan Tommy, Chetan Chintha, Thomas Schubert, Afshin Samali, Eric Chevet, Leif A Eriksson,[...]. Cell Death Dis 2019
38
19


The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes.
Yao Liang Wong, Lauren LeBon, Rohinton Edalji, Hock Ben Lim, Chaohong Sun, Carmela Sidrauski. Elife 2018
57
19

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome.
M Delépine, M Nicolino, T Barrett, M Golamaully, G M Lathrop, C Julier. Nat Genet 2000
592
19

Pharmacological brake-release of mRNA translation enhances cognitive memory.
Carmela Sidrauski, Diego Acosta-Alvear, Arkady Khoutorsky, Punitha Vedantham, Brian R Hearn, Han Li, Karine Gamache, Ciara M Gallagher, Kenny K-H Ang, Chris Wilson,[...]. Elife 2013
382
19

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma.
Ioanna Papandreou, Nicholas C Denko, Michael Olson, Heleen Van Melckebeke, Sofie Lust, Arvin Tam, David E Solow-Cordero, Donna M Bouley, Fritz Offner, Maho Niwa,[...]. Blood 2011
357
19

PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz.
Ana Crespillo-Casado, Joseph E Chambers, Peter M Fischer, Stefan J Marciniak, David Ron. Elife 2017
63
19


ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Jaeseok Han, Sung Hoon Back, Junguk Hur, Yu-Hsuan Lin, Robert Gildersleeve, Jixiu Shan, Celvie L Yuan, Dawid Krokowski, Shiyu Wang, Maria Hatzoglou,[...]. Nat Cell Biol 2013
19

Mechanisms, regulation and functions of the unfolded protein response.
Claudio Hetz, Kezhong Zhang, Randal J Kaufman. Nat Rev Mol Cell Biol 2020
480
19


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.