John D Hayes, Albena T Dinkova-Kostova, Kenneth D Tew. Cancer Cell 2020
Times Cited: 270
Times Cited: 270
Times Cited
Times Co-cited
Similarity
Modulation of oxidative stress as an anticancer strategy.
Chiara Gorrini, Isaac S Harris, Tak W Mak. Nat Rev Drug Discov 2013
Chiara Gorrini, Isaac S Harris, Tak W Mak. Nat Rev Drug Discov 2013
11
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
Dunyaporn Trachootham, Jerome Alexandre, Peng Huang. Nat Rev Drug Discov 2009
11
Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
Scott J Dixon, Kathryn M Lemberg, Michael R Lamprecht, Rachid Skouta, Eleina M Zaitsev, Caroline E Gleason, Darpan N Patel, Andras J Bauer, Alexandra M Cantley, Wan Seok Yang,[...]. Cell 2012
11
ROS signalling in the biology of cancer.
Jennifer N Moloney, Thomas G Cotter. Semin Cell Dev Biol 2018
Jennifer N Moloney, Thomas G Cotter. Semin Cell Dev Biol 2018
10
NRF2 and the Hallmarks of Cancer.
Montserrat Rojo de la Vega, Eli Chapman, Donna D Zhang. Cancer Cell 2018
Montserrat Rojo de la Vega, Eli Chapman, Donna D Zhang. Cancer Cell 2018
9
9
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.
Masayuki Yamamoto, Thomas W Kensler, Hozumi Motohashi. Physiol Rev 2018
Masayuki Yamamoto, Thomas W Kensler, Hozumi Motohashi. Physiol Rev 2018
9
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Helmut Sies, Dean P Jones. Nat Rev Mol Cell Biol 2020
Helmut Sies, Dean P Jones. Nat Rev Mol Cell Biol 2020
8
Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?
Simran S Sabharwal, Paul T Schumacker. Nat Rev Cancer 2014
Simran S Sabharwal, Paul T Schumacker. Nat Rev Cancer 2014
8
ROS function in redox signaling and oxidative stress.
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
7
ROS in cancer therapy: the bright side of the moon.
Bruno Perillo, Marzia Di Donato, Antonio Pezone, Erika Di Zazzo, Pia Giovannelli, Giovanni Galasso, Gabriella Castoria, Antimo Migliaccio. Exp Mol Med 2020
Bruno Perillo, Marzia Di Donato, Antonio Pezone, Erika Di Zazzo, Pia Giovannelli, Giovanni Galasso, Gabriella Castoria, Antimo Migliaccio. Exp Mol Med 2020
7
Regulation of ferroptotic cancer cell death by GPX4.
Wan Seok Yang, Rohitha SriRamaratnam, Matthew E Welsch, Kenichi Shimada, Rachid Skouta, Vasanthi S Viswanathan, Jaime H Cheah, Paul A Clemons, Alykhan F Shamji, Clary B Clish,[...]. Cell 2014
Wan Seok Yang, Rohitha SriRamaratnam, Matthew E Welsch, Kenichi Shimada, Rachid Skouta, Vasanthi S Viswanathan, Jaime H Cheah, Paul A Clemons, Alykhan F Shamji, Clary B Clish,[...]. Cell 2014
7
Activation of apoptosis signalling pathways by reactive oxygen species.
Maureen Redza-Dutordoir, Diana A Averill-Bates. Biochim Biophys Acta 2016
Maureen Redza-Dutordoir, Diana A Averill-Bates. Biochim Biophys Acta 2016
7
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
7
Crosstalk of reactive oxygen species and NF-κB signaling.
Michael J Morgan, Zheng-gang Liu. Cell Res 2011
Michael J Morgan, Zheng-gang Liu. Cell Res 2011
6
FSP1 is a glutathione-independent ferroptosis suppressor.
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Thamara Nishida Xavier da Silva, Elena Panzilius, Christina H Scheel,[...]. Nature 2019
Sebastian Doll, Florencio Porto Freitas, Ron Shah, Maceler Aldrovandi, Milene Costa da Silva, Irina Ingold, Andrea Goya Grocin, Thamara Nishida Xavier da Silva, Elena Panzilius, Christina H Scheel,[...]. Nature 2019
6
Reactive oxygen species and cancer paradox: To promote or to suppress?
Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy, Faisal Thayyullathil. Free Radic Biol Med 2017
Sehamuddin Galadari, Anees Rahman, Siraj Pallichankandy, Faisal Thayyullathil. Free Radic Biol Med 2017
6
Targeting the Thioredoxin System for Cancer Therapy.
Junmin Zhang, Xinming Li, Xiao Han, Ruijuan Liu, Jianguo Fang. Trends Pharmacol Sci 2017
Junmin Zhang, Xinming Li, Xiao Han, Ruijuan Liu, Jianguo Fang. Trends Pharmacol Sci 2017
6
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
Isaac S Harris, Aislinn E Treloar, Satoshi Inoue, Masato Sasaki, Chiara Gorrini, Kim Chung Lee, Ka Yi Yung, Dirk Brenner, Christiane B Knobbe-Thomsen, Maureen A Cox,[...]. Cancer Cell 2015
Isaac S Harris, Aislinn E Treloar, Satoshi Inoue, Masato Sasaki, Chiara Gorrini, Kim Chung Lee, Ka Yi Yung, Dirk Brenner, Christiane B Knobbe-Thomsen, Maureen A Cox,[...]. Cancer Cell 2015
6
Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
6
Oxidative stress, inflammation, and cancer: how are they linked?
Simone Reuter, Subash C Gupta, Madan M Chaturvedi, Bharat B Aggarwal. Free Radic Biol Med 2010
Simone Reuter, Subash C Gupta, Madan M Chaturvedi, Bharat B Aggarwal. Free Radic Biol Med 2010
6
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Kirill Bersuker, Joseph M Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H Tang, Melissa A Roberts, Bingqi Tong, Thomas J Maimone, Roberto Zoncu,[...]. Nature 2019
Kirill Bersuker, Joseph M Hendricks, Zhipeng Li, Leslie Magtanong, Breanna Ford, Peter H Tang, Melissa A Roberts, Bingqi Tong, Thomas J Maimone, Roberto Zoncu,[...]. Nature 2019
5
Targeting antioxidants for cancer therapy.
Andrea Glasauer, Navdeep S Chandel. Biochem Pharmacol 2014
Andrea Glasauer, Navdeep S Chandel. Biochem Pharmacol 2014
5
Ferroptosis as a p53-mediated activity during tumour suppression.
Le Jiang, Ning Kon, Tongyuan Li, Shang-Jui Wang, Tao Su, Hanina Hibshoosh, Richard Baer, Wei Gu. Nature 2015
Le Jiang, Ning Kon, Tongyuan Li, Shang-Jui Wang, Tao Su, Hanina Hibshoosh, Richard Baer, Wei Gu. Nature 2015
5
Hydrogen peroxide sensing, signaling and regulation of transcription factors.
H Susana Marinho, Carla Real, Luísa Cyrne, Helena Soares, Fernando Antunes. Redox Biol 2014
H Susana Marinho, Carla Real, Luísa Cyrne, Helena Soares, Fernando Antunes. Redox Biol 2014
5
Shikonin targets cytosolic thioredoxin reductase to induce ROS-mediated apoptosis in human promyelocytic leukemia HL-60 cells.
Dongzhu Duan, Baoxin Zhang, Juan Yao, Yaping Liu, Jianguo Fang. Free Radic Biol Med 2014
Dongzhu Duan, Baoxin Zhang, Juan Yao, Yaping Liu, Jianguo Fang. Free Radic Biol Med 2014
5
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.
Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher,[...]. Elife 2014
Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher,[...]. Elife 2014
5
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
Gina M DeNicola, Florian A Karreth, Timothy J Humpton, Aarthi Gopinathan, Cong Wei, Kristopher Frese, Dipti Mangal, Kenneth H Yu, Charles J Yeo, Eric S Calhoun,[...]. Nature 2011
Gina M DeNicola, Florian A Karreth, Timothy J Humpton, Aarthi Gopinathan, Cong Wei, Kristopher Frese, Dipti Mangal, Kenneth H Yu, Charles J Yeo, Eric S Calhoun,[...]. Nature 2011
5
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff, Brinton Seashore-Ludlow, Samuel D Kaffenberger, John K Eaton, Kenichi Shimada, Andrew J Aguirre,[...]. Nature 2017
Vasanthi S Viswanathan, Matthew J Ryan, Harshil D Dhruv, Shubhroz Gill, Ossia M Eichhoff, Brinton Seashore-Ludlow, Samuel D Kaffenberger, John K Eaton, Kenichi Shimada, Andrew J Aguirre,[...]. Nature 2017
5
Lymph protects metastasizing melanoma cells from ferroptosis.
Jessalyn M Ubellacker, Alpaslan Tasdogan, Vijayashree Ramesh, Bo Shen, Evann C Mitchell, Misty S Martin-Sandoval, Zhimin Gu, Michael L McCormick, Alison B Durham, Douglas R Spitz,[...]. Nature 2020
Jessalyn M Ubellacker, Alpaslan Tasdogan, Vijayashree Ramesh, Bo Shen, Evann C Mitchell, Misty S Martin-Sandoval, Zhimin Gu, Michael L McCormick, Alison B Durham, Douglas R Spitz,[...]. Nature 2020
5
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
5
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
Brent R Stockwell, José Pedro Friedmann Angeli, Hülya Bayir, Ashley I Bush, Marcus Conrad, Scott J Dixon, Simone Fulda, Sergio Gascón, Stavroula K Hatzios, Valerian E Kagan,[...]. Cell 2017
5
Cancer Statistics, 2021.
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
Rebecca L Siegel, Kimberly D Miller, Hannah E Fuchs, Ahmedin Jemal. CA Cancer J Clin 2021
5
Oxidative stress and cancer: an overview.
Venus Sosa, Teresa Moliné, Rosa Somoza, Rosanna Paciucci, Hiroshi Kondoh, Matilde E LLeonart. Ageing Res Rev 2013
Venus Sosa, Teresa Moliné, Rosa Somoza, Rosanna Paciucci, Hiroshi Kondoh, Matilde E LLeonart. Ageing Res Rev 2013
5
Promotion of HeLa cells apoptosis by cynaropicrin involving inhibition of thioredoxin reductase and induction of oxidative stress.
Tianyu Liu, Junmin Zhang, Xiao Han, Jianqiang Xu, Yueting Wu, Jianguo Fang. Free Radic Biol Med 2019
Tianyu Liu, Junmin Zhang, Xiao Han, Jianqiang Xu, Yueting Wu, Jianguo Fang. Free Radic Biol Med 2019
13
Small molecule inhibitors of mammalian thioredoxin reductase as potential anticancer agents: An update.
Junmin Zhang, Baoxin Zhang, Xinming Li, Xiao Han, Ruijuan Liu, Jianguo Fang. Med Res Rev 2019
Junmin Zhang, Baoxin Zhang, Xinming Li, Xiao Han, Ruijuan Liu, Jianguo Fang. Med Res Rev 2019
5
Antioxidants accelerate lung cancer progression in mice.
Volkan I Sayin, Mohamed X Ibrahim, Erik Larsson, Jonas A Nilsson, Per Lindahl, Martin O Bergo. Sci Transl Med 2014
Volkan I Sayin, Mohamed X Ibrahim, Erik Larsson, Jonas A Nilsson, Per Lindahl, Martin O Bergo. Sci Transl Med 2014
4
Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.
Dongzhu Duan, Junmin Zhang, Juan Yao, Yaping Liu, Jianguo Fang. J Biol Chem 2016
Dongzhu Duan, Junmin Zhang, Juan Yao, Yaping Liu, Jianguo Fang. J Biol Chem 2016
5
Superoxide dismutases: role in redox signaling, vascular function, and diseases.
Tohru Fukai, Masuko Ushio-Fukai. Antioxid Redox Signal 2011
Tohru Fukai, Masuko Ushio-Fukai. Antioxid Redox Signal 2011
4
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.
Antonio Cuadrado, Ana I Rojo, Geoffrey Wells, John D Hayes, Sharon P Cousin, William L Rumsey, Otis C Attucks, Stephen Franklin, Anna-Liisa Levonen, Thomas W Kensler,[...]. Nat Rev Drug Discov 2019
Antonio Cuadrado, Ana I Rojo, Geoffrey Wells, John D Hayes, Sharon P Cousin, William L Rumsey, Otis C Attucks, Stephen Franklin, Anna-Liisa Levonen, Thomas W Kensler,[...]. Nat Rev Drug Discov 2019
4
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch,[...]. Nat Chem Biol 2017
Sebastian Doll, Bettina Proneth, Yulia Y Tyurina, Elena Panzilius, Sho Kobayashi, Irina Ingold, Martin Irmler, Johannes Beckers, Michaela Aichler, Axel Walch,[...]. Nat Chem Biol 2017
4
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
4
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
William G Kaelin, Peter J Ratcliffe. Mol Cell 2008
William G Kaelin, Peter J Ratcliffe. Mol Cell 2008
4
Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose.
Yatao Du, Huihui Zhang, Jun Lu, Arne Holmgren. J Biol Chem 2012
Yatao Du, Huihui Zhang, Jun Lu, Arne Holmgren. J Biol Chem 2012
4
ROS homeostasis and metabolism: a dangerous liason in cancer cells.
E Panieri, M M Santoro. Cell Death Dis 2016
E Panieri, M M Santoro. Cell Death Dis 2016
4
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani, Tatsuhiro Shibata, Toshihiro Nukiwa, Hiroyuki Aburatani, Masayuki Yamamoto, Hozumi Motohashi. Cancer Cell 2012
Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani, Tatsuhiro Shibata, Toshihiro Nukiwa, Hiroyuki Aburatani, Masayuki Yamamoto, Hozumi Motohashi. Cancer Cell 2012
4
Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance.
Nobuaki Takahashi, Hsing-Yu Chen, Isaac S Harris, Daniel G Stover, Laura M Selfors, Roderick T Bronson, Thomas Deraedt, Karen Cichowski, Alana L Welm, Yasuo Mori,[...]. Cancer Cell 2018
Nobuaki Takahashi, Hsing-Yu Chen, Isaac S Harris, Daniel G Stover, Laura M Selfors, Roderick T Bronson, Thomas Deraedt, Karen Cichowski, Alana L Welm, Yasuo Mori,[...]. Cancer Cell 2018
4
Redox regulation of FoxO transcription factors.
Lars-Oliver Klotz, Cristina Sánchez-Ramos, Ignacio Prieto-Arroyo, Pavel Urbánek, Holger Steinbrenner, Maria Monsalve. Redox Biol 2015
Lars-Oliver Klotz, Cristina Sánchez-Ramos, Ignacio Prieto-Arroyo, Pavel Urbánek, Holger Steinbrenner, Maria Monsalve. Redox Biol 2015
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.