Raffaella Buzzetti, Tiinamaija Tuomi, Didac Mauricio, Massimo Pietropaolo, Zhiguang Zhou, Paolo Pozzilli, Richard David Leslie. Diabetes 2020
Times Cited: 1
Times Cited: 1
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Times Co-cited
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Tauroursodeoxycholate-Bile Acid with Chaperoning Activity: Molecular and Cellular Effects and Therapeutic Perspectives.
Magdalena Kusaczuk. Cells 2019
Magdalena Kusaczuk. Cells 2019
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Immune and Pancreatic β Cell Interactions in Type 1 Diabetes.
Joanne Boldison, F Susan Wong. Trends Endocrinol. Metab. 2016
Joanne Boldison, F Susan Wong. Trends Endocrinol. Metab. 2016
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Revisiting the role of inflammation in the loss of pancreatic β-cells in T1DM.
Decio L Eizirik, Maikel L Colli. Nat Rev Endocrinol 2020
Decio L Eizirik, Maikel L Colli. Nat Rev Endocrinol 2020
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Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders.
Kevan C Herold, Stephen E Gitelman, Mario R Ehlers, Peter A Gottlieb, Carla J Greenbaum, William Hagopian, Karen D Boyle, Lynette Keyes-Elstein, Sudeepta Aggarwal, Deborah Phippard,[...]. Diabetes 2013
Kevan C Herold, Stephen E Gitelman, Mario R Ehlers, Peter A Gottlieb, Carla J Greenbaum, William Hagopian, Karen D Boyle, Lynette Keyes-Elstein, Sudeepta Aggarwal, Deborah Phippard,[...]. Diabetes 2013
100
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.
Reut Yosef, Noam Pilpel, Ronit Tokarsky-Amiel, Anat Biran, Yossi Ovadya, Snir Cohen, Ezra Vadai, Liat Dassa, Elisheva Shahar, Reba Condiotti,[...]. Nat Commun 2016
Reut Yosef, Noam Pilpel, Ronit Tokarsky-Amiel, Anat Biran, Yossi Ovadya, Snir Cohen, Ezra Vadai, Liat Dassa, Elisheva Shahar, Reba Condiotti,[...]. Nat Commun 2016
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Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.
Jay S Skyler, George L Bakris, Ezio Bonifacio, Tamara Darsow, Robert H Eckel, Leif Groop, Per-Henrik Groop, Yehuda Handelsman, Richard A Insel, Chantal Mathieu,[...]. Diabetes 2017
Jay S Skyler, George L Bakris, Ezio Bonifacio, Tamara Darsow, Robert H Eckel, Leif Groop, Per-Henrik Groop, Yehuda Handelsman, Richard A Insel, Chantal Mathieu,[...]. Diabetes 2017
100
Mitochondrial Reactive Oxygen Species and Type 1 Diabetes.
Jing Chen, Scott E Stimpson, Gabriel A Fernandez-Bueno, Clayton E Mathews. Antioxid. Redox Signal. 2018
Jing Chen, Scott E Stimpson, Gabriel A Fernandez-Bueno, Clayton E Mathews. Antioxid. Redox Signal. 2018
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ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol. Cell 2017
Andrew N Blackford, Stephen P Jackson. Mol. Cell 2017
100
A combined risk score enhances prediction of type 1 diabetes among susceptible children.
Lauric A Ferrat, Kendra Vehik, Seth A Sharp, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Anette-G Ziegler, Jorma Toppari, Beena Akolkar, Jeffrey P Krischer,[...]. Nat Med 2020
Lauric A Ferrat, Kendra Vehik, Seth A Sharp, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Anette-G Ziegler, Jorma Toppari, Beena Akolkar, Jeffrey P Krischer,[...]. Nat Med 2020
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Cell death: a review of the major forms of apoptosis, necrosis and autophagy.
Mark S D'Arcy. Cell Biol. Int. 2019
Mark S D'Arcy. Cell Biol. Int. 2019
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Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
100
Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically.
Abdiaziz S Mohamood, Mehmet L Guler, Zuoxiang Xiao, Dongfeng Zheng, Allan Hess, Yi Wang, Hideo Yagita, Jonathan P Schneck, Abdel Rahim A Hamad. Am. J. Pathol. 2007
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Targeting senescent cells in translational medicine.
Marta Paez-Ribes, Estela González-Gualda, Gary J Doherty, Daniel Muñoz-Espín. EMBO Mol Med 2019
Marta Paez-Ribes, Estela González-Gualda, Gary J Doherty, Daniel Muñoz-Espín. EMBO Mol Med 2019
100
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction.
Maikel L Colli, Jessica L E Hill, Laura Marroquí, Jessica Chaffey, Reinaldo S Dos Santos, Pia Leete, Alexandra Coomans de Brachène, Flavia M M Paula, Anne Op de Beeck, Angela Castela,[...]. EBioMedicine 2018
Maikel L Colli, Jessica L E Hill, Laura Marroquí, Jessica Chaffey, Reinaldo S Dos Santos, Pia Leete, Alexandra Coomans de Brachène, Flavia M M Paula, Anne Op de Beeck, Angela Castela,[...]. EBioMedicine 2018
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Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice.
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Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.
Emily K Sims, Henry T Bahnson, Julius Nyalwidhe, Leena Haataja, Asa K Davis, Cate Speake, Linda A DiMeglio, Janice Blum, Margaret A Morris, Raghavendra G Mirmira,[...]. Diabetes Care 2019
Emily K Sims, Henry T Bahnson, Julius Nyalwidhe, Leena Haataja, Asa K Davis, Cate Speake, Linda A DiMeglio, Janice Blum, Margaret A Morris, Raghavendra G Mirmira,[...]. Diabetes Care 2019
100
Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.
Clive Wasserfall, Harry S Nick, Martha Campbell-Thompson, Dawn Beachy, Leena Haataja, Irina Kusmartseva, Amanda Posgai, Maria Beery, Christopher Rhodes, Ezio Bonifacio,[...]. Cell Metab. 2017
Clive Wasserfall, Harry S Nick, Martha Campbell-Thompson, Dawn Beachy, Leena Haataja, Irina Kusmartseva, Amanda Posgai, Maria Beery, Christopher Rhodes, Ezio Bonifacio,[...]. Cell Metab. 2017
100
Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat. Med. 2018
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat. Med. 2018
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Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice.
D Kägi, B Odermatt, P Seiler, R M Zinkernagel, T W Mak, H Hengartner. J. Exp. Med. 1997
D Kägi, B Odermatt, P Seiler, R M Zinkernagel, T W Mak, H Hengartner. J. Exp. Med. 1997
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IRE1: ER stress sensor and cell fate executor.
Yani Chen, Federica Brandizzi. Trends Cell Biol. 2013
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Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Harini Chakravarthy, Xueying Gu, Martin Enge, Xiaoqing Dai, Yong Wang, Nicolas Damond, Carolina Downie, Kathy Liu, Jing Wang, Yuan Xing,[...]. Cell Metab. 2017
Harini Chakravarthy, Xueying Gu, Martin Enge, Xiaoqing Dai, Yong Wang, Nicolas Damond, Carolina Downie, Kathy Liu, Jing Wang, Yuan Xing,[...]. Cell Metab. 2017
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Impact of islet architecture on β-cell heterogeneity, plasticity and function.
Sara S Roscioni, Adriana Migliorini, Moritz Gegg, Heiko Lickert. Nat Rev Endocrinol 2016
Sara S Roscioni, Adriana Migliorini, Moritz Gegg, Heiko Lickert. Nat Rev Endocrinol 2016
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A review on insulin trafficking and exocytosis.
Mehrdad Vakilian, Yaser Tahamtani, Kamran Ghaedi. Gene 2019
Mehrdad Vakilian, Yaser Tahamtani, Kamran Ghaedi. Gene 2019
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Senescence and apoptosis: dueling or complementary cell fates?
Bennett G Childs, Darren J Baker, James L Kirkland, Judith Campisi, Jan M van Deursen. EMBO Rep. 2014
Bennett G Childs, Darren J Baker, James L Kirkland, Judith Campisi, Jan M van Deursen. EMBO Rep. 2014
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Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.
Qing Li, Baohui Xu, Sara A Michie, Kathleen H Rubins, Robert D Schreriber, Hugh O McDevitt. Proc. Natl. Acad. Sci. U.S.A. 2008
Qing Li, Baohui Xu, Sara A Michie, Kathleen H Rubins, Robert D Schreriber, Hugh O McDevitt. Proc. Natl. Acad. Sci. U.S.A. 2008
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The challenge of modulating β-cell autoimmunity in type 1 diabetes.
Mark A Atkinson, Bart O Roep, Amanda Posgai, Daniel C S Wheeler, Mark Peakman. Lancet Diabetes Endocrinol 2019
Mark A Atkinson, Bart O Roep, Amanda Posgai, Daniel C S Wheeler, Mark Peakman. Lancet Diabetes Endocrinol 2019
100
Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes.
Joan Camunas-Soler, Xiao-Qing Dai, Yan Hang, Austin Bautista, James Lyon, Kunimasa Suzuki, Seung K Kim, Stephen R Quake, Patrick E MacDonald. Cell Metab. 2020
Joan Camunas-Soler, Xiao-Qing Dai, Yan Hang, Austin Bautista, James Lyon, Kunimasa Suzuki, Seung K Kim, Stephen R Quake, Patrick E MacDonald. Cell Metab. 2020
100
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
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Alana G Lerner, John-Paul Upton, P V K Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J Backes, Myriam Heiman,[...]. Cell Metab. 2012
100
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
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Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
Christine M Oslowski, Takashi Hara, Bryan O'Sullivan-Murphy, Kohsuke Kanekura, Simin Lu, Mariko Hara, Shinsuke Ishigaki, Lihua J Zhu, Emiko Hayashi, Simon T Hui,[...]. Cell Metab. 2012
Christine M Oslowski, Takashi Hara, Bryan O'Sullivan-Murphy, Kohsuke Kanekura, Simin Lu, Mariko Hara, Shinsuke Ishigaki, Lihua J Zhu, Emiko Hayashi, Simon T Hui,[...]. Cell Metab. 2012
100
Senescent cell clearance by the immune system: Emerging therapeutic opportunities.
Larissa G P Langhi Prata, Inna G Ovsyannikova, Tamara Tchkonia, James L Kirkland. Semin. Immunol. 2018
Larissa G P Langhi Prata, Inna G Ovsyannikova, Tamara Tchkonia, James L Kirkland. Semin. Immunol. 2018
100
Application of ursodeoxycholic acid (UDCA) in the therapy of liver and biliary duct diseases in children.
D M Lebensztejn. Med. Sci. Monit. 2000
D M Lebensztejn. Med. Sci. Monit. 2000
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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.
Martin Enge, H Efsun Arda, Marco Mignardi, John Beausang, Rita Bottino, Seung K Kim, Stephen R Quake. Cell 2017
Martin Enge, H Efsun Arda, Marco Mignardi, John Beausang, Rita Bottino, Seung K Kim, Stephen R Quake. Cell 2017
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Reducing Senescent Cell Burden in Aging and Disease.
Robert J Pignolo, João F Passos, Sundeep Khosla, Tamara Tchkonia, James L Kirkland. Trends Mol Med 2020
Robert J Pignolo, João F Passos, Sundeep Khosla, Tamara Tchkonia, James L Kirkland. Trends Mol Med 2020
100
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.
Sarina A Piha-Paul, Christine L Hann, Christopher A French, Sophie Cousin, Irene Braña, Phillippe A Cassier, Victor Moreno, Johann S de Bono, Sara Duckworth Harward, Geraldine Ferron-Brady,[...].  2019
Sarina A Piha-Paul, Christine L Hann, Christopher A French, Sophie Cousin, Irene Braña, Phillippe A Cassier, Victor Moreno, Johann S de Bono, Sara Duckworth Harward, Geraldine Ferron-Brady,[...].  2019
100
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
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100
Randomized 52-week Phase 2 Trial of Albiglutide Versus Placebo in Adult Patients With Newly Diagnosed Type 1 Diabetes.
Paolo Pozzilli, Emanuele Bosi, Deborah Cirkel, Julia Harris, Nicola Leech, Francisco J Tinahones, Marie-Christine Vantyghem, Georgios Vlasakakis, Anette-Gabriele Ziegler, Salim Janmohamed. J. Clin. Endocrinol. Metab. 2020
Paolo Pozzilli, Emanuele Bosi, Deborah Cirkel, Julia Harris, Nicola Leech, Francisco J Tinahones, Marie-Christine Vantyghem, Georgios Vlasakakis, Anette-Gabriele Ziegler, Salim Janmohamed. J. Clin. Endocrinol. Metab. 2020
100
The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes.
James A Pearson, F Susan Wong, Li Wen. J. Autoimmun. 2016
James A Pearson, F Susan Wong, Li Wen. J. Autoimmun. 2016
100
Viral infections in type 1 diabetes mellitus--why the β cells?
Anne Op de Beeck, Decio L Eizirik. Nat Rev Endocrinol 2016
Anne Op de Beeck, Decio L Eizirik. Nat Rev Endocrinol 2016
100
The remission phase in type 1 diabetes: Changing epidemiology, definitions, and emerging immuno-metabolic mechanisms.
Ting Zhong, Rong Tang, Siyuan Gong, Juan Li, Xia Li, Zhiguang Zhou. Diabetes Metab Res Rev 2020
Ting Zhong, Rong Tang, Siyuan Gong, Juan Li, Xia Li, Zhiguang Zhou. Diabetes Metab Res Rev 2020
100
Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.
Sarah A Tersey, Yurika Nishiki, Andrew T Templin, Susanne M Cabrera, Natalie D Stull, Stephanie C Colvin, Carmella Evans-Molina, Jenna L Rickus, Bernhard Maier, Raghavendra G Mirmira. Diabetes 2012
Sarah A Tersey, Yurika Nishiki, Andrew T Templin, Susanne M Cabrera, Natalie D Stull, Stephanie C Colvin, Carmella Evans-Molina, Jenna L Rickus, Bernhard Maier, Raghavendra G Mirmira. Diabetes 2012
100
Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?).
Bart O Roep, Sofia Thomaidou, René van Tienhoven, Arnaud Zaldumbide. Nat Rev Endocrinol 2020
Bart O Roep, Sofia Thomaidou, René van Tienhoven, Arnaud Zaldumbide. Nat Rev Endocrinol 2020
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Cellular senescence drives age-dependent hepatic steatosis.
Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L Wilson, Albert Lahat, Christoper P Day, Alastair Burt, Allyson Palmer, Quentin M Anstee,[...]. Nat Commun 2017
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p16INK4a induces an age-dependent decline in islet regenerative potential.
Janakiraman Krishnamurthy, Matthew R Ramsey, Keith L Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir, Norman E Sharpless. Nature 2006
Janakiraman Krishnamurthy, Matthew R Ramsey, Keith L Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir, Norman E Sharpless. Nature 2006
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Cellular Senescence as the Causal Nexus of Aging.
Naina Bhatia-Dey, Riya R Kanherkar, Susan E Stair, Evgeny O Makarev, Antonei B Csoka.  2016
Naina Bhatia-Dey, Riya R Kanherkar, Susan E Stair, Evgeny O Makarev, Antonei B Csoka.  2016
100
Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
Talitha van der Meulen, Alex M Mawla, Michael R DiGruccio, Michael W Adams, Vera Nies, Sophie Dólleman, Siming Liu, Amanda M Ackermann, Elena Cáceres, Anna E Hunter,[...]. Cell Metab. 2017
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Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes.
Peter J Thompson, Ajit Shah, Vasilis Ntranos, Frederic Van Gool, Mark Atkinson, Anil Bhushan. Cell Metab. 2019
Peter J Thompson, Ajit Shah, Vasilis Ntranos, Frederic Van Gool, Mark Atkinson, Anil Bhushan. Cell Metab. 2019
100
Low-Level Insulin Content Within Abundant Non-β Islet Endocrine Cells in Long-standing Type 1 Diabetes.
Carol J Lam, Anirudha Chatterjee, Emily Shen, Aaron R Cox, Jake A Kushner. Diabetes 2019
Carol J Lam, Anirudha Chatterjee, Emily Shen, Aaron R Cox, Jake A Kushner. Diabetes 2019
100
Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes.
Anne Jörns, Dirk Wedekind, Joachim Jähne, Sigurd Lenzen. Diabetes 2020
Anne Jörns, Dirk Wedekind, Joachim Jähne, Sigurd Lenzen. Diabetes 2020
100
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.