A citation-based method for searching scientific literature

Claudio Hetz, Kezhong Zhang, Randal J Kaufman. Nat Rev Mol Cell Biol 2020
Times Cited: 303







List of co-cited articles
550 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity





CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.
Stefan J Marciniak, Chi Y Yun, Seiichi Oyadomari, Isabel Novoa, Yuhong Zhang, Rivka Jungreis, Kazuhiro Nagata, Heather P Harding, David Ron. Genes Dev 2004
10

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.
F Urano, X Wang, A Bertolotti, Y Zhang, P Chung, H P Harding, D Ron. Science 2000
10

The Unfolded Protein Response and Cell Fate Control.
Claudio Hetz, Feroz R Papa. Mol Cell 2018
576
10


IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA.
Marcella Calfon, Huiqing Zeng, Fumihiko Urano, Jeffery H Till, Stevan R Hubbard, Heather P Harding, Scott G Clark, David Ron. Nature 2002
9


The endoplasmic reticulum: structure, function and response to cellular signaling.
Dianne S Schwarz, Michael D Blower. Cell Mol Life Sci 2016
440
9


Protein quality control in the secretory pathway.
Zhihao Sun, Jeffrey L Brodsky. J Cell Biol 2019
123
8


An integrated stress response regulates amino acid metabolism and resistance to oxidative stress.
Heather P Harding, Yuhong Zhang, Huiquing Zeng, Isabel Novoa, Phoebe D Lu, Marcella Calfon, Navid Sadri, Chi Yun, Brian Popko, Richard Paules,[...]. Mol Cell 2003
7



IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Alana G Lerner, John-Paul Upton, P V K Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J Backes, Myriam Heiman,[...]. Cell Metab 2012
532
7


Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments.
Matthew D Shoulders, Lisa M Ryno, Joseph C Genereux, James J Moresco, Patricia G Tu, Chunlei Wu, John R Yates, Andrew I Su, Jeffery W Kelly, R Luke Wiseman. Cell Rep 2013
317
7

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Amado Carreras-Sureda, Fabián Jaña, Hery Urra, Sylvere Durand, David E Mortenson, Alfredo Sagredo, Galdo Bustos, Younis Hazari, Eva Ramos-Fernández, Maria L Sassano,[...]. Nat Cell Biol 2019
98
6

Mediators of endoplasmic reticulum stress-induced apoptosis.
Eva Szegezdi, Susan E Logue, Adrienne M Gorman, Afshin Samali. EMBO Rep 2006
6

Protein folding and modification in the mammalian endoplasmic reticulum.
Ineke Braakman, Neil J Bulleid. Annu Rev Biochem 2011
407
6

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
A Bertolotti, Y Zhang, L M Hendershot, H P Harding, D Ron. Nat Cell Biol 2000
6

The integrated stress response: From mechanism to disease.
Mauro Costa-Mattioli, Peter Walter. Science 2020
202
6

Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.
Rajarshi Ghosh, Likun Wang, Eric S Wang, B Gayani K Perera, Aeid Igbaria, Shuhei Morita, Kris Prado, Maike Thamsen, Deborah Caswell, Hector Macias,[...]. Cell 2014
285
6

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications.
Aitor Almanza, Antonio Carlesso, Chetan Chintha, Stuart Creedican, Dimitrios Doultsinos, Brian Leuzzi, Andreia Luís, Nicole McCarthy, Luigi Montibeller, Sanket More,[...]. FEBS J 2019
275
6

ER stress and the unfolded protein response in neurodegeneration.
Claudio Hetz, Smita Saxena. Nat Rev Neurol 2017
383
6

The role of endoplasmic reticulum stress in human pathology.
Scott A Oakes, Feroz R Papa. Annu Rev Pathol 2015
515
6

Getting RIDD of RNA: IRE1 in cell fate regulation.
M Maurel, E Chevet, J Tavernier, S Gerlo. Trends Biochem Sci 2014
328
6

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.
Jaeseok Han, Sung Hoon Back, Junguk Hur, Yu-Hsuan Lin, Robert Gildersleeve, Jixiu Shan, Celvie L Yuan, Dawid Krokowski, Shiyu Wang, Maria Hatzoglou,[...]. Nat Cell Biol 2013
930
6

Proteostasis control by the unfolded protein response.
Claudio Hetz, Eric Chevet, Scott A Oakes. Nat Cell Biol 2015
405
5

Pharmacological targeting of the unfolded protein response for disease intervention.
Claudio Hetz, Jeffrey M Axten, John B Patterson. Nat Chem Biol 2019
111
5

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Hery Urra, Daniel R Henriquez, José Cánovas, David Villarroel-Campos, Amado Carreras-Sureda, Eduardo Pulgar, Emiliano Molina, Younis M Hazari, Celia M Limia, Sebastián Alvarez-Rojas,[...]. Nat Cell Biol 2018
60
8

IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis.
Debanjali Dasgupta, Yasuhiko Nakao, Amy S Mauer, Jill M Thompson, Tejasav S Sehrawat, Chieh-Yu Liao, Anuradha Krishnan, Fabrice Lucien, Qianqian Guo, Mengfei Liu,[...]. Gastroenterology 2020
41
12

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells.
Krishna M Vattem, Ronald C Wek. Proc Natl Acad Sci U S A 2004
5


The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
5

Mitochondria as multifaceted regulators of cell death.
Florian J Bock, Stephen W G Tait. Nat Rev Mol Cell Biol 2020
396
5

Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1.
Christopher J Adams, Megan C Kopp, Natacha Larburu, Piotr R Nowak, Maruf M U Ali. Front Mol Biosci 2019
144
5

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.
Denise N Bronner, Basel H Abuaita, Xiaoyun Chen, Katherine A Fitzgerald, Gabriel Nuñez, Yongqun He, Xiao-Ming Yin, Mary X D O'Riordan. Immunity 2015
215
5

IRE1 signaling affects cell fate during the unfolded protein response.
Jonathan H Lin, Han Li, Douglas Yasumura, Hannah R Cohen, Chao Zhang, Barbara Panning, Kevan M Shokat, Matthew M Lavail, Peter Walter. Science 2007
987
5



Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming.
Julia M D Grandjean, Aparajita Madhavan, Lauren Cech, Bryan O Seguinot, Ryan J Paxman, Emery Smith, Louis Scampavia, Evan T Powers, Christina B Cooley, Lars Plate,[...]. Nat Chem Biol 2020
27
18

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.
Keisuke Yamamoto, Takashi Sato, Toshie Matsui, Masanori Sato, Tetsuya Okada, Hiderou Yoshida, Akihiro Harada, Kazutoshi Mori. Dev Cell 2007
718
5


IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
John-Paul Upton, Likun Wang, Dan Han, Eric S Wang, Noelle E Huskey, Lionel Lim, Morgan Truitt, Michael T McManus, Davide Ruggero, Andrei Goga,[...]. Science 2012
426
4

Small molecule ISRIB suppresses the integrated stress response within a defined window of activation.
Huib H Rabouw, Martijn A Langereis, Aditya A Anand, Linda J Visser, Raoul J de Groot, Peter Walter, Frank J M van Kuppeveld. Proc Natl Acad Sci U S A 2019
78
5

eIF2α phosphorylation is pathognomonic for immunogenic cell death.
Lucillia Bezu, Allan Sauvat, Juliette Humeau, Lígia C Gomes-da-Silva, Kristina Iribarren, Sabrina Forveille, Pauline Garcia, Liwei Zhao, Peng Liu, Laurence Zitvogel,[...]. Cell Death Differ 2018
84
4

The integrated stress response.
Karolina Pakos-Zebrucka, Izabela Koryga, Katarzyna Mnich, Mila Ljujic, Afshin Samali, Adrienne M Gorman. EMBO Rep 2016
850
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.