A citation-based method for searching scientific literature

Maud Gratuze, Cheryl Eg Leyns, Andrew D Sauerbeck, Marie-Kim St-Pierre, Monica Xiong, Nayeon Kim, Javier Remolina Serrano, Marie-Ève Tremblay, Terrance T Kummer, Marco Colonna, Jason D Ulrich, David M Holtzman. J Clin Invest 2020
Times Cited: 71







List of co-cited articles
1140 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
60

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
47

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
43

Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
42

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.
Cheryl E G Leyns, Jason D Ulrich, Mary B Finn, Floy R Stewart, Lauren J Koscal, Javier Remolina Serrano, Grace O Robinson, Elise Anderson, Marco Colonna, David M Holtzman. Proc Natl Acad Sci U S A 2017
212
40

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
868
38

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan,[...]. J Exp Med 2016
394
35

TREM2 function impedes tau seeding in neuritic plaques.
Cheryl E G Leyns, Maud Gratuze, Sneha Narasimhan, Nimansha Jain, Lauren J Koscal, Hong Jiang, Melissa Manis, Marco Colonna, Virginia M Y Lee, Jason D Ulrich,[...]. Nat Neurosci 2019
104
29

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Peng Yuan, Carlo Condello, C Dirk Keene, Yaming Wang, Thomas D Bird, Steven M Paul, Wenjie Luo, Marco Colonna, David Baddeley, Jaime Grutzendler. Neuron 2016
328
29

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
Shoutang Wang, Meer Mustafa, Carla M Yuede, Santiago Viveros Salazar, Philip Kong, Hua Long, Michael Ward, Omer Siddiqui, Robert Paul, Susan Gilfillan,[...]. J Exp Med 2020
106
28

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M Holtzman. J Exp Med 2019
136
28

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan,[...]. Nat Med 2020
295
28

TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy.
Shane M Bemiller, Tyler J McCray, Kevin Allan, Shane V Formica, Guixiang Xu, Gina Wilson, Olga N Kokiko-Cochran, Samuel D Crish, Cristian A Lasagna-Reeves, Richard M Ransohoff,[...]. Mol Neurodegener 2017
133
26

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
Taylor R Jay, Crystal M Miller, Paul J Cheng, Leah C Graham, Shane Bemiller, Margaret L Broihier, Guixiang Xu, Daniel Margevicius, J Colleen Karlo, Gregory L Sousa,[...]. J Exp Med 2015
427
26

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Tyler K Ulland, Wilbur M Song, Stanley Ching-Cheng Huang, Jason D Ulrich, Alexey Sergushichev, Wandy L Beatty, Alexander A Loboda, Yingyue Zhou, Nigel J Cairns, Amal Kambal,[...]. Cell 2017
493
25

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
Taylor R Jay, Anna M Hirsch, Margaret L Broihier, Crystal M Miller, Lee E Neilson, Richard M Ransohoff, Bruce T Lamb, Gary E Landreth. J Neurosci 2017
236
25

Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
23

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti-Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner,[...]. EMBO Mol Med 2020
82
23

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
995
22

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
541
22

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model.
Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C Saido, Jun Maeda, Tetsuya Suhara, John Q Trojanowski, Virginia M-Y Lee. Neuron 2007
22

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan C Piña-Crespo, Muxian Zhang,[...]. Neuron 2018
289
22



TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Ana Griciuc, Shaun Patel, Anthony N Federico, Se Hoon Choi, Brendan J Innes, Mary K Oram, Gea Cereghetti, Danielle McGinty, Anthony Anselmo, Ruslan I Sadreyev,[...]. Neuron 2019
134
19

TREM2 - a key player in microglial biology and Alzheimer disease.
Tyler K Ulland, Marco Colonna. Nat Rev Neurol 2018
231
19

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit. Cell 2018
429
19

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Rebecca Sims, Sven J van der Lee, Adam C Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W Kunkle, Anne Boland, Rachel Raybould, Joshua C Bis,[...]. Nat Genet 2017
498
19

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.
Faten A Sayed, Maria Telpoukhovskaia, Lay Kodama, Yaqiao Li, Yungui Zhou, David Le, Axel Hauduc, Connor Ludwig, Fuying Gao, Claire Clelland,[...]. Proc Natl Acad Sci U S A 2018
69
20

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski,[...]. Nat Neurosci 2019
222
19

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.
Fabia Filipello, Raffaella Morini, Irene Corradini, Valerio Zerbi, Alice Canzi, Bernadeta Michalski, Marco Erreni, Marija Markicevic, Chiara Starvaggi-Cucuzza, Karel Otero,[...]. Immunity 2018
251
18

Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Hirohide Asai, Seiko Ikezu, Satoshi Tsunoda, Maria Medalla, Jennifer Luebke, Tarik Haydar, Benjamin Wolozin, Oleg Butovsky, Sebastian Kügler, Tsuneya Ikezu. Nat Neurosci 2015
829
18

New insights into the role of TREM2 in Alzheimer's disease.
Maud Gratuze, Cheryl E G Leyns, David M Holtzman. Mol Neurodegener 2018
190
18

Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
William J Meilandt, Hai Ngu, Alvin Gogineni, Guita Lalehzadeh, Seung-Hye Lee, Karpagam Srinivasan, Jose Imperio, Tiffany Wu, Martin Weber, Agatha J Kruse,[...]. J Neurosci 2020
56
23


NLRP3 inflammasome activation drives tau pathology.
Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera,[...]. Nature 2019
430
16

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, Eva Czirr, Ebba Lohmann, Elise Cuyvers, Hanne Struyfs, Nadine Pettkus, Andrea Wenninger-Weinzierl, Fargol Mazaheri,[...]. Sci Transl Med 2014
452
16

Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
16

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.
Jason D Ulrich, Mary Beth Finn, Yaming Wang, Alice Shen, Thomas E Mahan, Hong Jiang, Floy R Stewart, Laura Piccio, Marco Colonna, David M Holtzman. Mol Neurodegener 2014
203
16

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Alicia A Nugent, Karin Lin, Bettina van Lengerich, Steve Lianoglou, Laralynne Przybyla, Sonnet S Davis, Ceyda Llapashtica, Junhua Wang, Do Jin Kim, Dan Xia,[...]. Neuron 2020
178
15

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
Michael Ewers, Nicolai Franzmeier, Marc Suárez-Calvet, Estrella Morenas-Rodriguez, Miguel Angel Araque Caballero, Gernot Kleinberger, Laura Piccio, Carlos Cruchaga, Yuetiva Deming, Martin Dichgans,[...]. Sci Transl Med 2019
118
15

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu,[...]. J Biol Chem 2015
276
15

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain.
Nicole Maphis, Guixiang Xu, Olga N Kokiko-Cochran, Shanya Jiang, Astrid Cardona, Richard M Ransohoff, Bruce T Lamb, Kiran Bhaskar. Brain 2015
285
15

The microglial sensome revealed by direct RNA sequencing.
Suzanne E Hickman, Nathan D Kingery, Toshiro K Ohsumi, Mark L Borowsky, Li-chong Wang, Terry K Means, Joseph El Khoury. Nat Neurosci 2013
900
15

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Elizabeth Spangenberg, Paul L Severson, Lindsay A Hohsfield, Joshua Crapser, Jiazhong Zhang, Elizabeth A Burton, Ying Zhang, Wayne Spevak, Jack Lin, Nicole Y Phan,[...]. Nat Commun 2019
265
15

Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
15

Single-cell transcriptomic analysis of Alzheimer's disease.
Hansruedi Mathys, Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z Young, Madhvi Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang,[...]. Nature 2019
742
15

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Borislav Dejanovic, Melanie A Huntley, Ann De Mazière, William J Meilandt, Tiffany Wu, Karpagam Srinivasan, Zhiyu Jiang, Vineela Gandham, Brad A Friedman, Hai Ngu,[...]. Neuron 2018
189
14

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner.
Dorothy P Schafer, Emily K Lehrman, Amanda G Kautzman, Ryuta Koyama, Alan R Mardinly, Ryo Yamasaki, Richard M Ransohoff, Michael E Greenberg, Ben A Barres, Beth Stevens. Neuron 2012
14

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Simon Dujardin, Caitlin Commins, Aurelien Lathuiliere, Pieter Beerepoot, Analiese R Fernandes, Tarun V Kamath, Mark B De Los Santos, Naomi Klickstein, Diana L Corjuc, Bianca T Corjuc,[...]. Nat Med 2020
148
14


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.