A citation-based method for searching scientific literature

Thomas C Roberts, Robert Langer, Matthew J A Wood. Nat Rev Drug Discov 2020
Times Cited: 328







List of co-cited articles
824 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.
A Fire, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello. Nature 1998
12

RNA-Targeted Therapeutics.
Stanley T Crooke, Joseph L Witztum, C Frank Bennett, Brenda F Baker. Cell Metab 2018
302
12

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.
David Adams, Alejandra Gonzalez-Duarte, William D O'Riordan, Chih-Chao Yang, Mitsuharu Ueda, Arnt V Kristen, Ivailo Tournev, Hartmut H Schmidt, Teresa Coelho, John L Berk,[...]. N Engl J Med 2018
10

The current state and future directions of RNAi-based therapeutics.
Ryan L Setten, John J Rossi, Si-Ping Han. Nat Rev Drug Discov 2019
414
10


Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
Manisha Balwani, Eliane Sardh, Paolo Ventura, Paula Aguilera Peiró, David C Rees, Ulrich Stölzel, D Montgomery Bissell, Herbert L Bonkovsky, Jerzy Windyga, Karl E Anderson,[...]. N Engl J Med 2020
131
9


The chemical evolution of oligonucleotide therapies of clinical utility.
Anastasia Khvorova, Jonathan K Watts. Nat Biotechnol 2017
439
9

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine.
Fernando P Polack, Stephen J Thomas, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, John L Perez, Gonzalo Pérez Marc, Edson D Moreira, Cristiano Zerbini,[...]. N Engl J Med 2020
9

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.
S M Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl. Nature 2001
9

Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing.
Jayaprakash K Nair, Jennifer L S Willoughby, Amy Chan, Klaus Charisse, Md Rowshon Alam, Qianfan Wang, Menno Hoekstra, Pachamuthu Kandasamy, Alexander V Kel'in, Stuart Milstein,[...]. J Am Chem Soc 2014
504
8


Lumasiran: First Approval.
Lesley J Scott, Susan J Keam. Drugs 2021
45
17

Therapeutic siRNA: state of the art.
Bo Hu, Liping Zhong, Yuhua Weng, Ling Peng, Yuanyu Huang, Yongxiang Zhao, Xing-Jie Liang. Signal Transduct Target Ther 2020
171
8

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Lindsey R Baden, Hana M El Sahly, Brandon Essink, Karen Kotloff, Sharon Frey, Rick Novak, David Diemert, Stephen A Spector, Nadine Rouphael, C Buddy Creech,[...]. N Engl J Med 2021
8

GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics.
Aaron D Springer, Steven F Dowdy. Nucleic Acid Ther 2018
168
8


The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Akin Akinc, Martin A Maier, Muthiah Manoharan, Kevin Fitzgerald, Muthusamy Jayaraman, Scott Barros, Steven Ansell, Xinyao Du, Michael J Hope, Thomas D Madden,[...]. Nat Nanotechnol 2019
253
8

The current landscape of nucleic acid therapeutics.
Jayesh A Kulkarni, Dominik Witzigmann, Sarah B Thomson, Sam Chen, Blair R Leavitt, Pieter R Cullis, Roy van der Meel. Nat Nanotechnol 2021
48
16

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.
Thazha P Prakash, Mark J Graham, Jinghua Yu, Rick Carty, Audrey Low, Alfred Chappell, Karsten Schmidt, Chenguang Zhao, Mariam Aghajan, Heather F Murray,[...]. Nucleic Acids Res 2014
294
8

Aptamers as targeted therapeutics: current potential and challenges.
Jiehua Zhou, John Rossi. Nat Rev Drug Discov 2017
646
8

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.
Richard S Finkel, Eugenio Mercuri, Basil T Darras, Anne M Connolly, Nancy L Kuntz, Janbernd Kirschner, Claudia A Chiriboga, Kayoko Saito, Laurent Servais, Eduardo Tizzano,[...]. N Engl J Med 2017
849
7

Givosiran: First Approval.
Lesley J Scott. Drugs 2020
117
7

mRNA vaccines - a new era in vaccinology.
Norbert Pardi, Michael J Hogan, Frederick W Porter, Drew Weissman. Nat Rev Drug Discov 2018
7

The delivery of therapeutic oligonucleotides.
Rudolph L Juliano. Nucleic Acids Res 2016
440
7


Patisiran: First Global Approval.
Sheridan M Hoy. Drugs 2018
202
7

Overcoming cellular barriers for RNA therapeutics.
Steven F Dowdy. Nat Biotechnol 2017
428
7

Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides.
Richard S Geary, Daniel Norris, Rosie Yu, C Frank Bennett. Adv Drug Deliv Rev 2015
420
7

Engineering precision nanoparticles for drug delivery.
Michael J Mitchell, Margaret M Billingsley, Rebecca M Haley, Marissa E Wechsler, Nicholas A Peppas, Robert Langer. Nat Rev Drug Discov 2021
486
7

Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease.
Jinkuk Kim, Chunguang Hu, Christelle Moufawad El Achkar, Lauren E Black, Julie Douville, Austin Larson, Mary K Pendergast, Sara F Goldkind, Eunjung A Lee, Ashley Kuniholm,[...]. N Engl J Med 2019
211
7

Molecular Mechanisms of Antisense Oligonucleotides.
Stanley T Crooke. Nucleic Acid Ther 2017
147
7

Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development.
Karishma Dhuri, Clara Bechtold, Elias Quijano, Ha Pham, Anisha Gupta, Ajit Vikram, Raman Bahal. J Clin Med 2020
58
10

Impact of enhanced metabolic stability on pharmacokinetics and pharmacodynamics of GalNAc-siRNA conjugates.
Jayaprakash K Nair, Husain Attarwala, Alfica Sehgal, Qianfan Wang, Krishna Aluri, Xuemei Zhang, Minggeng Gao, Ju Liu, Ramesh Indrakanti, Sally Schofield,[...]. Nucleic Acids Res 2017
100
6


Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
Naoki Iwamoto, David C D Butler, Nenad Svrzikapa, Susovan Mohapatra, Ivan Zlatev, Dinah W Y Sah, Meena, Stephany M Standley, Genliang Lu, Luciano H Apponi,[...]. Nat Biotechnol 2017
137
6

Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol.
Kausik K Ray, R Scott Wright, David Kallend, Wolfgang Koenig, Lawrence A Leiter, Frederick J Raal, Jenna A Bisch, Tara Richardson, Mark Jaros, Peter L J Wijngaard,[...]. N Engl J Med 2020
237
6

Cellular uptake and trafficking of antisense oligonucleotides.
Stanley T Crooke, Shiyu Wang, Timothy A Vickers, Wen Shen, Xue-Hai Liang. Nat Biotechnol 2017
244
6

Delivery of oligonucleotide-based therapeutics: challenges and opportunities.
Suzan M Hammond, Annemieke Aartsma-Rus, Sandra Alves, Sven E Borgos, Ronald A M Buijsen, Rob W J Collin, Giuseppina Covello, Michela A Denti, Lourdes R Desviat, Lucía Echevarría,[...]. EMBO Mol Med 2021
42
14

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Sushrut Kamerkar, Valerie S LeBleu, Hikaru Sugimoto, Sujuan Yang, Carolina F Ruivo, Sonia A Melo, J Jack Lee, Raghu Kalluri. Nature 2017
958
6

Direct gene transfer into mouse muscle in vivo.
J A Wolff, R W Malone, P Williams, W Chong, G Acsadi, A Jani, P L Felgner. Science 1990
6

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study.
Richard S Finkel, Claudia A Chiriboga, Jiri Vajsar, John W Day, Jacqueline Montes, Darryl C De Vivo, Mason Yamashita, Frank Rigo, Gene Hung, Eugene Schneider,[...]. Lancet 2016
522
6

Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression.
Kian Huat Lim, Zhou Han, Hyun Yong Jeon, Jacob Kach, Enxuan Jing, Sebastien Weyn-Vanhentenryck, Mikaela Downs, Anna Corrionero, Raymond Oh, Juergen Scharner,[...]. Nat Commun 2020
40
15

Non-viral vectors for gene-based therapy.
Hao Yin, Rosemary L Kanasty, Ahmed A Eltoukhy, Arturo J Vegas, J Robert Dorkin, Daniel G Anderson. Nat Rev Genet 2014
6

Inclisiran: First Approval.
Yvette N Lamb. Drugs 2021
33
18

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.
Aurélie Goyenvalle, Graziella Griffith, Arran Babbs, Samir El Andaloussi, Kariem Ezzat, Aurélie Avril, Branislav Dugovic, Rémi Chaussenot, Arnaud Ferry, Thomas Voit,[...]. Nat Med 2015
185
6

Noncoding RNA therapeutics - challenges and potential solutions.
Melanie Winkle, Sherien M El-Daly, Muller Fabbri, George A Calin. Nat Rev Drug Discov 2021
107
6

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy.
Jerry R Mendell, Samiah Al-Zaidy, Richard Shell, W Dave Arnold, Louise R Rodino-Klapac, Thomas W Prior, Linda Lowes, Lindsay Alfano, Katherine Berry, Kathleen Church,[...]. N Engl J Med 2017
935
5

Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia.
Frederick J Raal, David Kallend, Kausik K Ray, Traci Turner, Wolfgang Koenig, R Scott Wright, Peter L J Wijngaard, Danielle Curcio, Mark J Jaros, Lawrence A Leiter,[...]. N Engl J Med 2020
158
5

A Highly Durable RNAi Therapeutic Inhibitor of PCSK9.
Kevin Fitzgerald, Suellen White, Anna Borodovsky, Brian R Bettencourt, Andrew Strahs, Valerie Clausen, Peter Wijngaard, Jay D Horton, Jorg Taubel, Ashley Brooks,[...]. N Engl J Med 2017
356
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.