Ajinkya S Kawale, Patrick Sung. Essays Biochem 2020
Times Cited: 6
Times Cited: 6
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Perfecting DNA double-strand break repair on transcribed chromatin.
Xin Yi Tan, Michael S Y Huen. Essays Biochem 2020
Xin Yi Tan, Michael S Y Huen. Essays Biochem 2020
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Making it or breaking it: DNA methylation and genome integrity.
Anusha Sriraman, Turja K Debnath, Blerta Xhemalce, Kyle M Miller. Essays Biochem 2020
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Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair.
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Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1.
Hai Dang Nguyen, Tribhuwan Yadav, Sumanprava Giri, Borja Saez, Timothy A Graubert, Lee Zou. Mol Cell 2017
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Novel RNA and DNA strand exchange activity of the PALB2 DNA binding domain and its critical role for DNA repair in cells.
Jaigeeth Deveryshetty, Thibaut Peterlini, Mikhail Ryzhikov, Nadine Brahiti, Graham Dellaire, Jean-Yves Masson, Sergey Korolev. Elife 2019
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Replication protein A binds RNA and promotes R-loop formation.
Olga M Mazina, Srinivas Somarowthu, Lyudmila Y Kadyrova, Andrey G Baranovskiy, Tahir H Tahirov, Farid A Kadyrov, Alexander V Mazin. J Biol Chem 2020
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Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
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Dynamics and selective remodeling of the DNA-binding domains of RPA.
Nilisha Pokhrel, Colleen C Caldwell, Elliot I Corless, Emma A Tillison, Joseph Tibbs, Nina Jocic, S M Ali Tabei, Marc S Wold, Maria Spies, Edwin Antony. Nat Struct Mol Biol 2019
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Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins.
Rohit Prakash, Yu Zhang, Weiran Feng, Maria Jasin. Cold Spring Harb Perspect Biol 2015
Rohit Prakash, Yu Zhang, Weiran Feng, Maria Jasin. Cold Spring Harb Perspect Biol 2015
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DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
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Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
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m5C modification of mRNA serves a DNA damage code to promote homologous recombination.
Hao Chen, Haibo Yang, Xiaolan Zhu, Tribhuwan Yadav, Jian Ouyang, Samuel S Truesdell, Jun Tan, Yumin Wang, Meihan Duan, Leizhen Wei,[...]. Nat Commun 2020
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Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes.
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PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Rimma Belotserkovskaya, Elisenda Raga Gil, Nicola Lawrence, Richard Butler, Gillian Clifford, Marcus D Wilson, Stephen P Jackson. Nat Commun 2020
Rimma Belotserkovskaya, Elisenda Raga Gil, Nicola Lawrence, Richard Butler, Gillian Clifford, Marcus D Wilson, Stephen P Jackson. Nat Commun 2020
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Alerting the immune system to DNA damage: micronuclei as mediators.
Kate M MacDonald, Soraya Benguerfi, Shane M Harding. Essays Biochem 2020
Kate M MacDonald, Soraya Benguerfi, Shane M Harding. Essays Biochem 2020
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Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining.
Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L Blundell, Amanda K Chaplin. Essays Biochem 2020
Antonia Kefala Stavridi, Robert Appleby, Shikang Liang, Tom L Blundell, Amanda K Chaplin. Essays Biochem 2020
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Jack of all trades? The versatility of RNA in DNA double-strand break repair.
Ruth F Ketley, Monika Gullerova. Essays Biochem 2020
Ruth F Ketley, Monika Gullerova. Essays Biochem 2020
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The role of DNA damage response in amyotrophic lateral sclerosis.
Yu Sun, Annabel J Curle, Arshad M Haider, Gabriel Balmus. Essays Biochem 2020
Yu Sun, Annabel J Curle, Arshad M Haider, Gabriel Balmus. Essays Biochem 2020
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Ubiquitin-like proteins in the DNA damage response: the next generation.
Isabelle C Da Costa, Christine K Schmidt. Essays Biochem 2020
Isabelle C Da Costa, Christine K Schmidt. Essays Biochem 2020
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RecQ helicases in DNA repair and cancer targets.
Joseph A Newman, Opher Gileadi. Essays Biochem 2020
Joseph A Newman, Opher Gileadi. Essays Biochem 2020
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Structural insight into FANCI-FANCD2 monoubiquitination.
Landing Li, Winnie Tan, Andrew J Deans. Essays Biochem 2020
Landing Li, Winnie Tan, Andrew J Deans. Essays Biochem 2020
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Base excision repair and its implications to cancer therapy.
Gabrielle J Grundy, Jason L Parsons. Essays Biochem 2020
Gabrielle J Grundy, Jason L Parsons. Essays Biochem 2020
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Regulation of the MLH1-MLH3 endonuclease in meiosis.
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The double-strand-break repair model for recombination.
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The Cdk/cDc14 module controls activation of the Yen1 holliday junction resolvase to promote genome stability.
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PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair.
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Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1.
Nicolas Bocquet, Anna H Bizard, Wassim Abdulrahman, Nicolai B Larsen, Mahamadou Faty, Simone Cavadini, Richard D Bunker, Stephen C Kowalczykowski, Petr Cejka, Ian D Hickson,[...]. Nat Struct Mol Biol 2014
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Unresolved Recombination Intermediates Cause a RAD9-Dependent Cell Cycle Arrest in Saccharomyces cerevisiae.
Hardeep Kaur, Krishnaprasad Gn, Michael Lichten. Genetics 2019
Hardeep Kaur, Krishnaprasad Gn, Michael Lichten. Genetics 2019
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A point mutation in the nuclease domain of MLH3 eliminates repeat expansions in a mouse stem cell model of the Fragile X-related disorders.
Bruce E Hayward, Peter J Steinbach, Karen Usdin. Nucleic Acids Res 2020
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Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity.
Anja Waizenegger, Madhusoodanan Urulangodi, Carl P Lehmann, Teresa Anne Clarisse Reyes, Irene Saugar, José Antonio Tercero, Barnabas Szakal, Dana Branzei. Nat Commun 2020
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Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease.
Maria V Rogacheva, Carol M Manhart, Cheng Chen, Alba Guarne, Jennifer Surtees, Eric Alani. J Biol Chem 2014
Maria V Rogacheva, Carol M Manhart, Cheng Chen, Alba Guarne, Jennifer Surtees, Eric Alani. J Biol Chem 2014
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Implications of Metastable Nicks and Nicked Holliday Junctions in Processing Joint Molecules in Mitosis and Meiosis.
Félix Machín. Genes (Basel) 2020
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Holliday junction resolution: regulation in space and time.
Joao Matos, Stephen C West. DNA Repair (Amst) 2014
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A loss-of-function variant in DNA mismatch repair gene MLH3 underlies severe oligozoospermia.
Shoaib Nawaz, Muhammad Imran Ullah, Beenish Samreen Hamid, Jalwa Nargis, Mehboob Nawaz, Shabir Hussain, Wasim Ahmad. J Hum Genet 2021
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PCNA activates the MutLγ endonuclease to promote meiotic crossing over.
Dhananjaya S Kulkarni, Shannon N Owens, Masayoshi Honda, Masaru Ito, Ye Yang, Mary W Corrigan, Lan Chen, Aric L Quan, Neil Hunter. Nature 2020
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Top3-Rmi1 DNA single-strand decatenase is integral to the formation and resolution of meiotic recombination intermediates.
Hardeep Kaur, Arnaud De Muyt, Michael Lichten. Mol Cell 2015
Hardeep Kaur, Arnaud De Muyt, Michael Lichten. Mol Cell 2015
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Genetic Evidence for the Involvement of Mismatch Repair Proteins, PMS2 and MLH3, in a Late Step of Homologous Recombination.
Md Maminur Rahman, Mohiuddin Mohiuddin, Islam Shamima Keka, Kousei Yamada, Masataka Tsuda, Hiroyuki Sasanuma, Jessica Andreani, Raphael Guerois, Valérie Borde, Jean-Baptiste Charbonnier,[...]. J Biol Chem 2020
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Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability.
Miguel G Blanco, Joao Matos, Stephen C West. Mol Cell 2014
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MutSβ Stimulates Holliday Junction Resolution by the SMX Complex.
Sarah J Young, Marie Sebald, Rajvee Shah Punatar, Meghan Larin, Laura Masino, Monica C Rodrigo-Brenni, Chih-Chao Liang, Stephen C West. Cell Rep 2020
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TopBP1 controls BLM protein level to maintain genome stability.
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Identification of Holliday junction resolvases from humans and yeast.
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Distributing meiotic crossovers for optimal fertility and evolution.
Mridula Nambiar, Yu-Chien Chuang, Gerald R Smith. DNA Repair (Amst) 2019
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A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I.
Melissa Toledo, Xianfei Sun, Miguel A Brieño-Enríquez, Vandana Raghavan, Stephen Gray, Jeffrey Pea, Carolyn R Milano, Anita Venkatesh, Lekha Patel, Peter L Borst,[...]. PLoS Genet 2019
Melissa Toledo, Xianfei Sun, Miguel A Brieño-Enríquez, Vandana Raghavan, Stephen Gray, Jeffrey Pea, Carolyn R Milano, Anita Venkatesh, Lekha Patel, Peter L Borst,[...]. PLoS Genet 2019
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Endonucleolytic function of MutLalpha in human mismatch repair.
Farid A Kadyrov, Leonid Dzantiev, Nicoleta Constantin, Paul Modrich. Cell 2006
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Phosphorylation of the RecQ Helicase Sgs1/BLM Controls Its DNA Unwinding Activity during Meiosis and Mitosis.
Rokas Grigaitis, Lepakshi Ranjha, Philipp Wild, Kristina Kasaciunaite, Ilaria Ceppi, Vera Kissling, Adrian Henggeler, Aitor Susperregui, Matthias Peter, Ralf Seidel,[...]. Dev Cell 2020
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The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions.
Lepakshi Ranjha, Roopesh Anand, Petr Cejka. J Biol Chem 2014
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The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.
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