A citation-based method for searching scientific literature

G J Cooper, A C Willis, A Clark, R C Turner, R B Sim, K B Reid. Proc Natl Acad Sci U S A 1987
Times Cited: 1119







List of co-cited articles
1301 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Islet amyloid polypeptide, islet amyloid, and diabetes mellitus.
Per Westermark, Arne Andersson, Gunilla T Westermark. Physiol Rev 2011
572
39

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.
P Westermark, U Engström, K H Johnson, G T Westermark, C Betsholtz. Proc Natl Acad Sci U S A 1990
637
25

Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.
Sorin Luca, Wai-Ming Yau, Richard Leapman, Robert Tycko. Biochemistry 2007
433
25

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus.
A Lorenzo, B Razzaboni, G C Weir, B A Yankner. Nature 1994
669
22

Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
16



Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.
Ping Cao, Peter Marek, Harris Noor, Vadim Patsalo, Ling-Hsien Tu, Hui Wang, Andisheh Abedini, Daniel P Raleigh. FEBS Lett 2013
130
14

Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Jed J W Wiltzius, Stuart A Sievers, Michael R Sawaya, Duilio Cascio, Dmitriy Popov, Christian Riekel, David Eisenberg. Protein Sci 2008
255
14

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.
Rehana Akter, Ping Cao, Harris Noor, Zachary Ridgway, Ling-Hsien Tu, Hui Wang, Amy G Wong, Xiaoxue Zhang, Andisheh Abedini, Ann Marie Schmidt,[...]. J Diabetes Res 2016
113
13

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.
Catherine A Jurgens, Mirna N Toukatly, Corinne L Fligner, Jayalakshmi Udayasankar, Shoba L Subramanian, Sakeneh Zraika, Kathryn Aston-Mourney, Darcy B Carr, Per Westermark, Gunilla T Westermark,[...]. Am J Pathol 2011
188
13

Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.
Andisheh Abedini, Annette Plesner, Ping Cao, Zachary Ridgway, Jinghua Zhang, Ling-Hsien Tu, Chris T Middleton, Brian Chao, Daniel J Sartori, Fanling Meng,[...]. Elife 2016
70
18

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.
Alexandra E Butler, Juliette Janson, Susan Bonner-Weir, Robert Ritzel, Robert A Rizza, Peter C Butler. Diabetes 2003
13

The amyloid formation mechanism in human IAPP: dimers have β-strand monomer-monomer interfaces.
Nicholas F Dupuis, Chun Wu, Joan-Emma Shea, Michael T Bowers. J Am Chem Soc 2011
155
12

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis.
Leena Haataja, Tatyana Gurlo, Chang J Huang, Peter C Butler. Endocr Rev 2008
407
12

Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment.
Ravi Prakash Reddy Nanga, Jeffrey R Brender, Subramanian Vivekanandan, Ayyalusamy Ramamoorthy. Biochim Biophys Acta 2011
170
12


Amylin: Pharmacology, Physiology, and Clinical Potential.
Debbie L Hay, Steve Chen, Thomas A Lutz, David G Parkes, Jonathan D Roth. Pharmacol Rev 2015
161
11


Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts.
K J Potter, A Abedini, P Marek, A M Klimek, S Butterworth, M Driscoll, R Baker, M R Nilsson, G L Warnock, J Oberholzer,[...]. Proc Natl Acad Sci U S A 2010
132
11

The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells.
Barbara Konarkowska, Jacqueline F Aitken, Joerg Kistler, Shaoping Zhang, Garth J S Cooper. FEBS J 2006
168
11

Pore formation by the cytotoxic islet amyloid peptide amylin.
T A Mirzabekov, M C Lin, B L Kagan. J Biol Chem 1996
338
11

Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process.
Jed J W Wiltzius, Stuart A Sievers, Michael R Sawaya, David Eisenberg. Protein Sci 2009
151
11

Amyloid fibril formation from full-length and fragments of amylin.
C Goldsbury, K Goldie, J Pellaud, J Seelig, P Frey, S A Müller, J Kistler, G J Cooper, U Aebi. J Struct Biol 2000
238
11

Mechanisms of islet amyloidosis toxicity in type 2 diabetes.
Andisheh Abedini, Ann Marie Schmidt. FEBS Lett 2013
114
11

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes.
Rebecca L Hull, Gunilla T Westermark, Per Westermark, Steven E Kahn. J Clin Endocrinol Metab 2004
362
11

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells.
S E Kahn, D A D'Alessio, M W Schwartz, W Y Fujimoto, J W Ensinck, G J Taborsky, D Porte. Diabetes 1990
374
10

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas.
P Westermark, C Wernstedt, E Wilander, K Sletten. Biochem Biophys Res Commun 1986
424
10

Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle.
G J Cooper, B Leighton, G D Dimitriadis, M Parry-Billings, J M Kowalchuk, K Howland, J B Rothbard, A C Willis, K B Reid. Proc Natl Acad Sci U S A 1988
376
10

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Seth L Masters, Aisling Dunne, Shoba L Subramanian, Rebecca L Hull, Gillian M Tannahill, Fiona A Sharp, Christine Becker, Luigi Franchi, Eiji Yoshihara, Zhe Chen,[...]. Nat Immunol 2010
842
10

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Rakez Kayed, Elizabeth Head, Jennifer L Thompson, Theresa M McIntire, Saskia C Milton, Carl W Cotman, Charles G Glabe. Science 2003
10

The β-cell assassin: IAPP cytotoxicity.
Daniel Raleigh, Xiaoxue Zhang, Benoît Hastoy, Anne Clark. J Mol Endocrinol 2017
54
18

Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.
Jeffrey R Brender, Edgar L Lee, Marchello A Cavitt, Ari Gafni, Duncan G Steel, Ayyalusamy Ramamoorthy. J Am Chem Soc 2008
176
10

Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition.
Xiaoxue Zhang, Johnna R St Clair, Erwin London, Daniel P Raleigh. Biochemistry 2017
57
17

Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet.
Lauren E Buchanan, Emily B Dunkelberger, Huong Q Tran, Pin-Nan Cheng, Chi-Cheng Chiu, Ping Cao, Daniel P Raleigh, Juan J de Pablo, James S Nowick, Martin T Zanni. Proc Natl Acad Sci U S A 2013
154
10

Islet amyloid and type 2 diabetes mellitus.
J W Höppener, B Ahrén, C J Lips. N Engl J Med 2000
373
10


The role of His-18 in amyloid formation by human islet amyloid polypeptide.
Andisheh Abedini, Daniel P Raleigh. Biochemistry 2005
133
10

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.
L M McLatchie, N J Fraser, M J Main, A Wise, J Brown, N Thompson, R Solari, M G Lee, S M Foord. Nature 1998
9


The Role of Cholesterol in Driving IAPP-Membrane Interactions.
Michele F M Sciacca, Fabio Lolicato, Giacomo Di Mauro, Danilo Milardi, Luisa D'Urso, Cristina Satriano, Ayyalusamy Ramamoorthy, Carmelo La Rosa. Biophys J 2016
45
20

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.
A Clark, C A Wells, I D Buley, J K Cruickshank, R I Vanhegan, D R Matthews, G J Cooper, R R Holman, R C Turner. Diabetes Res 1988
445
9

Role of zinc in human islet amyloid polypeptide aggregation.
Jeffrey R Brender, Kevin Hartman, Ravi Prakash Reddy Nanga, Nataliya Popovych, Roberto de la Salud Bea, Subramanian Vivekanandan, E Neil G Marsh, Ayyalusamy Ramamoorthy. J Am Chem Soc 2010
145
9

Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association.
Erika Andreetto, Li-Mei Yan, Marianna Tatarek-Nossol, Aleksandra Velkova, Ronald Frank, Aphrodite Kapurniotu. Angew Chem Int Ed Engl 2010
121
9

Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.
E T Jaikaran, C E Higham, L C Serpell, J Zurdo, M Gross, A Clark, P E Fraser. J Mol Biol 2001
183
9

Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide.
Jessica A Williamson, J Patrick Loria, Andrew D Miranker. J Mol Biol 2009
143
9

Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate.
Diana C Rodriguez Camargo, Kyle J Korshavn, Alexander Jussupow, Kolio Raltchev, David Goricanec, Markus Fleisch, Riddhiman Sarkar, Kai Xue, Michaela Aichler, Gabriele Mettenleiter,[...]. Elife 2017
45
20




Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.