Kevin A Guttenplan, Maya K Weigel, Drew I Adler, Julien Couthouis, Shane A Liddelow, Aaron D Gitler, Ben A Barres. Nat Commun 2020
Times Cited: 49
Times Cited: 49
Times Cited
Times Co-cited
Similarity
Neurotoxic reactive astrocytes are induced by activated microglia.
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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
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Normal aging induces A1-like astrocyte reactivity.
Laura E Clarke, Shane A Liddelow, Chandrani Chakraborty, Alexandra E Münch, Myriam Heiman, Ben A Barres. Proc Natl Acad Sci U S A 2018
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Genomic analysis of reactive astrogliosis.
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Onset and progression in inherited ALS determined by motor neurons and microglia.
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
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Reactive astrocyte nomenclature, definitions, and future directions.
Carole Escartin, Elena Galea, András Lakatos, James P O'Callaghan, Gabor C Petzold, Alberto Serrano-Pozo, Christian Steinhäuser, Andrea Volterra, Giorgio Carmignoto, Amit Agarwal,[...]. Nat Neurosci 2021
Carole Escartin, Elena Galea, András Lakatos, James P O'Callaghan, Gabor C Petzold, Alberto Serrano-Pozo, Christian Steinhäuser, Andrea Volterra, Giorgio Carmignoto, Amit Agarwal,[...]. Nat Neurosci 2021
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An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.
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The multi-dimensional roles of astrocytes in ALS.
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Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model.
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Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity.
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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.
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A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models.
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Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
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A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
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The classical complement cascade mediates CNS synapse elimination.
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Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease.
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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
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Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo.
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14
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
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14
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS.
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14
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
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12
Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury.
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Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse.
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Astrocyte scar formation aids central nervous system axon regeneration.
Mark A Anderson, Joshua E Burda, Yilong Ren, Yan Ao, Timothy M O'Shea, Riki Kawaguchi, Giovanni Coppola, Baljit S Khakh, Timothy J Deming, Michael V Sofroniew. Nature 2016
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Oligodendroglia metabolically support axons and contribute to neurodegeneration.
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Shin H Kang, Ying Li, Masahiro Fukaya, Ileana Lorenzini, Don W Cleveland, Lyle W Ostrow, Jeffrey D Rothstein, Dwight E Bergles. Nat Neurosci 2013
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C9orf72 is required for proper macrophage and microglial function in mice.
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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
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STAR: ultrafast universal RNA-seq aligner.
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Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.
Amit U Joshi, Paras S Minhas, Shane A Liddelow, Bereketeab Haileselassie, Katrin I Andreasson, Gerald W Dorn, Daria Mochly-Rosen. Nat Neurosci 2019
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12
Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism.
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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
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Astrocyte molecular signatures in Huntington's disease.
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Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
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Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.