A citation-based method for searching scientific literature

John H Stone, Matthew J Frigault, Naomi J Serling-Boyd, Ana D Fernandes, Liam Harvey, Andrea S Foulkes, Nora K Horick, Brian C Healy, Ruta Shah, Ana Maria Bensaci, Ann E Woolley, Sarah Nikiforow, Nina Lin, Manish Sagar, Harry Schrager, David S Huckins, Matthew Axelrod, Michael D Pincus, Jorge Fleisher, Chana A Sacks, Michael Dougan, Crystal M North, Yuan-Di Halvorsen, Tara K Thurber, Zeina Dagher, Allison Scherer, Rachel S Wallwork, Arthur Y Kim, Sara Schoenfeld, Pritha Sen, Tomas G Neilan, Cory A Perugino, Sebastian H Unizony, Deborah S Collier, Mark A Matza, Janeth M Yinh, Kathryn A Bowman, Eric Meyerowitz, Amna Zafar, Zsofia D Drobni, Marcy B Bolster, Minna Kohler, Kristin M D'Silva, Jonathan Dau, Megan M Lockwood, Caroline Cubbison, Brittany N Weber, Michael K Mansour. N Engl J Med 2020
Times Cited: 728







List of co-cited articles
681 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia.
Carlos Salama, Jian Han, Linda Yau, William G Reiss, Benjamin Kramer, Jeffrey D Neidhart, Gerard J Criner, Emma Kaplan-Lewis, Rachel Baden, Lavannya Pandit,[...]. N Engl J Med 2021
566
58

Dexamethasone in Hospitalized Patients with Covid-19.
Peter Horby, Wei Shen Lim, Jonathan R Emberson, Marion Mafham, Jennifer L Bell, Louise Linsell, Natalie Staplin, Christopher Brightling, Andrew Ustianowski, Einas Elmahi,[...]. N Engl J Med 2021
56

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19.
Anthony C Gordon, Paul R Mouncey, Farah Al-Beidh, Kathryn M Rowan, Alistair D Nichol, Yaseen M Arabi, Djillali Annane, Abi Beane, Wilma van Bentum-Puijk, Lindsay R Berry,[...]. N Engl J Med 2021
650
54

Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia.
Ivan O Rosas, Norbert Bräu, Michael Waters, Ronaldo C Go, Bradley D Hunter, Sanjay Bhagani, Daniel Skiest, Mariam S Aziz, Nichola Cooper, Ivor S Douglas,[...]. N Engl J Med 2021
372
51

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical Trial.
Olivier Hermine, Xavier Mariette, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Raphaël Porcher, Philippe Ravaud. JAMA Intern Med 2021
428
48

Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial.
Carlo Salvarani, Giovanni Dolci, Marco Massari, Domenico Franco Merlo, Silvio Cavuto, Luisa Savoldi, Paolo Bruzzi, Fabrizio Boni, Luca Braglia, Caterina Turrà,[...]. JAMA Intern Med 2021
382
46


Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial.
Viviane C Veiga, João A G G Prats, Danielle L C Farias, Regis G Rosa, Leticia K Dourado, Fernando G Zampieri, Flávia R Machado, Renato D Lopes, Otavio Berwanger, Luciano C P Azevedo,[...]. BMJ 2021
197
31

Remdesivir for the Treatment of Covid-19 - Final Report.
John H Beigel, Kay M Tomashek, Lori E Dodd, Aneesh K Mehta, Barry S Zingman, Andre C Kalil, Elizabeth Hohmann, Helen Y Chu, Annie Luetkemeyer, Susan Kline,[...]. N Engl J Med 2020
29

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu,[...]. Lancet 2020
23

Tocilizumab in patients with severe COVID-19: a retrospective cohort study.
Giovanni Guaraldi, Marianna Meschiari, Alessandro Cozzi-Lepri, Jovana Milic, Roberto Tonelli, Marianna Menozzi, Erica Franceschini, Gianluca Cuomo, Gabriella Orlando, Vanni Borghi,[...]. Lancet Rheumatol 2020
575
22

COVID-19: consider cytokine storm syndromes and immunosuppression.
Puja Mehta, Daniel F McAuley, Michael Brown, Emilie Sanchez, Rachel S Tattersall, Jessica J Manson. Lancet 2020
20

Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial.
Arvinder S Soin, Kuldeep Kumar, Narendra S Choudhary, Pooja Sharma, Yatin Mehta, Sushila Kataria, Deepak Govil, Vikas Deswal, Dhruva Chaudhry, Pawan Kumar Singh,[...]. Lancet Respir Med 2021
96
20

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.
Jonathan A C Sterne, Srinivas Murthy, Janet V Diaz, Arthur S Slutsky, Jesús Villar, Derek C Angus, Djillali Annane, Luciano Cesar Pontes Azevedo, Otavio Berwanger, Alexandre B Cavalcanti,[...]. JAMA 2020
17

Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial.
François-Xavier Lescure, Hitoshi Honda, Robert A Fowler, Jennifer Sloane Lazar, Genming Shi, Peter Wung, Naimish Patel, Owen Hagino. Lancet Respir Med 2021
105
17

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis.
Manu Shankar-Hari, Claire L Vale, Peter J Godolphin, David Fisher, Julian P T Higgins, Francesca Spiga, Jelena Savovic, Jayne Tierney, Gabriel Baron, Julie S Benbenishty,[...]. JAMA 2021
181
17

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.
Andre C Kalil, Thomas F Patterson, Aneesh K Mehta, Kay M Tomashek, Cameron R Wolfe, Varduhi Ghazaryan, Vincent C Marconi, Guillermo M Ruiz-Palacios, Lanny Hsieh, Susan Kline,[...]. N Engl J Med 2021
660
16

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou, Ting Yu, Ronghui Du, Guohui Fan, Ying Liu, Zhibo Liu, Jie Xiang, Yeming Wang, Bin Song, Xiaoying Gu,[...]. Lancet 2020
15

Tocilizumab for Treatment of Mechanically Ventilated Patients With COVID-19.
Emily C Somers, Gregory A Eschenauer, Jonathan P Troost, Jonathan L Golob, Tejal N Gandhi, Lu Wang, Nina Zhou, Lindsay A Petty, Ji Hoon Baang, Nicholas O Dillman,[...]. Clin Infect Dis 2021
243
15

An inflammatory cytokine signature predicts COVID-19 severity and survival.
Diane Marie Del Valle, Seunghee Kim-Schulze, Hsin-Hui Huang, Noam D Beckmann, Sharon Nirenberg, Bo Wang, Yonit Lavin, Talia H Swartz, Deepu Madduri, Aryeh Stock,[...]. Nat Med 2020
862
13

Effective treatment of severe COVID-19 patients with tocilizumab.
Xiaoling Xu, Mingfeng Han, Tiantian Li, Wei Sun, Dongsheng Wang, Binqing Fu, Yonggang Zhou, Xiaohu Zheng, Yun Yang, Xiuyong Li,[...]. Proc Natl Acad Sci U S A 2020
13

Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19.
Shruti Gupta, Wei Wang, Salim S Hayek, Lili Chan, Kusum S Mathews, Michal L Melamed, Samantha K Brenner, Amanda Leonberg-Yoo, Edward J Schenck, Jared Radbel,[...]. JAMA Intern Med 2021
213
12

Clinical and immunological features of severe and moderate coronavirus disease 2019.
Guang Chen, Di Wu, Wei Guo, Yong Cao, Da Huang, Hongwu Wang, Tao Wang, Xiaoyun Zhang, Huilong Chen, Haijing Yu,[...]. J Clin Invest 2020
12

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial.
Bruno M Tomazini, Israel S Maia, Alexandre B Cavalcanti, Otavio Berwanger, Regis G Rosa, Viviane C Veiga, Alvaro Avezum, Renato D Lopes, Flavia R Bueno, Maria Vitoria A O Silva,[...]. JAMA 2020
520
12

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Derek C Angus, Lennie Derde, Farah Al-Beidh, Djillali Annane, Yaseen Arabi, Abigail Beane, Wilma van Bentum-Puijk, Lindsay Berry, Zahra Bhimani, Marc Bonten,[...]. JAMA 2020
364
12

Cytokine Storm.
David C Fajgenbaum, Carl H June. N Engl J Med 2020
713
12

Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes.
Daniel E Leisman, Lukas Ronner, Rachel Pinotti, Matthew D Taylor, Pratik Sinha, Carolyn S Calfee, Alexandre V Hirayama, Fiore Mastroiani, Cameron J Turtle, Michael O Harhay,[...]. Lancet Respir Med 2020
383
11

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Daniel Blanco-Melo, Benjamin E Nilsson-Payant, Wen-Chun Liu, Skyler Uhl, Daisy Hoagland, Rasmus Møller, Tristan X Jordan, Kohei Oishi, Maryline Panis, David Sachs,[...]. Cell 2020
11

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.
Maximilian Ackermann, Stijn E Verleden, Mark Kuehnel, Axel Haverich, Tobias Welte, Florian Laenger, Arno Vanstapel, Christopher Werlein, Helge Stark, Alexandar Tzankov,[...]. N Engl J Med 2020
11

Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Hongchao Pan, Richard Peto, Ana-Maria Henao-Restrepo, Marie-Pierre Preziosi, Vasee Sathiyamoorthy, Quarraisha Abdool Karim, Marissa M Alejandria, César Hernández García, Marie-Paule Kieny, Reza Malekzadeh,[...]. N Engl J Med 2021
11

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19.
Tobias Herold, Vindi Jurinovic, Chiara Arnreich, Brian J Lipworth, Johannes C Hellmuth, Michael von Bergwelt-Baildon, Matthias Klein, Tobias Weinberger. J Allergy Clin Immunol 2020
453
11


Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Peter Horby, Marion Mafham, Louise Linsell, Jennifer L Bell, Natalie Staplin, Jonathan R Emberson, Martin Wiselka, Andrew Ustianowski, Einas Elmahi, Benjamin Prudon,[...]. N Engl J Med 2020
617
10

Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Brescia, Italy.
Paola Toniati, Simone Piva, Marco Cattalini, Emirena Garrafa, Francesca Regola, Francesco Castelli, Franco Franceschini, Paolo Airò, Chiara Bazzani, Eva-Andrea Beindorf,[...]. Autoimmun Rev 2020
481
10

Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia.
Patrícia O Guimarães, Daniel Quirk, Remo H Furtado, Lilia N Maia, José F Saraiva, Murillo O Antunes, Roberto Kalil Filho, Vagner M Junior, Alexandre M Soeiro, Alexandre P Tognon,[...]. N Engl J Med 2021
129
10

Longitudinal analyses reveal immunological misfiring in severe COVID-19.
Carolina Lucas, Patrick Wong, Jon Klein, Tiago B R Castro, Julio Silva, Maria Sundaram, Mallory K Ellingson, Tianyang Mao, Ji Eun Oh, Benjamin Israelow,[...]. Nature 2020
866
9

Anakinra for severe forms of COVID-19: a cohort study.
Thomas Huet, Hélène Beaussier, Olivier Voisin, Stéphane Jouveshomme, Gaëlle Dauriat, Isabelle Lazareth, Emmanuelle Sacco, Jean-Marc Naccache, Yvonnick Bézie, Sophie Laplanche,[...]. Lancet Rheumatol 2020
358
9

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults.
Romina Libster, Gonzalo Pérez Marc, Diego Wappner, Silvina Coviello, Alejandra Bianchi, Virginia Braem, Ignacio Esteban, Mauricio T Caballero, Cristian Wood, Mabel Berrueta,[...]. N Engl J Med 2021
424
9

Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.
Yeming Wang, Dingyu Zhang, Guanhua Du, Ronghui Du, Jianping Zhao, Yang Jin, Shouzhi Fu, Ling Gao, Zhenshun Cheng, Qiaofa Lu,[...]. Lancet 2020
9

A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.
Bin Cao, Yeming Wang, Danning Wen, Wen Liu, Jingli Wang, Guohui Fan, Lianguo Ruan, Bin Song, Yanping Cai, Ming Wei,[...]. N Engl J Med 2020
9

Endothelial cell infection and endotheliitis in COVID-19.
Zsuzsanna Varga, Andreas J Flammer, Peter Steiger, Martina Haberecker, Rea Andermatt, Annelies S Zinkernagel, Mandeep R Mehra, Reto A Schuepbach, Frank Ruschitzka, Holger Moch. Lancet 2020
9

Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study.
Giulio Cavalli, Giacomo De Luca, Corrado Campochiaro, Emanuel Della-Torre, Marco Ripa, Diana Canetti, Chiara Oltolini, Barbara Castiglioni, Chiara Tassan Din, Nicola Boffini,[...]. Lancet Rheumatol 2020
578
9

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.
Markus Hoffmann, Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Tanja Herrler, Sandra Erichsen, Tobias S Schiergens, Georg Herrler, Nai-Huei Wu, Andreas Nitsche,[...]. Cell 2020
9

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19.
David M Weinreich, Sumathi Sivapalasingam, Thomas Norton, Shazia Ali, Haitao Gao, Rafia Bhore, Bret J Musser, Yuhwen Soo, Diana Rofail, Joseph Im,[...]. N Engl J Med 2021
757
9

Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study.
Corrado Campochiaro, Emanuel Della-Torre, Giulio Cavalli, Giacomo De Luca, Marco Ripa, Nicola Boffini, Alessandro Tomelleri, Elena Baldissera, Patrizia Rovere-Querini, Annalisa Ruggeri,[...]. Eur J Intern Med 2020
246
9

Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Pierre-François Dequin, Nicholas Heming, Ferhat Meziani, Gaëtan Plantefève, Guillaume Voiriot, Julio Badié, Bruno François, Cécile Aubron, Jean-Damien Ricard, Stephan Ehrmann,[...]. JAMA 2020
218
9

A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia.
Ventura A Simonovich, Leandro D Burgos Pratx, Paula Scibona, María V Beruto, Marcelo G Vallone, Carolina Vázquez, Nadia Savoy, Diego H Giunta, Lucía G Pérez, Marisa Del L Sánchez,[...]. N Engl J Med 2021
449
9

Remdesivir for 5 or 10 Days in Patients with Severe Covid-19.
Jason D Goldman, David C B Lye, David S Hui, Kristen M Marks, Raffaele Bruno, Rocio Montejano, Christoph D Spinner, Massimo Galli, Mi-Young Ahn, Ronald G Nahass,[...]. N Engl J Med 2020
703
9

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.
Chaomin Wu, Xiaoyan Chen, Yanping Cai, Jia'an Xia, Xing Zhou, Sha Xu, Hanping Huang, Li Zhang, Xia Zhou, Chunling Du,[...]. JAMA Intern Med 2020
9

Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy.
Valentina Morena, Laura Milazzo, Letizia Oreni, Giovanna Bestetti, Tommaso Fossali, Cinzia Bassoli, Alessandro Torre, Maria Vittoria Cossu, Caterina Minari, Elisabetta Ballone,[...]. Eur J Intern Med 2020
122
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.