A citation-based method for searching scientific literature

David C Swinney, Jonathan A Lee. F1000Res 2020
Times Cited: 16







List of co-cited articles
68 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Opportunities and challenges in phenotypic drug discovery: an industry perspective.
John G Moffat, Fabien Vincent, Jonathan A Lee, Jörg Eder, Marco Prunotto. Nat Rev Drug Discov 2017
341
50

Applications of machine learning in drug discovery and development.
Jessica Vamathevan, Dominic Clark, Paul Czodrowski, Ian Dunham, Edgardo Ferran, George Lee, Bin Li, Anant Madabhushi, Parantu Shah, Michaela Spitzer,[...]. Nat Rev Drug Discov 2019
401
25

Rethinking drug design in the artificial intelligence era.
Petra Schneider, W Patrick Walters, Alleyn T Plowright, Norman Sieroka, Jennifer Listgarten, Robert A Goodnow, Jasmin Fisher, Johanna M Jansen, José S Duca, Thomas S Rush,[...]. Nat Rev Drug Discov 2020
146
25

How were new medicines discovered?
David C Swinney, Jason Anthony. Nat Rev Drug Discov 2011
18

Developing predictive assays: the phenotypic screening "rule of 3".
Fabien Vincent, Paula Loria, Marko Pregel, Robert Stanton, Linda Kitching, Karl Nocka, Regis Doyonnas, Claire Steppan, Adam Gilbert, Thomas Schroeter,[...]. Sci Transl Med 2015
107
18

How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice.
Dorothea Haasen, Ulrich Schopfer, Christophe Antczak, Chantale Guy, Florian Fuchs, Paul Selzer. Assay Drug Dev Technol 2017
37
18

Hit Triage and Validation in Phenotypic Screening: Considerations and Strategies.
Fabien Vincent, Paula M Loria, Andrea D Weston, Claire M Steppan, Regis Doyonnas, Yue-Ming Wang, Kristin L Rockwell, Marie-Claire Peakman. Cell Chem Biol 2020
15
20

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou, Yann Jamin, Javier Fernández-Mateos, Khurum Khan, Andrea Lampis, Katherine Eason, Ian Huntingford, Rosemary Burke,[...]. Science 2018
709
18

Antitumor activity of thalidomide in refractory multiple myeloma.
S Singhal, J Mehta, R Desikan, D Ayers, P Roberson, P Eddlemon, N Munshi, E Anaissie, C Wilson, M Dhodapkar,[...]. N Engl J Med 1999
18

Prospective derivation of a living organoid biobank of colorectal cancer patients.
Marc van de Wetering, Hayley E Francies, Joshua M Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk, Winan van Houdt, Joost van Gorp, Amaro Taylor-Weiner, Lennart Kester,[...]. Cell 2015
18

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.
Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko, Takahiro Seki, E Andreas Larsson, Chen Dan, Lekshmy Sreekumar, Yihai Cao, Pär Nordlund. Science 2013
895
18

The discovery of first-in-class drugs: origins and evolution.
Jörg Eder, Richard Sedrani, Christian Wiesmann. Nat Rev Drug Discov 2014
246
18

Next-Generation Phenotypic Screening in Early Drug Discovery for Infectious Diseases.
Nathalie Aulner, Anne Danckaert, JongEun Ihm, David Shum, Spencer L Shorte. Trends Parasitol 2019
30
18

Deep Learning for Deep Chemistry: Optimizing the Prediction of Chemical Patterns.
Tânia F G G Cova, Alberto A C C Pais. Front Chem 2019
25
18

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.
Mark-Anthony Bray, Shantanu Singh, Han Han, Chadwick T Davis, Blake Borgeson, Cathy Hartland, Maria Kost-Alimova, Sigrun M Gustafsdottir, Christopher C Gibson, Anne E Carpenter. Nat Protoc 2016
224
12

Phenotypic chemical biology for predicting safety and efficacy.
Ellen L Berg. Drug Discov Today Technol 2017
18
12

Screening out irrelevant cell-based models of disease.
Peter Horvath, Nathalie Aulner, Marc Bickle, Anthony M Davies, Elaine Del Nery, Daniel Ebner, Maria C Montoya, Päivi Östling, Vilja Pietiäinen, Leo S Price,[...]. Nat Rev Drug Discov 2016
262
12

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Aravind Subramanian, Rajiv Narayan, Steven M Corsello, David D Peck, Ted E Natoli, Xiaodong Lu, Joshua Gould, John F Davis, Andrew A Tubelli, Jacob K Asiedu,[...]. Cell 2017
12


A brief history of organoids.
Claudia Corrò, Laura Novellasdemunt, Vivian S W Li. Am J Physiol Cell Physiol 2020
49
12

The Convergence of Stem Cell Technologies and Phenotypic Drug Discovery.
Alexandra Friese, Andrei Ursu, Andreas Hochheimer, Hans R Schöler, Herbert Waldmann, Jan M Bruder. Cell Chem Biol 2019
20
12

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms.
Nicole C Kleinstreuer, Jian Yang, Ellen L Berg, Thomas B Knudsen, Ann M Richard, Matthew T Martin, David M Reif, Richard S Judson, Mark Polokoff, David J Dix,[...]. Nat Biotechnol 2014
126
12

Quantitative reactivity profiling predicts functional cysteines in proteomes.
Eranthie Weerapana, Chu Wang, Gabriel M Simon, Florian Richter, Sagar Khare, Myles B D Dillon, Daniel A Bachovchin, Kerri Mowen, David Baker, Benjamin F Cravatt. Nature 2010
856
12

Concerns, challenges and promises of high-content analysis of 3D cellular models.
Neil Carragher, Filippo Piccinini, Anna Tesei, O Joseph Trask, Marc Bickle, Peter Horvath. Nat Rev Drug Discov 2018
39
12

High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines.
Channing Yu, Aristotle M Mannan, Griselda Metta Yvone, Kenneth N Ross, Yan-Ling Zhang, Melissa A Marton, Bradley R Taylor, Andrew Crenshaw, Joshua Z Gould, Pablo Tamayo,[...]. Nat Biotechnol 2016
112
12



Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
Faye Marie Drawnel, Jitao David Zhang, Erich Küng, Natsuyo Aoyama, Fethallah Benmansour, Andrea Araujo Del Rosario, Sannah Jensen Zoffmann, Frédéric Delobel, Michael Prummer, Franziska Weibel,[...]. Cell Chem Biol 2017
21
12

Human organoids: model systems for human biology and medicine.
Jihoon Kim, Bon-Kyoung Koo, Juergen A Knoblich. Nat Rev Mol Cell Biol 2020
381
12

Machine learning-powered antibiotics phenotypic drug discovery.
Sannah Zoffmann, Maarten Vercruysse, Fethallah Benmansour, Andreas Maunz, Luise Wolf, Rita Blum Marti, Tobias Heckel, Haiyuan Ding, Hoa Hue Truong, Michael Prummer,[...]. Sci Rep 2019
34
12

Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets.
Prson Gautam, Alok Jaiswal, Tero Aittokallio, Hassan Al-Ali, Krister Wennerberg. Cell Chem Biol 2019
21
12

Defining a Cancer Dependency Map.
Aviad Tsherniak, Francisca Vazquez, Phil G Montgomery, Barbara A Weir, Gregory Kryukov, Glenn S Cowley, Stanley Gill, William F Harrington, Sasha Pantel, John M Krill-Burger,[...]. Cell 2017
801
12

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.
Gang Lu, Richard E Middleton, Huahang Sun, MarkVic Naniong, Christopher J Ott, Constantine S Mitsiades, Kwok-Kin Wong, James E Bradner, William G Kaelin. Science 2014
840
12

The role of ligand efficiency metrics in drug discovery.
Andrew L Hopkins, György M Keserü, Paul D Leeson, David C Rees, Charles H Reynolds. Nat Rev Drug Discov 2014
572
12

QSAR modeling: where have you been? Where are you going to?
Artem Cherkasov, Eugene N Muratov, Denis Fourches, Alexandre Varnek, Igor I Baskin, Mark Cronin, John Dearden, Paola Gramatica, Yvonne C Martin, Roberto Todeschini,[...]. J Med Chem 2014
737
12

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease.
Alice Douangamath, Daren Fearon, Paul Gehrtz, Tobias Krojer, Petra Lukacik, C David Owen, Efrat Resnick, Claire Strain-Damerell, Anthony Aimon, Péter Ábrányi-Balogh,[...]. Nat Commun 2020
173
12

Artificial intelligence in drug development: present status and future prospects.
Kit-Kay Mak, Mallikarjuna Rao Pichika. Drug Discov Today 2019
122
12

Opportunity Knocks: Organic Chemistry for Fragment-Based Drug Discovery (FBDD).
Christopher W Murray, David C Rees. Angew Chem Int Ed Engl 2016
98
12

The Synthesizability of Molecules Proposed by Generative Models.
Wenhao Gao, Connor W Coley. J Chem Inf Model 2020
59
12

GuacaMol: Benchmarking Models for de Novo Molecular Design.
Nathan Brown, Marco Fiscato, Marwin H S Segler, Alain C Vaucher. J Chem Inf Model 2019
140
12

Pfam: The protein families database in 2021.
Jaina Mistry, Sara Chuguransky, Lowri Williams, Matloob Qureshi, Gustavo A Salazar, Erik L L Sonnhammer, Silvio C E Tosatto, Lisanna Paladin, Shriya Raj, Lorna J Richardson,[...]. Nucleic Acids Res 2021
661
12

A 'rule of three' for fragment-based lead discovery?
Miles Congreve, Robin Carr, Chris Murray, Harren Jhoti. Drug Discov Today 2003
771
12

Ultra-large library docking for discovering new chemotypes.
Jiankun Lyu, Sheng Wang, Trent E Balius, Isha Singh, Anat Levit, Yurii S Moroz, Matthew J O'Meara, Tao Che, Enkhjargal Algaa, Kateryna Tolmachova,[...]. Nature 2019
273
12


Machine learning in chemoinformatics and drug discovery.
Yu-Chen Lo, Stefano E Rensi, Wen Torng, Russ B Altman. Drug Discov Today 2018
279
12

Will Artificial Intelligence for Drug Discovery Impact Clinical Pharmacology?
Alex Zhavoronkov, Quentin Vanhaelen, Tudor I Oprea. Clin Pharmacol Ther 2020
20
12

Concepts of Artificial Intelligence for Computer-Assisted Drug Discovery.
Xin Yang, Yifei Wang, Ryan Byrne, Gisbert Schneider, Shengyong Yang. Chem Rev 2019
166
12

Molecular de-novo design through deep reinforcement learning.
Marcus Olivecrona, Thomas Blaschke, Ola Engkvist, Hongming Chen. J Cheminform 2017
260
12

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.
Scott C Baraban, Matthew T Dinday, Gabriela A Hortopan. Nat Commun 2013
231
12



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.