A citation-based method for searching scientific literature

Tamar Tchkonia, Allyson K Palmer, James L Kirkland. J Clin Endocrinol Metab 2021
Times Cited: 2







List of co-cited articles
9 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
205
100

Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
Juan Carlos Montero, Samuel Seoane, Alberto Ocaña, Atanasio Pandiella. Clin Cancer Res 2011
175
100

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
504
100



Senolytic drugs: from discovery to translation.
J L Kirkland, T Tchkonia. J Intern Med 2020
64
100

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
Jamie N Justice, Anoop M Nambiar, Tamar Tchkonia, Nathan K LeBrasseur, Rodolfo Pascual, Shahrukh K Hashmi, Larissa Prata, Michal M Masternak, Stephen B Kritchevsky, Nicolas Musi,[...]. EBioMedicine 2019
275
100

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
703
100

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
100

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
704
50

Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity.
Ann Hammarstedt, Silvia Gogg, Shahram Hedjazifar, Annika Nerstedt, Ulf Smith. Physiol Rev 2018
93
50

Pharmacokinetics and bioavailability of quercetin glycosides in humans.
E U Graefe, J Wittig, S Mueller, A K Riethling, B Uehleke, B Drewelow, H Pforte, G Jacobasch, H Derendorf, M Veit. J Clin Pharmacol 2001
349
50

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
804
50

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.
Carolyn M Roos, Bin Zhang, Allyson K Palmer, Mikolaj B Ogrodnik, Tamar Pirtskhalava, Nassir M Thalji, Michael Hagler, Diana Jurk, Leslie A Smith, Grace Casaclang-Verzosa,[...]. Aging Cell 2016
281
50

Upstream stimulatory factor-2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells.
Nélida C Olave, Maximiliano H Grenett, Martin Cadeiras, Hernan E Grenett, Paul J Higgins. J Cell Biochem 2010
15
50

Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin.
Seo Rin Kim, Kai Jiang, Mikolaj Ogrodnik, Xiaojun Chen, Xiang-Yang Zhu, Hannah Lohmeier, Leena Ahmed, Hui Tang, Tamara Tchkonia, LaTonya J Hickson,[...]. Transl Res 2019
32
50

Fat tissue, aging, and cellular senescence.
Tamara Tchkonia, Dean E Morbeck, Thomas Von Zglinicki, Jan Van Deursen, Joseph Lustgarten, Heidi Scrable, Sundeep Khosla, Michael D Jensen, James L Kirkland. Aging Cell 2010
534
50

Transplanting cells from old but not young donors causes physical dysfunction in older recipients.
Binsheng Wang, Zukai Liu, Vicky P Chen, Lichao Wang, Christina L Inman, Yueying Zhou, Chun Guo, Tamar Tchkonia, David W Rowe, George A Kuchel,[...]. Aging Cell 2020
12
50

Metformin inhibits chronic kidney disease-induced DNA damage and senescence of mesenchymal stem cells.
Hyoungnae Kim, Mi Ra Yu, Haekyung Lee, Soon Hyo Kwon, Jin Seok Jeon, Dong Cheol Han, Hyunjin Noh. Aging Cell 2021
2
50

Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Ming Xu, Allyson K Palmer, Husheng Ding, Megan M Weivoda, Tamar Pirtskhalava, Thomas A White, Anna Sepe, Kurt O Johnson, Michael B Stout, Nino Giorgadze,[...]. Elife 2015
224
50

p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.
Aharon Helman, Agnes Klochendler, Narmen Azazmeh, Yael Gabai, Elad Horwitz, Shira Anzi, Avital Swisa, Reba Condiotti, Roy Z Granit, Yuval Nevo,[...]. Nat Med 2016
133
50

Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence.
M Caron, M Auclair, B Donadille, V Béréziat, B Guerci, M Laville, H Narbonne, C Bodemer, O Lascols, J Capeau,[...]. Cell Death Differ 2007
138
50

Ink4a/Arf expression is a biomarker of aging.
Janakiraman Krishnamurthy, Chad Torrice, Matthew R Ramsey, Grigoriy I Kovalev, Khalid Al-Regaiey, Lishan Su, Norman E Sharpless. J Clin Invest 2004
920
50

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
50


Cellular Senescence: A Translational Perspective.
James L Kirkland, Tamara Tchkonia. EBioMedicine 2017
316
50

Metabolism and disposition of dasatinib after oral administration to humans.
Lisa J Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A Manning, Samuel J Bonacorsi, Michael Lago, Alban Allentoff, Francis Y F Lee, Betty McCann,[...]. Drug Metab Dispos 2008
116
50

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.
David E Harrison, Randy Strong, David B Allison, Bruce N Ames, Clinton M Astle, Hani Atamna, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, Nancy L Nadon,[...]. Aging Cell 2014
183
50

Reducing Senescent Cell Burden in Aging and Disease.
Robert J Pignolo, João F Passos, Sundeep Khosla, Tamara Tchkonia, James L Kirkland. Trends Mol Med 2020
23
50

The Clinical Potential of Senolytic Drugs.
James L Kirkland, Tamara Tchkonia, Yi Zhu, Laura J Niedernhofer, Paul D Robbins. J Am Geriatr Soc 2017
221
50

Targeting cellular senescence prevents age-related bone loss in mice.
Joshua N Farr, Ming Xu, Megan M Weivoda, David G Monroe, Daniel G Fraser, Jennifer L Onken, Brittany A Negley, Jad G Sfeir, Mikolaj B Ogrodnik, Christine M Hachfeld,[...]. Nat Med 2017
313
50

Safety Aspects of the Use of Quercetin as a Dietary Supplement.
Susanne Andres, Sophie Pevny, Rainer Ziegenhagen, Nadiya Bakhiya, Bernd Schäfer, Karen Ildico Hirsch-Ernst, Alfonso Lampen. Mol Nutr Food Res 2018
106
50

Cellular senescence drives age-dependent hepatic steatosis.
Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L Wilson, Albert Lahat, Christoper P Day, Alastair Burt, Allyson Palmer, Quentin M Anstee,[...]. Nat Commun 2017
295
50

The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia.
Lucy C Fox, Katherine D Cummins, Ben Costello, David Yeung, Rebecca Cleary, Cecily Forsyth, Maciek Tatarczuch, Kate Burbury, Olga Motorna, Jake Shortt,[...]. Blood Adv 2017
12
50

Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes.
Peter J Thompson, Ajit Shah, Vasilis Ntranos, Frederic Van Gool, Mark Atkinson, Anil Bhushan. Cell Metab 2019
79
50

A crucial role for adipose tissue p53 in the regulation of insulin resistance.
Tohru Minamino, Masayuki Orimo, Ippei Shimizu, Takeshige Kunieda, Masataka Yokoyama, Takashi Ito, Aika Nojima, Akira Nabetani, Yuichi Oike, Hisahiro Matsubara,[...]. Nat Med 2009
470
50

The role of the p53 tumor suppressor in metabolism and diabetes.
Che-Pei Kung, Maureen E Murphy. J Endocrinol 2016
65
50

Activin a plays a critical role in proliferation and differentiation of human adipose progenitors.
Laure-Emmanuelle Zaragosi, Brigitte Wdziekonski, Phi Villageois, Mayoura Keophiphath, Marie Maumus, Tamara Tchkonia, Virginie Bourlier, Tala Mohsen-Kanson, Annie Ladoux, Christian Elabd,[...]. Diabetes 2010
92
50

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.
Jingqi Fang, Jiping Yang, Xun Wu, Gangming Zhang, Tao Li, Xi'e Wang, Hong Zhang, Chih-Chen Wang, Guang-Hui Liu, Lei Wang. Aging Cell 2018
48
50

Discovery, development, and future application of senolytics: theories and predictions.
Erin O Wissler Gerdes, Yi Zhu, Tamar Tchkonia, James L Kirkland. FEBS J 2020
23
50

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Jasper Iske, Midas Seyda, Timm Heinbokel, Ryoichi Maenosono, Koichiro Minami, Yeqi Nian, Markus Quante, Christine S Falk, Haruhito Azuma, Friederike Martin,[...]. Nat Commun 2020
17
50

Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis.
Hiroshi Noto, Atsushi Goto, Tetsuro Tsujimoto, Mitsuhiko Noda. PLoS One 2012
367
50

Relevance of the p53-MDM2 axis to aging.
Danyi Wu, Carol Prives. Cell Death Differ 2018
67
50

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
Mikolaj Ogrodnik, Yi Zhu, Larissa G P Langhi, Tamar Tchkonia, Patrick Krüger, Edward Fielder, Stella Victorelli, Rifqha A Ruswhandi, Nino Giorgadze, Tamar Pirtskhalava,[...]. Cell Metab 2019
32
50

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463.
Yi Zhu, Ewald J Doornebal, Tamar Pirtskhalava, Nino Giorgadze, Mark Wentworth, Heike Fuhrmann-Stroissnigg, Laura J Niedernhofer, Paul D Robbins, Tamara Tchkonia, James L Kirkland. Aging (Albany NY) 2017
191
50

Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?
Sarah Anissa Hannou, Kristiaan Wouters, Réjane Paumelle, Bart Staels. Trends Endocrinol Metab 2015
74
50

Senescence and the SASP: many therapeutic avenues.
Jodie Birch, Jesús Gil. Genes Dev 2020
14
50

Role of p53 in preadipocyte differentiation.
Qiong Huang, Menglan Liu, Xinli Du, Rihua Zhang, Yi Xue, Yuanyuan Zhang, Weidong Zhu, Dong Li, Allan Zhao, Yun Liu. Cell Biol Int 2014
22
50

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation.
Olga Moiseeva, Xavier Deschênes-Simard, Emmanuelle St-Germain, Sebastian Igelmann, Geneviève Huot, Alexandra E Cadar, Véronique Bourdeau, Michael N Pollak, Gerardo Ferbeyre. Aging Cell 2013
220
50

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
Yi Zhu, Tamara Tchkonia, Heike Fuhrmann-Stroissnigg, Haiming M Dai, Yuanyuan Y Ling, Michael B Stout, Tamar Pirtskhalava, Nino Giorgadze, Kurt O Johnson, Cory B Giles,[...]. Aging Cell 2016
323
50


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.