Alisdair McNeill, Emanuela Iovino, Luke Mansard, Christel Vache, David Baux, Emma Bedoukian, Helen Cox, John Dean, David Goudie, Ajith Kumar, Ruth Newbury-Ecob, Chiara Fallerini, Alessandra Renieri, Diego Lopergolo, Francesca Mari, Catherine Blanchet, Marjolaine Willems, Anne-Francoise Roux, Tommaso Pippucci, Eric Delpire. Brain 2020
Times Cited: 16
Times Cited: 16
Times Cited
Times Co-cited
Similarity
Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.
Hideki Mutai, Koichiro Wasano, Yukihide Momozawa, Yoichiro Kamatani, Fuyuki Miya, Sawako Masuda, Noriko Morimoto, Kiyomitsu Nara, Satoe Takahashi, Tatsuhiko Tsunoda,[...]. PLoS Genet 2020
Hideki Mutai, Koichiro Wasano, Yukihide Momozawa, Yoichiro Kamatani, Fuyuki Miya, Sawako Masuda, Noriko Morimoto, Kiyomitsu Nara, Satoe Takahashi, Tatsuhiko Tsunoda,[...]. PLoS Genet 2020
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Kilquist syndrome: A novel syndromic hearing loss disorder caused by homozygous deletion of SLC12A2.
Ellen F Macnamara, Alanna E Koehler, Precilla D'Souza, Tyra Estwick, Paul Lee, Gilbert Vezina, Harper Fauni, Stephen R Braddock, Erin Torti, James Matthew Holt,[...]. Hum Mutat 2019
Ellen F Macnamara, Alanna E Koehler, Precilla D'Souza, Tyra Estwick, Paul Lee, Gilbert Vezina, Harper Fauni, Stephen R Braddock, Erin Torti, James Matthew Holt,[...]. Hum Mutat 2019
56
Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
E Delpire, J Lu, R England, C Dull, T Thorne. Nat Genet 1999
E Delpire, J Lu, R England, C Dull, T Thorne. Nat Genet 1999
56
A patient with multisystem dysfunction carries a truncation mutation in human SLC12A2, the gene encoding the Na-K-2Cl cotransporter, NKCC1.
Eric Delpire, Lynne Wolfe, Bianca Flores, Rainelli Koumangoye, Cara C Schornak, Salma Omer, Barbara Pusey, Christopher Lau, Thomas Markello, David R Adams. Cold Spring Harb Mol Case Stud 2016
Eric Delpire, Lynne Wolfe, Bianca Flores, Rainelli Koumangoye, Cara C Schornak, Salma Omer, Barbara Pusey, Christopher Lau, Thomas Markello, David R Adams. Cold Spring Harb Mol Case Stud 2016
43
Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.
M Flagella, L L Clarke, M L Miller, L C Erway, R A Giannella, A Andringa, L R Gawenis, J Kramer, J J Duffy, T Doetschman,[...]. J Biol Chem 1999
M Flagella, L L Clarke, M L Miller, L C Erway, R A Giannella, A Andringa, L R Gawenis, J Kramer, J J Duffy, T Doetschman,[...]. J Biol Chem 1999
43
Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.
R L Evans, K Park, R J Turner, G E Watson, H V Nguyen, M R Dennett, A R Hand, M Flagella, G E Shull, J E Melvin. J Biol Chem 2000
R L Evans, K Park, R J Turner, G E Watson, H V Nguyen, M R Dennett, A R Hand, M Flagella, G E Shull, J E Melvin. J Biol Chem 2000
31
SLC12A2 mutations cause NKCC1 deficiency with encephalopathy and impaired secretory epithelia.
Tommy Stödberg, Måns Magnusson, Nicole Lesko, Anna Wredenberg, Daniel Martin Munoz, Henrik Stranneheim, Anna Wedell. Neurol Genet 2020
Tommy Stödberg, Måns Magnusson, Nicole Lesko, Anna Wredenberg, Daniel Martin Munoz, Henrik Stranneheim, Anna Wedell. Neurol Genet 2020
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Structure and mechanism of the cation-chloride cotransporter NKCC1.
Thomas A Chew, Benjamin J Orlando, Jinru Zhang, Naomi R Latorraca, Amy Wang, Scott A Hollingsworth, Dong-Hua Chen, Ron O Dror, Maofu Liao, Liang Feng. Nature 2019
Thomas A Chew, Benjamin J Orlando, Jinru Zhang, Naomi R Latorraca, Amy Wang, Scott A Hollingsworth, Dong-Hua Chen, Ron O Dror, Maofu Liao, Liang Feng. Nature 2019
25
Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter.
A J Pace, E Lee, K Athirakul, T M Coffman, D A O'Brien, B H Koller. J Clin Invest 2000
A J Pace, E Lee, K Athirakul, T M Coffman, D A O'Brien, B H Koller. J Clin Invest 2000
25
Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation.
Rainelli Koumangoye, Salma Omer, Mustafa H Kabeer, Eric Delpire. Cell Mol Gastroenterol Hepatol 2020
Rainelli Koumangoye, Salma Omer, Mustafa H Kabeer, Eric Delpire. Cell Mol Gastroenterol Hepatol 2020
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Mutation of the Na-K-Cl co-transporter gene Slc12a2 results in deafness in mice.
M J Dixon, J Gazzard, S S Chaudhry, N Sampson, B A Schulte, K P Steel. Hum Mol Genet 1999
M J Dixon, J Gazzard, S S Chaudhry, N Sampson, B A Schulte, K P Steel. Hum Mol Genet 1999
25
Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders.
Annalisa Savardi, Marco Borgogno, Roberto Narducci, Giuseppina La Sala, Jose Antonio Ortega, Maria Summa, Andrea Armirotti, Rosalia Bertorelli, Andrea Contestabile, Marco De Vivo,[...]. Chem 2020
Annalisa Savardi, Marco Borgogno, Roberto Narducci, Giuseppina La Sala, Jose Antonio Ortega, Maria Summa, Andrea Armirotti, Rosalia Bertorelli, Andrea Contestabile, Marco De Vivo,[...]. Chem 2020
25
Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
K W Sung, M Kirby, M P McDonald, D M Lovinger, E Delpire. J Neurosci 2000
K W Sung, M Kirby, M P McDonald, D M Lovinger, E Delpire. J Neurosci 2000
25
Na+ -K+ -2Cl- Cotransporter (NKCC) Physiological Function in Nonpolarized Cells and Transporting Epithelia.
Eric Delpire, Kenneth B Gagnon. Compr Physiol 2018
Eric Delpire, Kenneth B Gagnon. Compr Physiol 2018
18
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation.
C Rivera, J Voipio, J A Payne, E Ruusuvuori, H Lahtinen, K Lamsa, U Pirvola, M Saarma, K Kaila. Nature 1999
C Rivera, J Voipio, J A Payne, E Ruusuvuori, H Lahtinen, K Lamsa, U Pirvola, M Saarma, K Kaila. Nature 1999
18
Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring.
Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal,[...]. Science 2014
Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal,[...]. Science 2014
18
Presynaptic inhibition and spinal pain processing in mice: a possible role of the NKCC1 cation-chloride co-transporter in hyperalgesia.
Jennifer M A Laird, Esther García-Nicas, Eric J Delpire, Fernando Cervero. Neurosci Lett 2004
Jennifer M A Laird, Esther García-Nicas, Eric J Delpire, Fernando Cervero. Neurosci Lett 2004
18
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.
Gerardo Gamba. Physiol Rev 2005
Gerardo Gamba. Physiol Rev 2005
18
Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Si Liu, Shenghai Chang, Binming Han, Lingyi Xu, Mingfeng Zhang, Cheng Zhao, Wei Yang, Feng Wang, Jingyuan Li, Eric Delpire,[...]. Science 2019
Si Liu, Shenghai Chang, Binming Han, Lingyi Xu, Mingfeng Zhang, Cheng Zhao, Wei Yang, Feng Wang, Jingyuan Li, Eric Delpire,[...]. Science 2019
18
Intestinal ion transport in NKCC1-deficient mice.
B R Grubb, E Lee, A J Pace, B H Koller, R C Boucher. Am J Physiol Gastrointest Liver Physiol 2000
B R Grubb, E Lee, A J Pace, B H Koller, R C Boucher. Am J Physiol Gastrointest Liver Physiol 2000
18
Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs.
Michelle S Reid, David M Kern, Stephen Graf Brohawn. Elife 2020
Michelle S Reid, David M Kern, Stephen Graf Brohawn. Elife 2020
18
Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.
Kenneth B Gagnon, Eric Delpire. Am J Physiol Cell Physiol 2013
Kenneth B Gagnon, Eric Delpire. Am J Physiol Cell Physiol 2013
18
Water Homeostasis and Cell Volume Maintenance and Regulation.
Eric Delpire, Kenneth B Gagnon. Curr Top Membr 2018
Eric Delpire, Kenneth B Gagnon. Curr Top Membr 2018
18
Structures and an activation mechanism of human potassium-chloride cotransporters.
Yuan Xie, Shenghai Chang, Cheng Zhao, Feng Wang, Si Liu, Jin Wang, Eric Delpire, Sheng Ye, Jiangtao Guo. Sci Adv 2020
Yuan Xie, Shenghai Chang, Cheng Zhao, Feng Wang, Si Liu, Jin Wang, Eric Delpire, Sheng Ye, Jiangtao Guo. Sci Adv 2020
27
Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride.
Lei Zhu, David Lovinger, Eric Delpire. J Neurophysiol 2005
Lei Zhu, David Lovinger, Eric Delpire. J Neurophysiol 2005
18
NKCC1 transporter facilitates seizures in the developing brain.
Volodymyr I Dzhala, Delia M Talos, Dan A Sdrulla, Audrey C Brumback, Gregory C Mathews, Timothy A Benke, Eric Delpire, Frances E Jensen, Kevin J Staley. Nat Med 2005
Volodymyr I Dzhala, Delia M Talos, Dan A Sdrulla, Audrey C Brumback, Gregory C Mathews, Timothy A Benke, Eric Delpire, Frances E Jensen, Kevin J Staley. Nat Med 2005
18
Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Justin S A Perry, Sho Morioka, Christopher B Medina, J Iker Etchegaray, Brady Barron, Michael H Raymond, Christopher D Lucas, Suna Onengut-Gumuscu, Eric Delpire, Kodi S Ravichandran. Nat Cell Biol 2019
Justin S A Perry, Sho Morioka, Christopher B Medina, J Iker Etchegaray, Brady Barron, Michael H Raymond, Christopher D Lucas, Suna Onengut-Gumuscu, Eric Delpire, Kodi S Ravichandran. Nat Cell Biol 2019
18
Alterations in airway ion transport in NKCC1-deficient mice.
B R Grubb, A J Pace, E Lee, B H Koller, R C Boucher. Am J Physiol Cell Physiol 2001
B R Grubb, A J Pace, E Lee, B H Koller, R C Boucher. Am J Physiol Cell Physiol 2001
18
A randomised controlled trial of bumetanide in the treatment of autism in children.
E Lemonnier, C Degrez, M Phelep, R Tyzio, F Josse, M Grandgeorge, N Hadjikhani, Y Ben-Ari. Transl Psychiatry 2012
E Lemonnier, C Degrez, M Phelep, R Tyzio, F Josse, M Grandgeorge, N Hadjikhani, Y Ben-Ari. Transl Psychiatry 2012
18
Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia.
Nancy D Merner, Adriana Mercado, Arjun R Khanna, Alan Hodgkinson, Vanessa Bruat, Philip Awadalla, Gerardo Gamba, Guy A Rouleau, Kristopher T Kahle. J Psychiatr Res 2016
Nancy D Merner, Adriana Mercado, Arjun R Khanna, Alan Hodgkinson, Vanessa Bruat, Philip Awadalla, Gerardo Gamba, Guy A Rouleau, Kristopher T Kahle. J Psychiatr Res 2016
18
Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.
G Gamba, A Miyanoshita, M Lombardi, J Lytton, W S Lee, M A Hediger, S C Hebert. J Biol Chem 1994
G Gamba, A Miyanoshita, M Lombardi, J Lytton, W S Lee, M A Hediger, S C Hebert. J Biol Chem 1994
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Uncompensated polyuria in a mouse model of Bartter's syndrome.
N Takahashi, D R Chernavvsky, R A Gomez, P Igarashi, H J Gitelman, O Smithies. Proc Natl Acad Sci U S A 2000
N Takahashi, D R Chernavvsky, R A Gomez, P Igarashi, H J Gitelman, O Smithies. Proc Natl Acad Sci U S A 2000
18
A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.
Rachel B Darman, Biff Forbush. J Biol Chem 2002
Rachel B Darman, Biff Forbush. J Biol Chem 2002
12
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
Kerstin Piechotta, Jianming Lu, Eric Delpire. J Biol Chem 2002
Kerstin Piechotta, Jianming Lu, Eric Delpire. J Biol Chem 2002
12
Bumetanide: potent new "loop" diuretic.
M J Asbury, P B Gatenby, S O'Sullivan, E Bourke. Br Med J 1972
M J Asbury, P B Gatenby, S O'Sullivan, E Bourke. Br Med J 1972
12
Riding the tides: K+ concentration and volume regulation by muscle Na+-K+-2Cl- cotransport activity.
Aidar R Gosmanov, Michael I Lindinger, Donald B Thomason. News Physiol Sci 2003
Aidar R Gosmanov, Michael I Lindinger, Donald B Thomason. News Physiol Sci 2003
12
Outward chloride/cation co-transport in mammalian cortical neurons.
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12
Age-related change in the expression of NKCC1 in the cochlear lateral wall of C57BL/6J mice.
Yun Liu, Hanqi Chu, Jin Chen, Liangqiang Zhou, Qingguo Chen, Yang Yu, Zhengong Wu, Shaoli Wang, Yanbing Lai, Chunchen Pan,[...]. Acta Otolaryngol 2014
Yun Liu, Hanqi Chu, Jin Chen, Liangqiang Zhou, Qingguo Chen, Yang Yu, Zhengong Wu, Shaoli Wang, Yanbing Lai, Chunchen Pan,[...]. Acta Otolaryngol 2014
22
Modulation of ion transport by direct targeting of protein phosphatase type 1 to the Na-K-Cl cotransporter.
R B Darman, A Flemmer, B Forbush. J Biol Chem 2001
R B Darman, A Flemmer, B Forbush. J Biol Chem 2001
12
Targeted Gene Resequencing (Astrochip) to Explore the Tripartite Synapse in Autism-Epilepsy Phenotype with Macrocephaly.
Maria Marchese, Giulia Valvo, Francesca Moro, Federico Sicca, Filippo M Santorelli. Neuromolecular Med 2016
Maria Marchese, Giulia Valvo, Francesca Moro, Federico Sicca, Filippo M Santorelli. Neuromolecular Med 2016
15
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
Alberto C Vitari, Jacob Thastrup, Fatema H Rafiqi, Maria Deak, Nick A Morrice, Håkan K R Karlsson, Dario R Alessi. Biochem J 2006
Alberto C Vitari, Jacob Thastrup, Fatema H Rafiqi, Maria Deak, Nick A Morrice, Håkan K R Karlsson, Dario R Alessi. Biochem J 2006
12
Hypotension in NKCC1 null mice: role of the kidneys.
Susan M Wall, Mark A Knepper, Kathryn A Hassell, Michael P Fischer, Adetola Shodeinde, Wonkyong Shin, Truyen Derek Pham, Jamie W Meyer, John N Lorenz, William H Beierwaltes,[...]. Am J Physiol Renal Physiol 2006
Susan M Wall, Mark A Knepper, Kathryn A Hassell, Michael P Fischer, Adetola Shodeinde, Wonkyong Shin, Truyen Derek Pham, Jamie W Meyer, John N Lorenz, William H Beierwaltes,[...]. Am J Physiol Renal Physiol 2006
12
Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain.
M D Plotkin, E Y Snyder, S C Hebert, E Delpire. J Neurobiol 1997
M D Plotkin, E Y Snyder, S C Hebert, E Delpire. J Neurobiol 1997
12
Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter.
Jamie W Meyer, Michael Flagella, Roy L Sutliff, John N Lorenz, Michelle L Nieman, Craig S Weber, Richard J Paul, Gary E Shull. Am J Physiol Heart Circ Physiol 2002
Jamie W Meyer, Michael Flagella, Roy L Sutliff, John N Lorenz, Michelle L Nieman, Craig S Weber, Richard J Paul, Gary E Shull. Am J Physiol Heart Circ Physiol 2002
12
Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.
Kenneth B E Gagnon, Roger England, Eric Delpire. Am J Physiol Cell Physiol 2006
Kenneth B E Gagnon, Roger England, Eric Delpire. Am J Physiol Cell Physiol 2006
12
Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells.
Rainelli Koumangoye, Salma Omer, Eric Delpire. Am J Physiol Cell Physiol 2018
Rainelli Koumangoye, Salma Omer, Eric Delpire. Am J Physiol Cell Physiol 2018
18
Ultrastructure of the inner ear of NKCC1-deficient mice.
A J Pace, V J Madden, O W Henson, B H Koller, M M Henson. Hear Res 2001
A J Pace, V J Madden, O W Henson, B H Koller, M M Henson. Hear Res 2001
12
Cotransporter-mediated water transport underlying cerebrospinal fluid formation.
Annette B Steffensen, Eva K Oernbo, Anca Stoica, Niklas J Gerkau, Dagne Barbuskaite, Katerina Tritsaris, Christine R Rose, Nanna MacAulay. Nat Commun 2018
Annette B Steffensen, Eva K Oernbo, Anca Stoica, Niklas J Gerkau, Dagne Barbuskaite, Katerina Tritsaris, Christine R Rose, Nanna MacAulay. Nat Commun 2018
12
Intracellular chloride regulation in amphibian dorsal root ganglion neurones studied with ion-selective microelectrodes.
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The diuretic bumetanide decreases autistic behaviour in five infants treated during 3 months with no side effects.
Eric Lemonnier, Yehezkel Ben-Ari. Acta Paediatr 2010
Eric Lemonnier, Yehezkel Ben-Ari. Acta Paediatr 2010
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.