A citation-based method for searching scientific literature

Akl C Fahed, Minxian Wang, Julian R Homburger, Aniruddh P Patel, Alexander G Bick, Cynthia L Neben, Carmen Lai, Deanna Brockman, Anthony Philippakis, Patrick T Ellinor, Christopher A Cassa, Matthew Lebo, Kenney Ng, Eric S Lander, Alicia Y Zhou, Sekar Kathiresan, Amit V Khera. Nat Commun 2020
Times Cited: 76







List of co-cited articles
440 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
Amit V Khera, Mark Chaffin, Krishna G Aragam, Mary E Haas, Carolina Roselli, Seung Hoan Choi, Pradeep Natarajan, Eric S Lander, Steven A Lubitz, Patrick T Ellinor,[...]. Nat Genet 2018
946
51

Clinical use of current polygenic risk scores may exacerbate health disparities.
Alicia R Martin, Masahiro Kanai, Yoichiro Kamatani, Yukinori Okada, Benjamin M Neale, Mark J Daly. Nat Genet 2019
572
26

The UK Biobank resource with deep phenotyping and genomic data.
Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T Elliott, Kevin Sharp, Allan Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O'Connell,[...]. Nature 2018
23

The mutational constraint spectrum quantified from variation in 141,456 humans.
Konrad J Karczewski, Laurent C Francioli, Grace Tiao, Beryl B Cummings, Jessica Alföldi, Qingbo Wang, Ryan L Collins, Kristen M Laricchia, Andrea Ganna, Daniel P Birnbaum,[...]. Nature 2020
23

The personal and clinical utility of polygenic risk scores.
Ali Torkamani, Nathan E Wineinger, Eric J Topol. Nat Rev Genet 2018
488
22

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.
Nasim Mavaddat, Kyriaki Michailidou, Joe Dennis, Michael Lush, Laura Fachal, Andrew Lee, Jonathan P Tyrer, Ting-Huei Chen, Qin Wang, Manjeet K Bolla,[...]. Am J Hum Genet 2019
297
21

Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting.
Pradeep Natarajan, Robin Young, Nathan O Stitziel, Sandosh Padmanabhan, Usman Baber, Roxana Mehran, Samantha Sartori, Valentin Fuster, Dermot F Reilly, Adam Butterworth,[...]. Circulation 2017
212
19

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.
Sue Richards, Nazneen Aziz, Sherri Bale, David Bick, Soma Das, Julie Gastier-Foster, Wayne W Grody, Madhuri Hegde, Elaine Lyon, Elaine Spector,[...]. Genet Med 2015
18

Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial Infarction.
Amit V Khera, Mark Chaffin, Seyedeh M Zekavat, Ryan L Collins, Carolina Roselli, Pradeep Natarajan, Judith H Lichtman, Gail D'Onofrio, Jennifer Mattera, Rachel Dreyer,[...]. Circulation 2019
101
15

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting, Frank Dudbridge, Florence Y Lai, Stephen Kaptoge, Marta Brozynska, Tingting Wang,[...]. J Am Coll Cardiol 2018
255
15

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
J L Mega, N O Stitziel, J G Smith, D I Chasman, M Caulfield, J J Devlin, F Nordio, C Hyde, C P Cannon, F Sacks,[...]. Lancet 2015
342
15

Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease.
Joshua Elliott, Barbara Bodinier, Tom A Bond, Marc Chadeau-Hyam, Evangelos Evangelou, Karel G M Moons, Abbas Dehghan, David C Muller, Paul Elliott, Ioanna Tzoulaki. JAMA 2020
113
15

A global reference for human genetic variation.
Adam Auton, Lisa D Brooks, Richard M Durbin, Erik P Garrison, Hyun Min Kang, Jan O Korbel, Jonathan L Marchini, Shane McCarthy, Gil A McVean, Gonçalo R Abecasis. Nature 2015
15

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.
Amit V Khera, Connor A Emdin, Isabel Drake, Pradeep Natarajan, Alexander G Bick, Nancy R Cook, Daniel I Chasman, Usman Baber, Roxana Mehran, Daniel J Rader,[...]. N Engl J Med 2016
536
14

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.
Karoline B Kuchenbaecker, Lesley McGuffog, Daniel Barrowdale, Andrew Lee, Penny Soucy, Joe Dennis, Susan M Domchek, Mark Robson, Amanda B Spurdle, Susan J Ramus,[...]. J Natl Cancer Inst 2017
132
14

Second-generation PLINK: rising to the challenge of larger and richer datasets.
Christopher C Chang, Carson C Chow, Laurent Cam Tellier, Shashaank Vattikuti, Shaun M Purcell, James J Lee. Gigascience 2015
13

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.
Andrew Lee, Nasim Mavaddat, Amber N Wilcox, Alex P Cunningham, Tim Carver, Simon Hartley, Chantal Babb de Villiers, Angel Izquierdo, Jacques Simard, Marjanka K Schmidt,[...]. Genet Med 2019
166
13

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.
Jonathan D Mosley, Deepak K Gupta, Jingyi Tan, Jie Yao, Quinn S Wells, Christian M Shaffer, Suman Kundu, Cassianne Robinson-Cohen, Bruce M Psaty, Stephen S Rich,[...]. JAMA 2020
103
11

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.
Amit V Khera, Hong-Hee Won, Gina M Peloso, Kim S Lawson, Traci M Bartz, Xuan Deng, Elisabeth M van Leeuwen, Pradeep Natarajan, Connor A Emdin, Alexander G Bick,[...]. J Am Coll Cardiol 2016
458
11

Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
Alicia R Martin, Christopher R Gignoux, Raymond K Walters, Genevieve L Wojcik, Benjamin M Neale, Simon Gravel, Mark J Daly, Carlos D Bustamante, Eimear E Kenny. Am J Hum Genet 2017
488
11

Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial.
Amy Damask, P Gabriel Steg, Gregory G Schwartz, Michael Szarek, Emil Hagström, Lina Badimon, M John Chapman, Catherine Boileau, Sotirios Tsimikas, Henry N Ginsberg,[...]. Circulation 2020
63
14

Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial.
Nicholas A Marston, Frederick K Kamanu, Francesco Nordio, Yared Gurmu, Carolina Roselli, Peter S Sever, Terje R Pedersen, Anthony C Keech, Huei Wang, Armando Lira Pineda,[...]. Circulation 2020
63
14

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Bjarni J Vilhjálmsson, Jian Yang, Hilary K Finucane, Alexander Gusev, Sara Lindström, Stephan Ripke, Giulio Genovese, Po-Ru Loh, Gaurav Bhatia, Ron Do,[...]. Am J Hum Genet 2015
511
11

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.
Nina Mars, Jukka T Koskela, Pietari Ripatti, Tuomo T J Kiiskinen, Aki S Havulinna, Joni V Lindbohm, Ari Ahola-Olli, Mitja Kurki, Juha Karjalainen, Priit Palta,[...]. Nat Med 2020
85
11

Quantifying the polygenic contribution to variable expressivity in eleven rare genetic disorders.
M T Oetjens, M A Kelly, A C Sturm, C L Martin, D H Ledbetter. Nat Commun 2019
36
25

Tutorial: a guide to performing polygenic risk score analyses.
Shing Wan Choi, Timothy Shin-Heng Mak, Paul F O'Reilly. Nat Protoc 2020
190
11

Improving reporting standards for polygenic scores in risk prediction studies.
Hannah Wand, Samuel A Lambert, Cecelia Tamburro, Michael A Iacocca, Jack W O'Sullivan, Catherine Sillari, Iftikhar J Kullo, Robb Rowley, Jacqueline S Dron, Deanna Brockman,[...]. Nature 2021
63
14

Towards clinical utility of polygenic risk scores.
Samuel A Lambert, Gad Abraham, Michael Inouye. Hum Mol Genet 2019
136
10

UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.
Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray,[...]. PLoS Med 2015
10

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
Philippa J Talmud, Sonia Shah, Ros Whittall, Marta Futema, Philip Howard, Jackie A Cooper, Seamus C Harrison, Kawah Li, Fotios Drenos, Frederik Karpe,[...]. Lancet 2013
370
10


A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Majid Nikpay, Anuj Goel, Hong-Hee Won, Leanne M Hall, Christina Willenborg, Stavroula Kanoni, Danish Saleheen, Theodosios Kyriakou, Christopher P Nelson, Jemma C Hopewell,[...]. Nat Genet 2015
9

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society.
Børge G Nordestgaard, M John Chapman, Steve E Humphries, Henry N Ginsberg, Luis Masana, Olivier S Descamps, Olov Wiklund, Robert A Hegele, Frederick J Raal, Joep C Defesche,[...]. Eur Heart J 2013
9

Developing and evaluating polygenic risk prediction models for stratified disease prevention.
Nilanjan Chatterjee, Jianxin Shi, Montserrat García-Closas. Nat Rev Genet 2016
316
9

Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.
Hayato Tada, Olle Melander, Judy Z Louie, Joseph J Catanese, Charles M Rowland, James J Devlin, Sekar Kathiresan, Dov Shiffman. Eur Heart J 2016
139
9


Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.
Pradeep Natarajan, Gina M Peloso, Seyedeh Maryam Zekavat, May Montasser, Andrea Ganna, Mark Chaffin, Amit V Khera, Wei Zhou, Jonathan M Bloom, Jesse M Engreitz,[...]. Nat Commun 2018
81
9

Discovery and refinement of loci associated with lipid levels.
Cristen J Willer, Ellen M Schmidt, Sebanti Sengupta, Gina M Peloso, Stefan Gustafsson, Stavroula Kanoni, Andrea Ganna, Jin Chen, Martin L Buchkovich, Samia Mora,[...]. Nat Genet 2013
9

Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia.
Mark Trinder, Xuan Li, Maria Liza DeCastro, Luba Cermakova, Singh Sadananda, Linda M Jackson, Hawmid Azizi, G B John Mancini, Gordon A Francis, Jiri Frohlich,[...]. J Am Coll Cardiol 2019
64
10


Genetic analyses of diverse populations improves discovery for complex traits.
Genevieve L Wojcik, Mariaelisa Graff, Katherine K Nishimura, Ran Tao, Jeffrey Haessler, Christopher R Gignoux, Heather M Highland, Yesha M Patel, Elena P Sorokin, Christy L Avery,[...]. Nature 2019
243
9

Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
Sarah S Kalia, Kathy Adelman, Sherri J Bale, Wendy K Chung, Christine Eng, James P Evans, Gail E Herman, Sophia B Hufnagel, Teri E Klein, Bruce R Korf,[...]. Genet Med 2017
902
9

The role of polygenic risk and susceptibility genes in breast cancer over the course of life.
Nina Mars, Elisabeth Widén, Sini Kerminen, Tuomo Meretoja, Matti Pirinen, Pietro Della Briotta Parolo, Priit Palta, Aarno Palotie, Jaakko Kaprio, Heikki Joensuu,[...]. Nat Commun 2020
20
35

10 Years of GWAS Discovery: Biology, Function, and Translation.
Peter M Visscher, Naomi R Wray, Qian Zhang, Pamela Sklar, Mark I McCarthy, Matthew A Brown, Jian Yang. Am J Hum Genet 2017
9

The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation.
Samuel A Lambert, Laurent Gil, Simon Jupp, Scott C Ritchie, Yu Xu, Annalisa Buniello, Aoife McMahon, Gad Abraham, Michael Chapman, Helen Parkinson,[...]. Nat Genet 2021
52
13

Finding the missing heritability of complex diseases.
Teri A Manolio, Francis S Collins, Nancy J Cox, David B Goldstein, Lucia A Hindorff, David J Hunter, Mark I McCarthy, Erin M Ramos, Lon R Cardon, Aravinda Chakravarti,[...]. Nature 2009
7

Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).
Iftikhar J Kullo, Hayan Jouni, Erin E Austin, Sherry-Ann Brown, Teresa M Kruisselbrink, Iyad N Isseh, Raad A Haddad, Tariq S Marroush, Khader Shameer, Janet E Olson,[...]. Circulation 2016
131
7

Genomic prediction of coronary heart disease.
Gad Abraham, Aki S Havulinna, Oneil G Bhalala, Sean G Byars, Alysha M De Livera, Laxman Yetukuri, Emmi Tikkanen, Markus Perola, Heribert Schunkert, Eric J Sijbrands,[...]. Eur Heart J 2016
154
7

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Brendan K Bulik-Sullivan, Po-Ru Loh, Hilary K Finucane, Stephan Ripke, Jian Yang, Nick Patterson, Mark J Daly, Alkes L Price, Benjamin M Neale. Nat Genet 2015
7

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.
Marianne Abifadel, Mathilde Varret, Jean-Pierre Rabès, Delphine Allard, Khadija Ouguerram, Martine Devillers, Corinne Cruaud, Suzanne Benjannet, Louise Wickham, Danièle Erlich,[...]. Nat Genet 2003
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.