A Takedachi, E Despras, S Scaglione, R Guérois, J H Guervilly, M Blin, S Audebert, L Camoin, Z Hasanova, M Schertzer, A Guille, D Churikov, I Callebaut, V Naim, M Chaffanet, J P Borg, F Bertucci, P Revy, D Birnbaum, A Londoño-Vallejo, P L Kannouche, P H L Gaillard. Nat Struct Mol Biol 2020
Times Cited: 14
Times Cited: 14
Times Cited
Times Co-cited
Similarity
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome.
Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan S Thakur, Esther Sanchez de Leon, Philipp H Richter, Liqun Ren, John H Petrini,[...]. Nat Struct Mol Biol 2020
Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan S Thakur, Esther Sanchez de Leon, Philipp H Richter, Liqun Ren, John H Petrini,[...]. Nat Struct Mol Biol 2020
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RTEL1 maintains genomic stability by suppressing homologous recombination.
Louise J Barber, Jillian L Youds, Jordan D Ward, Michael J McIlwraith, Nigel J O'Neil, Mark I R Petalcorin, Julie S Martin, Spencer J Collis, Sharon B Cantor, Melissa Auclair,[...]. Cell 2008
Louise J Barber, Jillian L Youds, Jordan D Ward, Michael J McIlwraith, Nigel J O'Neil, Mark I R Petalcorin, Julie S Martin, Spencer J Collis, Sharon B Cantor, Melissa Auclair,[...]. Cell 2008
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Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita.
Bari J Ballew, Meredith Yeager, Kevin Jacobs, Neelam Giri, Joseph Boland, Laurie Burdett, Blanche P Alter, Sharon A Savage. Hum Genet 2013
Bari J Ballew, Meredith Yeager, Kevin Jacobs, Neelam Giri, Joseph Boland, Laurie Burdett, Blanche P Alter, Sharon A Savage. Hum Genet 2013
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Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes.
Anne Helmrich, Monica Ballarino, Laszlo Tora. Mol Cell 2011
Anne Helmrich, Monica Ballarino, Laszlo Tora. Mol Cell 2011
35
RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication.
Jean-Baptiste Vannier, Sumit Sandhu, Mark I R Petalcorin, Xiaoli Wu, Zinnatun Nabi, Hao Ding, Simon J Boulton. Science 2013
Jean-Baptiste Vannier, Sumit Sandhu, Mark I R Petalcorin, Xiaoli Wu, Zinnatun Nabi, Hao Ding, Simon J Boulton. Science 2013
35
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.
Ivan M Muñoz, Karolina Hain, Anne-Cécile Déclais, Mary Gardiner, Geraldine W Toh, Luis Sanchez-Pulido, Johannes M Heuckmann, Rachel Toth, Thomas Macartney, Berina Eppink,[...]. Mol Cell 2009
Ivan M Muñoz, Karolina Hain, Anne-Cécile Déclais, Mary Gardiner, Geraldine W Toh, Luis Sanchez-Pulido, Johannes M Heuckmann, Rachel Toth, Thomas Macartney, Berina Eppink,[...]. Mol Cell 2009
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RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
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The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription.
Rebekka A Schwab, Jadwiga Nieminuszczy, Fenil Shah, Jamie Langton, David Lopez Martinez, Chih-Chao Liang, Martin A Cohn, Richard J Gibbons, Andrew J Deans, Wojciech Niedzwiedz. Mol Cell 2015
Rebekka A Schwab, Jadwiga Nieminuszczy, Fenil Shah, Jamie Langton, David Lopez Martinez, Chih-Chao Liang, Martin A Cohn, Richard J Gibbons, Andrew J Deans, Wojciech Niedzwiedz. Mol Cell 2015
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Localization-dependent and -independent roles of SLX4 in regulating telomeres.
Jamie S J Wilson, Agueda M Tejera, Dennis Castor, Rachel Toth, Maria A Blasco, John Rouse. Cell Rep 2013
Jamie S J Wilson, Agueda M Tejera, Dennis Castor, Rachel Toth, Maria A Blasco, John Rouse. Cell Rep 2013
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Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.
Zhong Deng, Galina Glousker, Aliah Molczan, Alan J Fox, Noa Lamm, Jayaraju Dheekollu, Orr-El Weizman, Michael Schertzer, Zhuo Wang, Olga Vladimirova,[...]. Proc Natl Acad Sci U S A 2013
Zhong Deng, Galina Glousker, Aliah Molczan, Alan J Fox, Noa Lamm, Jayaraju Dheekollu, Orr-El Weizman, Michael Schertzer, Zhuo Wang, Olga Vladimirova,[...]. Proc Natl Acad Sci U S A 2013
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RTEL1: functions of a disease-associated helicase.
Jean-Baptiste Vannier, Grzegorz Sarek, Simon J Boulton. Trends Cell Biol 2014
Jean-Baptiste Vannier, Grzegorz Sarek, Simon J Boulton. Trends Cell Biol 2014
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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
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Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses.
Stephan Hamperl, Michael J Bocek, Joshua C Saldivar, Tomek Swigut, Karlene A Cimprich. Cell 2017
Stephan Hamperl, Michael J Bocek, Joshua C Saldivar, Tomek Swigut, Karlene A Cimprich. Cell 2017
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TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
28
Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.
Kimiyo N Yamamoto, Shunsuke Kobayashi, Masataka Tsuda, Hitoshi Kurumizaka, Minoru Takata, Koichi Kono, Josef Jiricny, Shunichi Takeda, Kouji Hirota. Proc Natl Acad Sci U S A 2011
Kimiyo N Yamamoto, Shunsuke Kobayashi, Masataka Tsuda, Hitoshi Kurumizaka, Minoru Takata, Koichi Kono, Josef Jiricny, Shunichi Takeda, Kouji Hirota. Proc Natl Acad Sci U S A 2011
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R-loops induce repressive chromatin marks over mammalian gene terminators.
Konstantina Skourti-Stathaki, Kinga Kamieniarz-Gdula, Nicholas J Proudfoot. Nature 2014
Konstantina Skourti-Stathaki, Kinga Kamieniarz-Gdula, Nicholas J Proudfoot. Nature 2014
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R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
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Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.
Anne Letessier, Gaël A Millot, Stéphane Koundrioukoff, Anne-Marie Lachagès, Nicolas Vogt, R Scott Hansen, Bernard Malfoy, Olivier Brison, Michelle Debatisse. Nature 2011
Anne Letessier, Gaël A Millot, Stéphane Koundrioukoff, Anne-Marie Lachagès, Nicolas Vogt, R Scott Hansen, Bernard Malfoy, Olivier Brison, Michelle Debatisse. Nature 2011
21
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
Margaret Wrensch, Robert B Jenkins, Jeffrey S Chang, Ru-Fang Yeh, Yuanyuan Xiao, Paul A Decker, Karla V Ballman, Mitchel Berger, Jan C Buckner, Susan Chang,[...]. Nat Genet 2009
Margaret Wrensch, Robert B Jenkins, Jeffrey S Chang, Ru-Fang Yeh, Yuanyuan Xiao, Paul A Decker, Karla V Ballman, Mitchel Berger, Jan C Buckner, Susan Chang,[...]. Nat Genet 2009
21
Genome-wide association study identifies five susceptibility loci for glioma.
Sanjay Shete, Fay J Hosking, Lindsay B Robertson, Sara E Dobbins, Marc Sanson, Beatrice Malmer, Matthias Simon, Yannick Marie, Blandine Boisselier, Jean-Yves Delattre,[...]. Nat Genet 2009
Sanjay Shete, Fay J Hosking, Lindsay B Robertson, Sara E Dobbins, Marc Sanson, Beatrice Malmer, Matthias Simon, Yannick Marie, Blandine Boisselier, Jean-Yves Delattre,[...]. Nat Genet 2009
21
Replication stress activates DNA repair synthesis in mitosis.
Sheroy Minocherhomji, Songmin Ying, Victoria A Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W Mankouri, Huahao Shen, Ying Liu, Ian D Hickson. Nature 2015
Sheroy Minocherhomji, Songmin Ying, Victoria A Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W Mankouri, Huahao Shen, Ying Liu, Ian D Hickson. Nature 2015
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R loops: from transcription byproducts to threats to genome stability.
Andrés Aguilera, Tatiana García-Muse. Mol Cell 2012
Andrés Aguilera, Tatiana García-Muse. Mol Cell 2012
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Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
21
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination.
Konstantina Skourti-Stathaki, Nicholas J Proudfoot, Natalia Gromak. Mol Cell 2011
Konstantina Skourti-Stathaki, Nicholas J Proudfoot, Natalia Gromak. Mol Cell 2011
21
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
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Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations.
Sarah Cohen, Nadine Puget, Yea-Lih Lin, Thomas Clouaire, Marion Aguirrebengoa, Vincent Rocher, Philippe Pasero, Yvan Canitrot, Gaëlle Legube. Nat Commun 2018
Sarah Cohen, Nadine Puget, Yea-Lih Lin, Thomas Clouaire, Marion Aguirrebengoa, Vincent Rocher, Philippe Pasero, Yvan Canitrot, Gaëlle Legube. Nat Commun 2018
21
Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.
Özlem Yüce, Stephen C West. Mol Cell Biol 2013
Özlem Yüce, Stephen C West. Mol Cell Biol 2013
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An oncogene-induced DNA damage model for cancer development.
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
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A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome.
Bari J Ballew, Vijai Joseph, Saurav De, Grzegorz Sarek, Jean-Baptiste Vannier, Travis Stracker, Kasmintan A Schrader, Trudy N Small, Richard O'Reilly, Chris Manschreck,[...]. PLoS Genet 2013
Bari J Ballew, Vijai Joseph, Saurav De, Grzegorz Sarek, Jean-Baptiste Vannier, Travis Stracker, Kasmintan A Schrader, Trudy N Small, Richard O'Reilly, Chris Manschreck,[...]. PLoS Genet 2013
21
Human RTEL1 deficiency causes Hoyeraal-Hreidarsson syndrome with short telomeres and genome instability.
Tangui Le Guen, Laurent Jullien, Fabien Touzot, Michael Schertzer, Laetitia Gaillard, Mylène Perderiset, Wassila Carpentier, Patrick Nitschke, Capucine Picard, Gérard Couillault,[...]. Hum Mol Genet 2013
Tangui Le Guen, Laurent Jullien, Fabien Touzot, Michael Schertzer, Laetitia Gaillard, Mylène Perderiset, Wassila Carpentier, Patrick Nitschke, Capucine Picard, Gérard Couillault,[...]. Hum Mol Genet 2013
21
RTEL1 contributes to DNA replication and repair and telomere maintenance.
Evert-Jan Uringa, Kathleen Lisaingo, Hilda A Pickett, Julie Brind'Amour, Jan-Hendrik Rohde, Alex Zelensky, Jeroen Essers, Peter M Lansdorp. Mol Biol Cell 2012
Evert-Jan Uringa, Kathleen Lisaingo, Hilda A Pickett, Julie Brind'Amour, Jan-Hendrik Rohde, Alex Zelensky, Jeroen Essers, Peter M Lansdorp. Mol Biol Cell 2012
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Constitutional mutations in RTEL1 cause severe dyskeratosis congenita.
Amanda J Walne, Tom Vulliamy, Michael Kirwan, Vincent Plagnol, Inderjeet Dokal. Am J Hum Genet 2013
Amanda J Walne, Tom Vulliamy, Michael Kirwan, Vincent Plagnol, Inderjeet Dokal. Am J Hum Genet 2013
21
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein.
Hao Ding, Mike Schertzer, Xiaoli Wu, Marina Gertsenstein, Sara Selig, Makoto Kammori, Reza Pourvali, Steven Poon, Irma Vulto, Elizabeth Chavez,[...]. Cell 2004
Hao Ding, Mike Schertzer, Xiaoli Wu, Marina Gertsenstein, Sara Selig, Makoto Kammori, Reza Pourvali, Steven Poon, Irma Vulto, Elizabeth Chavez,[...]. Cell 2004
21
SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites.
Román González-Prieto, Sabine A G Cuijpers, Martijn S Luijsterburg, Haico van Attikum, Alfred C O Vertegaal. EMBO Rep 2015
Román González-Prieto, Sabine A G Cuijpers, Martijn S Luijsterburg, Haico van Attikum, Alfred C O Vertegaal. EMBO Rep 2015
21
SLX4: multitasking to maintain genome stability.
Jean-Hugues Guervilly, Pierre Henri Gaillard. Crit Rev Biochem Mol Biol 2018
Jean-Hugues Guervilly, Pierre Henri Gaillard. Crit Rev Biochem Mol Biol 2018
21
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.
Samira Fekairi, Sarah Scaglione, Charly Chahwan, Ewan R Taylor, Agnès Tissier, Stéphane Coulon, Meng-Qiu Dong, Cristian Ruse, John R Yates, Paul Russell,[...]. Cell 2009
Samira Fekairi, Sarah Scaglione, Charly Chahwan, Ewan R Taylor, Agnès Tissier, Stéphane Coulon, Meng-Qiu Dong, Cristian Ruse, John R Yates, Paul Russell,[...]. Cell 2009
21
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Jennifer M Svendsen, Agata Smogorzewska, Mathew E Sowa, Brenda C O'Connell, Steven P Gygi, Stephen J Elledge, J Wade Harper. Cell 2009
Jennifer M Svendsen, Agata Smogorzewska, Mathew E Sowa, Brenda C O'Connell, Steven P Gygi, Stephen J Elledge, J Wade Harper. Cell 2009
21
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.
Michael R G Hodskinson, Jan Silhan, Gerry P Crossan, Juan I Garaycoechea, Shivam Mukherjee, Christopher M Johnson, Orlando D Schärer, Ketan J Patel. Mol Cell 2014
Michael R G Hodskinson, Jan Silhan, Gerry P Crossan, Juan I Garaycoechea, Shivam Mukherjee, Christopher M Johnson, Orlando D Schärer, Ketan J Patel. Mol Cell 2014
21
Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.
Dennis Castor, Nidhi Nair, Anne-Cécile Déclais, Christophe Lachaud, Rachel Toth, Thomas J Macartney, David M J Lilley, J Simon C Arthur, John Rouse. Mol Cell 2013
Dennis Castor, Nidhi Nair, Anne-Cécile Déclais, Christophe Lachaud, Rachel Toth, Thomas J Macartney, David M J Lilley, J Simon C Arthur, John Rouse. Mol Cell 2013
21
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype.
Chantal Stoepker, Karolina Hain, Beatrice Schuster, Yvonne Hilhorst-Hofstee, Martin A Rooimans, Jurgen Steltenpool, Anneke B Oostra, Katharina Eirich, Elisabeth T Korthof, Aggie W M Nieuwint,[...]. Nat Genet 2011
Chantal Stoepker, Karolina Hain, Beatrice Schuster, Yvonne Hilhorst-Hofstee, Martin A Rooimans, Jurgen Steltenpool, Anneke B Oostra, Katharina Eirich, Elisabeth T Korthof, Aggie W M Nieuwint,[...]. Nat Genet 2011
21
Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells.
Haley D M Wyatt, Shriparna Sarbajna, Joao Matos, Stephen C West. Mol Cell 2013
Haley D M Wyatt, Shriparna Sarbajna, Joao Matos, Stephen C West. Mol Cell 2013
21
Mutations of the SLX4 gene in Fanconi anemia.
Yonghwan Kim, Francis P Lach, Rohini Desetty, Helmut Hanenberg, Arleen D Auerbach, Agata Smogorzewska. Nat Genet 2011
Yonghwan Kim, Francis P Lach, Rohini Desetty, Helmut Hanenberg, Arleen D Auerbach, Agata Smogorzewska. Nat Genet 2011
21
Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions.
Elizabeth Garner, Yonghwan Kim, Francis P Lach, Molly C Kottemann, Agata Smogorzewska. Cell Rep 2013
Elizabeth Garner, Yonghwan Kim, Francis P Lach, Molly C Kottemann, Agata Smogorzewska. Cell Rep 2013
21
BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.
Alexander P Sobinoff, Joshua Am Allen, Axel A Neumann, Sile F Yang, Monica E Walsh, Jeremy D Henson, Roger R Reddel, Hilda A Pickett. EMBO J 2017
Alexander P Sobinoff, Joshua Am Allen, Axel A Neumann, Sile F Yang, Monica E Walsh, Jeremy D Henson, Roger R Reddel, Hilda A Pickett. EMBO J 2017
21
SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
Stephanie Panier, Marija Maric, Graeme Hewitt, Emily Mason-Osann, Himabindu Gali, Anqi Dai, Adam Labadorf, Jean-Hugues Guervilly, Philip Ruis, Sandra Segura-Bayona,[...]. Mol Cell 2019
Stephanie Panier, Marija Maric, Graeme Hewitt, Emily Mason-Osann, Himabindu Gali, Anqi Dai, Adam Labadorf, Jean-Hugues Guervilly, Philip Ruis, Sandra Segura-Bayona,[...]. Mol Cell 2019
21
SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.
Bingbing Wan, Jinhu Yin, Kent Horvath, Jaya Sarkar, Yong Chen, Jian Wu, Ke Wan, Jian Lu, Peili Gu, Eun Young Yu,[...]. Cell Rep 2013
Bingbing Wan, Jinhu Yin, Kent Horvath, Jaya Sarkar, Yong Chen, Jian Wu, Ke Wan, Jian Lu, Peili Gu, Eun Young Yu,[...]. Cell Rep 2013
21
SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.
Huimin Zhang, Zhen Chen, Yin Ye, Zu Ye, Dan Cao, Yun Xiong, Mrinal Srivastava, Xu Feng, Mengfan Tang, Chao Wang,[...]. Nucleic Acids Res 2019
Huimin Zhang, Zhen Chen, Yin Ye, Zu Ye, Dan Cao, Yun Xiong, Mrinal Srivastava, Xu Feng, Mengfan Tang, Chao Wang,[...]. Nucleic Acids Res 2019
21
SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates.
Jaya Sarkar, Bingbing Wan, Jinhu Yin, Haritha Vallabhaneni, Kent Horvath, Tomasz Kulikowicz, Vilhelm A Bohr, Yanbin Zhang, Ming Lei, Yie Liu. Nucleic Acids Res 2015
Jaya Sarkar, Bingbing Wan, Jinhu Yin, Haritha Vallabhaneni, Kent Horvath, Tomasz Kulikowicz, Vilhelm A Bohr, Yanbin Zhang, Ming Lei, Yie Liu. Nucleic Acids Res 2015
21
RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.
Claudia Ribeiro de Almeida, Somdutta Dhir, Ashish Dhir, Amin E Moghaddam, Quentin Sattentau, Anton Meinhart, Nicholas J Proudfoot. Mol Cell 2018
Claudia Ribeiro de Almeida, Somdutta Dhir, Ashish Dhir, Amin E Moghaddam, Quentin Sattentau, Anton Meinhart, Nicholas J Proudfoot. Mol Cell 2018
21
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.