Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion.
Anna Niewiadomska-Cimicka, Antoine Hache, Yvon Trottier. Front Neurosci 2020
Times Cited: 5
Times Cited: 5
Times Cited
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Pathogenesis of SCA3 and implications for other polyglutamine diseases.
Hayley S McLoughlin, Lauren R Moore, Henry L Paulson. Neurobiol Dis 2020
Hayley S McLoughlin, Lauren R Moore, Henry L Paulson. Neurobiol Dis 2020
80
Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7.
Pavitra S Ramachandran, Ryan L Boudreau, Kellie A Schaefer, Albert R La Spada, Beverly L Davidson. Mol Ther 2014
Pavitra S Ramachandran, Ryan L Boudreau, Kellie A Schaefer, Albert R La Spada, Beverly L Davidson. Mol Ther 2014
60
An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron.
Yu Miyazaki, Xiaofei Du, Shin-Ichi Muramatsu, Christopher M Gomez. Sci Transl Med 2016
Yu Miyazaki, Xiaofei Du, Shin-Ichi Muramatsu, Christopher M Gomez. Sci Transl Med 2016
60
Targeting potassium channels to treat cerebellar ataxia.
David D Bushart, Ravi Chopra, Vikrant Singh, Geoffrey G Murphy, Heike Wulff, Vikram G Shakkottai. Ann Clin Transl Neurol 2018
David D Bushart, Ravi Chopra, Vikrant Singh, Geoffrey G Murphy, Heike Wulff, Vikram G Shakkottai. Ann Clin Transl Neurol 2018
60
Broad therapeutic benefit after RNAi expression vector delivery to deep cerebellar nuclei: implications for spinocerebellar ataxia type 1 therapy.
Megan S Keiser, Ryan L Boudreau, Beverly L Davidson. Mol Ther 2014
Megan S Keiser, Ryan L Boudreau, Beverly L Davidson. Mol Ther 2014
60
Antisense oligonucleotide therapy for spinocerebellar ataxia type 2.
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis,[...]. Nature 2017
60
Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Maria do Carmo Costa, Katiuska Luna-Cancalon, Svetlana Fischer, Naila S Ashraf, Michelle Ouyang, Rahil M Dharia, Lucas Martin-Fishman, Yemen Yang, Vikram G Shakkottai, Beverly L Davidson,[...]. Mol Ther 2013
Maria do Carmo Costa, Katiuska Luna-Cancalon, Svetlana Fischer, Naila S Ashraf, Michelle Ouyang, Rahil M Dharia, Lucas Martin-Fishman, Yemen Yang, Vikram G Shakkottai, Beverly L Davidson,[...]. Mol Ther 2013
60
Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
Alice Chort, Sandro Alves, Martina Marinello, Béatrice Dufresnois, Jean-Gabriel Dornbierer, Christelle Tesson, Morwena Latouche, Darren P Baker, Martine Barkats, Khalid H El Hachimi,[...]. Brain 2013
Alice Chort, Sandro Alves, Martina Marinello, Béatrice Dufresnois, Jean-Gabriel Dornbierer, Christelle Tesson, Morwena Latouche, Darren P Baker, Martine Barkats, Khalid H El Hachimi,[...]. Brain 2013
60
CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells.
Shuming Ouyang, Yingjun Xie, Zeyu Xiong, Yi Yang, Yexing Xian, Zhanhui Ou, Bing Song, Yuchang Chen, Yuhuan Xie, Haoxian Li,[...]. Stem Cells Dev 2018
Shuming Ouyang, Yingjun Xie, Zeyu Xiong, Yi Yang, Yexing Xian, Zhanhui Ou, Bing Song, Yuchang Chen, Yuhuan Xie, Haoxian Li,[...]. Stem Cells Dev 2018
60
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.
Haibin Xia, Qinwen Mao, Steven L Eliason, Scott Q Harper, Inês H Martins, Harry T Orr, Henry L Paulson, Linda Yang, Robert M Kotin, Beverly L Davidson. Nat Med 2004
Haibin Xia, Qinwen Mao, Steven L Eliason, Scott Q Harper, Inês H Martins, Harry T Orr, Henry L Paulson, Linda Yang, Robert M Kotin, Beverly L Davidson. Nat Med 2004
60
Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
Kei Watase, Jennifer R Gatchel, Yaling Sun, Effat Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T Orr, Chad Shaw, Huda Y Zoghbi. PLoS Med 2007
Kei Watase, Jennifer R Gatchel, Yaling Sun, Effat Emamian, Richard Atkinson, Ronald Richman, Hidehiro Mizusawa, Harry T Orr, Chad Shaw, Huda Y Zoghbi. PLoS Med 2007
60
Spinocerebellar ataxias: prospects and challenges for therapy development.
Tetsuo Ashizawa, Gülin Öz, Henry L Paulson. Nat Rev Neurol 2018
Tetsuo Ashizawa, Gülin Öz, Henry L Paulson. Nat Rev Neurol 2018
60
Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.
Hayley S McLoughlin, Lauren R Moore, Ravi Chopra, Robert Komlo, Megan McKenzie, Kate G Blumenstein, Hien Zhao, Holly B Kordasiewicz, Vikram G Shakkottai, Henry L Paulson. Ann Neurol 2018
Hayley S McLoughlin, Lauren R Moore, Ravi Chopra, Robert Komlo, Megan McKenzie, Kate G Blumenstein, Hien Zhao, Holly B Kordasiewicz, Vikram G Shakkottai, Henry L Paulson. Ann Neurol 2018
60
Spinocerebellar ataxia: an update.
Roisin Sullivan, Wai Yan Yau, Emer O'Connor, Henry Houlden. J Neurol 2019
Roisin Sullivan, Wai Yan Yau, Emer O'Connor, Henry Houlden. J Neurol 2019
60
From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation.
Jorge Diogo Da Silva, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2019
Jorge Diogo Da Silva, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2019
60
Cellular and circuit mechanisms underlying spinocerebellar ataxias.
Pratap Meera, Stefan M Pulst, Thomas S Otis. J Physiol 2016
Pratap Meera, Stefan M Pulst, Thomas S Otis. J Physiol 2016
60
Polyglutamine-expanded ataxin-7 causes cerebellar dysfunction by inducing transcriptional dysregulation.
An-Hsun Chou, Chia-Yang Chen, Si-Ying Chen, Wei-June Chen, Ying-Ling Chen, Yi-Shin Weng, Hung-Li Wang. Neurochem Int 2010
An-Hsun Chou, Chia-Yang Chen, Si-Ying Chen, Wei-June Chen, Ying-Ling Chen, Yi-Shin Weng, Hung-Li Wang. Neurochem Int 2010
60
40
H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
Hung-Li Wang, Su-Huei Hu, An-Hsun Chou, Shang-Seng Wang, Yi-Hsin Weng, Tu-Hsueh Yeh. Neuropharmacology 2013
Hung-Li Wang, Su-Huei Hu, An-Hsun Chou, Shang-Seng Wang, Yi-Hsin Weng, Tu-Hsueh Yeh. Neuropharmacology 2013
40
Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice.
Adebimpe W Kasumu, Xia Liang, Polina Egorova, Daria Vorontsova, Ilya Bezprozvanny. J Neurosci 2012
Adebimpe W Kasumu, Xia Liang, Polina Egorova, Daria Vorontsova, Ilya Bezprozvanny. J Neurosci 2012
40
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
40
Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice.
Edgardo Rodríguez-Lebrón, Maria do Carmo Costa, Katiuska Luna-Cancalon, Therese M Peron, Svetlana Fischer, Ryan L Boudreau, Beverly L Davidson, Henry L Paulson. Mol Ther 2013
Edgardo Rodríguez-Lebrón, Maria do Carmo Costa, Katiuska Luna-Cancalon, Therese M Peron, Svetlana Fischer, Ryan L Boudreau, Beverly L Davidson, Henry L Paulson. Mol Ther 2013
40
Enhancement of proteasome activity by a small-molecule inhibitor of USP14.
Byung-Hoon Lee, Min Jae Lee, Soyeon Park, Dong-Chan Oh, Suzanne Elsasser, Ping-Chung Chen, Carlos Gartner, Nevena Dimova, John Hanna, Steven P Gygi,[...]. Nature 2010
Byung-Hoon Lee, Min Jae Lee, Soyeon Park, Dong-Chan Oh, Suzanne Elsasser, Ping-Chung Chen, Carlos Gartner, Nevena Dimova, John Hanna, Steven P Gygi,[...]. Nature 2010
40
A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor.
Sonia K Pollitt, Judit Pallos, Jieya Shao, Urvee A Desai, Aye Aye K Ma, Leslie Michels Thompson, J Lawrence Marsh, Marc I Diamond. Neuron 2003
Sonia K Pollitt, Judit Pallos, Jieya Shao, Urvee A Desai, Aye Aye K Ma, Leslie Michels Thompson, J Lawrence Marsh, Marc I Diamond. Neuron 2003
40
Rapamycin alleviates toxicity of different aggregate-prone proteins.
Zdenek Berger, Brinda Ravikumar, Fiona M Menzies, Lourdes Garcia Oroz, Benjamin R Underwood, Menelas N Pangalos, Ina Schmitt, Ullrich Wullner, Bernd O Evert, Cahir J O'Kane,[...]. Hum Mol Genet 2006
Zdenek Berger, Brinda Ravikumar, Fiona M Menzies, Lourdes Garcia Oroz, Benjamin R Underwood, Menelas N Pangalos, Ina Schmitt, Ullrich Wullner, Bernd O Evert, Cahir J O'Kane,[...]. Hum Mol Genet 2006
40
Trehalose attenuates the gait ataxia and gliosis of spinocerebellar ataxia type 17 mice.
Zhi-Zhong Chen, Chien-Ming Wang, Guan-Chiun Lee, Ho-Chiang Hsu, Tzu-Ling Wu, Chia-Wei Lin, Chih-Kang Ma, Guey-Jen Lee-Chen, Hei-Jen Huang, Hsiu Mei Hsieh-Li. Neurochem Res 2015
Zhi-Zhong Chen, Chien-Ming Wang, Guan-Chiun Lee, Ho-Chiang Hsu, Tzu-Ling Wu, Chia-Wei Lin, Chih-Kang Ma, Guey-Jen Lee-Chen, Hei-Jen Huang, Hsiu Mei Hsieh-Li. Neurochem Res 2015
40
Tonic synaptic inhibition modulates neuronal output pattern and spatiotemporal synaptic integration.
M Häusser, B A Clark. Neuron 1997
M Häusser, B A Clark. Neuron 1997
40
Deranged calcium signaling in Purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias.
Adebimpe Kasumu, Ilya Bezprozvanny. Cerebellum 2012
Adebimpe Kasumu, Ilya Bezprozvanny. Cerebellum 2012
40
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Philipp Koch, Peter Breuer, Michael Peitz, Johannes Jungverdorben, Jaideep Kesavan, Daniel Poppe, Jonas Doerr, Julia Ladewig, Jerome Mertens, Thomas Tüting,[...]. Nature 2011
Philipp Koch, Peter Breuer, Michael Peitz, Johannes Jungverdorben, Jaideep Kesavan, Daniel Poppe, Jonas Doerr, Julia Ladewig, Jerome Mertens, Thomas Tüting,[...]. Nature 2011
40
BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.
Ying Ding, Hiroaki Adachi, Masahisa Katsuno, Kentaro Sahashi, Naohide Kondo, Madoka Iida, Genki Tohnai, Hideaki Nakatsuji, Gen Sobue. Neuroscience 2016
Ying Ding, Hiroaki Adachi, Masahisa Katsuno, Kentaro Sahashi, Naohide Kondo, Madoka Iida, Genki Tohnai, Hideaki Nakatsuji, Gen Sobue. Neuroscience 2016
40
Epigallocatechin-3-gallate and related phenol compounds redirect the amyloidogenic aggregation pathway of ataxin-3 towards non-toxic aggregates and prevent toxicity in neural cells and Caenorhabditis elegans animal model.
Cristina Visentin, Francesca Pellistri, Antonino Natalello, Jacopo Vertemara, Marcella Bonanomi, Elena Gatta, Amanda Penco, Annalisa Relini, Luca De Gioia, Cristina Airoldi,[...]. Hum Mol Genet 2017
Cristina Visentin, Francesca Pellistri, Antonino Natalello, Jacopo Vertemara, Marcella Bonanomi, Elena Gatta, Amanda Penco, Annalisa Relini, Luca De Gioia, Cristina Airoldi,[...]. Hum Mol Genet 2017
40
Suppression of Mutant Protein Expression in SCA3 and SCA1 Mice Using a CAG Repeat-Targeting Antisense Oligonucleotide.
Eleni Kourkouta, Rudie Weij, Anchel González-Barriga, Melissa Mulder, Ruurd Verheul, Sieto Bosgra, Bas Groenendaal, Jukka Puoliväli, Jussi Toivanen, Judith C T van Deutekom,[...]. Mol Ther Nucleic Acids 2019
Eleni Kourkouta, Rudie Weij, Anchel González-Barriga, Melissa Mulder, Ruurd Verheul, Sieto Bosgra, Bas Groenendaal, Jukka Puoliväli, Jussi Toivanen, Judith C T van Deutekom,[...]. Mol Ther Nucleic Acids 2019
40
Identifying Therapeutic Targets for Spinocerebellar Ataxia Type 3/Machado-Joseph Disease through Integration of Pathological Biomarkers and Therapeutic Strategies.
Yu-Shuan Chen, Zhen-Xiang Hong, Shinn-Zong Lin, Horng-Jyh Harn. Int J Mol Sci 2020
Yu-Shuan Chen, Zhen-Xiang Hong, Shinn-Zong Lin, Horng-Jyh Harn. Int J Mol Sci 2020
40
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
Jacqueline M Ward, Colleen A Stoyas, Pawel M Switonski, Farid Ichou, Weiwei Fan, Brett Collins, Christopher E Wall, Isaac Adanyeguh, Chenchen Niu, Bryce L Sopher,[...]. Cell Rep 2019
Jacqueline M Ward, Colleen A Stoyas, Pawel M Switonski, Farid Ichou, Weiwei Fan, Brett Collins, Christopher E Wall, Isaac Adanyeguh, Chenchen Niu, Bryce L Sopher,[...]. Cell Rep 2019
40
Effect of rovatirelin in patients with cerebellar ataxia: two randomised double-blind placebo-controlled phase 3 trials.
Masatoyo Nishizawa, Osamu Onodera, Akihiro Hirakawa, Yoshitaka Shimizu, Masayuki Yamada. J Neurol Neurosurg Psychiatry 2020
Masatoyo Nishizawa, Osamu Onodera, Akihiro Hirakawa, Yoshitaka Shimizu, Masayuki Yamada. J Neurol Neurosurg Psychiatry 2020
40
The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 mice.
Chiung-Mei Chen, Wan-Ling Chen, Chen-Ting Hung, Te-Hsien Lin, Chih-Ying Chao, Chih-Hsin Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Ching-Fa Yao, Guey-Jen Lee-Chen,[...]. Neurotoxicology 2018
Chiung-Mei Chen, Wan-Ling Chen, Chen-Ting Hung, Te-Hsien Lin, Chih-Ying Chao, Chih-Hsin Lin, Yih-Ru Wu, Kuo-Hsuan Chang, Ching-Fa Yao, Guey-Jen Lee-Chen,[...]. Neurotoxicology 2018
40
Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.
Eiko N Minakawa, Helena Akiko Popiel, Masayoshi Tada, Toshiaki Takahashi, Hiroshi Yamane, Yuji Saitoh, Yasuo Takahashi, Daisaku Ozawa, Akiko Takeda, Toshihide Takeuchi,[...]. Brain 2020
Eiko N Minakawa, Helena Akiko Popiel, Masayoshi Tada, Toshiaki Takahashi, Hiroshi Yamane, Yuji Saitoh, Yasuo Takahashi, Daisaku Ozawa, Akiko Takeda, Toshihide Takeuchi,[...]. Brain 2020
50
Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1.
Raphael Hourez, Laurent Servais, David Orduz, David Gall, Isabelle Millard, Alban de Kerchove d'Exaerde, Guy Cheron, Harry T Orr, Massimo Pandolfo, Serge N Schiffmann. J Neurosci 2011
Raphael Hourez, Laurent Servais, David Orduz, David Gall, Isabelle Millard, Alban de Kerchove d'Exaerde, Guy Cheron, Harry T Orr, Massimo Pandolfo, Serge N Schiffmann. J Neurosci 2011
40
Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.
Anabela Silva-Fernandes, Sara Duarte-Silva, Andreia Neves-Carvalho, Marina Amorim, Carina Soares-Cunha, Pedro Oliveira, Kenneth Thirstrup, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2014
Anabela Silva-Fernandes, Sara Duarte-Silva, Andreia Neves-Carvalho, Marina Amorim, Carina Soares-Cunha, Pedro Oliveira, Kenneth Thirstrup, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2014
40
A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
Daniel Goti, Scott M Katzen, Jesse Mez, Noam Kurtis, Jennifer Kiluk, Lea Ben-Haïem, Nancy A Jenkins, Neal G Copeland, Akira Kakizuka, Alan H Sharp,[...]. J Neurosci 2004
Daniel Goti, Scott M Katzen, Jesse Mez, Noam Kurtis, Jennifer Kiluk, Lea Ben-Haïem, Nancy A Jenkins, Neal G Copeland, Akira Kakizuka, Alan H Sharp,[...]. J Neurosci 2004
40
Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1.
M Cvetanovic, M Ingram, H Orr, P Opal. Neuroscience 2015
M Cvetanovic, M Ingram, H Orr, P Opal. Neuroscience 2015
40
Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism.
Hon Kit Wong, Peter O Bauer, Masaru Kurosawa, Anand Goswami, Chika Washizu, Yoko Machida, Asako Tosaki, Mizuki Yamada, Thomas Knöpfel, Takemichi Nakamura,[...]. Hum Mol Genet 2008
Hon Kit Wong, Peter O Bauer, Masaru Kurosawa, Anand Goswami, Chika Washizu, Yoko Machida, Asako Tosaki, Mizuki Yamada, Thomas Knöpfel, Takemichi Nakamura,[...]. Hum Mol Genet 2008
40
Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models.
Adriana Marcelo, Filipa Brito, Sara Carmo-Silva, Carlos A Matos, João Alves-Cruzeiro, Ana Vasconcelos-Ferreira, Rebekah Koppenol, Liliana Mendonça, Luís Pereira de Almeida, Clévio Nóbrega. Hum Mol Genet 2019
Adriana Marcelo, Filipa Brito, Sara Carmo-Silva, Carlos A Matos, João Alves-Cruzeiro, Ana Vasconcelos-Ferreira, Rebekah Koppenol, Liliana Mendonça, Luís Pereira de Almeida, Clévio Nóbrega. Hum Mol Genet 2019
40
Therapeutic Oligonucleotides: State of the Art.
C I Edvard Smith, Rula Zain. Annu Rev Pharmacol Toxicol 2019
C I Edvard Smith, Rula Zain. Annu Rev Pharmacol Toxicol 2019
40
Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
40
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Maxinne Watchon, Kristy C Yuan, Nick Mackovski, Adam J Svahn, Nicholas J Cole, Claire Goldsbury, Silke Rinkwitz, Thomas S Becker, Garth A Nicholson, Angela S Laird. J Neurosci 2017
Maxinne Watchon, Kristy C Yuan, Nick Mackovski, Adam J Svahn, Nicholas J Cole, Claire Goldsbury, Silke Rinkwitz, Thomas S Becker, Garth A Nicholson, Angela S Laird. J Neurosci 2017
40
Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.
Yasmin Fardghassemi, Arnaud Tauffenberger, Sarah Gosselin, J Alex Parker. Dis Model Mech 2017
Yasmin Fardghassemi, Arnaud Tauffenberger, Sarah Gosselin, J Alex Parker. Dis Model Mech 2017
40
Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model.
Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley,[...]. PLoS One 2017
Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley,[...]. PLoS One 2017
40
Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
Judit M Pérez Ortiz, Nissa Mollema, Nicholas Toker, Carolyn J Adamski, Brennon O'Callaghan, Lisa Duvick, Jillian Friedrich, Michael A Walters, Jessica Strasser, Jon E Hawkinson,[...]. Neurobiol Dis 2018
Judit M Pérez Ortiz, Nissa Mollema, Nicholas Toker, Carolyn J Adamski, Brennon O'Callaghan, Lisa Duvick, Jillian Friedrich, Michael A Walters, Jessica Strasser, Jon E Hawkinson,[...]. Neurobiol Dis 2018
40
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
Janghoo Lim, Juan Crespo-Barreto, Paymaan Jafar-Nejad, Aaron B Bowman, Ronald Richman, David E Hill, Harry T Orr, Huda Y Zoghbi. Nature 2008
Janghoo Lim, Juan Crespo-Barreto, Paymaan Jafar-Nejad, Aaron B Bowman, Ronald Richman, David E Hill, Harry T Orr, Huda Y Zoghbi. Nature 2008
40
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.