A citation-based method for searching scientific literature

Theresa Klemm, Gregor Ebert, Dale J Calleja, Cody C Allison, Lachlan W Richardson, Jonathan P Bernardini, Bernadine Gc Lu, Nathan W Kuchel, Christoph Grohmann, Yuri Shibata, Zhong Yan Gan, James P Cooney, Marcel Doerflinger, Amanda E Au, Timothy R Blackmore, Gerbrand J van der Heden van Noort, Paul P Geurink, Huib Ovaa, Janet Newman, Alan Riboldi-Tunnicliffe, Peter E Czabotar, Jeffrey P Mitchell, Rebecca Feltham, Bernhard C Lechtenberg, Kym N Lowes, Grant Dewson, Marc Pellegrini, Guillaume Lessene, David Komander. EMBO J 2020
Times Cited: 178







List of co-cited articles
1187 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Donghyuk Shin, Rukmini Mukherjee, Diana Grewe, Denisa Bojkova, Kheewoong Baek, Anshu Bhattacharya, Laura Schulz, Marek Widera, Ahmad Reza Mehdipour, Georg Tascher,[...]. Nature 2020
426
71

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.
Wioletta Rut, Zongyang Lv, Mikolaj Zmudzinski, Stephanie Patchett, Digant Nayak, Scott J Snipas, Farid El Oualid, Tony T Huang, Miklos Bekes, Marcin Drag,[...]. Sci Adv 2020
191
46

Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease.
Brendan T Freitas, Ian A Durie, Jackelyn Murray, Jaron E Longo, Holden C Miller, David Crich, Robert Jeff Hogan, Ralph A Tripp, Scott D Pegan. ACS Infect Dis 2020
140
38

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng, Meiqin Liu, Yao Zhao, Bing Zhang, Xiaofeng Li, Leike Zhang, Chao Peng,[...]. Nature 2020
37

The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
Yahira M Báez-Santos, Sarah E St John, Andrew D Mesecar. Antiviral Res 2015
456
35

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.
Kiira Ratia, Scott Pegan, Jun Takayama, Katrina Sleeman, Melissa Coughlin, Surendranath Baliji, Rima Chaudhuri, Wentao Fu, Bellur S Prabhakar, Michael E Johnson,[...]. Proc Natl Acad Sci U S A 2008
281
34

The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery.
Ziyang Fu, Bin Huang, Jinle Tang, Shuyan Liu, Ming Liu, Yuxin Ye, Zhihong Liu, Yuxian Xiong, Wenning Zhu, Dan Cao,[...]. Nat Commun 2021
85
37

Crystal structure of SARS-CoV-2 papain-like protease.
Xiaopan Gao, Bo Qin, Pu Chen, Kaixiang Zhu, Pengjiao Hou, Justyna Aleksandra Wojdyla, Meitian Wang, Sheng Cui. Acta Pharm Sin B 2021
121
31

A pneumonia outbreak associated with a new coronavirus of probable bat origin.
Peng Zhou, Xing-Lou Yang, Xian-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang, Hao-Rui Si, Yan Zhu, Bei Li, Chao-Lin Huang,[...]. Nature 2020
30

Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
Jerzy Osipiuk, Saara-Anne Azizi, Steve Dvorkin, Michael Endres, Robert Jedrzejczak, Krysten A Jones, Soowon Kang, Rahul S Kathayat, Youngchang Kim, Vladislav G Lisnyak,[...]. Nat Commun 2021
135
30

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity.
Naina Barretto, Dalia Jukneliene, Kiira Ratia, Zhongbin Chen, Andrew D Mesecar, Susan C Baker. J Virol 2005
351
25

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.
Markus Hoffmann, Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Tanja Herrler, Sandra Erichsen, Tobias S Schiergens, Georg Herrler, Nai-Huei Wu, Andreas Nitsche,[...]. Cell 2020
24

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld. Science 2020
24

X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases.
Yahira M Báez-Santos, Scott J Barraza, Michael W Wilson, Michael P Agius, Anna M Mielech, Nicole M Davis, Susan C Baker, Scott D Larsen, Andrew D Mesecar. J Med Chem 2014
115
23

A new coronavirus associated with human respiratory disease in China.
Fan Wu, Su Zhao, Bin Yu, Yan-Mei Chen, Wen Wang, Zhi-Gang Song, Yi Hu, Zhao-Wu Tao, Jun-Hua Tian, Yuan-Yuan Pei,[...]. Nature 2020
21

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Wenhao Dai, Bing Zhang, Xia-Ming Jiang, Haixia Su, Jian Li, Yao Zhao, Xiong Xie, Zhenming Jin, Jingjing Peng, Fengjiang Liu,[...]. Science 2020
692
19

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu, Xiang Zhao, Juan Li, Peihua Niu, Bo Yang, Honglong Wu, Wenling Wang, Hao Song, Baoying Huang, Na Zhu,[...]. Lancet 2020
18

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme.
Kiira Ratia, Kumar Singh Saikatendu, Bernard D Santarsiero, Naina Barretto, Susan C Baker, Raymond C Stevens, Andrew D Mesecar. Proc Natl Acad Sci U S A 2006
275
18

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.
Jian Lei, Yuri Kusov, Rolf Hilgenfeld. Antiviral Res 2018
299
18

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.
GuanQun Liu, Jung-Hyun Lee, Zachary M Parker, Dhiraj Acharya, Jessica J Chiang, Michiel van Gent, William Riedl, Meredith E Davis-Gardner, Effi Wies, Cindy Chiang,[...]. Nat Microbiol 2021
92
19

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay.
Chunlong Ma, Michael Dominic Sacco, Zilei Xia, George Lambrinidis, Julia Alma Townsend, Yanmei Hu, Xiangzhi Meng, Tommy Szeto, Mandy Ba, Xiujun Zhang,[...]. ACS Cent Sci 2021
39
46

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Chunlong Ma, Michael Dominic Sacco, Brett Hurst, Julia Alma Townsend, Yanmei Hu, Tommy Szeto, Xiujun Zhang, Bart Tarbet, Michael Thomas Marty, Yu Chen,[...]. Cell Res 2020
385
17

Remdesivir for the Treatment of Covid-19 - Final Report.
John H Beigel, Kay M Tomashek, Lori E Dodd, Aneesh K Mehta, Barry S Zingman, Andre C Kalil, Elizabeth Hohmann, Helen Y Chu, Annie Luetkemeyer, Susan Kline,[...]. N Engl J Med 2020
17

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Miklós Békés, Gerbrand J van der Heden van Noort, Reggy Ekkebus, Huib Ovaa, Tony T Huang, Christopher D Lima. Mol Cell 2016
87
18

Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Yan Gao, Liming Yan, Yucen Huang, Fengjiang Liu, Yao Zhao, Lin Cao, Tao Wang, Qianqian Sun, Zhenhua Ming, Lianqi Zhang,[...]. Science 2020
761
16

Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity.
Zhengnan Shen, Kiira Ratia, Laura Cooper, Deyu Kong, Hyun Lee, Youngjin Kwon, Yangfeng Li, Saad Alqarni, Fei Huang, Oleksii Dubrovskyi,[...]. J Med Chem 2022
26
61

Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Hengyue Shan, Jianping Liu, Jiali Shen, Jialin Dai, Gang Xu, Kuankuan Lu, Chao Han, Yaru Wang, Xiaolong Xu, Yilun Tong,[...]. Cell Chem Biol 2021
23
69

High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Yao Zhao, Xiaoyu Du, Yinkai Duan, Xiaoyan Pan, Yifang Sun, Tian You, Lin Han, Zhenming Jin, Weijuan Shang, Jing Yu,[...]. Protein Cell 2021
38
39

An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Dafydd R Owen, Charlotte M N Allerton, Annaliesa S Anderson, Lisa Aschenbrenner, Melissa Avery, Simon Berritt, Britton Boras, Rhonda D Cardin, Anthony Carlo, Karen J Coffman,[...]. Science 2021
309
15

Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity.
Brian H Harcourt, Dalia Jukneliene, Amornrat Kanjanahaluethai, John Bechill, Kari M Severson, Catherine M Smith, Paul A Rota, Susan C Baker. J Virol 2004
300
14

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu,[...]. Lancet 2020
14

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.
Kiira Ratia, Andrew Kilianski, Yahira M Baez-Santos, Susan C Baker, Andrew Mesecar. PLoS Pathog 2014
132
14

The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme.
Holger A Lindner, Nasser Fotouhi-Ardakani, Viktoria Lytvyn, Paule Lachance, Traian Sulea, Robert Ménard. J Virol 2005
260
14

Coronavirus biology and replication: implications for SARS-CoV-2.
Philip V'kovski, Annika Kratzel, Silvio Steiner, Hanspeter Stalder, Volker Thiel. Nat Rev Microbiol 2021
955
14

Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.
Arun K Ghosh, Jun Takayama, Kalapala Venkateswara Rao, Kiira Ratia, Rima Chaudhuri, Debbie C Mulhearn, Hyun Lee, Daniel B Nichols, Surendranath Baliji, Susan C Baker,[...]. J Med Chem 2010
95
13

Origin and evolution of pathogenic coronaviruses.
Jie Cui, Fang Li, Zheng-Li Shi. Nat Rev Microbiol 2019
13

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.
Jun Lan, Jiwan Ge, Jinfang Yu, Sisi Shan, Huan Zhou, Shilong Fan, Qi Zhang, Xuanling Shi, Qisheng Wang, Linqi Zhang,[...]. Nature 2020
13

A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu, Dingyu Zhang, Wenling Wang, Xingwang Li, Bo Yang, Jingdong Song, Xiang Zhao, Baoying Huang, Weifeng Shi, Roujian Lu,[...]. N Engl J Med 2020
13

ISG15 in antiviral immunity and beyond.
Yi-Chieh Perng, Deborah J Lenschow. Nat Rev Microbiol 2018
225
13


A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
David E Gordon, Gwendolyn M Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M White, Matthew J O'Meara, Veronica V Rezelj, Jeffrey Z Guo, Danielle L Swaney,[...]. Nature 2020
12

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Timothy P Sheahan, Amy C Sims, Shuntai Zhou, Rachel L Graham, Andrea J Pruijssers, Maria L Agostini, Sarah R Leist, Alexandra Schäfer, Kenneth H Dinnon, Laura J Stevens,[...]. Sci Transl Med 2020
528
12

Characteristics of SARS-CoV-2 and COVID-19.
Ben Hu, Hua Guo, Peng Zhou, Zheng-Li Shi. Nat Rev Microbiol 2021
12

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir.
Wanchao Yin, Chunyou Mao, Xiaodong Luan, Dan-Dan Shen, Qingya Shen, Haixia Su, Xiaoxi Wang, Fulai Zhou, Wenfeng Zhao, Minqi Gao,[...]. Science 2020
584
11

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.
Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhengli Shi, Zhihong Hu, Wu Zhong, Gengfu Xiao. Cell Res 2020
11

Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors.
Chunlong Ma, Yanmei Hu, Julia Alma Townsend, Panagiotis I Lagarias, Michael Thomas Marty, Antonios Kolocouris, Jun Wang. ACS Pharmacol Transl Sci 2020
96
11

Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes.
Min-Han Lin, David C Moses, Chih-Hua Hsieh, Shu-Chun Cheng, Yau-Hung Chen, Chiao-Yin Sun, Chi-Yuan Chou. Antiviral Res 2018
148
10


Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
Jozlyn R Clasman, Renata K Everett, Karthik Srinivasan, Andrew D Mesecar. Antiviral Res 2020
25
40

Coronaviruses: an overview of their replication and pathogenesis.
Anthony R Fehr, Stanley Perlman. Methods Mol Biol 2015
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.